Basic Information

Insect: Drosophila birchii
Gene Symbol: -
Assembly: GCA_008042755.1
Location: VNKA01002198.1:50250-54145[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8e-05 0.0065 16.9 0.4 1 23 162 185 162 185 0.96

2 14 0.0016 0.13 12.9 3.1 2 23 234 256 230 256 0.90

3 14 0.0068 0.55 10.9 0.8 1 23 351 374 351 374 0.93

4 14 0.0047 0.38 11.4 3.8 2 23 423 444 422 445 0.94

5 14 0.00062 0.05 14.2 0.4 1 23 515 538 515 538 0.92

6 14 1.8 1.5e+02 3.2 0.1 2 14 557 569 556 581 0.85

7 14 0.00062 0.051 14.1 3.3 2 23 589 611 589 611 0.96

8 14 0.042 3.4 8.4 0.8 1 23 706 729 706 729 0.95

9 14 4.6e-05 0.0037 17.7 0.3 1 23 763 786 763 786 0.93

10 14 0.0039 0.32 11.6 1.5 2 23 836 858 835 858 0.95

11 14 0.017 1.4 9.6 1.8 1 23 955 978 955 978 0.91

12 14 0.0019 0.16 12.6 1.4 1 21 1030 1050 1030 1051 0.95

13 14 3.3 2.7e+02 2.4 0.1 3 23 1083 1106 1081 1106 0.74

14 14 3.9 3.1e+02 2.2 0.3 1 11 1126 1136 1126 1150 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8e-05	0.0065	16.9	0.4	1	23	162	185	162	185	0.96
2	14	0.0016	0.13	12.9	3.1	2	23	234	256	230	256	0.90
3	14	0.0068	0.55	10.9	0.8	1	23	351	374	351	374	0.93
4	14	0.0047	0.38	11.4	3.8	2	23	423	444	422	445	0.94
5	14	0.00062	0.05	14.2	0.4	1	23	515	538	515	538	0.92
6	14	1.8	1.5e+02	3.2	0.1	2	14	557	569	556	581	0.85
7	14	0.00062	0.051	14.1	3.3	2	23	589	611	589	611	0.96
8	14	0.042	3.4	8.4	0.8	1	23	706	729	706	729	0.95
9	14	4.6e-05	0.0037	17.7	0.3	1	23	763	786	763	786	0.93
10	14	0.0039	0.32	11.6	1.5	2	23	836	858	835	858	0.95
11	14	0.017	1.4	9.6	1.8	1	23	955	978	955	978	0.91
12	14	0.0019	0.16	12.6	1.4	1	21	1030	1050	1030	1051	0.95
13	14	3.3	2.7e+02	2.4	0.1	3	23	1083	1106	1081	1106	0.74
14	14	3.9	3.1e+02	2.2	0.3	1	11	1126	1136	1126	1150	0.72

