Dpha022409.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila phalerata
Gene Symbol
-
Assembly
GCA_951394115.2
Location
OY729850.1:18505624-18513839[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00025 0.025 15.6 3.4 1 23 302 324 302 324 0.98
2 11 0.0012 0.12 13.4 10.5 1 23 331 353 331 353 0.96
3 11 0.00012 0.012 16.5 6.5 1 23 359 381 359 381 0.98
4 11 0.00038 0.037 15.0 2.3 1 23 387 409 387 409 0.95
5 11 2.7e-05 0.0027 18.6 0.5 1 23 415 437 415 437 0.97
6 11 1.8e-05 0.0018 19.2 0.1 1 23 443 465 443 465 0.98
7 11 0.00015 0.015 16.3 2.0 1 23 470 493 470 493 0.97
8 11 0.064 6.3 8.0 0.3 1 23 499 522 499 522 0.94
9 11 0.0002 0.02 15.8 0.1 1 23 581 603 581 603 0.98
10 11 0.019 1.8 9.7 2.7 1 23 717 739 717 739 0.95
11 11 0.0054 0.54 11.4 4.9 5 23 752 770 744 770 0.92

Sequence Information

Coding Sequence
ATGTGCGCTGCACAGAGCAATCCGCCCTTCGGCTACGCTTGGAGTTTTGCAGACAACGGCAACCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACTGTCGGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAAGGTGCACTCACTGCCAGCAATAAAGGCAATCTCGTCCGTCGTATGTTCGTGGTGAACGACACATTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCTCCGCATCGACGGTGGTCAAAAAACAGGACTCTGGTCAACAGGTGTTGAGCATAAATTCGCTCGATAAGAACTATCTATTAGTCGATccagcgacagcggcagcggctgCGGCTGCAGCAGCAGGTGGTGATCCAGCGTCAGCTGCACATCATCAGCATACATTGACAAATGGCAGCATTGTTGATGCCAAAACCGGACAAACTGTATTGACATCGAGCGCTGCAGCGGCTAAGTCGCATTTTAACTCAATTGGTGCACTGCATCTCACGCAAGAGGAGTGCAATGAGATTCTAATTAAGCGCGCCATTGCAGCCGGCCACGGTCACGGTCACAGTCACCATCagacgcacacgcacacactcaccGCTGCTGGCGACGGAtcgcaccaccaccaccaccaccatcaTTCGACGGCGCCAGGCGCAACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCACAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAaCCGACGCCACCATCAAGAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGTAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGTGGTGAACGTCCACATATTTGCACCCATTGCGGCAAGAGTTTTGCGCACAAACATTGTCTAAATACGCATCTACTGTTGCACTCCACCGATCGGCCATATCAGTGTCAGGAGTGTAAAAAGAGTTTTACCCTTAAGCATCATCTGTTGACGCATTCACGTGTCCATAGCCGGGAACGGCCATTTGTTTGCCAGGAGTGCGGACGATCCTTTCCCCTCAAACGTCACTTGGTGACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAAAGTTTCGCACAGGAGAATCACCTTATTATGCATTCGCGCTTTCATGGTTCATTGAATCCATTTGTCTGTGCTGATTGCGGTGCATCATTTCCACGCAAGTTTCAACTGGTTAATCACGGACGTATTCACGGCAAAATTCCTCACTCCTGTACGGTTTGTGGCAAGGAATTTTTACAGAAGCGCACACTAGTTTCCCACATGAGGCGCGTACATACCGGAGAGCAGGCGCATCCCTGCGTGAGCTGCGGCGAGGGATTCCTCACCAAGGCGGAGCTGCATCAACATGTGCGTGCAGCGCACAATGGTGTCAATCCCAATACGAGCAGTGCCACCATTATAGCCAATCAACAGcagATACAACAGGCACATCATCACCCCGGACATCCGCAGACCATAACCGTTGTCAGTAATCCATCAAACTCCACGCTGCTCACCGTCTCCACAACCGATGCCAATGGTGTGGCACGTCCACAATTTGTTTGCCGTGAGTGTGGAAGCGCGTTTAATAGCCGGGAGGCGCTTGCCTTGCACTTGAGATTGCACACGGGCGACAAGAGTCTGATGACAGATCTGTGCGCTTTGACAGCCGCGCTGCCTGGTCACTTCTTGAGCACGGCCAGCCTCAATCCGGGCACGGTGGTCACGGCCAATCCGAATCTGGTGGGCCAGAGTCCAGTGCCCGTGCAAATCATATCGTCCACCGGTCAGGTGATGTCACAGACAACGCTGGTGCAGGCCGCCAACTCGACCCATCCGCAAGCCGTTGTCACCGCTGTGCCCACGATGCCCCTCCACGGCCAACAGCATCTACAGCATGTggcccagcagcagcagcagcaacaacatgtgGTCACCGTATCGCCGGCCAATAAACCCAAATCGCATTTCTGCGCCAGCTGTGGCAAAGGATTCGCTGCCAAGCACGGACTAATGCAGCACAATCGGCGACATCCGAACGGCGGCTGCACGGTGCGCACTCATGTCTGCGAGTGTGGAAAGGCATTCTTCCAAAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACAAAGCCAGCCATATCGCAGCAACAGGATGCCGatgtgcagcagcaacaacagcaacaacaacaacaagcagcagctgctgcagcggCAGCCGGACAACAAACGGGACAAATTGAAGTGCAAATAGTACCCGGTGGACCTGGCAAGGTGATCAAATATGAAATCTGTCGCAATGTCCTGCAGGATGAACAGTcagcacagcagcagcagcagggaTCAATGCATGCGGAATAG
Protein Sequence
MCAAQSNPPFGYAWSFADNGNRAAESVLEISPNINYTVGGESMPYLLSTDGSLAVQKDVKGALTASNKGNLVRRMFVVNDTFAPGTQRVITTGSASTVVKKQDSGQQVLSINSLDKNYLLVDPATAAAAAAAAAGGDPASAAHHQHTLTNGSIVDAKTGQTVLTSSAAAAKSHFNSIGALHLTQEECNEILIKRAIAAGHGHGHSHHQTHTHTLTAAGDGSHHHHHHHHSTAPGATPSDILPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCADCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQIQQAHHHPGHPQTITVVSNPSNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPLHGQQHLQHVAQQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQDADVQQQQQQQQQQAAAAAAAAGQQTGQIEVQIVPGGPGKVIKYEICRNVLQDEQSAQQQQQGSMHAE