Dful010625.2
Basic Information
- Insect
- Drosophila fulvimacula
- Gene Symbol
- grau
- Assembly
- GCA_035045555.1
- Location
- JAWNOX010000191.1:9313465-9315925[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 8.6 5.9e+02 1.3 4.0 2 23 283 305 282 306 0.91 2 10 0.026 1.8 9.2 1.1 6 23 314 331 314 331 0.98 3 10 0.00014 0.01 16.3 2.8 1 23 337 360 337 360 0.93 4 10 0.00017 0.012 16.1 2.3 1 23 368 390 368 390 0.97 5 10 0.00023 0.016 15.7 0.5 2 23 396 418 395 418 0.96 6 10 0.16 11 6.8 0.1 2 23 424 445 423 445 0.95 7 10 0.57 39 5.0 4.1 2 23 454 475 453 475 0.91 8 10 0.00011 0.0074 16.7 0.9 2 23 483 505 482 505 0.95 9 10 1.6e-05 0.0011 19.3 0.8 3 23 513 533 512 533 0.99 10 10 0.00016 0.011 16.2 6.3 1 23 539 562 539 562 0.98
Sequence Information
- Coding Sequence
- atgatttgCCGTCTGTGCCTGAACAGCGCCAGCGAcactattcaaatatttgaaggtGTCGGTTTGTCCCTGAACGTTGCCACAGTGCTGGCCAAATATTTCTGGTTCGAGccaaAATGTGATGATCCCATATCGACGGACATCTGCGTGGGCTGTTGGACGCGCGTCAGCgattttaatgagttttacGCAAGTGTGGAGAAGGCGCATCGCCTGCTTACCGAAAGATTCTCAGTCAAAGTAGGtgagcagcaggagagagaggagaggctTAATTCGAGTAGCAACTGTGGCGAACAGAAGCAGGAAGAGCACGATAAGCAAGAGGACACGAAAGATTTTCTCGTCCAGAGCGAATGCGATGCCGACGAGTTTCTGGCAAATGAGGAGCAGCTGCCCACTGTAGAGGCTTTGTATGCGAGTGGAAACGAGAGCGATGCAGGTTCGTTTAGCAATGAGCAGTTTCTTAACGATGTGCTGGCGCAGCAGGGAGAGCCAGAGAGAACTGaagccgatgccgatgccggtGCAGCAGAGCAAGTGCCGAGCACAGAAACTGTGCATCAGGAGCGCCGGGAAACGCGCTCAACCCGCTCCAAGAGCAAGGCCCAGCAAATGAGTgaagctgcaactgctgcagatgcagttgctgctgctgatgctgatgctgtagctgcacttgctgctgctgaggagAAGTCAACGCCTACCAAACGAAGAGGCAGATCGAAAGTCGAAAAGGTCAGCCCCAAACCCGAAGAAGAATTGCCGAAAAACAAACGTTATGTCGACTATAAGAAATCGATGCTAGAGATCGATGAGAAAATAGCTCAGCATATGCGACTCACCTGCAGCATTTGCCACGAGGGCCAGGAGACATTTCTGACGCTCTGCAAGCACATGATGCTGGCGCATCATCGCAAGGGCTATGCCGTCTGCTGCAACAAGAAGTTCTACAAACGTTCCTTTCTCACCGACCACATCGATCGCCACTCGAATCCCGAGAAATTCAAGTGCGAATTGTGCGATCGAACCTTTGCGGACAAGCAATGCTTGCGCAATCACGAGCTGTTGAAGCACCAGCCGGACGAGCAAAAGAAATTCATGTGCGAGCACTGTCCGAAGCGCTATACCAAACAGTATTTATTGGATCAGCATAGGATCATACACAAGGAGCGCAATGTGCCATGCGACATATGCGAGCGGCGTTTCCCCAACATGTCGATGCTGTGCACCCACGTCAAGATGGTGCATGGCAACTATGGCACCATGTGCGACATCTGTGCTCAGGTCATACGTGGACGCGCCGCCTTTCAGCGCCATCAGCTGGAGCATGCTGGCATAACGGAGCCCAAGGTGCAGTGCGACATCTGCGGCTCGTGGCACAAGAACAAATATAGCCTAAAGAAACATGTGCGTCGTCACAATGGCTCCTCCGAGGAATGCACGTGCAATATTTGCGGCAAGGTCTCGCCCAATCGCAGCGCCATGCTCAGCCATCAGCGCTACGTGCACAATGCGGATCGCGTCCATGGCTGCAGCGTGTGCAAAAAGAAGTTCAAAAAGGCCATCAACCTAAAGGAGCACATGGCCACGCACACCGGCGAGGTGCTCTACAAGTGTCCGCATTGCCCCAAGACCTTCAACTCGAATGCGAACAAGCATTCGCATCGCAAGAAGAGCCATCCCAAGGAGTTCGAGGAGGCGCGCAAAGCGCGCATACAAAATCGCATGGGCGCGAACAACAAGAGTCAAACGAGCatgataacaataacaacagacGCCAGCGATGGCCAGCTGGAGACGCACAACATTCTGGTGACAACCAGCTCGGCGCACGACGAGGAGGACTACAAGGGCGAGGATATTGAGTACATGCTCACGCTGAGCCCACAGCCAGCGGAGTAG
- Protein Sequence
- MICRLCLNSASDTIQIFEGVGLSLNVATVLAKYFWFEPKCDDPISTDICVGCWTRVSDFNEFYASVEKAHRLLTERFSVKVGEQQEREERLNSSSNCGEQKQEEHDKQEDTKDFLVQSECDADEFLANEEQLPTVEALYASGNESDAGSFSNEQFLNDVLAQQGEPERTEADADAGAAEQVPSTETVHQERRETRSTRSKSKAQQMSEAATAADAVAAADADAVAALAAAEEKSTPTKRRGRSKVEKVSPKPEEELPKNKRYVDYKKSMLEIDEKIAQHMRLTCSICHEGQETFLTLCKHMMLAHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCELCDRTFADKQCLRNHELLKHQPDEQKKFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDICERRFPNMSMLCTHVKMVHGNYGTMCDICAQVIRGRAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGSSEECTCNICGKVSPNRSAMLSHQRYVHNADRVHGCSVCKKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKSHPKEFEEARKARIQNRMGANNKSQTSMITITTDASDGQLETHNILVTTSSAHDEEDYKGEDIEYMLTLSPQPAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00599815;
- 90% Identity
- -
- 80% Identity
- -