Basic Information

Insect: Rhagium mordax
Gene Symbol: ZFHX3
Assembly: GCA_963680705.1
Location: OY796656.1:3434424-3448692[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0029 0.33 13.3 0.8 1 23 102 125 102 125 0.95

2 14 0.023 2.6 10.5 1.9 2 22 207 227 207 230 0.90

3 14 0.98 1.1e+02 5.3 1.7 1 23 242 267 242 267 0.91

4 14 0.0082 0.94 11.9 1.6 1 23 285 307 285 307 0.97

5 14 0.0018 0.2 14.0 0.7 2 23 314 336 313 336 0.94

6 14 0.00047 0.054 15.8 3.1 1 23 445 469 445 469 0.92

7 14 0.014 1.6 11.1 0.6 1 22 489 510 489 513 0.89

8 14 0.0028 0.32 13.3 0.2 1 23 562 586 562 586 0.93

9 14 0.0026 0.3 13.4 0.1 2 21 649 668 648 669 0.94

10 14 0.83 95 5.6 2.5 2 19 791 808 790 813 0.90

11 14 0.0003 0.034 16.4 2.5 1 23 1384 1406 1384 1406 0.99

12 14 0.0021 0.23 13.8 0.3 1 23 1503 1525 1503 1525 0.98

13 14 0.016 1.9 10.9 0.4 2 23 1674 1696 1673 1696 0.96

14 14 3.6 4.1e+02 3.6 3.2 3 23 1955 1977 1953 1977 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0029	0.33	13.3	0.8	1	23	102	125	102	125	0.95
2	14	0.023	2.6	10.5	1.9	2	22	207	227	207	230	0.90
3	14	0.98	1.1e+02	5.3	1.7	1	23	242	267	242	267	0.91
4	14	0.0082	0.94	11.9	1.6	1	23	285	307	285	307	0.97
5	14	0.0018	0.2	14.0	0.7	2	23	314	336	313	336	0.94
6	14	0.00047	0.054	15.8	3.1	1	23	445	469	445	469	0.92
7	14	0.014	1.6	11.1	0.6	1	22	489	510	489	513	0.89
8	14	0.0028	0.32	13.3	0.2	1	23	562	586	562	586	0.93
9	14	0.0026	0.3	13.4	0.1	2	21	649	668	648	669	0.94
10	14	0.83	95	5.6	2.5	2	19	791	808	790	813	0.90
11	14	0.0003	0.034	16.4	2.5	1	23	1384	1406	1384	1406	0.99
12	14	0.0021	0.23	13.8	0.3	1	23	1503	1525	1503	1525	0.98
13	14	0.016	1.9	10.9	0.4	2	23	1674	1696	1673	1696	0.96
14	14	3.6	4.1e+02	3.6	3.2	3	23	1955	1977	1953	1977	0.89

