Basic Information

Insect: Drosophila virilis
Gene Symbol: grau
Assembly: GCA_007989325.2
Location: CM017608.2:12001583-12003878[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 9.2 5.5e+02 1.0 4.1 2 23 255 277 254 278 0.91

2 10 0.022 1.3 9.3 1.1 6 23 286 303 286 303 0.98

3 10 0.00012 0.0073 16.4 2.8 1 23 309 332 309 332 0.93

4 10 0.00015 0.0086 16.2 2.3 1 23 340 362 340 362 0.97

5 10 0.00022 0.013 15.6 0.3 2 23 368 390 367 390 0.96

6 10 0.13 7.9 6.8 0.1 2 23 396 417 395 417 0.95

7 10 0.58 34 4.8 4.4 2 23 426 447 425 447 0.91

8 10 0.00013 0.0079 16.3 0.9 2 23 455 477 454 477 0.95

9 10 7.9e-06 0.00047 20.1 0.6 3 23 485 505 484 505 0.99

10 10 0.00095 0.056 13.6 8.9 1 23 511 534 511 534 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	9.2	5.5e+02	1.0	4.1	2	23	255	277	254	278	0.91
2	10	0.022	1.3	9.3	1.1	6	23	286	303	286	303	0.98
3	10	0.00012	0.0073	16.4	2.8	1	23	309	332	309	332	0.93
4	10	0.00015	0.0086	16.2	2.3	1	23	340	362	340	362	0.97
5	10	0.00022	0.013	15.6	0.3	2	23	368	390	367	390	0.96
6	10	0.13	7.9	6.8	0.1	2	23	396	417	395	417	0.95
7	10	0.58	34	4.8	4.4	2	23	426	447	425	447	0.91
8	10	0.00013	0.0079	16.3	0.9	2	23	455	477	454	477	0.95
9	10	7.9e-06	0.00047	20.1	0.6	3	23	485	505	484	505	0.99
10	10	0.00095	0.056	13.6	8.9	1	23	511	534	511	534	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTAAACAGCGCAAGCGACACCATTCAAATATTTGATGGCGTCGGCTTGTCCCTAAACGTAGCCACAGTGCTGGCCAAGTATTTTTGGTTTCAgCCGAAAAGCGATGATCCCATATCGACGGACATTTGTGTGGGCTGCTGGACGCGTGTCAGCGACTTTAACGAGTTCTATGCCAGCGTGGAGAAGGCGCATCGTCTGCTCACCGAGAGATTCTCTATCAAAGGCGGCGAACAGCCGGAGCGGGTTaccacaagcagcagcagttcggTAGCAGGCGAGCAGAAGCAGGAAAAGCAGGAGGACACAAAGGACTTTCCTCTGCACAGCGAATGCGACGCCGAGGAAGACTTGGCTCAAGAGAACGACCATGCTGTGGAGGCTATGTACGCCAGCGGCAGCGAGAGCGATGCAGCTGCATCATTCAGCAACGAGCAGTTCCTCAACGATGTGCTGGCCCAGCAGCAAGATGCTGATGTACACACGACAGACTCGCCCGATGAGCCGGACCAAACCGCGGCACCACAGGCTATGCAAGAGCGTCGTGAAACGCGCTCAACGCGCGCCAAAAGCAAAGCCCAacaagctgctgcagctgagcagCCTGTGCCAGCCAAGCGACGAGGTAGGTCGAAGCCCGAGAAAATCAACCGAAGCGCCGAGGAATTGCCAAAGAACAAACGCTATGCAGATTACAAGAAATCCATGCTGGAGATCGATGAGAAGATAGCGCAACATATGCGGCTCACCTGCAGCATTTGCCACGAGGGACAGGAGACGTTTCTACTGCTCTGCAAGCACATGATGCAGGTGCACCATCGCAAGGGCTATGCGGTGTGCTGCAACAAGAAGTTCTACAAACGTTCCTTTCTCACAGATCACATAGATCGCCACTCGAATCCCGAGAAATTTAAGTGCGAGCTCTGCGACAGAACCTTTGCGGACAAACAGTGTCTGCGCAATCACGAGCTGCTCAAGCATCAGCCGGACGAGCAGAAGAAGTTCATGTGCGAGCATTGTCCCAAGCGCTATACAAAGCAGTATTTATTGGATCAGCATAGAATAATACACAAGGAGCGCAACGTGCCTTGCGATATATGCGAGCGGCGATTTCCCAACGTTTCAATGCTCTGCACGCACGTCAAGATGGTGCACGGTAACTATGGCACCATGTGCGACATATGCGCCCAGGTGATACGAGGACGCGCTGCCTTTCAGCGCCATCAGCTGGAGCATGCTGGCATTACGGAGCCCAAGGTGCAGTGCGACATATGCGGCTCGTGGCACAAGAACAAATATAGTCTAAAAAAGCATGTGCGACGGCACAACGGCTCCTCCGAGGAGTGCACCTGCAGCATATGCGGCAAGGTGTCGCCCAATCGCAGCGCGATGCTCAGCCACCAGCGCTATGTACACAATGCGGATCGGGTCCATGGCTGCAGTGTGTGCAATAAGAAGTTCAAAAAAGCCATCAATCTCAAAGAGCACATGGCCACGCACACAGGCGAGGTGCTCTACAAGTGTCCGCACTGTCCGAAGACCTTCAATTCGAATGCCAACAAGCATTCGCATCGAAAAAAGTGCCATCCTAAGGAGTTTGAGGAGGCGCGCAAGGCCCGCATGCAAAATCGCATGGGCGACAACACAAGCCCAAGCAAATCTCAAACGAGCCTGATAACCATTACCACGGGCGAGACAGACGGCGAGCTGGAGACGCACAATATACTCGTAACCACGACGGCAGAGCACAGCGATGGTGATTTCAAGGGCGAGGACATTGAGTTCATGCTCACACTCAGTCCACAGCCGGCGGAATAG
Protein Sequence: MICRLCLNSASDTIQIFDGVGLSLNVATVLAKYFWFQPKSDDPISTDICVGCWTRVSDFNEFYASVEKAHRLLTERFSIKGGEQPERVTTSSSSSVAGEQKQEKQEDTKDFPLHSECDAEEDLAQENDHAVEAMYASGSESDAAASFSNEQFLNDVLAQQQDADVHTTDSPDEPDQTAAPQAMQERRETRSTRAKSKAQQAAAAEQPVPAKRRGRSKPEKINRSAEELPKNKRYADYKKSMLEIDEKIAQHMRLTCSICHEGQETFLLLCKHMMQVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCELCDRTFADKQCLRNHELLKHQPDEQKKFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDICERRFPNVSMLCTHVKMVHGNYGTMCDICAQVIRGRAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGSSEECTCSICGKVSPNRSAMLSHQRYVHNADRVHGCSVCNKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKCHPKEFEEARKARMQNRMGDNTSPSKSQTSLITITTGETDGELETHNILVTTTAEHSDGDFKGEDIEFMLTLSPQPAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599815;
90% Identity: iTF_00526815;
80% Identity: -