Basic Information

Insect: Drosophila phalerata
Gene Symbol: ken1
Assembly: GCA_951394115.2
Location: OX596004.2:37757166-37759346[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0013 0.13 13.3 2.7 3 23 206 226 204 226 0.96

2 12 0.0076 0.74 10.9 0.2 1 23 232 257 232 257 0.90

3 12 0.031 3.1 9.0 0.1 3 23 266 289 264 289 0.94

4 12 0.0057 0.56 11.3 1.6 2 23 302 323 301 323 0.96

5 12 1.1e-05 0.001 19.9 0.6 1 23 330 352 330 352 0.98

6 12 0.01 1 10.5 0.2 1 23 358 380 358 380 0.98

7 12 0.052 5.1 8.3 2.0 1 23 386 409 386 409 0.97

8 12 0.0079 0.78 10.8 3.9 1 23 415 437 415 437 0.96

9 12 0.00096 0.095 13.7 2.9 2 23 444 465 443 465 0.96

10 12 0.00022 0.022 15.7 1.1 3 23 559 580 557 580 0.95

11 12 0.0007 0.069 14.2 1.0 1 19 586 604 586 608 0.95

12 12 1.4e-06 0.00014 22.7 0.6 1 23 614 636 614 636 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0013	0.13	13.3	2.7	3	23	206	226	204	226	0.96
2	12	0.0076	0.74	10.9	0.2	1	23	232	257	232	257	0.90
3	12	0.031	3.1	9.0	0.1	3	23	266	289	264	289	0.94
4	12	0.0057	0.56	11.3	1.6	2	23	302	323	301	323	0.96
5	12	1.1e-05	0.001	19.9	0.6	1	23	330	352	330	352	0.98
6	12	0.01	1	10.5	0.2	1	23	358	380	358	380	0.98
7	12	0.052	5.1	8.3	2.0	1	23	386	409	386	409	0.97
8	12	0.0079	0.78	10.8	3.9	1	23	415	437	415	437	0.96
9	12	0.00096	0.095	13.7	2.9	2	23	444	465	443	465	0.96
10	12	0.00022	0.022	15.7	1.1	3	23	559	580	557	580	0.95
11	12	0.0007	0.069	14.2	1.0	1	19	586	604	586	608	0.95
12	12	1.4e-06	0.00014	22.7	0.6	1	23	614	636	614	636	0.98