Sequence Information

Coding Sequence: ATGCCGTTAATCCCTGTCATTACTGCAACAATACCCACCCGAATTTTACCTCtaaaaatgttcttttattCTTCCACAGAGCGCCGAGATAGCATCAACTCCGAGCTCAGTCAAATCGAAGCGGGCAGAGATCAGGTCAAGTCGGAGCCGCGAGAGGAAGCCGACGATGCCAACAACAGCGAGAGCGGCTCCCCGCAGCACATGTGCCCGTTCTGCGAGTACAGCAGCGATTCGGAGATGCGCATCCAGGCGCACATCCTCGCCCAGCACGGCTCCAACAACGCGTCCATGCCCGAGATCCTCTTCCACTGCCCCTTATGCCAGGACGCCTTCAAGGACCGCACCAACTTGGAGCGCCACGTTATGCAGATACATTCCGTGAACAGCGAGGGCCTGCAGCGCCTACTGATGCTAGTGGATCAAAGTCACTGGCTGAACCAAGCCTCCAGAACGCCCACACCAAATAACTCTCTGAATCAAACCCAAACGACGCCTAATCAAATTATATCACCGACTTCAGTGTCTTCCAAAGAATCAAATAAGCTCGAGAGGAGCGCGGACGCCGAACCAGACTTGATGTCGCCCGTCAGCGACGACAACACCGAGTCCGAATCCGAGCGCTGCGGGACGTGTTCCAAGACATTTCGGAACATCGACGAACTGTGCTACCACCAAAACGAAACCGCACACCTGGAAATCAAGCAGACGCCCAGCGGGCCAGGCTACATGTGCTGGAAGAAGGGATGCAACCAGTTTTTTCCAACCGTACATACTCTACAAATGCATTTCAAGGAAGTACACGCCAAAAATTCGATCGCGAACATGTCGGTGTCGGAGAAGCACGTCTACAAGTACAGATGCAACCAGTGCTCCTTAGCCTTCAAGACGCTGGAGAAACTGCAACTCCATTCTCAGTATCATATGATCAGAGACGCTACAAAATGCGTGTTGTGTGGACGCAGCTTTAGATCGCTCGTCGCGTTGCATAAGCACGTTGAAAGCGTGCACTCGGAACTGACGGACGAAGAATTAAACGCTTACAAGCATAGCCTGATGAACAACCCCTTGCTGTTGGCTGGACTGCAAGGACAAGTGCTGGACAGTTCCACGAACGATATATTAAAGAAAGAGTCGCTGCGCCACGACGACAACGAGTCTGGCGAGTGCGACGACAGCAAGGAGCTGAACACTAGTCAATCGCTCGACGATAGCAATCAGAACGACGGGGAAAATTCGGACGACAGCATCATTTATAAAGACCAACAGTTCCTGGAAGATTACCTGAACAGCCAAGCCATCGCGGAGGACAGCTACAACGACCCTAATAGAAAATACAAATGCCACCGCTGCAAAGTAGCCTTCACAAGACAAAGCTATCTAACCGCTCATAACAAAACCCTTTTGCACCGAAAAGGCGAGAAACTGAGTTACCCTATGGAGAAATACCTGGACCCGAACAGACCCTACAAATGCGACGTATGTAAAGAGAGTTTCACACAGAAGAACATTCTACTCGTCCATTACAACTCGGTCAGTCATTTGCATAAATTAAAAAGGGCCATGCAAGAGCAGCAGAACAATAACAACAACCCCCCTGTGTCGCCCGTCACCGGAGGCGCCCAGCCGCAAAACCTGACGCTGACGCCGAAAAGCACTTCCTCGGAGGAAGACGACAAGAAGCGGTACCGCTGCAACATCTGCAAAGTGGCCTACACCCAGGGCAGCACCCTCGACATCCACATGAGGAGCGTCTTGCACCAGACCAGGGCGAGCAAACTGCAAGATTTAGCGATGGCCGGCCAGATCGACTTGTCCAAGCCCCTGATAGAACAGCCAGAAGCCATGCAGTCTCCGAAACAAACGAGTCCGGCGCCAGGTAGTGGGGACAAACAACCCTCTCCCACCCCTCCGTCACCTGGACTCTCAGGTAGTCAAGGGATGATGAGCTGCCCGAAATGTGGAGCGTTGTTCAGTTCTCAGGATCAGTTGAGTGCTCATCAGCAGCTGTACTGCATGTTCGCGGCGCCCATGGCGATTTTTCCAACGGCTCACGAGCCCAAAAGCCCTCCGCCCGGCGAAACGCAAGACGGCATCGTCAGGCTGAACATACCCAAGAAAACCGGCTCGCACATGTACAAACACCTCTTGGAAAGTTTCGGGTTCGACTTAGTGATGCAATACAATGAGAGCCACCAGCGGCGACAGAGGCAGCAGCGCGAGGCCGAAGAGAAGGCAGCCAGCGAGGCCCAgacgccgccgccgccgccgcccgCCTTGGAAGAGCCCGCTAACGAAACGGCGCCCACCGTGGATGGTGCAGAGGCCAAGGAGGAGGATATAGAAACCAACCTACCTGAAGTAAGTAAATCTACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTTCATAAAGATTTAGTGCCACTCGAATTCTTAGAAAAATATGCTCAACAGTTCAAAAACGAATACGAAAAGAAAACGGTGGTCGTGACGGCGGCGACGTCCTCAACGCTTAACACCATGCCTCGAGTGTCGACGCCGAGCGGAACGACGCCCACCACCACAGCCGCCTCCTCGTCCAGCCCCGCGGAGGCCGCCACTCCCGAGAAAGAGGACGAATCCAAAGAAACGTTGCACGCCAAGTTGAACCTTCACACCCCGCCCGAGGCGACCTCGACGGCCCCCTCGACCCCGACGTCCTCCACGACGCCCGCCAGCAGCACCGACTCGTTGCCCGCCAACATCCAGGCGATGATCGCCCAGAGCATGGCCCAAAATCCTATGGCTTTGGCGCAACAGATGAACGAAATGCAGGCGGCACTGAACGTGATGCAATTGCAACAGCTAAATTTTAATCCGATGATGCAGATGATGGGCATGGGCTTGCCATTAGGTCTGAATGCATTGGCGGCGATGAATCTGCAACCGCCTCTGGTTCCCCTGATGATGCCGCCCCCGCCGTACGATCCGATCTCGCAGTTCGGGCCGCAGGATCAACAGGCCATGCTCGCCAAACAGCAGCAGGCCATGATGCAGCAACAAGCGGCCGTAAACGCTGCTGCCAACCAGAAACGCGCCAGAACGCGAATCACCGATGATCAATTGAAAATTTTGCGTGCACACTTCGACATAAATAACTCCCCGTCAGAAGAGCAAATACACGAGATGGCATCGCAAAGCGGCCTGCCACCCAAAGTCATAAAGCACTGGTTCAGAAACACGTTATTCAAGGAGAGGCAGCGCAACAAGGACAGCCCTTATAACTTTAACAACCCGCCGTCGACGACGCTTAATTTGGAGGAGTACGAAAAAACTGGCGAGGCGAAAGTCATGCCGCTTAACAGCTCAGGTAGCAGCATCGAAGAGATCAAATCCAAGGACTCGCCTACTCCTATCCACCAAGAGATTAAAACCGAATTAAAAGAAGAGTTGCCCGAAGACCCGCCGCCGAAATACATAGAGGATAAGGCTCACGACTCGATCGACGATAAGCCTAACATGTTTAACTTGCCGCTTAATTTGCAGCCGCCTCAGAGCCCAGCTACCTCAGTGGCCAGCTCGGATAACCAGAGCGTATCGCAGCCGAGCACACCCAACAATCTCACCCTTACCTCAATTATCGCGTCGCAATTGGGCGACACGCTAACAACCAGCACACCAACCATGAACATGTCCAACATGTCGTCGCACCACGGATTGACAAGTCCGATGTTGCCACCACCTAAACTCAACCAGCAAAATTTTTCCAACCCTAACAGTCTCCAGGGAATCCTCCCGTTGACCCCTAATCGCTGCCTGAGCCCAAACAGAGAATACAGCAACCCCGGGAGTCAGGGATCGGGCGGGTCCACCGGCAAAAGAGCCAACCGCACCAGATTCACCGATTACCAGATAAAAGTCTTGCAAGAATTCTTCGAGAACAACGCCTATCCCAAAGACGACGACTTGGAATACCTTTCAAAACTATTAAACCTAAGTCCTAGAGTCATCGTGGTGTGGTTTCAGAACGCTCGCCAGAAAGCACGCAAAGTATACGAGAACCAACCAGCTGCTGAGCCTGCCCCTGGCATTCCCGACGAGGCAGGCGCAAACAGATTCCAGAGGACGCCCGGCTTAAACTACCAGTGCAAGAAATGCCTCCTGGTTTTCCAAAGATATTACGAGCTGATCAGGCATCAAAAAACGCATTGCTTCAAAGAAGAAGACGCCAAAAGATCGGCGCAGGCCCAGGCAGCAGCTGCGCAAATCGCTGCCGTCTTGAGCTCGGAAGACTCGAATTCAAGCACGACCGTGGAGCAGTCCTCGCAACAACCCCAACACCAGATGCAGCAACAATCCTCTATGCAACAAAACACGCAATCCAACCCTGCCCACAGCCCAAGCCCAAGCCAACCAAATCCTCCCACAACACCAACACCTAGCCAATGCAATTATCCTCCTTCCTCCCCGTCACCTTCGGAGTCCAAGGAGAGCACATTTCAATGCGACAAATGCAATCTAGTTTTTCCTCGATTCGAACTGTGGAGAGAACATCAGCTAGTCCACTTAATGAATCCCAACCTTTTTCCAACTTATCCCCCGGATTCTCCTTTTGGGATCCTTCAGCAGCACGCCCAACTCCAACAGCTAAACGCAAATTTGGGGGATTTAAAGCCACAAAACAATGCCACGCAGCAAAACATTCAACATCCACTGATAAACATGTTGAATAATGTGACTAGCCAGAAGAGAAAAATTGACGATTTCGACGCAGAAAGTGACACTTCTGACCAACCCAAGGATAAGAGACTAAGAACCACGATTTTACCAGAACAGCTAGATTACTTGTACCAAAAATACCAGATCGAGAGCAACCCTTCAAGAAAAATGTTGGAGAATATAGCCAGGGAGGTCGGCTTAAAAAAAAGGGTGGTCCAAGTCTGGTTTCAGAACACCCGGGCTAGAGAAAGGAAAGGGCAGTTTCGCGCTCACGCCCAAGTGATCAACAAGCGCTGCCCGTTTTGCCCTGCTCTGTTTAAAGTGAAGTCGGCTCTAGAATCTCATTTAACCACGAAGCACGCCGACCAGTGCGCCAGAGGCGAAATCAACATAGACGCTTTACCCGACGAAGAAATCAGCCTCGAGTCTGCGCCTAGCTTAAGTTCCGGAGGCGACAACAAATTCCAACAGCAGAACCCAAACATGATGCCACCACTTTTTCCTTCTCTTCACCCTGAAATGGAAAGTTCGATAAAGAAATACTACGAGGAGAGTATGAAGAGGTATATTAGCGAATTGCAAGCGCACGCCTCGTCGTCCAATGGCGACAAGAGCGAAATCAAATGCGAAAAAGGGGAAAGTGGTGAGATACCTTTGGACCTCTCCAAACCAGTAGACTTATCGAGACCTATGAAAGTATCCATGGATCACGAGCGCAACATGTGCGATCCCGGCCCGTTAACCGATCTCAGTGAACGATCTCTTTGCGACGAGAGGAGCGACTCGATGTCAGAAACCACCGAGTTCTATGACGACGAGAGCAACCCTACGTCGCCTGCCAGCAGCACCCAAAGCAACACACAAAGAATGAACAGCGGCACTTCCGTTGGAGGTACGAAGCGATTTCGTACGCAAATGTCCTCGGTTCAGGTGAAGGTAATGAAAATACTTTTTCACGACTACAAAACCCCGACAATGGCCGAGTGTGAGAGCTTAGGCAGAGAAATCGGCTTGCCCAAGCGCGTAGTGCAGGTGTGGTTCCAGAACGCCAGGGCGAAAGAGAAGAAGAGCAAAATGGCGTTGCAAAAAGTCCTCGGCCAGCCAGATTCGGAGAACCCGCCGCTGCCCGACGACTGCCGGTTCTGCAATTTCAAATACTCGCACAAGTACTCGATTCAAGACCACATCTTCACCAAAACTCACATAGCAAACGTAAGGATGCACCTGGAGAGCCAGCAAAGCAAAGAGGTTGGTCCGGAGGGCGAGTTCACGGTCCCACCCTTACCCGGAGTGTCCGGAGCCGTCACCGCCGACTCCACCACGAACCCGCCCCAGAACCTGAACAACAACACCCACCTCCAGTTGCTGCAGATGGCCGGCATGCAGATGGGGGCCGCTTCGAAGGGCGAGCAGGAGGAGAGTCCGGAGTCCCTGTTCCAGCAGCTGTACGCCTTGGGGAACAACGCCAACTTTGGGGTCCAGAACCAGTATGTCCACCACGCGATGTTTGGCGCCAATGGTGAGTTGAAAGCTTTGGTATTTGCTAGTTTTACAGTTTTGGGGGTAGGTACAGTCGTCCATGGTTTTAGAAATAAAGTAAAGGTATGA
