Basic Information

Insect: Cylas formicarius
Gene Symbol: Zfhx4
Assembly: GCA_029955315.1
Location: JARGXY010000010.1:8483611-8501213[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.13 10 7.2 0.6 2 23 107 129 106 129 0.93

2 14 1.1 92 4.2 2.5 2 21 206 225 206 229 0.87

3 14 0.056 4.5 8.3 1.3 1 23 241 266 241 266 0.92

4 14 0.0042 0.33 11.8 1.6 1 23 284 306 284 306 0.97

5 14 0.0009 0.073 13.9 0.7 2 23 313 335 312 335 0.94

6 14 0.00049 0.04 14.7 3.0 1 23 437 461 437 461 0.92

7 14 0.0071 0.57 11.1 0.6 1 22 481 502 481 505 0.89

8 14 0.0014 0.11 13.3 0.2 1 23 550 574 550 574 0.93

9 14 0.067 5.4 8.0 0.2 3 21 638 656 638 657 0.95

10 14 0.72 58 4.8 1.4 2 19 787 804 786 809 0.90

11 14 0.00015 0.012 16.4 2.5 1 23 1372 1394 1372 1394 0.99

12 14 0.001 0.084 13.7 0.3 1 23 1489 1511 1489 1511 0.98

13 14 0.0062 0.5 11.3 0.4 2 23 1661 1683 1660 1683 0.97

14 14 0.084 6.8 7.7 3.3 3 23 1945 1967 1944 1967 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.13	10	7.2	0.6	2	23	107	129	106	129	0.93
2	14	1.1	92	4.2	2.5	2	21	206	225	206	229	0.87
3	14	0.056	4.5	8.3	1.3	1	23	241	266	241	266	0.92
4	14	0.0042	0.33	11.8	1.6	1	23	284	306	284	306	0.97
5	14	0.0009	0.073	13.9	0.7	2	23	313	335	312	335	0.94
6	14	0.00049	0.04	14.7	3.0	1	23	437	461	437	461	0.92
7	14	0.0071	0.57	11.1	0.6	1	22	481	502	481	505	0.89
8	14	0.0014	0.11	13.3	0.2	1	23	550	574	550	574	0.93
9	14	0.067	5.4	8.0	0.2	3	21	638	656	638	657	0.95
10	14	0.72	58	4.8	1.4	2	19	787	804	786	809	0.90
11	14	0.00015	0.012	16.4	2.5	1	23	1372	1394	1372	1394	0.99
12	14	0.001	0.084	13.7	0.3	1	23	1489	1511	1489	1511	0.98
13	14	0.0062	0.5	11.3	0.4	2	23	1661	1683	1660	1683	0.97
14	14	0.084	6.8	7.7	3.3	3	23	1945	1967	1944	1967	0.90

