Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: ken1
Assembly: GCA_037043435.1
Location: JBAMBK010001570.1:369244-371421[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0029 0.21 12.4 5.3 2 23 209 230 208 230 0.96

2 12 0.0017 0.12 13.1 0.4 1 23 236 261 236 261 0.93

3 12 0.028 2 9.3 0.1 3 23 270 293 268 293 0.93

4 12 0.014 1 10.2 1.6 2 23 306 327 305 327 0.96

5 12 1.2e-05 0.00085 19.9 0.6 1 23 334 356 334 356 0.98

6 12 0.0069 0.5 11.2 0.1 1 23 362 384 362 384 0.98

7 12 0.057 4.1 8.3 2.0 1 23 390 413 390 413 0.97

8 12 0.0087 0.63 10.8 3.9 1 23 419 441 419 441 0.96

9 12 0.0011 0.077 13.7 2.9 2 23 448 469 447 469 0.96

10 12 0.00013 0.0097 16.6 1.1 3 23 565 586 563 586 0.95

11 12 0.013 0.97 10.3 0.7 1 19 592 610 592 614 0.95

12 12 5e-06 0.00036 21.1 1.0 1 23 620 642 620 642 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0029	0.21	12.4	5.3	2	23	209	230	208	230	0.96
2	12	0.0017	0.12	13.1	0.4	1	23	236	261	236	261	0.93
3	12	0.028	2	9.3	0.1	3	23	270	293	268	293	0.93
4	12	0.014	1	10.2	1.6	2	23	306	327	305	327	0.96
5	12	1.2e-05	0.00085	19.9	0.6	1	23	334	356	334	356	0.98
6	12	0.0069	0.5	11.2	0.1	1	23	362	384	362	384	0.98
7	12	0.057	4.1	8.3	2.0	1	23	390	413	390	413	0.97
8	12	0.0087	0.63	10.8	3.9	1	23	419	441	419	441	0.96
9	12	0.0011	0.077	13.7	2.9	2	23	448	469	447	469	0.96
10	12	0.00013	0.0097	16.6	1.1	3	23	565	586	563	586	0.95
11	12	0.013	0.97	10.3	0.7	1	19	592	610	592	614	0.95
12	12	5e-06	0.00036	21.1	1.0	1	23	620	642	620	642	0.98

Sequence Information

Coding Sequence: ATGAGCACAGCCACAACGTACTCAGTTCACTCAATATGTCGAGCTTGCTTAGTGTACCTCGAGTGCTGTAAAAAATACGATCTGTTTTCATTGCCAGATCTCGCCAAGACATTCACAGTGTGCACGTCCTTGTTGGTGGAGCCCCAAGATGGCTACCCGAGGAATCTCTGCGGCAGCTGTTACGCCCGTCTAAATGATCTGCATGACTTTCAGCAATTGTGTGTGGCGTCCGTGCAGCGTTTTAAGCAAATGGTGGCCAGCAAAGTTGTTATTAATGCCAAgacaattgatttatttgaaGCACTTCCAGTGGCCAGCAATGAGACGGAGCTGCTGGTCAAGGATGAGCATGAGCCCAGCATGGATTACGATCCACTGCTGAGCCACAAATTGGAGATTGACAACGTAGAGGATGTGTTCAAATTGCTAGAGAATGTGGACAAGGAAGCGGAGGAGGGTGTGAGCAGGgattcctcctcctcctcgtcctcCTCCGAGCACAGTCTCAGTGAGGATGATGTGCCGCTGGCACAACGCCTAGGTGAATCCCAGTCAACTCCAGCCAAATCCAAGACGAAACGCAAGCGCATTCCTCGAGCGGAGCGTCATCTGCATCGCATCATCAGTTGTCACATTTGCCAGCAGAAGTTCAAAAAGCAACTCAACTACGAGGAGCACATGAAGCATCACAATGAACTGCTGCCCTTTCAGTGCCATGTGGAGAGCTGCAAGAAGGGTTTCACCACAGCGGCTGCACTGCGTCTGCATGTGGACTATGCGCACACCAAGACTGTGGAGGAGATACCCTGCACTGTTGAGGGCTGCAAGCTGTTGTTTCCACGCCTCCGATTGCTAACGATTCACCTGAGAAAGGTGCACAACATGTCCAGGGCGAGTGTGCCGCGCGTGGAGCAATCTTGCAGTGAGTGTGGCATGCTCTTCCGCTGTCCCGTGGCCCTGAAGAAGCATATGTACAAGCACACGGGTGAACAGCTGCCGTATCCCTGCAATATCTGTGGCAAGGGCTTCCACATCAATAGCGCTCTAAAGAATCATCTGCTCCGTCATGCGGGCATCAAGAACTATGTGTGTCCCTATTGTGGCGTGGGCAAGACCACACGGCAGGAGTGGAGCAAACACATACTCACCCACACGCAGGAGAAGATGTTCAAGTGCCAGATCTGTGAGCATGCCACGCACACCCGGCGAGCTCTCGATAATCACGTCAAGATTGTGCACGAGAAGATTAGGAACTATGCGTGCCAATATTGTGGCAAGACCTTTGGCAAATCGCATGCTTGCAAGATCCACGAGATGACGCACACGGGCGAGAAGCGTTGCGAGTGCAAGGTGTGTGGCAAGAAGTTCCTCTACACGGAGAGTCTGACGAAGCATCTGAAGATTCACGAGAAGAGCGTGGAGCTTGCCATTGAAACGTATCGCCAGAGGCAGGTTGAACTTGGTGAGGGAGCTGCGGAGCCACCGAGTGGTCAAACAGATGACCCGGCAGCGGATCAACTGTTAAAGGTGTGTGCGGCGTCTGTGGCCACTATTCCTCGTGATCCTAGGCGTGTGGAACGCGTGGACTTGTCTCAGCTGGCTGGCACCGTTCTCAATCCCATACCCGCCGTCCAGGTAGACACAAATCCACCAGCTCAAGGAAATTTCGTGCAAAAGGAGGGCCTACACTTGTGTCCTGGCTGCAATCAGGGATTCAACAACTTGGGCAACATGAAGCGACATTATAAGAGTGTTCACGAGAAGGTCAAAGACTTTGAGTGTCGCTTCTGTGCACGTCGCTTTGCCAACTCGCAGTCCCTCAAGCAGCATGAATGGATTCACACCGGCGAGAAGCCCTACGCCTGCAAGACCTGTGGCACCCATTTCCGGCAGGAGGCGGCCCTCATACGCCACCAGAAGGTGCACGAAGAGAAGTCGTCAAAGCCGGCGAAGCCGCCCAAACAAATCACTGAAAAGTTTCGTCAAAAGCAAGTCCAGAAATGTGAGAAACGTCGCAAGGTGGAAGCGTTGCGAGAGAAGATCGCGGAAGCGGCCAAAGAGGAGCTGGAGGAACTGGCCAAACAGCGTGAGCTGGAGAAGCAACAAAATACCTATGAACAGTATCAGGCGGCAGCTAAGAGAATCCCACAGATTCCACACGAATCCGCGAATATCTGA
Protein Sequence: MSTATTYSVHSICRACLVYLECCKKYDLFSLPDLAKTFTVCTSLLVEPQDGYPRNLCGSCYARLNDLHDFQQLCVASVQRFKQMVASKVVINAKTIDLFEALPVASNETELLVKDEHEPSMDYDPLLSHKLEIDNVEDVFKLLENVDKEAEEGVSRDSSSSSSSSEHSLSEDDVPLAQRLGESQSTPAKSKTKRKRIPRAERHLHRIISCHICQQKFKKQLNYEEHMKHHNELLPFQCHVESCKKGFTTAAALRLHVDYAHTKTVEEIPCTVEGCKLLFPRLRLLTIHLRKVHNMSRASVPRVEQSCSECGMLFRCPVALKKHMYKHTGEQLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKMFKCQICEHATHTRRALDNHVKIVHEKIRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVELAIETYRQRQVELGEGAAEPPSGQTDDPAADQLLKVCAASVATIPRDPRRVERVDLSQLAGTVLNPIPAVQVDTNPPAQGNFVQKEGLHLCPGCNQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYACKTCGTHFRQEAALIRHQKVHEEKSSKPAKPPKQITEKFRQKQVQKCEKRRKVEALREKIAEAAKEELEELAKQRELEKQQNTYEQYQAAAKRIPQIPHESANI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558090;
90% Identity: iTF_00586140;
80% Identity: -