Basic Information

Insect: Drosophila mayri
Gene Symbol: -
Assembly: GCA_008042485.1
Location: VNJN01009363.1:1488075-1491997[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.9e-05 0.0055 16.9 0.4 1 23 171 194 171 194 0.96

2 14 0.0016 0.11 12.9 3.1 2 23 243 265 239 265 0.90

3 14 0.0067 0.47 10.9 0.8 1 23 361 384 361 384 0.93

4 14 0.0046 0.32 11.4 3.8 2 23 433 454 432 455 0.94

5 14 0.00061 0.043 14.1 0.4 1 23 524 547 524 547 0.92

6 14 1.8 1.2e+02 3.2 0.1 2 14 566 578 565 590 0.85

7 14 0.00087 0.061 13.7 4.2 2 23 598 620 598 620 0.97

8 14 0.042 2.9 8.4 0.8 1 23 714 737 714 737 0.95

9 14 4.5e-05 0.0032 17.7 0.3 1 23 771 794 771 794 0.93

10 14 0.0038 0.27 11.6 1.5 2 23 844 866 843 866 0.95

11 14 0.017 1.2 9.6 1.8 1 23 963 986 963 986 0.91

12 14 0.0019 0.13 12.6 1.4 1 21 1038 1058 1038 1059 0.95

13 14 3.2 2.3e+02 2.4 0.1 3 23 1091 1114 1089 1114 0.74

14 14 3.8 2.7e+02 2.2 0.3 1 11 1134 1144 1134 1158 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.9e-05	0.0055	16.9	0.4	1	23	171	194	171	194	0.96
2	14	0.0016	0.11	12.9	3.1	2	23	243	265	239	265	0.90
3	14	0.0067	0.47	10.9	0.8	1	23	361	384	361	384	0.93
4	14	0.0046	0.32	11.4	3.8	2	23	433	454	432	455	0.94
5	14	0.00061	0.043	14.1	0.4	1	23	524	547	524	547	0.92
6	14	1.8	1.2e+02	3.2	0.1	2	14	566	578	565	590	0.85
7	14	0.00087	0.061	13.7	4.2	2	23	598	620	598	620	0.97
8	14	0.042	2.9	8.4	0.8	1	23	714	737	714	737	0.95
9	14	4.5e-05	0.0032	17.7	0.3	1	23	771	794	771	794	0.93
10	14	0.0038	0.27	11.6	1.5	2	23	844	866	843	866	0.95
11	14	0.017	1.2	9.6	1.8	1	23	963	986	963	986	0.91
12	14	0.0019	0.13	12.6	1.4	1	21	1038	1058	1038	1059	0.95
13	14	3.2	2.3e+02	2.4	0.1	3	23	1091	1114	1089	1114	0.74
14	14	3.8	2.7e+02	2.2	0.3	1	11	1134	1144	1134	1158	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCGATGTTCTCCTCTGAGCTCGAGGACGGTGAGCCAGAAGGGGGAGGCGAGGGAGAGCTGCTGGACGGTGAGGATGGGGCGCAGTACGGCAACGGAAATGGCGACTTAATCGACGACACGGCGATCCTGGAGGCTGGAGAGGGCGTAGAGGACCTGCTAGATGGCGAGGACGATGATCGGGAGGAGGACGACGAAGATGGCATGGAAAAGAAGTCAAAGGGACCGGAACCGGACGACGATGCCCTCTTCGACTTTGAGCTGGAGCCGATTATTAGTATTGGGGAGTCATCGCCGGCTTCGGTTCTGCCGCCTGCCGGTCCGATGGGCGCCCAAGTGCGTCCAGCCCTGCAGCGGCATTCACTGCCCCCGCTTACTCGGCCGCGAGCCGATATGCGGCCCATTGGGTTTCCCGTGCGTCCCACCACCTCACAGATCAATGCTACTGATGAGAATGGCGTGCCAATTAACTACGAGCTGGGCGTGGTGTACATCTGCCCAGCCTGTGGTGGAGAGTTCCGACAGCAGGACCