Dmer016364.2
Basic Information
- Insect
- Drosophila meridiana
- Gene Symbol
- -
- Assembly
- GCA_035045185.1
- Location
- JAWNPF010000171.1:14778134-14786371[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00025 0.019 15.6 3.4 1 23 294 316 294 316 0.98 2 11 0.0012 0.093 13.4 10.5 1 23 323 345 323 345 0.96 3 11 0.00012 0.0093 16.5 6.5 1 23 351 373 351 373 0.98 4 11 0.00056 0.042 14.5 1.6 1 23 379 401 379 401 0.95 5 11 2.7e-05 0.002 18.6 0.5 1 23 407 429 407 429 0.97 6 11 1.8e-05 0.0013 19.2 0.1 1 23 435 457 435 457 0.98 7 11 0.00015 0.011 16.3 2.0 1 23 462 485 462 485 0.97 8 11 0.063 4.8 8.0 0.3 1 23 491 514 491 514 0.94 9 11 0.0002 0.015 15.9 0.1 1 23 573 595 573 595 0.98 10 11 0.018 1.4 9.7 2.7 1 23 707 729 707 729 0.95 11 11 0.0054 0.41 11.4 4.9 5 23 742 760 734 760 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCTGCACAGAGCAATCCGCCGCCCTTCGGCTATACTTGGGGTTTTGCAGACGGCAACCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACCGTCAGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAAGGTGCACTCGCCAGCAATAAGGGCAATGTCGTTCGTCGCATGTTCGTGGTGAACGATTCCTCGTTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCGCCGCCTCGACGGTGGTCAAAAAACAGGACTCTGGTCAACAGGTGTTGAGCATAAATTCGCTCGATAAGAACTATCTTTTGGTTGATCaggcaacagcggcagcagctgcggctgcggcagcagGTGGAGGTGATCCGGCGAATGCTGCGCACCATCATGCACTGACTAATGGCAGCATTGTTGACACAAAAACTGGACAAACGGTATTAACCACATCGAGTGCCGCCGCTGCGGCCAAGTCGCATTTTGGCTCAATTGGAGCATTGCATCTCACCCAAGAGGAGTGCAATGAGATCCTAATCAAGCGCGCCATTGCAGCCGGCCACGGCCACCACcagacgcacacactcacCGCTGGCGACGGAGCCCACCACCATCATCATTCGACGGCGCCAGGCGCGACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAAAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGTAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGTGGCGAACGACCACATATTTGCACCCATTGCGGCAAAAGTTTTGCGCACAAACACTGTCTAAATACGCATCTGCTGCTTCACTCAACTGATCGGCCATATCAGTGTCAGGAGTGCAAGAAGAGCTTTACGCTTAAGCATCATCTATTGACGCATTCGCGCGTCCACAGCCGGGAACGGCCATTTGTTTGCCAGGAGTGCGGACGTGCATTTCCCCTCAAACGTCATCTGGTGACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAAAGTTTCGCACAGGAGAATCACCTGATTATGCACTCGCGCTTTCATGGTTCATTGAATCCATTTGTTTGCGCTGATTGCGGAGCCTCGTTTCCACGAAAGTTTCAATTGGTTAACCACGGTCGCATCCACGGCAAGATACCACACTCCTGCACAGTTTGTGGCAAAGAATTTCTACAGAAGCGCACACTAGTTTCCCACATGAGGCGCGTACATACCGGCGAGCAGGCGCATCCCTGCGTTAGCTGCGGCGAAGGTTTCCTCACCAAAGCAGAGCTGCACCAACATGTGCGTGCAGCGCACAATGGCGTCAATCCCAATACGAGCAGCGCCACCATAATAGCCAATCAACAGCAGCTTCAACAGCCGCATCATCATCCCGGACATCCACAGACGATCACCGTTGTCAGCAATCCAGCTAATTCGACGTTGCTCACCGTCTCCACAACCGATGCGAATGGTGTCACGCGCCCACAGTTCGTTTGCCGTGAATGCGGCAGCGCGTTTAATAGCCGTGAGGCGCTCGCCTTGCACTTGCGACTGCATACAGGCGACAAGAGCTTGATGACCGATCTGTGCGCCTTGACAGCAGCGCTGCCTGGTCACTTCTTGAGCACGGCGAGCCTCAATCCTGGCACTGTGGTCACGGCCAATCCAAATCTGGTGGGACAGAGTCCGGTGCCGGTGCAAATCATATCATCCACCGGTCAGGTGATGTCACAGACCACGCTGGTGCAGGCCGCCAACTCGACCCATCCGCAAGCCGTTGTCACAGCCGTGCCCACAATGCCCGTCCACGGGCAACAGCATCTGCAGCAcgtccagcaacagcagcagcagcatgtggTCACCGTGTCACCGGCCAACAAGCCTAAATCGCATTTCTGCGCCAGCTGCGGCAAAGGATTCGCCGCCAAGCACGGCCTAATGCAGCACAATCGACGACATCCAAACGGCGGCTGCACGGTTCGCACCCATGTCTGCGAATGTGGAAAGGCGTTCTTCCAAAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACAAAGCCAGCCATATCGCAGCAACAGGAGGCcgaagtgcagcagcagcaacaagcacaGGCACAagctgcagccgccgccgcagcgggCCAACAACCTGCTCAGGTGGAGGTGCAAATCGTGTCCAGTGGCCACGGCCATGGCAAGGTCATCAAATACGAGATCTGTCGCAATGTActgcaggaggagcagcaacagcagcagcagcaacaacagaactCCATGCATGCAGAGTAA
- Protein Sequence
- MCAAQSNPPPFGYTWGFADGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALASNKGNVVRRMFVVNDSSFAPGTQRVITTGAASTVVKKQDSGQQVLSINSLDKNYLLVDQATAAAAAAAAAGGGDPANAAHHHALTNGSIVDTKTGQTVLTTSSAAAAAKSHFGSIGALHLTQEECNEILIKRAIAAGHGHHQTHTLTAGDGAHHHHHSTAPGATPSDILPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCADCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQLQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVTRPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQHLQHVQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEAEVQQQQQAQAQAAAAAAAGQQPAQVEVQIVSSGHGHGKVIKYEICRNVLQEEQQQQQQQQQNSMHAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575764;
- 90% Identity
- iTF_00803779;
- 80% Identity
- iTF_00545401;