Basic Information

Insect: Drosophila acutilabella
Gene Symbol: ken1
Assembly: GCA_035046005.1
Location: JAWNOK010000013.1:2513825-2516026[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0033 0.26 12.1 8.3 2 23 222 243 221 243 0.96

2 12 0.016 1.2 9.9 0.1 1 23 249 274 249 274 0.90

3 12 0.032 2.5 9.0 0.1 3 23 283 306 281 306 0.93

4 12 0.018 1.4 9.8 0.9 3 23 320 340 319 340 0.97

5 12 5.5e-06 0.00043 20.8 0.6 1 23 347 369 347 369 0.98

6 12 0.01 0.81 10.5 0.2 1 23 375 397 375 397 0.98

7 12 0.077 6 7.8 4.0 1 23 403 426 403 426 0.97

8 12 0.0081 0.63 10.8 3.9 1 23 432 454 432 454 0.96

9 12 0.00098 0.077 13.7 2.9 2 23 461 482 460 482 0.96

10 12 9.3e-05 0.0073 16.9 1.6 1 23 568 591 568 591 0.95

11 12 0.00071 0.055 14.2 1.0 1 19 597 615 597 619 0.95

12 12 4.7e-06 0.00036 21.0 1.0 1 23 625 647 625 647 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0033	0.26	12.1	8.3	2	23	222	243	221	243	0.96
2	12	0.016	1.2	9.9	0.1	1	23	249	274	249	274	0.90
3	12	0.032	2.5	9.0	0.1	3	23	283	306	281	306	0.93
4	12	0.018	1.4	9.8	0.9	3	23	320	340	319	340	0.97
5	12	5.5e-06	0.00043	20.8	0.6	1	23	347	369	347	369	0.98
6	12	0.01	0.81	10.5	0.2	1	23	375	397	375	397	0.98
7	12	0.077	6	7.8	4.0	1	23	403	426	403	426	0.97
8	12	0.0081	0.63	10.8	3.9	1	23	432	454	432	454	0.96
9	12	0.00098	0.077	13.7	2.9	2	23	461	482	460	482	0.96
10	12	9.3e-05	0.0073	16.9	1.6	1	23	568	591	568	591	0.95
11	12	0.00071	0.055	14.2	1.0	1	19	597	615	597	619	0.95
12	12	4.7e-06	0.00036	21.0	1.0	1	23	625	647	625	647	0.98

