Basic Information

Insect: Drosophila mulleri
Gene Symbol: -
Assembly: GCA_035047565.1
Location: JAWNPK010000060.1:9141519-9143866[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.2 96 3.9 2.5 2 23 275 297 274 298 0.93

2 10 0.024 1.9 9.2 1.1 6 23 306 323 306 323 0.98

3 10 0.00014 0.011 16.3 2.8 1 23 329 352 329 352 0.93

4 10 0.00016 0.012 16.1 2.3 1 23 360 382 360 382 0.97

5 10 0.00021 0.017 15.7 0.5 2 23 388 410 387 410 0.96

6 10 0.14 11 6.8 0.0 2 23 416 437 415 437 0.95

7 10 0.58 45 4.9 4.2 2 23 446 467 445 467 0.91

8 10 0.0001 0.0078 16.7 0.9 2 23 475 497 474 497 0.95

9 10 1.5e-05 0.0012 19.3 0.8 3 23 505 525 504 525 0.99

10 10 0.0011 0.081 13.5 8.9 1 23 531 554 531 554 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.2	96	3.9	2.5	2	23	275	297	274	298	0.93
2	10	0.024	1.9	9.2	1.1	6	23	306	323	306	323	0.98
3	10	0.00014	0.011	16.3	2.8	1	23	329	352	329	352	0.93
4	10	0.00016	0.012	16.1	2.3	1	23	360	382	360	382	0.97
5	10	0.00021	0.017	15.7	0.5	2	23	388	410	387	410	0.96
6	10	0.14	11	6.8	0.0	2	23	416	437	415	437	0.95
7	10	0.58	45	4.9	4.2	2	23	446	467	445	467	0.91
8	10	0.0001	0.0078	16.7	0.9	2	23	475	497	474	497	0.95
9	10	1.5e-05	0.0012	19.3	0.8	3	23	505	525	504	525	0.99
10	10	0.0011	0.081	13.5	8.9	1	23	531	554	531	554	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTGAATAGCGCCAACGacacaattcaaatatttgaaggCGTCGGCTTGTCCTTGAACGTAGCCACAGTGCTGGCCAAGTATTTCTGGTTCGAGCCAAAATGTGATGATCCCATATCGACGGACATCTGCGTGGGCTGCTGGACGCGCGTCAGCgattttaatgagttttacGCACGTGTGGAGAAGGCGCATCGCCTGCTCACCGAAAGGTTCTCAGTTAAGGTGGGCGAGCAGCcggagagagaggagaggctCAATCCACGGAACAACCATGGCGAGCAGAAGCAGGAAGAGCAAGAAAAGCAAGAGGATTCGAAAGATTTTCTCATGCACAGCGAGTGCGCTGCCGATgccgaagccgaagcagaGGAGGATTCGGCAAATGACGAGCAAATGCCCACGGTGGAGGCTTTATATGCGAGTGGAAACGAGAGCGATGCAGCAGCATCGTTTAGCAATGAGCAGTTTCTGAACGATGTGCTGGCCCAGCAGGGAGAGCCAGCTGCCGATGCCAACGCTGATGTGGCCGAAGTGCCGAGCACAGAAATTGCACCTCAAGAGCGTCGGGAGACGCGCTCCACACGCTCCAAGAGCAAAGCCCAACAAGTGACAGaagctgctactgctgcagcttctgctgctgcagcagcggagCAGCCGACGCCTGCGAAACGTCGTGGCCGATCGAAAGTCGAAAAAGTGAGCCCCAATGCCGAAGAGGAATTGCCGAAGAACAAACGCTATGTGGATTATAAGAAATCGATGCTGGAAATTGATGAGAAAATCGCCCAACATATGCGTCTCACCTGCAGCATTTGCAACGAGGGCCAGGAGACATTCCTGACGCTCTGCAAGCACATGATGATGGTGCATCATCGCAAGGGCTATGCCGTCTGCTGCAACAAGAAGTTCTACAAACGTTCCTTTCTCACCGATCACATCGATCGCCACTCGAATCCCGAGAAATTCAAATGCGAATTGTGCGATCGCACCTTTGCGGATAAACAATGTCTGCGCAATCACGAGCTGCTCAAGCACCAGCCGGACgaagaaaagaaattcatgTGCGAGCACTGTCCGAAGCGCTATACGAAGCAGTATTTGTTGGATCAGCATAGGATCATACACAAGGAGCGCAACGTGCCATGCGACATATGCGAGAGGCGTTTCCCCAACATGTCGATGCTGTGCACCCATGTCAAGATGGTTCACGGCAACTATGGCATCATGTGCGACATTTGTGCCCAGGTCATTCGTGGCCGTGCCGCCTTTCAGCGGCATCAGCTGGAGCATGCTGGCATCACGGAGCCGAAGGTGCAGTGCGACATCTGTGGGTCGTGGCACAAGAATAAGTATAGCCTAAAGAAACATGTGCGCCGGCACAATGGCTCCTCCGAGGAATGCACCTGCAACATTTGTGGCAAGGTCTCGCCGAATCGCAGCGCCATGCTCAGCCATCAGCGCTATGTGCACAATGCGGATCGTGTGCATGGCTGCAGCGTCTGCAAGAAGAAATTCAAGAAGGCCATCAATCTGAAGGAGCACATGGCCACGCACACGGGCGAGGTGCTCTACAAGTGTCCGCATTGTCCCAAGACCTTCAACTCGAATGCGAACAAGCATTCGCATCGCAAGAAGTGCCATCCCAAGGAGTTTGAGGAGGCGCGCAAGGCGCGCATACAAAACCGCATGGGCGACAGTAACAAGAGTCAGACGACGAGCATGATAACCATAACAACGGACGCCAGCGATGGCCAGCTGGAGACGCACAACATACTGGTGACAACCACGTCGTCGTCACAGCATGcggacgacgacgaggaggacTACAAGGGCGAGGACATTGAGTACATGCTCACGCTCAGTCCACAGCCAGCGGAGTAG
Protein Sequence: MICRLCLNSANDTIQIFEGVGLSLNVATVLAKYFWFEPKCDDPISTDICVGCWTRVSDFNEFYARVEKAHRLLTERFSVKVGEQPEREERLNPRNNHGEQKQEEQEKQEDSKDFLMHSECAADAEAEAEEDSANDEQMPTVEALYASGNESDAAASFSNEQFLNDVLAQQGEPAADANADVAEVPSTEIAPQERRETRSTRSKSKAQQVTEAATAAASAAAAAEQPTPAKRRGRSKVEKVSPNAEEELPKNKRYVDYKKSMLEIDEKIAQHMRLTCSICNEGQETFLTLCKHMMMVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCELCDRTFADKQCLRNHELLKHQPDEEKKFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDICERRFPNMSMLCTHVKMVHGNYGIMCDICAQVIRGRAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGSSEECTCNICGKVSPNRSAMLSHQRYVHNADRVHGCSVCKKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKCHPKEFEEARKARIQNRMGDSNKSQTTSMITITTDASDGQLETHNILVTTTSSSQHADDDEEDYKGEDIEYMLTLSPQPAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599815;
90% Identity: iTF_00479711;
80% Identity: -