Sequence Information

Coding Sequence: ATGAGCACAGCCAGAACGTACTCAATTGATTCCATATGTCGAGTTTGTTTAGTCCACCTCGAGTGCGCCACAACATATGACCTGTTTTTATTGCCAGATCTCGCCAAGACATTCACAGTATGCACATCCTTGCTGCTGGAGCCCCAAGATGGCTACCCAAGGAATCTCTGCGCCAGCTGTTACGCCCGGTTGAAGGATCTCGATGAATTCCGGCGGTTGTGTGTGACATCCGTGCAGCGGTTCAAGCAAATGTTGGAAAACAAAGTGGTTAACTTATTTCCCATCCTGGCCAGCAATGAGTCGGAGCTGCTGTTGGTTAAGGATGAGCAGGAACCCAGCACGGATTATGATCCGCTGTTGAGTCACAAATTGGAGATTGACAACGTTGAGGATGTGTTTAAACTGCTGGAGAGTGTGGACAAGGAGgcagaggaggaggaggagggaaTCGCTAGGGATTCATCTGCCTGCTCCCAGAGCAGTCTCAGTGAGGATGATATGCCGCTGGCGCAACGTCTGCTGGAAACGGAGGAATCCCCCTCAAGTCCCACCAAATCCAAGACGAAACGCCAGCGAATTCCTCGAGCGGAACGACATCTGCATCGCATCATCAACTGTGAGATTTGTCAACAGAAATTTAAGAAACAACTCAACTACGAGGAGCATATGAAGCATCACAATGAACTGTTGCCCTTTCAGTGTCGCATGGAGAGCTGCAAGAAGGGATTCACCACAGCGGCTGCACTGCGTCTGCATGTGGACTATGCGCACAGCAAGAGCGACGCCGAGATACCCTGTACTGTCGCAGACTGCAAGCTGTTGTTTCCACGCCTGAGACTGCTCACAATACACCTGAAAAAGGTGCATAATCTGAGCAGAGCGAGTGCTCCACGCATGGAGCAATCCTGTCGAGAATGTGGCATGATCTTTCGCTGTCCCGTGGCTCTGAAGAAGCATATGTATAAGCACACAGGGGAACAGCTCCCATATCCGTGTAATATCTGTGGCAAGGGATTTCATATTAATAGCGCCTTGAAGAATCATTTGCTGCGTCATGCGGGGATTAAGAACTATGTGTGTCCATACTGTGGCGTGGGCAAGACCACCAGGCAGGAGTGGAGCAAGCATTTACTCACCCACACGCAGGAGAAGATGTTCAAGTGCCAGATCTGTGAACATGCCACGCACACGAGAAGAGCACTGGATAATCATGTCAAGATTGTGCATGAGAAGATTAGGAACTATGCGTGTCAGTATTGTGGCAAGACCTTTGGCAAATCGCATGCTTGTAAGATCCATGAGATGACGCACACGGGTGAGAAGCGTTGCGAGTGTAAAGTCTGTGGCAAGAAGTTCCTCTATACGGAGAGTCTTACCAAGCATCTGAAGATTCATGAGAAGAGCGTGGAGCGAGCGATTGAGACATATAGACAGCGACAGGTGGAACTGGGTGATGCAGGAGTGGAGCAACCAAGTGGAAATGTGGATGACCCGGCGGCGGATCAACTCTTGAAGGTGTGTGCGGCATCTGTGGCCACCATACCCAAGGATCCGAGACGTGTGGAACGTGTGGAGTTGTCCCAACTGGCTGGCACCGTGGTCAATCCCATACCCTCTATCCAACTAACCACAAATCCAGCTGGAAACTTGGTGCAAAAGGAGGGACTGCATTTATGTCCTGGCTGCCAGCAAGGATTCAACAATCTGGGCAACATGAAGCGACACTACAAGAGCGTCCATGAGAAGGTCAAGGACTTTGAGTGTCGGTACTGTTCCCGTCGCTTTGCCAACTCCCAATCCCTGAAGCAACACGAATGGATTCACACCGGAGAGAAACCCTATGCCTGCAAGATTTGTGGTACACATTTCCGTCAGGAGGCGGCTTTAATACGTCACCAAAAGGTGCACGAAGAGAAGCCCCCAAGACCAGAGAAACCTCCCAAACAAATTACAGAAAAGTATCGACAAAAACAAGTCCAGAAATGTGAGAAACGTCGCAATGTGGAAGCGTTGCGGGAGAAGATCGCTGAAGCAGCCAAGGAGGAGCTGCAGGAATTGGCCAAACAGCGGGAACTGGAGAAGCAACAAAATACCTATGAACAGTATCAAGCGGCAGCTAAAAAAATCCCACAGATACCAGAGATCCCAGAGAAATCCGAGGATAAAACTCTGCTCAACTGA
Protein Sequence: MSTARTYSIDSICRVCLVHLECATTYDLFLLPDLAKTFTVCTSLLLEPQDGYPRNLCASCYARLKDLDEFRRLCVTSVQRFKQMLENKVVNLFPILASNESELLLVKDEQEPSTDYDPLLSHKLEIDNVEDVFKLLESVDKEAEEEEEGIARDSSACSQSSLSEDDMPLAQRLLETEESPSSPTKSKTKRQRIPRAERHLHRIINCEICQQKFKKQLNYEEHMKHHNELLPFQCRMESCKKGFTTAAALRLHVDYAHSKSDAEIPCTVADCKLLFPRLRLLTIHLKKVHNLSRASAPRMEQSCRECGMIFRCPVALKKHMYKHTGEQLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHLLTHTQEKMFKCQICEHATHTRRALDNHVKIVHEKIRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERAIETYRQRQVELGDAGVEQPSGNVDDPAADQLLKVCAASVATIPKDPRRVERVELSQLAGTVVNPIPSIQLTTNPAGNLVQKEGLHLCPGCQQGFNNLGNMKRHYKSVHEKVKDFECRYCSRRFANSQSLKQHEWIHTGEKPYACKICGTHFRQEAALIRHQKVHEEKPPRPEKPPKQITEKYRQKQVQKCEKRRNVEALREKIAEAAKEELQELAKQRELEKQQNTYEQYQAAAKKIPQIPEIPEKSEDKTLLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558090;
90% Identity: iTF_00523140; iTF_00507069;
80% Identity: -