Dfun003374.1
Basic Information
- Insect
- Drosophila funebris
- Gene Symbol
- -
- Assembly
- GCA_018901825.1
- Location
- JAEIFK010000682.1:5132229-5140385[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00023 0.016 15.6 3.4 1 23 291 313 291 313 0.98 2 11 0.0011 0.076 13.4 10.5 1 23 320 342 320 342 0.96 3 11 0.00011 0.0077 16.5 6.5 1 23 348 370 348 370 0.98 4 11 0.00034 0.023 15.0 2.3 1 23 376 398 376 398 0.95 5 11 2.4e-05 0.0017 18.6 0.5 1 23 404 426 404 426 0.97 6 11 1.6e-05 0.0011 19.2 0.1 1 23 432 454 432 454 0.98 7 11 0.00014 0.0094 16.3 2.0 1 23 459 482 459 482 0.97 8 11 0.058 3.9 8.0 0.3 1 23 488 511 488 511 0.94 9 11 0.00019 0.013 15.9 0.1 1 23 570 592 570 592 0.98 10 11 0.017 1.1 9.7 2.7 1 23 705 727 705 727 0.95 11 11 0.0049 0.33 11.4 4.9 5 23 740 758 732 758 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCTGCACAGAGCAATCCGCCCTTCGGCTACGCTTGGAGTTTTGCAGACAACGGCAACCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACTGTCGGTGGGGAATCGATGCCCTATCTGTTATCCTCGGATGGATCATTGGCCGTACAAAAGGATGTTAAAGGTGCACTCGCTGCTGCCAGCAATAAGGGCAATGTCGTCCGTCGTATGTTCGTGGTGAACGATTCATTTGCGCCCGGATCACAAAGAGTAATTACCACAGGCGCCGCATCGACGGTGGTCAAAAAACAGGACTCCGGTCAACAGGTGTTGAGCATAAATTCGCTCGATAAGAACTATCTATTAGTCGATCCAGCGACAGCGGCAGCAGCTGCAGCTGCAGCAGCAGGTGGTGATCCAGCGGCTGCTGCACATCATCATACATTAACAAATGGCAACATTGTTGACGCCAAAACTGGACAAACTGTATTGACATCGAGCGCCGCTGCGGCAAAGTCGCATTTTAGCTCAATTGGTGCACTGCATCTCACACAAGAGGAGTGCAATGAGATCTTAATCAAGCGCGCCATTGCAGCCGGCCACGGCCACCATCAGACGCACACAATCACAGCTGGCGACGGAGCGCACCACCATCATTCGTCGGGGCCAGGCGCGACACCAAGTGACATACTTCCTGGTATTTCAGTTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCACAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACTTTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAGAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGTAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGTGGCGAACGTCCACACATTTGCACCCATTGCGGCAAGAGCTTTGCGCACAAACATTGTCTAAATACGCATCTACTGCTGCACTCCACCGATCGGCCATATCAGTGTCAAGAGTGTAAGAAGAGTTTTACCCTTAAGCATCATCTGTTGACGCATTCGCGTGTCCATAGCCGGGAACGGCCATTCGTGTGCCAGGAGTGCGGACGATCGTTTCCCCTCAAACGTCATCTGGTGACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAAAGTTTCGCACAGGAGAACCATCTGATTATGCACTCGCGCTTTCACGGGTCACTGAATCCATTTGTCTGTGCTGATTGCGGTGCATCATTTCCACGCAAGTTTCAATTGGTTAATCACGGTCGCATCCACGGCAAAATACCCCACTCCTGTACGGTTTGTGGCAAAGAATTTCTACAGAAGCGCACGCTAGTTTCCCATATGAGGCGTGTACATACCGGAGAGCAGGCGCATCCCTGCGTTAGCTGCGGCGAGGGATTCCTCACCAAAGCGGAGCTGCATCAACATGTGCGTGCGGCGCACAATGGTGTCAATCCCAATACGAGCAGTGCCACCATTATAGCCAATCAACAGCAGATACAACAGCCACATCATCACCCCGGTCATCCGCAGACCATTACCGTTGTCAGTAATCCAGCAAACTCCACGCTGCTCACCGTCTCCACAACGGATGCCAATGGCGTGGCACGTCCACAATTTGTTTGCCGCGAATGTGGAAGCGCGTTTAATAGCCGTGAGGCGCTTGCCCTGCACTTGCGATTGCACACGGGAGACAAGAGTCTTATGACAGATCTGTGCGCATTGACAGCAGCGCTGCCGGGTCACTTTTTGAGCACGGCAAGCCTCAATCCAGGCACCGTGGTTACGGCCAATCCGAATCTGGTGGGACAAAGTCCAGTGCCTGTGCAAATCATATCGTCCACCGGTCAGGTGATGTCACAGACCACACTGGTGCAGGCCGCCAACTCGACACATCCGCAAGCCGTTGTCACCGCTGTGCCCACGATGCCCATACACGGCCAACAGCATCTGCAGCATGTGCAGCAACAGCAGCAGCAACAGCATGTGGTCACCGTATCTCCGGCCAATAAGCCCAAATCGCATTTCTGCGCCAGCTGTGGCAAAGGATTCGCTGCCAAGCACGGTTTAATGCAGCACAATCGACGACATCCAAACGGCGGCTGCACGGTGCGCACCCATGTCTGCGAGTGTGGAAAGGCATTCTTCCAAAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACAAAGCCAGCCATATCGCAGCAACAGGAGGCCGATGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTGCACAGATTGAGGTGCAAATAGTACCCGGTGGGCCCGGCAAGGTGATTAAATATGAAATCTGTCGCAATGTCCTGCAGGATGAACAGTCGGCACAGCAGCAACAGGGATCAATGCACACGGAATAG
- Protein Sequence
- MCAAQSNPPFGYAWSFADNGNRAAESVLEISPNINYTVGGESMPYLLSSDGSLAVQKDVKGALAAASNKGNVVRRMFVVNDSFAPGSQRVITTGAASTVVKKQDSGQQVLSINSLDKNYLLVDPATAAAAAAAAAGGDPAAAAHHHTLTNGNIVDAKTGQTVLTSSAAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHGHHQTHTITAGDGAHHHHSSGPGATPSDILPGISVQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCADCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQQIQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPIHGQQHLQHVQQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEADVXXXXXXXXXXXXXXXXXXXXXXXXXAQIEVQIVPGGPGKVIKYEICRNVLQDEQSAQQQQGSMHTE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575764;
- 90% Identity
- iTF_00803779;
- 80% Identity
- -