Dgla005467.3
Basic Information
- Insect
- Drosophila glabriapex
- Gene Symbol
- -
- Assembly
- GCA_035042305.1
- Location
- JAWNLN010000046.1:18970071-18978808[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00025 0.016 15.5 3.4 1 23 310 332 310 332 0.98 2 11 0.0012 0.078 13.4 10.5 1 23 339 361 339 361 0.96 3 11 0.00013 0.0078 16.5 6.5 1 23 367 389 367 389 0.98 4 11 0.00038 0.024 15.0 2.3 1 23 395 417 395 417 0.95 5 11 2.7e-05 0.0017 18.6 0.5 1 23 423 445 423 445 0.97 6 11 2.4e-06 0.00015 21.9 0.1 1 23 451 473 451 473 0.98 7 11 0.00015 0.0096 16.2 2.0 1 23 478 501 478 501 0.97 8 11 0.064 4 8.0 0.3 1 23 507 530 507 530 0.94 9 11 0.00021 0.013 15.8 0.1 1 23 589 611 589 611 0.98 10 11 0.019 1.2 9.7 2.7 1 23 725 747 725 747 0.95 11 11 0.0055 0.34 11.3 4.9 5 23 760 778 752 778 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCTGCACAGAGCAATCCGCCGCCCTTCGGCTACACTTGGGGTTTTGCAGACAACGGCAACCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACTGTCAGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAGGGCGCACTCTCCAGCAATAAGGGCAATGTCGTTCGTCGCATGTTCGTCGTGAACGATTCCTCATTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCTCCGCATCGACGGTGGTCAAAAAACAGGACTCTGGTCAGCAGGTGTTGAGCATAAATTCGCTCGATAAGAATTATCTTTTGGTCGATcaggcaacagcggcagcagctgcagctgcagcagcagcgggcgGAGGAGGTGAtccggcagcggcggcggcccaccaccaccatcatcatcatacaTTGACAAATGGTGGCAGCATTGTTGATGCCAAAACTGGACAAACCGTATTGAcatcggcggcggcggcggcagcggcgagcgctgcagcagccaaatcGCATTTTAGCTCTATTGGTGCACTGCATCTTACCCAAGAGGAGTGCAATGAGATACTAATTAAGCGCGCCATTGCAGCCGGCCAcggccatcatcatcagacGCACCCAACAGCAATCACCAACGCTGGCGACGGAGCGCACCATCATCATTCGGCGCCAGGCGCGACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAAAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGCAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGgtgGTGAACGACCCCATATTTGCACACATTGCGGCAAGAGTTTTGCGCACAAACACTGTCTGAATACGCATCTGCTGTTGCATTCAACGGATCGGCCATATCAGTGTCAGGAGTGCAAGAAGAGTTTCACACTCAAGCATCATCTGTTGACGCATTCCCGGGTCCACAGCCGGGAGCGACCATTCGTTTGCCAGGAGTGCGGACGATCCTTTCCCCTCAAACGGCATCTGGTCACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAGAGTTTCGCACAGGAGAACCATCTGATTATGCACTCGCGctttCATGGTTCATTGAATCCATTTGTTTGTCCTGATTGCGGTGCCTCGTTTCCAcgaaaatttcaattggttAATCACGGACGCATACACGGCAAGATACCACACTCCTGCACCGTTTGCGGCAAAGAGTTTCTACAGAAGCGCACACTAGTTTCCCACATGAGGCGCGTACATACCGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAAGGTTTCCTCACCAAGGCGGAACTGCATCAGCATGTGCGTGCGGCGCACAATGGCGTCAATCCCAATACGAGCAGCGCCACCATTATAGCCAATCAACAGcAGATACAACAGCCGCATCATCATCCGGGACATCCGCAGACCATAACCGTTGTCAGCAATCCGGCTAATTCAACGCTGCTCACCGTCTCCACAACCGATGCGAATGGCGTGGCGCGTCCACAATTCGTTTGCCGTGAATGCGGCAGCGCGTTTAATAGTCGGGAAGCGCTCGCCTTGCACTTGCGACTGCACACCGGCGACAAGAGTCTGATGACCGATTTGTGTGCGCTGACAGCGGCGCTGCCGGGACACTTTTTGAGTACGGCCAGCTTAAATCCGGGCACTGTGGTTACGGCCAATCCGAATATGGTTGGGCAGAGTCCGGTGCCGGTGCAAATCATATCATCGACCGGTCAGGTGATGTCGCAGACCACACTGGTGCAGGCCGCCAATTCAACGCATCCGCAAGCTGTGGTCACCGCCGTGCCCACAATGCCCCTCCACGGGCAACACCATCTGCAGCacatccagcagcagcagcagcagcaacaacatgtcGTCACCGTCTCACCGGCCAACAAACCCAAATCGCATTTCTGCGCCAGCTGCGGCAAGGGATTCGCTGCGAAGCACGGCCTAATGCAACACAATCGCAGGCATCCGAATGGCGGCTGCACGGTGCGCACCCATGTCTGCGAGTGTGGAAAGGCGTTCTTCCAAAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACGAAGCCAGCCATATCGCAGCAACAGGAGGCCgacgtgcaacagcagcagcagcaacaacaacaagcagcagctgcggctgctgctgcagccgctggACAACAATCCACACAGGTGGAGGTGCAAATATTGCCCGGTGGCCATGCCAAGGTCATCAAGTATGAGATCTGTCGAAATGTCCTGCAGGAGGAGCAATccgcccaacagcagcagcagcaacaacaacaacagcagcagcagcaggcatcaATGCATGCGGAATAG
- Protein Sequence
- MCAAQSNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALSSNKGNVVRRMFVVNDSSFAPGTQRVITTGSASTVVKKQDSGQQVLSINSLDKNYLLVDQATAAAAAAAAAAGGGGDPAAAAAHHHHHHHTLTNGGSIVDAKTGQTVLTSAAAAAAASAAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHGHHHQTHPTAITNAGDGAHHHHSAPGATPSDILPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCPDCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQIQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNMVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPLHGQHHLQHIQQQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEADVQQQQQQQQQAAAAAAAAAAGQQSTQVEVQILPGGHAKVIKYEICRNVLQEEQSAQQQQQQQQQQQQQQASMHAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575764;
- 90% Identity
- iTF_00803779;
- 80% Identity
- -