Basic Information

Insect: Drosophila novamexicana
Gene Symbol: grau
Assembly: GCA_003285875.3
Location: NW:5038170-5040447[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 9.4 5e+02 1.0 4.1 2 23 258 280 257 281 0.91

2 10 0.022 1.2 9.3 1.1 6 23 289 306 289 306 0.98

3 10 0.00013 0.0067 16.4 2.8 1 23 312 335 312 335 0.93

4 10 0.00015 0.0079 16.1 2.3 1 23 343 365 343 365 0.97

5 10 0.00023 0.012 15.6 0.3 2 23 371 393 370 393 0.96

6 10 0.14 7.3 6.8 0.1 2 23 399 420 398 420 0.95

7 10 0.6 32 4.8 4.4 2 23 429 450 428 450 0.91

8 10 0.00014 0.0073 16.3 0.9 2 23 458 480 457 480 0.95

9 10 8e-06 0.00043 20.1 0.6 3 23 488 508 487 508 0.99

10 10 0.00097 0.052 13.6 8.9 1 23 514 537 514 537 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	9.4	5e+02	1.0	4.1	2	23	258	280	257	281	0.91
2	10	0.022	1.2	9.3	1.1	6	23	289	306	289	306	0.98
3	10	0.00013	0.0067	16.4	2.8	1	23	312	335	312	335	0.93
4	10	0.00015	0.0079	16.1	2.3	1	23	343	365	343	365	0.97
5	10	0.00023	0.012	15.6	0.3	2	23	371	393	370	393	0.96
6	10	0.14	7.3	6.8	0.1	2	23	399	420	398	420	0.95
7	10	0.6	32	4.8	4.4	2	23	429	450	428	450	0.91
8	10	0.00014	0.0073	16.3	0.9	2	23	458	480	457	480	0.95
9	10	8e-06	0.00043	20.1	0.6	3	23	488	508	487	508	0.99
10	10	0.00097	0.052	13.6	8.9	1	23	514	537	514	537	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTGAACAGCGCAAGCGACAccattcaaatatttgagGGCGTCGGCTTGTCCCTGAACGTAGCAACAGTGCTGGCCAAGTATTTCTGGTTTCAgCCGAAAAGCGATGATCCCATATCGACGGACATTTGTGTGGGCTGCTGGGCGCGTGTCAGCGACTTTAACGAGTTCTATGCCAGCGTGGAAAAAGCGCATCGTCTGCTCACCGAGAGATTCTCTATCAAAGGCGGCGAACAGCCGGAGCGGATTActacaagcagcagcagttcggTAGCAGGCGAGCAGAAGCAGGAAAAGCAGGAGGACACAAAAGACTTTCCTCTGCACAGCGAATGCGACGCCGAGGAAGACTTGGCTCAGGAGAACGACCATGCTGTGGAGGCAATGTACGCCAGCGGCAGCGAGAGCGATGCAGCTGCATCATTCAGCAACGAGCAGTTCCTCAACGATGTGCTGGCCCAGCAGCAAGATGCTGATGTGCATGCAACAGACTCGCCCGATATGCCGGACCAAGCCGCGGCACCAGGAGCTGTGCAAGAGCGTCGTGAAACGCGCTCAACGCGCGCCAAAAGCAAAGCCCAACAAGCTGCTGAgactgctgcagctgagcaGCCTGTGTCGGCCAAGCGCCGAGGTAGGTCGAAGCCCGAGAAAATCAACCCAAGCGCCGAGGAATTGCCAAAGAACAAACGCTATGCAGATTACAAGAAATCCATGCTGGAGATCGATGAAAAGATAGCGCAACATATGCGGCTCACCTGCAGCATTTGCCACGAGGGACAGGAGACGTTTCTGCTGCTCTGCAAGCACATGATGCAGGTGCACCATCGCAAGGGCTATGCGGTGTGCTGCAACAAGAAGTTCTACAAACGTTCCTTTCTCACAGATCACATTGATCGCCACTCGAACCCCGAGAAATTTAAGTGCGAGCTCTGCGACAGAACCTTTGCAGACAAACAGTGCCTGCGCAATCATGAGCTGCTCAAGCATCAGCCGGACGAGCAGAAGAAGTTCATGTGCGAGCATTGTCCCAAGCGCTATACAAAGCAGTATTTATTGGATCAGCATAGAATTATACACAAGGAGCGCAACGTGCCTTGCGATATATGCGAGCGGCGATTTCCCAACGTTTCAATGCTCTGCACGCACGTCAAGATGGTGCACGGCAACTATGGCACCATGTGCGACATATGTGCCCAGGTGATACGAGGACGCGCTGCTTTTCAGCGCCATCAGCTGGAGCATGCTGGCATTACGGAGCCCAAGGTGCAGTGCGACATATGCGGCTCGTGGCACAAGAACAAATATAGTCTAAAGAAGCATGTGCGACGGCACAACGGCTCCTCCGAGGAGTGCACCTGCAGCATATGCGGCAAGGTGTCGCCCAACCGCAGCGCCATGCTCAGCCACCAGCGCTATGTGCACAACGCGGATCGGGTCCATGGCTGCAGTGTGTGCAATAAGAAGTTCAAAAAGGCCATCAATCTCAAGGAGCACATGGCCACGCACACCGGCGAGGTGCTCTACAAGTGTCCGCACTGTCCGAAAACCTTCAATTCGAATGCCAACAAGCATTCGCATCGAAAAAAGTGCCATCCCAAGGAGTTCGAGGAGGCGCGCAAGGCCCGCATGCAAAATCGCATGGGCGACAACACAAGCCCAAGCAAATCTCAAACGAGCCTGATAACCATTACCACGGGCGAGACCGACGGCGAGCTGGAGACGCACAATATACTCGTAACCACGACGGCGGAGCACAGCGATGGTGATTTCAAGGGCGAGGACATTGAGTTCATGCTCACACTCAGTCCACAGCCGGCGGAATAG
Protein Sequence: MICRLCLNSASDTIQIFEGVGLSLNVATVLAKYFWFQPKSDDPISTDICVGCWARVSDFNEFYASVEKAHRLLTERFSIKGGEQPERITTSSSSSVAGEQKQEKQEDTKDFPLHSECDAEEDLAQENDHAVEAMYASGSESDAAASFSNEQFLNDVLAQQQDADVHATDSPDMPDQAAAPGAVQERRETRSTRAKSKAQQAAETAAAEQPVSAKRRGRSKPEKINPSAEELPKNKRYADYKKSMLEIDEKIAQHMRLTCSICHEGQETFLLLCKHMMQVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCELCDRTFADKQCLRNHELLKHQPDEQKKFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDICERRFPNVSMLCTHVKMVHGNYGTMCDICAQVIRGRAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVRRHNGSSEECTCSICGKVSPNRSAMLSHQRYVHNADRVHGCSVCNKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKCHPKEFEEARKARMQNRMGDNTSPSKSQTSLITITTGETDGELETHNILVTTTAEHSDGDFKGEDIEFMLTLSPQPAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599815;
90% Identity: iTF_00526815;
80% Identity: -