Basic Information

Insect: Drosophila hydei
Gene Symbol: grau
Assembly: GCA_003285905.2
Location: NW:3113510-3116059[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.7 1.5e+02 2.6 4.7 2 23 293 315 292 316 0.94

2 10 0.023 1.3 9.2 1.1 6 23 324 341 324 341 0.98

3 10 0.00013 0.0073 16.3 2.8 1 23 347 370 347 370 0.93

4 10 0.00015 0.0085 16.1 2.3 1 23 378 400 378 400 0.97

5 10 0.0002 0.011 15.7 0.5 2 23 406 428 405 428 0.96

6 10 0.082 4.7 7.4 0.1 2 23 434 455 433 455 0.95

7 10 0.56 32 4.8 4.3 2 23 464 485 463 485 0.91

8 10 9.4e-05 0.0054 16.7 0.9 2 23 493 515 492 515 0.95

9 10 1.4e-05 0.0008 19.3 0.8 3 23 523 543 522 543 0.99

10 10 0.00014 0.008 16.1 6.3 1 23 549 572 549 572 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.7	1.5e+02	2.6	4.7	2	23	293	315	292	316	0.94
2	10	0.023	1.3	9.2	1.1	6	23	324	341	324	341	0.98
3	10	0.00013	0.0073	16.3	2.8	1	23	347	370	347	370	0.93
4	10	0.00015	0.0085	16.1	2.3	1	23	378	400	378	400	0.97
5	10	0.0002	0.011	15.7	0.5	2	23	406	428	405	428	0.96
6	10	0.082	4.7	7.4	0.1	2	23	434	455	433	455	0.95
7	10	0.56	32	4.8	4.3	2	23	464	485	463	485	0.91
8	10	9.4e-05	0.0054	16.7	0.9	2	23	493	515	492	515	0.95
9	10	1.4e-05	0.0008	19.3	0.8	3	23	523	543	522	543	0.99
10	10	0.00014	0.008	16.1	6.3	1	23	549	572	549	572	0.98

Sequence Information

Coding Sequence: atgttttttgttcaCGCATCTAATGGAATAATCAATACAAAAATGATTTGCCGTCTGTGCCTGAACAGCGCCAGCGACaccattcaaatatttgaaggcGTCGGCTTGTCCCTGAACGTTGCCACAGTGCTGGCCAAATATTTCTGGTTCGAGCCGAAATGTGATGATCCCATATCGACGGACATCTGCGTGGGCTGTTGGAAGCGCGTCAGCGATTTTAATGAGTTCTACGCAAGTGTGGAGAAGGCGCATCGCCTGCTCACCGAAAGATTCTCAGTCAAAGTAGCCGAGCAGCAGGAGAGAGAGGAACGGCTTCTTAGCAGAAGCAACACTGACCAGCAGAAGCAGGAAGAGCAAGAAAAGGAGGATTCGAGAGATTTTCTCATGCACAGCGAATGCGGTGCCGAGGAGGATTTGACAAATGAAGAGCATAAGCCCACAGTGGAGGCTTTGTATGCGAGTGGAAATGAGAGCGATGCAGCGGCATCGTTTAGCAATGAGCAGTTTCTCAACGATGTGCTGGCCCAGCAGGTAGAGCCAGATGTTgatgctgacgctgacgctgttgctgatgctgatggtaCCGCAGACGAACAAGTGCCGAACACTGAGACTGTGAAGCAGGAACGCCGAGAAACGCGCTCAACACGCTCCAAGAGCAAAGCTCAGCAAGTGACAgaagcaacaactgctgcagctgttgctgcggcgACTGCTGCAGCGGAGCAGTCAACGCCGACCAAACGTCGAGGCAGATCGAAAGCCGAAAAAGTTAGCCCCAATGCTGAAGAAGAATTGCCGAAGAACAAACGCTATGTCGACTATAAGAAATCGATGTTAGAGATCGATGAGAAAATAGCACAACATATGCGACTCACCTGCAGCATTTGCCACGAGGGACAGGAGACATTTCTGACGCTCTGCAAGCATATGATGACGGTGCATCATCGCAAGGGCTATGCGGTCTGCTGCAACAAGAAGTTCTATAAACGTTCCTTCCTCACCGACCACATCGATCGGCACTCGAATCCCGAGAAATTCAAGTGCGAATTGTGCGATCGAACCTTTGCGGACAAGCAATGTTTGCGCAATCATGAGCTGTTGAAGCATCAGCCGGACGAGCAAAAGAAATTCATGTGCGAACACTGTCCCAAGCGCTATACCAAGCAGTATTTACTCGACCAGCACAGGATCATACACAAGGAGCGCAATGTGCCCTGCGACATATGCGAGCGGCGTTTCCCCAACATGTCGATGCTGTGCACTCACGTGAAGATGGTGCATGGCAATTATGGCACCATGTGCGACATTTGTGCCCAGGTCATACGAGGACAAGCCGCCTTTAAGCGCCATCAGCTGGAGCATGCTGGCATTACGGAGCCGAAGGTGCAGTGCGACATTTGTGGCTCGTGGCATAAGAACAAATATAGTTTAAAGAAGCACGTGCGTCGTCATAACGGCTCGTCCGAGGAGTGCACGTGCAACATTTGCGGCAAGGTGTCGCCCAACCGCAGCGCCATGCTCAGCCATCAGCGTTACGTGCACAACGCAGATCGCGTGCATGGCTGCAGCGTGTGCAAAAAGAAGTTCAAAAAGGCCATCAACCTCAAGGAGCACATGGCCACACACACGGGTGAGGTGCTCTACAAGTGCCCGCATTGCCCCAAGACCTTCAATTCGAATGCGAACAAGCATTCGCATCGCAAGAAGAGCCATCCCAAGGAGTTTGAAGAGGCGCGCAAGGCGCGCATACAAAATCGCATGGGCGACAATAACAAGAGTCAAACGACAAGCatgataacaataacaacagacGCCAGCGATGGCCAGCTGGAGACGCACAATATACTGGTCACAACAACCTCGGCACAGCATCCggatgacgacgacgaggatTACAAAGGCGAAGACATTGAGTACATGCTCACGCTCAGTCCACAGCCAGCGGAGTAG
Protein Sequence: MFFVHASNGIINTKMICRLCLNSASDTIQIFEGVGLSLNVATVLAKYFWFEPKCDDPISTDICVGCWKRVSDFNEFYASVEKAHRLLTERFSVKVAEQQEREERLLSRSNTDQQKQEEQEKEDSRDFLMHSECGAEEDLTNEEHKPTVEALYASGNESDAAASFSNEQFLNDVLAQQVEPDVDADADAVADADGTADEQVPNTETVKQERRETRSTRSKSKAQQVTEATTAAAVAAATAAAEQSTPTKRRGRSKAEKVSPNAEEELPKNKRYVDYKKSMLEIDEKIAQHMRLTCSICHEGQETFLTLCKHMMTVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCELCDRTFADKQCLRNHELLKHQPDEQKKFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDICERRFPNMSMLCTHVKMVHGNYGTMCDICAQVIRGQAAFKRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGSSEECTCNICGKVSPNRSAMLSHQRYVHNADRVHGCSVCKKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKSHPKEFEEARKARIQNRMGDNNKSQTTSMITITTDASDGQLETHNILVTTTSAQHPDDDDEDYKGEDIEYMLTLSPQPAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599815;
90% Identity: iTF_00502750;
80% Identity: -