Sequence Information

Coding Sequence: ATGGAGGGCATGGACCTGTGGACGTCGATGTTCTCCTCTGAGCTCGATGACGGTGAGCCAGAGGGGGGCGGCGAGGGGGAGCTGCTGGACGGTGGCGAGGATGGGGCGCAGTATGGCAACGGAAATGGCGACTTGCTCGACGACACGGCGATCCTGGAGGCTGGAGAGGGCGTAGAGGACCTGCTAGATGGCGAGGACGATGAGCGGGAGGAGGACGACGAAGATGGAAGCATGGAAAAGAAGTCAAAGGGACCGGAACCGGACGACGATGCTCTGTTTGACTTCGAGCTGGAGCCGATTGTTAGTATTGGGGAGTCGTCGCCGGCTTCGGTTCTGGCTCCCGCCGGTCCCATGCGCCCGTCCCTGCAGCGGCATTCACTGCCCCCGCCTAATCCTTCCCGGCTTCCCGGGCGCCCCACCACCTCACAGATCAATGCCACCGACGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATCTGCCCAGCCTGTGGCGGCGAGTTCCGCCAGCAGGACCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACCCTGCGGGGCCTCAACTTTGCGCCGCTGGACAAGCTGTATCAGCGCTGCAAGGAGTGCCACAAGCGAATCGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACGCATTTGCCATTCCGGTGCACAAAGTGTTACATCTGCAAGCGGGAGTACAAATACAGGCAAGATCTTATGGTGCATCTGCGCATGGTGCACTGCGACGAAGTGGTGGCCATGATGCGGGAAGGCTACAATGCTGCCGGACGCAAGACCCGTGTCCGAGAGTCTCGCACAGAGCAAATGCAGCGGGAGAAGAGCTTTCTAGAGGGCGATCATGACCTAGATCATATCGAAGTGCGAAACGAGCTGCTTGAACCGGATGTTGATGAGTCGGGCGGCATGGTGCATCATCATCCGCCGCGGCTGGCAGAGGAGACGCCCCAGAAGAAGCGATCCGGCGGCGGTGAAGCTGCTGAGCTGTGCGAGGACTACATTCACTACATGTGCCCCGACTGCGGCACCGAGTGCGACACCCATGCGCAGTGGAGTCAGCACATTGAGTTTGTCCACGACTATGTCAGCCGGCGTGGCCTCAACTTCCGGAGTGTCGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTGACACCCAACACCATCAAATCGCTGCGCGCCCACAAATTCAGTCACTTGTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGAGCATTCGGAGTTGGTTAGGCATCTGCTGAAGCATCATCATTTGGAGACTCTGATGTCGGAGGAGCCGGGACAGGAAGGGGAGGAGGATGCCGCACAGACCATGGATGGGGGAAATGAATTCGAGGACAATGGCCATGGCGAGGGAAACGGCGCCGCCTTGGATGAGGATTCACCCTACTTTGAAGACGCCCCCCGGCGCGGCGGTCGTATTAGCAGCGATGACATTTTCGAACCGCACATTGACTACCTTTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCACGTAGTCATGGCGCACAGCATGAACGATCTGTCCAAGCTGAACTTCGAGATGATCAACGAACGGCAGCTAAAGTGCACCGAATGCGACAAGATCATCACGAATGCCTATGGCATACAGAACGCCCAGCAGCACAGGATCACCCATCTGCCGTTCAAGGCGTATGCCAGATGCCGCAAGTGCCACAAGTCCTACACGGACCGGAAGGGTCTCGTCAAGCATCTGGCCACCTATCACCGCATCGGCTGTGAGGCTCGCAAGTCTGGTGGTGGAGCAGCACCACCTTTACCCATGCTAACTACCCCCAAGCAGCCCCGAAAGCAGATCGTCACCGTGGCCAACGAGACCTATGAGATTATCTACTTGGACGATGTGGAGCAGAGCAGCTTGGAGGAGGAGAATGACTTTGGGGAACAGATGCTCGCCGACGAAGACGATTACCCGGTTGTACAGCCACCGCAACAGCGTCAGTTGCCGGCTCCACAGCCGCGACCCCCTTCGCAGATTACTCAGCAGCGCTACAAGTGCGTCCACTGCAGCACTCTCTTTCCCACACAGATGGCTGTGCGGGTGCACATCAGCGAGAAGCATAGCCGAAAGCCCCATCAGGCGGGCAGGAGGCATCGCCTTATGATTTCAAATTCCGGTGGAGCAGACTCTGGCCTTACCACCGTCGAGCAGAACTACATCTTCCTGTGCCCGTCGTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAATGAGGAGCACAACTTCGATAAGCGGAACTACCTCAACATGCGGCAGTTGGACAAGTATCGCTACCAGTGCACGCAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTGCAGGACCATCACTTCCGTCACCTGCCATACCGCCTGTATCTCAAGTGCTTGGTTTGCGGCACCTGCTATAACCACAAGCCGAACATAGCGGCACATCTCAGGGCGCGCCACAACATCTTCGACAGGGAGACGCCCCTAATGGTCACCAAGCCGATGAAAGCCTATAATCGCTTCAAGGATGGGGATAAGGAGAAGATTCCGATACCCACTCCCGCCCCGGCAGCTGGTTCTCCACCCGGCTGCTCTTCCTCCGCCTCTCTAGCTGTTCCAGCTGCTGCGCCAGTGGTCAGTCGCACTTTGAAACCCCAACCCGGTGACCTGCCAACGCGACCCGCCGGCCTGAACACCCTGGAAGACAGCATCTCTTACCACAATGCCGTAGATATGGACTTCATCACGTACTTCTGCCCAAAGTGCAACCAGAACTTCGACTCTCATGCCTTCTGGCGCAAGCACATTGTGGAGCAGCACAACTTTAACAGCCGCGAAGGCCTGAACTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACGGTGACCCACACCAAGGGCGCCATTGGTCAGCTGCAGTCGCACAAGTTCCGGCATCTTCCCCATCGCTCCTTCAAGTGTCTGACCTGCGACGCCTCGTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGCGACACTAACCGGTGTGACAATCGTCCGCAACGCGACTTGGACGATGAAGAGCCCAGCCAGGACTCACAGCTGAGCACCATTTACCATCTGGCGTGTCCGCAGTGCGGCGATGACTTCAACACCCCCAGTCGGAAGCAGTGGCGCGATCACATTAACATCCTTCACGGCCTGACCGCGCTGGACCTGCTGCACATGCACAAGGTGGATGGCGCTGAGGATCTGTATCGCTGCCAGGACTGCAACGAGGAGCTGCAGACGAACCGGCAGTGGGTGCTGCAATATCACCGCTTCCAGCATCTTCCACAGCCGGCCTACATCCGCTGCCAGCTGTGCGAGCAGAGCAGTGATCGGGATGCGTCTGTGGGATCCGGCCTGCACAGTCTCcgggagctgcagcagcatcttCGCAAGCATCATCCCACAACGGTCGGCGAGAACGAGATGCAGATACTCCGCGAACAGATTGcccaggaggagaaggagcaggaggagacCGTGGGCCAGGCCGCAGATGAAGAGGACAACCAGACGGGCCAGGATTCAGGGCCCTAcatgccgctgccgccgcatTTATTGGACGACGGAGACGACATGGAATTTGAGGACCAGTATTTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSELDDGEPEGGGEGELLDGGEDGAQYGNGNGDLLDDTAILEAGEGVEDLLDGEDDEREEDDEDGSMEKKSKGPEPDDDALFDFELEPIVSIGESSPASVLAPAGPMRPSLQRHSLPPPNPSRLPGRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMQREKSFLEGDHDLDHIEVRNELLEPDVDESGGMVHHHPPRLAEETPQKKRSGGGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTEHSELVRHLLKHHHLETLMSEEPGQEGEEDAAQTMDGGNEFEDNGHGEGNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCEARKSGGGAAPPLPMLTTPKQPRKQIVTVANETYEIIYLDDVEQSSLEEENDFGEQMLADEDDYPVVQPPQQRQLPAPQPRPPSQITQQRYKCVHCSTLFPTQMAVRVHISEKHSRKPHQAGRRHRLMISNSGGADSGLTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPLMVTKPMKAYNRFKDGDKEKIPIPTPAPAAGSPPGCSSSASLAVPAAAPVVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRDLDDEEPSQDSQLSTIYHLACPQCGDDFNTPSRKQWRDHINILHGLTALDLLHMHKVDGAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQSSDRDASVGSGLHSLRELQQHLRKHHPTTVGENEMQILREQIAQEEKEQEETVGQAADEEDNQTGQDSGPYMPLPPHLLDDGDDMEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00541377;
90% Identity: iTF_00541377;
80% Identity: -