Protein Sequence: MPLIPVITATIPTRILPLKMFFYSSTERRDSINSELSQIEAGRDQVKSEPREEADDANNSESGSPQHMCPFCEYSSDSEMRIQAHILAQHGSNNASMPEILFHCPLCQDAFKDRTNLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNSLNQTQTTPNQIISPTSVSSKESNKLERSADAEPDLMSPVSDDNTESESERCGTCSKTFRNIDELCYHQNETAHLEIKQTPSGPGYMCWKKGCNQFFPTVHTLQMHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKHSLMNNPLLLAGLQGQVLDSSTNDILKKESLRHDDNESGECDDSKELNTSQSLDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPPVSPVTGGAQPQNLTLTPKSTSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPEAMQSPKQTSPAPGSGDKQPSPTPPSPGLSGSQGMMSCPKCGALFSSQDQLSAHQQLYCMFAAPMAIFPTAHEPKSPPPGETQDGIVRLNIPKKTGSHMYKHLLESFGFDLVMQYNESHQRRQRQQREAEEKAASEAQTPPPPPPALEEPANETAPTVDGAEAKEEDIETNLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNTMPRVSTPSGTTPTTTAASSSSPAEAATPEKEDESKETLHAKLNLHTPPEATSTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMNEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPISQFGPQDQQAMLAKQQQAMMQQQAAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSIEEIKSKDSPTPIHQEIKTELKEELPEDPPPKYIEDKAHDSIDDKPNMFNLPLNLQPPQSPATSVASSDNQSVSQPSTPNNLTLTSIIASQLGDTLTTSTPTMNMSNMSSHHGLTSPMLPPPKLNQQNFSNPNSLQGILPLTPNRCLSPNREYSNPGSQGSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIPDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSSQQPQHQMQQQSSMQQNTQSNPAHSPSPSQPNPPTTPTPSQCNYPPSSPSPSESKESTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPTYPPDSPFGILQQHAQLQQLNANLGDLKPQNNATQQNIQHPLINMLNNVTSQKRKIDDFDAESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEISLESAPSLSSGGDNKFQQQNPNMMPPLFPSLHPEMESSIKKYYEESMKRYISELQAHASSSNGDKSEIKCEKGESGEIPLDLSKPVDLSRPMKVSMDHERNMCDPGPLTDLSERSLCDERSDSMSETTEFYDDESNPTSPASSTQSNTQRMNSGTSVGGTKRFRTQMSSVQVKVMKILFHDYKTPTMAECESLGREIGLPKRVVQVWFQNARAKEKKSKMALQKVLGQPDSENPPLPDDCRFCNFKYSHKYSIQDHIFTKTHIANVRMHLESQQSKEVGPEGEFTVPPLPGVSGAVTADSTTNPPQNLNNNTHLQLLQMAGMQMGAASKGEQEESPESLFQQLYALGNNANFGVQNQYVHHAMFGANGELKALVFASFTVLGVGTVVHGFRNKVKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00886822;
90% Identity: iTF_00886822;
80% Identity: iTF_01289568;