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACGCTTCGGGGCCTCAACTTTGCACCGCTGGACAAGCTGTATCAGCGCTGCAAGGAGTGCCACAAGCGAATTGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACGCATCTGCCGTTCCGGTGCACAAAGTGTTACATCTGCAAGCGGGAGTACAAATACAGGCAAGATCTTATGGTGCATCTGCGCATGGTACACTGCGACGAAGTGGTAGCCATGATGCGGGAAGGTTACAATGCTGCCGGACGTAAAACCCGTGTCCGAGAGTCTCGTACAGAGCAATTGCAACGGGTGAAGAGTTTTCTAGAGGGTGACGACCTAGATCTCATCGAGGTGCGAAATGAGCTGCTCGAGCCGGATGTTGTTGAGTCAGGCGGCATGGTGCATCATCCGTCGCGGCTAGTAGAGGAGACGCCCCAAAAGAAGCGACCTGGCGGCAGTGGCGGCGGAGAAGCCGCTGAGCTGTGCGAGGATTACATTCACTACATGTGCCCTGACTGCGGCACTGAGTGCGACACCCACGCACAGTGGAGTCAGCACATTGAGTTTGTCCACGACTATGTCAGCCGGCGTGGCCTCAACTTTCGGAGTGTTGACATGCAGATGCAGTGCCTCGAATGCAAAAAGATTGTGACGCCCAACACCATCAAGACGCTGCGCGCCCACAAATTTAGTCACTTGTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGAGCACTCGGAACTGGTTAGGCATTTGCTTAAGCATCATCATTTGGAGACTCTGATGCCGGAGGAGCCAGGTCAGGAAGAGGAGGATGCCTCACAGATCTTGGATGGGGGAAATGACTTCGAAGACAATGGCAATTGCGAGGGCAACGGCGCCGCACTGGACGAAGATTCACCCTACTTTGAAGACGCCCCCCGGCGTGGCGGTCGTATTAGCAGCGATGACATTTTCGAACCGCACATCGACTACCTCTGTCCACAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCACGTAGTCATGGCGCACAGCATGAACGATCTGTCCAAGCTGAATTTCGAGATGATCAGCGAACGGCAGCTAAAGTGCACCGAATGCGACAAGATCATCACGAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATAACCCATCTGCCGTTCAAGGCGTATGCCAGATGCCGCAAGTGCCACAAGTCCTACACGGACCGAAAGGGTCTCGTCAAGCATCTGTCCACCTATCACCGCATCGGCTGTGATGCTCGCAAGTCTGGTGGAGGTGCAGCACCACCTTTACCAATGCTAACTACCCCCAAGCAGCCCCGCAAGCAGATCGTCACCGTGGCCAATGAGACCTACGAGATTATCTACTTGGACGATATGGATCAGAGCAGCTTGGAGGAGGAGAATGACTTTGGGGAACAGATGCTCGCTGACGAAGATGATTACCCGGTTATCCAGCCACCGCAACAGCGTCAGTTGCCACCTCCACCACGTCCCCCTTCGCTGAACACTCAGCAGCGCTACAAGTGCGTCCACTGCAGCACTCTCTTTCCCACACAGATGGCCGTGCGGGTGCACATCAGCGAGAAGCATAGCCGGAAGCCCCATCAGACGGGCAGAAGGCATCGCCTTATGATTTCGAATTCCGGTGGAGCAGACTCTGGGCTTACCACCGTAGAGCAGAACTACATCTTCCTATGCCCTTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAACGAGGAGCACAACTTCGACAAGCGAAACTACCTGAATATGCGGCAGTTGGACAAGTATCGCTACCAGTGCACGCAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTGCAGGACCATCACTTCCGTCACCTGCCATTCCGCCTGTATCTCAAGTGCTTGGTTTGCGGCACCTGCTATAACCACAAACCGAACATAGCGGCACATCTCAGGGCGCGCCACAACATCTTCGACAGGGAGACGCCCCTAATGGTCACCAAGCCGATGAAAGCCTACAATCGCTTCAAGGATGGGGAGAAAGAGAAGATCCCGCTACCCACTCCCGCACCGGCAGCTGGTTCTCCACCCGGCTGCtctgcctcctcctccccaGCTATGGCGGCTGCTGCGCCAGTGGTCAGTCGCACTCTTAAACCCCAACCCGGTGACCTGCCAACGCGACCCGCCGGCCTCAACACCCTGGAGGACAGCATCTCGTACCACAATGCCGTAGATATGGACTTCATTACGTACTTCTGCCCAAAATGCAATCAGAACTTCGACTCTCATGCCTTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAAGGTCTGAACTTCCGACAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACGGTGACCCACACCAAGGGCGCCATTGGTCAGCTGCAATCGCACAAGTTCCGGCATCTTCCCCATCGCTCCTTCAAGTGTTTGACCTGCGACGCCTCGTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGAGACACTAACCGGTGTGACAATCGTCCGCAACGCGAATTGGACGATGAAGAGCCCAGCCAGGACTCACAGCTGAGCACCATTTACCATTTGGCCTGTCCGCAGTGCGGCGATGACTTCAACACCCCCAGTCGGAAGCAGTGGCGCGATCACATTAACATCCTTCACGGCCTGACCGCGCTGGACCTGCTGCACATGAACAAGGTGGATGGCGCTGAGGATCTGTATCGCTGCCAGGACTGCAACGAGGAGCTGCAGACGAACCGGCAGTGGGTGCTGCAATACCACCGCTTCCAGCATCTTCCACAGCCGGCCTACATCCGCTGCCAGCTATGCGAGCAGAGTAGTGAGCGTGATGCGACAGTGGGATCCGGACTACACAGTCTACGTGAGCTGCAACAGCATCTACGCAAGCACCATCCCTCAACGGTGGGCGAGAACGAGATGCAGATACTGCGCGAACAGATTGCCCAGGAagagaaggagcaggaggagacCGTAGGCCAGGCCGCAGATGAAGAGGACAACCAGATGGGCCAGGACTCAGGACCCTACATGCCGCTTCCGCCGCATTTATTGGACGACGCAGACGACATGGAATTTGAGGACCAGTATTTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSELEDGEPEGGGEGELLDGEDGAQYGNGNGDLIDDTAILEAGEGVEDLLDGEDDDREEDDEDGMEKKSKGPEPDDDALFDFELEPIISIGESSPASVLPPAGPMGAQVRPALQRHSLPPLTRPRADMRPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQLQRVKSFLEGDDLDLIEVRNELLEPDVVESGGMVHHPSRLVEETPQKKRPGGSGGGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKTLRAHKFSHLSHPEWLRCKLCYKGYTEHSELVRHLLKHHHLETLMPEEPGQEEEDASQILDGGNDFEDNGNCEGNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMISERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLSTYHRIGCDARKSGGGAAPPLPMLTTPKQPRKQIVTVANETYEIIYLDDMDQSSLEEENDFGEQMLADEDDYPVIQPPQQRQLPPPPRPPSLNTQQRYKCVHCSTLFPTQMAVRVHISEKHSRKPHQTGRRHRLMISNSGGADSGLTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPLMVTKPMKAYNRFKDGEKEKIPLPTPAPAAGSPPGCSASSSPAMAAAAPVVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSQDSQLSTIYHLACPQCGDDFNTPSRKQWRDHINILHGLTALDLLHMNKVDGAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQSSERDATVGSGLHSLRELQQHLRKHHPSTVGENEMQILREQIAQEEKEQEETVGQAADEEDNQMGQDSGPYMPLPPHLLDDADDMEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00488969;
90% Identity: iTF_00488969; iTF_00613098; iTF_00491795; iTF_00617915; iTF_00478301; iTF_00490365; iTF_00524690; iTF_00562034; iTF_00594837; iTF_00594108;
80% Identity: -