Sequence Information

Coding Sequence: ATGAGCACAGCCACAACCTATTCAGTTCATTCAATATGTCGTGTTTGCTTAGCCTACCTCGAGTGCTCCACAACGTTTGATCTGTTTTCACTGCCAGATCTCGCCAAGACATTCACAGTGTGCACATCCTTGTTGCTGGATCCCCAGGATGGTTATCCCAGAAAACTGTGTACGAATTGTTACGCCCGATTAAATGATTTGCATGATTTCCAGCAGCTGTGTTTGTCCTCTGTGCAGCGATTCAGACAAATGGTTGCCAGCAAAGTCATCGTCAATGTCAGGACCATCGATCTCTTGGAGCCTCTGACCGTAGCAGCCAGCAGTGAGCTGGTTAAGGATGAGGAACCCAGCACTGACTACGATCCACTGCTAAGCCACAAACTGGAGTTGATAGACAACGAAGAGGATGTCTTTAAACTGCTGGAAAATGTAGACAAGGAAGCAGGCGACGATTGTCAGGAGAGAGCAATTCGAGACTATTTGTCCACGTCTGCCGAGAGCAGTCTCAGTGAGGATGATGTACCGCTGGCGCAGCGCTTGCTCGAAAAGCACAGCGACGATACAGATAACTCTGAGTACGATTCAGCGTCTAAGCCCACATCCAAGACGAAAGGAAAACGCCAGCGAATTCCTCCAGAAGAGCGTCATCTACATCGTCTCATCAGCTGCCACATTTGCCAGCAGAAGTTCAAGAAGCGCCACAACTACGAGGAGCACATGAAGCATCACAATGAACTGCTTCCCTTTCAGTGCCAAATGGAGTCCTGCAGAAAGGGATTCACCACAGCGGCTGCACTGCGTCTTCATGCGGACTATGCTCACACAAAGCTAGCCGcagaaataccctgtactgtTCCAGACTGCAAGCAGCTATTTCCACGCATGCGACTGCTAACGATTCATCTAAAGAAGGTGCACAATTTGACGCGGGAAAGTGTTCCACGAGCGGAGCAAGCGTGCAGCGAGTGTGGACTGCTTTTCCGTTGTCCCGTGGCTCTCAAGAAGCACATGTACAAGCACACGGGCGAGCAGCTGCCATATCCTTGCAACATTTGCGGCAAGGCCTTTCACATCAATAGTGCTTTGAAGAATCATCTGCTGCGTCACGCGGGCATCAAGAACTATGTGTGTCCCTACTGTGGTGTGGGGAAGACTACGCGCCAGGAGTGGAGCAAACACTTGCTGACCCACACGCAAGAGAAGATGTTCAAGTGCCACGTCTGCGagcatgccacacacactaAGCGAGCGCTGGATAATCATGTCAAGATAGTGCATGAAAAGGTTCGCAATTATGCGTGTCAATATTGTGGCAAGACCTTTGGCAAATCCCACGCCTGTAAAATCCATGAGATGACTCACACGGGAGAGAAGCGTTGCGAGTGCAAGGTCTGTGGCAAGAAGTTTCTATACACCGAGAGCCTGACCAAGCATCTGAAGATACACGAGAAGAGTGTGGAGCGTGCCATTGAGACATATCGCCAGCGGCAGGTGGAGCTGGGCGAGGAGCAGCCCAGTGGAACGGCGGATCAACTGCTAAAGGTGTGCGCAGAGTCGGTGGCCACCATACCTCGTGATCCGCGTCGCGTGGAGCGTGTTGACATTGCTCAGCTGGCTGGCACCGTCATCAATCCCATACCTGCTGTTTTGGTGCAGCCAAATCCACCGGCTCAGACGCAACTTGTGCAGCAGGAGGGCATACACTTTTGTCCCGGCTGCAATCAGGGTTTTAACAATCTGGGCAATATGAAGCGTCACTACAAGAGCGTCCACGAAAAGGTCAAGGACTTTGAGTGTCGCTACTGCTCACGTCGCTTTGCCAATTCGCAATCCCTTAAGCAACACGAGTGGATTCACACGGGGGAAAAGCCCTATGCCTGCAAGACTTGTGGCACCCACTTTCGCCAGGAGGCGGCCCTGATACGCCACCAAAAGGTACACGAAGAGAAGCCAGCGAAGACCGAGAAGCCTCCAAAACAAATCACCGAAAAGTGCCGACAAAGGGAATTGCAGAAATGCGAAAAACGTCGCAGTGTGGAGGCACTGCGTCTGAAGATTGCCGAAGCTGCTAAGGAGGAGCTCCAAGAACTGGCTAAACAGCGGCAGCtggaaaagcaacaaaataccTATGAACAGTATCAAGCGACAGCTATCAAGAGCCACATACCAGACGACGATGAGACTAAATCTTCCACTTCCTAG
Protein Sequence: MSTATTYSVHSICRVCLAYLECSTTFDLFSLPDLAKTFTVCTSLLLDPQDGYPRKLCTNCYARLNDLHDFQQLCLSSVQRFRQMVASKVIVNVRTIDLLEPLTVAASSELVKDEEPSTDYDPLLSHKLELIDNEEDVFKLLENVDKEAGDDCQERAIRDYLSTSAESSLSEDDVPLAQRLLEKHSDDTDNSEYDSASKPTSKTKGKRQRIPPEERHLHRLISCHICQQKFKKRHNYEEHMKHHNELLPFQCQMESCRKGFTTAAALRLHADYAHTKLAAEIPCTVPDCKQLFPRMRLLTIHLKKVHNLTRESVPRAEQACSECGLLFRCPVALKKHMYKHTGEQLPYPCNICGKAFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHLLTHTQEKMFKCHVCEHATHTKRALDNHVKIVHEKVRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERAIETYRQRQVELGEEQPSGTADQLLKVCAESVATIPRDPRRVERVDIAQLAGTVINPIPAVLVQPNPPAQTQLVQQEGIHFCPGCNQGFNNLGNMKRHYKSVHEKVKDFECRYCSRRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHEEKPAKTEKPPKQITEKCRQRELQKCEKRRSVEALRLKIAEAAKEELQELAKQRQLEKQQNTYEQYQATAIKSHIPDDDETKSSTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558090;
90% Identity: iTF_00478918; iTF_00569162;
80% Identity: -