Sequence Information

Coding Sequence: ATGAAACCCAACCTTTTTAGATGCGACCATGGCACTCACAAAGTCTTGATTTTTGAGGACCTTCCTTTAACTTTGCATCTGCACGTAGAACGCCGAGACAGTATCAACTCCGAACTGAGCCAGATCGAGGCCAACCGCGACCAAGTGAAATCCGAACCTCGGGAGGACACCGACGAACCGGGCTGCGAATCCTCCCAAATCCATCCCCACCTCTGTCCCTACTGCGAATACTCGAGCGACTCCGAAATGCGCATCCAAGCCCACGTGCTCGCGCAGCATTGCTCCGGTAGCGCGGGGAACGTCCAAGAAACGGTCATCCATTGCCCGTTGTGCCAAGATCTCTTCAAAGACCGTACCAGCCTCGAACGGCACGTGATGCAAATCCACTCGGTGAACAGCGAAGGCCTGCAGAGGCTGCTGATGCTCGTAGACCAGAGCCACTGGCTCAACCAAGCATCCAGGACGCCTACTCCCAACAATTCGGTGCCCAATCAGGTGTCACCCACGTCCGTATCTTCCAAAGACTCGAACAAGCTGGAGCGAAGCGCCGAAACGGAGGGCGAGCCCGATCTGCTGTCGCCATCTAGCGACGACAATGCGGAATCGGAATCCGAGCGTTGCGGCACGTGTTTCAAAACGTTTCGTAACATCGACGAGCTGTGTTTCCATCAGAACGAAACCGGTCACCTGGAGATCAAACAAACGCCGAGCGGACCGGGCTACGTGTGCTGGAAGAAAGGTTGCAACCAGTTTTTTCCAACCGCGCACACCCTGCAGATGCACTTCAAAGAGGTCCACGCGAAGAACTCGGTGTGCAACATGTCCGTCTCAGAGAAACACGTGTACAAGTACAGATGCAATCAGTGCTCGCTCGCGTTTAAGACCCTCGAGAAGTTGCAACTCCACTCGCAGTACCATCTGATCCGAGACGCGACCAAGTGCGTTTTGTGCGGGAGGAGCTTCAGGTCGCTAGTCGCGTTGCACAAGCACGTCGAGAGCGTCCACTCGGAGCTCACCGACGAAGAGCTGAACGCTTACAAGCAGAGCCTTATGAATAACCCCCTCCTGCTCGCCGGGTTACAAGGACAGATCCTCGACAGCTCGACGAACGATCTGCTGAAGAAGGAGTCGATGAGGGGCGACGAGAACGAGTGCGAGGACGCGAAAGATGCCACGCTGGACGACGGCAATCAAAACGACGGCGAGAACTCGGACGACAGTATCGTCTACAAGGACCAGCAGTTCTTGGAAGACTACCTGAACAGCCAAGCGATCGCCGAGGACAGTTACAACGATCCGAATCGAAAGTACAAGTGCCACCGTTGTCGGGTGGCATTCACGCGACAAAGCTACCTAACGGCGCACAACAAAACGCTCCTGCATCGCAAAGGCGAAAAACTGAGCTATCCGATGGAGAAATACCTCGACCCGAACCGCCCGTACAAGTGCGACGTGTGCAAGGAGAGTTTTACGCAGAAGAACATCCTGCTGGTGCATTATAACTCGGTGAGCCACCTGCACAAGCTAAAGCGCGCGATGCAGGAGCAGcagaacaacaacaacaacccgCCGATCTCGCCGGTCCAAGCTCAAAACTTGTCGCTGACGCCGAAGGGCGCGTGCGGCGACGAAGACGACAAGAAAAAGTACCGTTGCAACATCTGCAAAGTGGCGTATACGCAGGGTAGCACGCTCGACATCCACATGCGCAGCGTGCTCCACCAGACGCGCGCTAGCAAGCTCCAAGATTTGGCGATGGCCGGTCAGATTGACCTCACGAAACCGCTGATAGAACAACCGGAGGCCGTGCAGTCTCCGAAACAGTCGAGTCCCGCGCCAGGTAGTGGGGACAAACAACCCTCTCCCACCCCGCCGTCGCCCGGTCTCTCAGGTAGTCAAGGGATGACGGGGTGCTCGAAATGCGGCTCGCTATTCAATTCGCAAGATCAGTTGAGCGCGCACCAGCTCTACTGCATGTTCGCGGCCCCGATGGCCATATTTCAAAACGCGAGCGAACCGAACCAGGCGAAGAGTCCGCCTCCGATCGAAGACCAATCGAAACTGAACATGTCCAACAATAAAAAGGGTTCGCACATCTATAAACATTTGCTCGAGGGGTTCGGGTTCGACTTGGTGATGCAATACAACGAGAGCCACCAGAGGAGGCAGCGGCAGCAGCAACGCGAAGCCGAAGAAAAGGCCGCGGAAGCGGAGGCGGCGGCCGCGGTGGCGGCCAGCGCCGCGGAAGAGATCCCGGAGACGCCGGTACCAGCGGTATCCGAAGAACAAGCCGAACCGGCGAAAGACGCAACCGAAGAAGGCGGCGACGTCGCCAGTTTGCCCGAAGTAAGTAAATCGACCTGTCAGACGTGCAACAAAGAGTTCTCGAGTGTGTGGGTGCTCAAGTCTCACTGTGAGGAGGTGCACAAGGACCTGGTGCCGCTCGAATACTTAGAAAAGTATGCTCAACAGCTGAAAAACGAGATCGAAAAGAAAACCGTGGTCGTGACCGTGGCGACGTCGTCGACGAACAACACGCAACCGCGAGTGACTACCCCGACCGCCACGCAAAGTCCCGCCGCCGCGGAAAACGCGACCCCCGACAAGGAGGACGAGTCCAAGGACGTCCTCCACGCGAAACTTAACCTCCAAACGCCTCCGGAGGCGACCTCGACCGCGCCTTCGACGCCGACCTCTTCGACTACGCCGGCCAGCAGCACCGATTCGCTGCCGGCGAATATCCAGGCGATGCTCGCGCAGACCATGGCTCAGAATCCGATGGCGCTCGCTCAGCAAATGTCCGAGATGCAGGCCGCCTTCAACGTGATGCAGCTGCAGCAGCTCAACTTCAATCCGATGATGCAGATGATGGGAATGGGGTTGCCGCTGGGGCTGAACGCCCTGGCGGCGATGAACCTGCAGCCGCCACTGGTGCCGTTGATGATGCCGCCGCCGCCGTACGACCCGATGAGCCAGTTCGGGCCGCAGGATCAGCAGGCCATCTTGGCCAAACAACAGGCGGCCATGATGCAGCAGCAGGCGGTCGCGAACGCAGCCGCGGCCAATCAAAAACGAGCCCGTACCCGAATCACCGACGAACAGTTGAAAATTTTGCGCGCCCACTTCGACATCAACAACTCCCCTTCGGAAGACCAGATCCACGAGATGGCCACCCAGAGCGGGTTGCCGCCCAAAGTGATCAAACACTGGTTCCGAAACACCCTCTTTAAAGAACGCCAACGTAACAAAGACAGTCCTTACAACTTCAACAACCCCCCGAGCACGACACTGAACTTGGAAGAGTACGAGAAAACTGGCGAAGCGAAAGTGATGCCGCTGAACAGCTCGGGTAGCAGTAGCGACGAGCAAAACAAGAGTAAAGAGTCGTCGTCGCCGCTTCAACAGCCCGAGATCAAAGCGGAAATCAAAGAAGAGCCGGCGGAAGAGCCCCAAACGCAACACCAGCAGCCGAAATTCGAGGACAAACCCGCCGAAGAAAAGCTGAACATATTCAACCTGCCTCCGAACTTGCAGACGCCTCAAAGTCCCGCCACTTCTGTCGCGTCGAGCGAGGGCATGACCATGTCTCAGCCCACCACTCCCAACAACCTAACGCTGACGTCGATCATCGCGTCGCAACTTGGTGACACCTTAACGACGAGCACGCCCACTATGAACATGCAAACCCACCACGGTCTGAGCAGTCCTATGTTGCCGCCACCCAAAATCAACcaacaaaattttccaaatccCGGGACTCTGCAGGGGATGCTTCCCATGACCCCGAACCGATGCCTGAGCCCTAACAAAGACTACTGCTCGAATAGTCAAGGTTCAAGCGGCTCGACTGGCAAACGAGCCAACCGTACGCGATTCACCGACTACCAAATTAAGGTGCTGCAGGAGTTTTTCGAGAACAACGCGTACCCCAAGGACGACGACTTGGAATACTTGTCCAAACTGCTCAATCTCAGCCCTAGAGTGATCGTGGTGTGGTTCCAAAATGCCAGACAGAAAGCCCGGAAAGTGTACGAGAATCAACCGGCCGCGGAACCCGCTCCGGGTATCGATGAGTCCGGCGCCAACAGGTTCCAGCGAACCCCCGGCCTCAACTATCAGTGCAAGAAATGCCTGCTTGTTTTCCAACGATACTACGAACTGATCCGTCATCAGAAAACTCACTGCTTCAAAGAGGAGGATGCTAAGCGGTCCGCGCAGGCTCAAGCGGCCGCTGCCCAAATAGCTGCCGTTTTGAGTTCGGAGGACTCTAATTCCAGCACCATCGCCGAACAGTCGCAGCAGCAACAGCTACAGACGCAACCCCAAAACTTAACACAACAATCGAGTTCGCAACCTAGCTCGGCTCACAGCCCTGTCCCGCCGAATCAACCTACTACTCCTACCCCGAGCCAGATGAACTACCCGGCTACGTCGCCATCGCCGTCAGATACGAAGGAAGGCACGTTCCAGTGCGACAAGTGCAACCTCGTCTTCCCCAGGTTCGAGTTATGGCGCGAGCATCAGCTGGTTCACTTGATGAACCCCAACCTGTTCCCTTCGTATCCTCCGGACTCTCCGTTCGGGATTCTGCAGCAGCACGCTCAACTTCAGCAGTTTGGGGTTAATTTGGGCGAGATGGCGAAACAGAACGCGAACGCTCCCACCCCCAACGTGCCCCACCCGTTGATAAACATGCTGAATAACGTTACCGGACAGAAGAGGAAAATCGAAGACTTTGACGGCGAAAGCGACACGTCAGATCAACCCAAAGACAAACGTCTAAGGACAACTATTCTACCCGAACAGTTGGATTACCTCTACCAGAAGTACCAGATCGAAAGTAACCCGTCGAGGAAAATGTTGGAGAATATCGCCAGGGAGGTCGGCTTGAAGAAACGCGTGGTACAGGTTTGGTTCCAAAACACCCGTGCTCGGGAAAGGAAGGGTCAGTTTAGAGCCCACGCCCAAGTGATTAATAAGAGGTGTCCATTTTGCCCGGCCTTGTTCAAAGTGAAGTCCGCGCTAGAGTCGCATCTGAGCACGAAACACGCCGATCAATGCGCGAGGGGCGAGATCAACATCGACGCTTTACCTGATGAGGAGATTAGCCTGGAGTCGGCCCCCAGCTTGAGCAGCGGCGGCGATAGCAAGTTCCAGCAGAACCCAAACATGATTCCGCCGCTTTTCCCGCAGCTGCATCCCGACATGGAGAGCTCCATTAAAAAGTACTACGAGGAGAGCATGAAGAGGTACATCAACGAACTGCAGCAACACGCCTCCTCGTCTTCCAACGGTGACAAGAGCGAGATAAAGTGTGAAAAGGGGGAAGGCGGTGAGATCCCATTGGATCTATCGAAACCGGTGGACTTGTCCCGCCCTATGAAAGTGTCCATGGAACACGAGAGAAATTTGTGCGATCCGGGGCCACTGACAGATCTGAGCGAGCGTTCTCTGTGCGACGAAAGGAGCGACACCATGTCTGAGACGACTGAATTCATAGACGACGAGAGCAACCCGACCTCTCCCGCTAGTAGTACCCAGAGCAATACCCAACGCCAGATGAATACCAGCGGCGGTTCCCAGCACGGAGGCGCCAAACGGTACCGCACCCAAATGTCTTCGGTGCAGgtgaaaatcatgaaaattttgttcgGCGATTACAAAACGCCCACGATGGCCGAGTGCGAGAGTTTGGGCAGAGAAATCGGACTTCCCAAGCGGGTGGTGCAAGTGTGGTTCCAAAACGCTAGGGCCAAAGAGAAGAAGAGCAAGCTGGCCTTGCAAAAGGCCCTCGGACAGCCGGATAACGATAACCCGGTACTGCCGGAAGACTGCAAGTACTGCAACTTCAAGTACTCGCACAAGTACTCGGTACAAGACCACATATTCACCAAGAGCCACATCGGGAACGTGCGCGCGCACCTCGAAAATCAAGGCACCAAGGAAACCGGCGAGGGAGGAGAGTTCACCATACCGCCGCTTCCCGGAGCTTCTAGCACGGCCGATTCGACCACCGCGAATCAGCAACAGCAGCAGCAGCCGCAGAACATCAACAACAACACTCACATGCAATTGCTGCAGATGCAGATGGCCGGGATGCAGATGACCGGGGCTCAGGTGGCGGCCGCCCAGAAGGGGGAGCAAGAGGAGAACCAGGACAGCCTGTTTCAGCAGCTCTACAGTCTGAGCAACAGTCCCGGGTTCGGTGTTCAGAACCAATACGTCCACCATGCGATGTTCGGCGCGAACGGCCGTGGCGGTGGGGGGCCGGCCCTCCATATCGGGTTAATTATGACGTTTCGGAATGATAAACGAGAGGCGCATCAGGCCGCGGAAATTCCGTTATCTCGGCAAGAAAAGAAAACGCCCGAGAGGGGAGTGGGCGGCTGCGGGGGTAGTTCGCTCCGAAGGGAAAACGTTGTAATAGGACGTGCGGCATATATTATTGACGGGCCTCCCCCCCCACTTCCCGTTGTTTCGATGGAGTAA
