Dsta009959.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila stalkeri
Gene Symbol
-
Assembly
GCA_035047405.1
Location
JAWNPR010000090.1:10160804-10163157[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 9.5 6.9e+02 1.1 4.2 2 23 285 307 284 308 0.91
2 10 0.026 1.9 9.2 1.1 6 23 316 333 316 333 0.98
3 10 0.00015 0.011 16.2 2.8 1 23 339 362 339 362 0.93
4 10 0.00037 0.027 15.0 2.2 1 23 370 392 370 392 0.96
5 10 0.00023 0.017 15.7 0.5 2 23 398 420 397 420 0.96
6 10 0.16 11 6.7 0.1 2 23 426 447 425 447 0.95
7 10 0.56 41 5.0 4.1 2 23 456 477 455 477 0.91
8 10 0.00011 0.0078 16.7 0.9 2 23 485 507 484 507 0.95
9 10 1.4e-05 0.001 19.5 0.5 3 23 515 535 514 535 0.99
10 10 0.00016 0.012 16.2 6.3 1 23 541 564 541 564 0.98

Sequence Information

Coding Sequence
ATGATTTGCCGTCTGTGCCTGAACAGCGCCAGCGACaccattcaaatatttgaaggCGTCGGCTTGACCCTGAACGTTGCTGCAGTGCTGGCCAAATATTTCTGGTTTGAGCCAAAATGTGATGATCCCATATCGACGGACATTTGCGTGGGCTGCTGGACGCGCGTCAGCGATTTTAATAAGTTCTACGCAAGTGTGGAGAAGGCGCATCGACTGCTCACCGAAAGATTCTCCATTAAAGTAGGCGATCAGCAGGAGAGAGATGAGAGGCTCAATCCACGGAGCAACAATGCCGAGCAGAAGCAGGAAGAACATGAAAAACAAGAAGATTCGAAAGATTTTCTTATTCAAAGCGAATGCGATGCTGATGCCGACGCCGAGGAGGATTTAGCAAATGAGGAACAAATGCCCACGGTGGAGGCTTTATATACGAGTGGAAATGAGAGCGACGCGGCTGCATCGTTTAGCAATGAACAGTTTCTGAACGATGTGCTGGCTCAACAGGGAGAGCCAGTTGCCGAGGCCGAGGCCGAGACCGAGACCGAGGCTGTGACAGCCGAACAAGTGCCGATCATAGAAAGTGTACCGCAAGAGCGTCGGGAGACGCGCTCCACACGCTCCAAGAGCAAAGCTCAGCAAGTGACAGAAGCTGcaacgactgctgctgctgctacgtcTACTGCTACTGCAGCCGAGCAGCCGACGCCTGCGAAACGTCGAGGCCGCTCAAAAGCCGAAAAGGTTAGTCCCAATGCCAATACCGAAGAGGAATTGCCGAAGGGCAAACGCTATGTGGATTATAAGAAATCGATGCAAGAGATCGATCAGAAAATCGCCCAACATATGCGTCTCACCTGCAGCATTTGCCACGAGGGCCAGGAGACATTCCTGACGCTCTGCAAGCACATGATGCTTGTGCATCATCGCAAGGGCTATGCCGTCTGCTGTAACAAGAAGTTCTACAAACGTTCCTTTCTCACCGATCACATCGATCGCCATTCGAATCCCGAGAAATTCAAATGCGACTTGTGCGATCGCACCTTTGCGGACAAGCAATGCCTGCGCAATCACGAGCTGTTAAAGCATCAGCCGGACGAACAAAAGAAATTCATGTGCGAACACTGTCCGAAGCGCTATACGAAGCAGTATTTATTGGATCAGCATAGGGTCATACACAAAGAGCGCAATGTGCCATGCGATATATGCGAGCGGCGTTTTCCCAACATGTCGATGCTGTGCACCCATGTCAAGATGGTTCATGGCAACTATGGCACCATGTGCGACATTTGTGCCCAGGTGATACGCGGACGTGCCGCCTTTCAGCGCCATCAGCTGGAGCATGCTGGCATTACGGAGCCCAAGGTGCAGTGTGACATCTGTGGGTCGTGGCACAAGAATAAGTATAGCCTAAAGAAACATGTGCGACGGCACAATGGCTCGTCCGAGGAGTGCACTTGCAACATTTGTGGCAAGGTCTCGCCCAATCGGAGTGCCATGCTCAGCCATCAGCGTTATGTGCACAATGCGGATCGTGTGCATGGCTGTAGCGTGTGCAAGAAGATGTTCAAGAAGGCCATCAATCTGAAGGAGCACATGGCCACGCATACCGGCGAGGTGCTCTACAAGTGTCCACATTGTCCCAAGACCTTCAATTCGAATGCGAACAAGCATTCGCATCGCAAGAAGAGCCATCCCAAGGAGTTTGAGGAGGCGCGTAAGGCGCGCATGCAAAATCGCATGGGCATGGATAATAGTAAGAGTAACCAGACGACGAGCATGATAACCATAACAACTGATGCCAGTGATGGCCAGCTGGAGACGCACAATATACTGGTGACAACCAGCTCGGCACAGCATCCCGATGACGATGAAGAGGATTTCAAGGGCGAGGACATTGAGTACATGCTCACGCTCAGTCCACAGCCAGCGGAGTAG
Protein Sequence
MICRLCLNSASDTIQIFEGVGLTLNVAAVLAKYFWFEPKCDDPISTDICVGCWTRVSDFNKFYASVEKAHRLLTERFSIKVGDQQERDERLNPRSNNAEQKQEEHEKQEDSKDFLIQSECDADADAEEDLANEEQMPTVEALYTSGNESDAAASFSNEQFLNDVLAQQGEPVAEAEAETETEAVTAEQVPIIESVPQERRETRSTRSKSKAQQVTEAATTAAAATSTATAAEQPTPAKRRGRSKAEKVSPNANTEEELPKGKRYVDYKKSMQEIDQKIAQHMRLTCSICHEGQETFLTLCKHMMLVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCDLCDRTFADKQCLRNHELLKHQPDEQKKFMCEHCPKRYTKQYLLDQHRVIHKERNVPCDICERRFPNMSMLCTHVKMVHGNYGTMCDICAQVIRGRAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGSSEECTCNICGKVSPNRSAMLSHQRYVHNADRVHGCSVCKKMFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKSHPKEFEEARKARMQNRMGMDNSKSNQTTSMITITTDASDGQLETHNILVTTSSAQHPDDDEEDFKGEDIEYMLTLSPQPAE