Dneo005532.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila neotestacea
Gene Symbol
ken1
Assembly
GCA_035044365.1
Location
JAWNMD010000151.1:681242-683410[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.013 1 10.1 5.0 3 23 211 231 209 231 0.96
2 12 0.0022 0.17 12.6 0.2 1 23 237 262 237 262 0.92
3 12 0.0025 0.19 12.4 0.1 3 23 271 294 269 294 0.93
4 12 0.0073 0.56 11.0 1.8 2 23 307 328 306 328 0.96
5 12 1.1e-05 0.00081 19.9 0.6 1 23 335 357 335 357 0.98
6 12 0.0063 0.48 11.2 0.1 1 23 363 385 363 385 0.98
7 12 0.0097 0.74 10.6 2.2 1 23 391 414 391 414 0.97
8 12 0.0079 0.6 10.9 3.9 1 23 420 442 420 442 0.96
9 12 0.00096 0.073 13.7 2.9 2 23 449 470 448 470 0.96
10 12 9.1e-05 0.0069 17.0 1.6 1 23 562 585 562 585 0.95
11 12 0.0033 0.26 12.0 1.1 1 19 591 609 591 613 0.95
12 12 4.5e-06 0.00035 21.1 1.0 1 23 619 641 619 641 0.98

Sequence Information

Coding Sequence
ATGAGCACAGCCACAGCGTACTCTGTTCATTCAATATGTCGAGTTTGCTTAGTATACCTCGAGTGCTCCACAACATACGATCTGTTTTTATTGCCAGATCTTGCCAAGACATTCACAGTTTGCACGTCCTTATTGGTGGATCCCGAAGATGGCTATCCCAGGAATCTCTGTACGAGCTGTTATGCCAGATTAAATGATCTGCATGATTTTCAGCAGCTCTGTGTGTCATCTGTACAGCGTTTCAAGCAGATGGTCGCAAACAAGGCAATTGATTTCGTGGAACCGCTTCCCGTAGCCAGCAATGAGGCTGAATTATTGGTAAAGGATGAGGAACAGTCCAGTCTTGACTACGATCCACTGTTGAGCCACAAACTCGAATTGATTGGCAACGAAGAGGATGTCTTTAAAATGCTGGAAGACGTCGACAAGGAAGCTGAGGATGATAATGCTGTCCGGGAAAGGAGAATCTTCAGAGATACCTCATCAATGTCTTCCGAGAGCAGTCTTAGTGAGGATGATGTGCCATTGGCGCAACGTTTGTTGGAATACGACTCCGAATCCAAGCCTAAAGCGAAGACGAAACGTAAGCGAATCCCTCCAGGAGAGCGTCATCTTCATCGCATCATAATCTGCCACATTTGCAAGCAGAAATTCAAGAAGCAACTCAACTACGACGAGCACATGAAGCATCACAATGAACTGTTGCCCTTCCAGTGCAATATGGAGAGCTGCAAGAAGGGATTCACCACAGCAGCTGCACTGCGTCTTCACGTGGACTATGCACACACAAAGAGTGCCGaggaaataccctgtactgtGGAGGGTTGCAAGCTGTCTTTTCCACGCCTCAGATTGCTGACAATTCATCTGAAGAAGGTGCACAACATGTCCAGAGTCAGTGTGCCTCGCGTAGAGCAGTCTTGTAACGAGTGTGGAACGTTGTTCCGTTGTCCAGTGGCACTTAAGAAGCACATGTACAAACATACAGGAGAACAACTGCCGTATCCTTGCAATATTTGTGGCAAGGGCTTCCACATCAACAGCGCCTTGAAGAATCATTTGTTAAGGCACGCTGGCATCAAAAACTATGTGTGTCCCTACTGTGGTGTGGGCAAGACAACGCGACAAGAGTGGAGTAAACACATATTGACACACACCCAGGAGAAGATGTTCAAGTGCCAGATCTGTGACCATGCCACTCACACCAAGCGAGCGCTGGACAATCATGTAAAGATTGTGCACGAGAAGATTAGAAACTATGCCTGTCAGTATTGTGGCAAGACTTTTGGCAAGTCGCATGCCTGTAAAATCCATGAGATGACCCACACTGGAGAGAAGCGCTGTGAGTGCAAGGTCTGTGGCAAGAAGTTCCTTTACACAGAGAGTCTGACGAAGCATCTGAAGATCCACGAGAAGAGCGTGGAACGTGCCATAGAAACGTATCGTCAGCGTCAGGTGGAACTTGGAACTGAAGAGCAACAGAGCGAGAATACAGACTGCCAGGCAGCGGATCAACTGTTGAAGGTATGTGCTGAGTCTGTGGCCACCATACCACGAGATCCGAGACGTGTGGAGCGAGTAGATATATCCCAACTGGCTGGCACCGTCGTAAATCCCATACCCGCCGTGATTGTATCCTCGCATACACCAGCCCAAGTAAGCTTGGTGCAGAAGGAGGGCTTACATTTCTGTCCTGGTTGTAATCAGGGCTTCAACAACTTGGGCAACATGAAGCGACATTATAAGAGCGTTCATGAGAAGGTCAAGGATTTCGAGTGTCGTTTCTGCTCACGACGCTTTGCCAACTCGCAATCCCTGAAGCAACATGAATGGATTCATACCGGGGAAAAACCCTATGCCTGCAAGACTTGTGGTACACATTTCCGTCAGGAAGCGGCTTTAATACGCCATCAAAAGGTGCACGAAGAGAAGTCACCGAAGCCAGAGAAACCTCCAAAACAAATAACTGAAAAGTTCcgacaaaaagaaatacagaAGTGTGAGAAACGTCGCAATGTTGAAGCATTGCGTCAGAAGATTGCTGAAGCCGCCAAGGAGGAGCTGCAGGAACTGGCCAAACAACGTGAGCTGGAGAAGCAACAAAATACCTATGAACAGTATCAAGCAAAAGCTGCTGAAAGGACACAGATTCCAGAGGAGCTTACTTAG
Protein Sequence
MSTATAYSVHSICRVCLVYLECSTTYDLFLLPDLAKTFTVCTSLLVDPEDGYPRNLCTSCYARLNDLHDFQQLCVSSVQRFKQMVANKAIDFVEPLPVASNEAELLVKDEEQSSLDYDPLLSHKLELIGNEEDVFKMLEDVDKEAEDDNAVRERRIFRDTSSMSSESSLSEDDVPLAQRLLEYDSESKPKAKTKRKRIPPGERHLHRIIICHICKQKFKKQLNYDEHMKHHNELLPFQCNMESCKKGFTTAAALRLHVDYAHTKSAEEIPCTVEGCKLSFPRLRLLTIHLKKVHNMSRVSVPRVEQSCNECGTLFRCPVALKKHMYKHTGEQLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKMFKCQICDHATHTKRALDNHVKIVHEKIRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERAIETYRQRQVELGTEEQQSENTDCQAADQLLKVCAESVATIPRDPRRVERVDISQLAGTVVNPIPAVIVSSHTPAQVSLVQKEGLHFCPGCNQGFNNLGNMKRHYKSVHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHEEKSPKPEKPPKQITEKFRQKEIQKCEKRRNVEALRQKIAEAAKEELQELAKQRELEKQQNTYEQYQAKAAERTQIPEELT