Protein Sequence: MKPNLFRCDHGTHKVLIFEDLPLTLHLHVERRDSINSELSQIEANRDQVKSEPREDTDEPGCESSQIHPHLCPYCEYSSDSEMRIQAHVLAQHCSGSAGNVQETVIHCPLCQDLFKDRTSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNSVPNQVSPTSVSSKDSNKLERSAETEGEPDLLSPSSDDNAESESERCGTCFKTFRNIDELCFHQNETGHLEIKQTPSGPGYVCWKKGCNQFFPTAHTLQMHFKEVHAKNSVCNMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQILDSSTNDLLKKESMRGDENECEDAKDATLDDGNQNDGENSDDSIVYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCRVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPPISPVQAQNLSLTPKGACGDEDDKKKYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLTKPLIEQPEAVQSPKQSSPAPGSGDKQPSPTPPSPGLSGSQGMTGCSKCGSLFNSQDQLSAHQLYCMFAAPMAIFQNASEPNQAKSPPPIEDQSKLNMSNNKKGSHIYKHLLEGFGFDLVMQYNESHQRRQRQQQREAEEKAAEAEAAAAVAASAAEEIPETPVPAVSEEQAEPAKDATEEGGDVASLPEVSKSTCQTCNKEFSSVWVLKSHCEEVHKDLVPLEYLEKYAQQLKNEIEKKTVVVTVATSSTNNTQPRVTTPTATQSPAAAENATPDKEDESKDVLHAKLNLQTPPEATSTAPSTPTSSTTPASSTDSLPANIQAMLAQTMAQNPMALAQQMSEMQAAFNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPMSQFGPQDQQAILAKQQAAMMQQQAVANAAAANQKRARTRITDEQLKILRAHFDINNSPSEDQIHEMATQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSSDEQNKSKESSSPLQQPEIKAEIKEEPAEEPQTQHQQPKFEDKPAEEKLNIFNLPPNLQTPQSPATSVASSEGMTMSQPTTPNNLTLTSIIASQLGDTLTTSTPTMNMQTHHGLSSPMLPPPKINQQNFPNPGTLQGMLPMTPNRCLSPNKDYCSNSQGSSGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIDESGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTIAEQSQQQQLQTQPQNLTQQSSSQPSSAHSPVPPNQPTTPTPSQMNYPATSPSPSDTKEGTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQQFGVNLGEMAKQNANAPTPNVPHPLINMLNNVTGQKRKIEDFDGESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINIDALPDEEISLESAPSLSSGGDSKFQQNPNMIPPLFPQLHPDMESSIKKYYEESMKRYINELQQHASSSSNGDKSEIKCEKGEGGEIPLDLSKPVDLSRPMKVSMEHERNLCDPGPLTDLSERSLCDERSDTMSETTEFIDDESNPTSPASSTQSNTQRQMNTSGGSQHGGAKRYRTQMSSVQVKIMKILFGDYKTPTMAECESLGREIGLPKRVVQVWFQNARAKEKKSKLALQKALGQPDNDNPVLPEDCKYCNFKYSHKYSVQDHIFTKSHIGNVRAHLENQGTKETGEGGEFTIPPLPGASSTADSTTANQQQQQQPQNINNNTHMQLLQMQMAGMQMTGAQVAAAQKGEQEENQDSLFQQLYSLSNSPGFGVQNQYVHHAMFGANGRGGGGPALHIGLIMTFRNDKREAHQAAEIPLSRQEKKTPERGVGGCGGSSLRRENVVIGRAAYIIDGPPPPLPVVSME

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00886822;
90% Identity: iTF_00413310;
80% Identity: iTF_00413310;