Basic Information

Insect: Drosophila vulcana
Gene Symbol: -
Assembly: GCA_008042555.1
Location: VNJP01007500.1:63576-67495[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7e-05 0.0095 16.9 0.4 1 23 164 187 164 187 0.96

2 14 0.0014 0.19 12.9 3.1 2 23 236 258 232 258 0.90

3 14 0.006 0.81 10.9 0.8 1 23 353 376 353 376 0.93

4 14 0.042 5.7 8.2 2.8 2 23 425 447 424 448 0.95

5 14 0.00054 0.073 14.1 0.4 1 23 517 540 517 540 0.92

6 14 1.6 2.1e+02 3.2 0.1 2 14 559 571 558 583 0.85

7 14 0.00055 0.074 14.1 3.3 2 23 591 613 591 613 0.96

8 14 0.041 5.6 8.2 0.8 1 23 707 730 707 730 0.95

9 14 4e-05 0.0054 17.7 0.3 1 23 765 788 765 788 0.93

10 14 0.0034 0.46 11.6 1.5 2 23 838 860 837 860 0.95

11 14 0.015 2 9.6 1.8 1 23 962 985 962 985 0.91

12 14 0.0017 0.23 12.6 1.4 1 21 1037 1057 1037 1058 0.95

13 14 0.92 1.2e+02 4.0 0.1 3 23 1090 1113 1088 1113 0.82

14 14 3.4 4.6e+02 2.2 0.3 1 11 1133 1143 1133 1157 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7e-05	0.0095	16.9	0.4	1	23	164	187	164	187	0.96
2	14	0.0014	0.19	12.9	3.1	2	23	236	258	232	258	0.90
3	14	0.006	0.81	10.9	0.8	1	23	353	376	353	376	0.93
4	14	0.042	5.7	8.2	2.8	2	23	425	447	424	448	0.95
5	14	0.00054	0.073	14.1	0.4	1	23	517	540	517	540	0.92
6	14	1.6	2.1e+02	3.2	0.1	2	14	559	571	558	583	0.85
7	14	0.00055	0.074	14.1	3.3	2	23	591	613	591	613	0.96
8	14	0.041	5.6	8.2	0.8	1	23	707	730	707	730	0.95
9	14	4e-05	0.0054	17.7	0.3	1	23	765	788	765	788	0.93
10	14	0.0034	0.46	11.6	1.5	2	23	838	860	837	860	0.95
11	14	0.015	2	9.6	1.8	1	23	962	985	962	985	0.91
12	14	0.0017	0.23	12.6	1.4	1	21	1037	1057	1037	1058	0.95
13	14	0.92	1.2e+02	4.0	0.1	3	23	1090	1113	1088	1113	0.82
14	14	3.4	4.6e+02	2.2	0.3	1	11	1133	1143	1133	1157	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCAATGTTCTCCTCAGAGTTTGAGGACGGCGAGCAAGAAGCGGGTGGCGAGGGAGAGCTGCTGGAGGGTGGTGAGGATGGGGCGCAATACGGCAACGGAAATGGCGACATACTCGATGACACGGCGATCCTGGAGGCTGGAGATGGTGTAGACGACCTGCTAGATGGCGAGGACGATGAGCGGGAGGAGAACGACGAAGATGGCACGGAAAAGGTGTCAAAGGGACCGGAACCGGACGACGATGCCCTCTTTGACTTCGAACTGGAGCCGATTGTGAGTATTGGCGAGCCGTCGCCGGCTTCGGTTCTTGCGCCCGCTGGTCCGATGGGCGCCCAAGTGCGCCCAGCTCTGCAGCGGCATAAACTGCCCACCCGACCGATTGGGTTTCCCGTGCGTCCCACCACCTCACAGATCAATGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATCTGCCCAGCCTGTGGCGGAGAGTTCCGGCAGCAGGATCACTGGAAACGGCACATGAATCAAATCCATAGGTACAACACCCTGCGGGGCCTCAACTTTGCGCCGCTGGACAAGCTATATCAGCGCTGCAAGGAGTGCCACAAGCGAATCGCTATGCACAGCCGGGAGAATCTGCTGAAACACAAGTTCACCCACCTGCCGTTCCGGTGCACCAAGTGCTACATTTGCAAGCGGGAGTATAAATACAGaCAAGATCTAATGGTGCACCTGCGCATGGTCCACTGTGACGAAGTGGTGTCCATGATGCGGGAAGGTTACAATGCTGCTGGACGCAAAACCCGTGTCCGAGAGTCTCGCACTGAACAAATGCAGCGGGAGAAGAGTTTTCTAGAGGATGAGGATCTAGATCACATCGAGGTGCGTAACGAGCTGCTCGAACCGGATGTTGATGAGTCCGGCGGCATGGAGCATCATCCGGCGTTGCTGGTAGAGGAGACGCCCCATAAGAAGCGACCCGGCGGCAGTGGCGGTGAAGCCGCCGAGCTGTGCGAAGACTACATCCACTACATGTGCCCTGACTGCGGCACCGAGTGCGACACCCACGCCCAGTGGAGCCAGCACATTGAGTTTGTTCACGACTATGTCAGCCGGCGTGGCCTCAACTTTCGGAGTGTCGATATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTAACACCCAACACCATCAAGTCGCTGCGCGCCCACAAATTCAGTCACTTGTCGCATCCCGAGTGGCTTCGCTGCAAGCTCTGCTACAAGGGCTACACGGAACATCCGGAACTGGTTAGGCATTTGCTGAAAAATCATCATCTAGAGACGCTGATGTCGGAGGACACTGGCCAGGAAGAGGAGAATGATGCCTCACTGACCATAGATGAAAGAAGTGAATGCGCAGACAATGGCAATGGCGAGGGAAACGGCGCCGCCTTGGACGAGGATTCACCTTACTTTGAAGATGCTCCCCGACGCGGCGGTCGTATTAGCAGCGATGACATTTTCGAACCGCACATTGACTACCTCTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAAAAGCACTGGCGCACCCATGTGGTCATGGCGCACAGCATGAACGATCTTTCCAAGCTGAATTTCGAGATGATCAACGAACGGCAGCTGAAATGCACCGAATGCGACAAGATTATCACGAATGCGTATGGCATACAGAATGCCCAGCAGCACAGGATCACTCATCTGCCATTCAAGGCGTATGCCAGATGCCGCAAGTGCCACAAGTCGTACACTGACCGAAAAGGTCTCGTCAAGCATCTGGCTACCTATCACCGCATAGGCTGTGATCCTAGGAAGTCTGGAGCTGGTGCAGCGCCACCTTTACCCATGCTAACTACACCCAAGCAGCCCCGCAAGCAGATCGTCACAGTGGCCAATGAGACTTACGAGATTATTTACCTGGACGATGTGGAGAGCAGCTTGGATGAGGAGAATGACTTTGGGGAGCAGATGCTCGCTGACGAGGACGATTATCCGGTTATCCAGGCACCGCAACAGCGTCAGGTGCCGACTCCAACACGACACACCTCCTCGCAGAACTCGCAGCAACGCTACAAGTGTGTCCACTGCAGCACCCTCTTCCCCACCCAGGTGGCCGTGCGTATGCACATCAGCGAGAAGCATTGCCGGAAGCCGCATCCGACGGGTAGGAGGCATCGCCATTTTGTTGCCAATTCTGGTAGTGGAGCAGACTCGGGCCTTACCACCGTAGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAACGAGGAGCACAACTTTGACAAGCGAAACTACCTGAATATGCGGCAGTTAGACAAATATCGCTATCAGTGCACACAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTGCAGGACCACCATTTCCGTCATCTGCCATACCGCCTGTATCTCAAGTGCTTAGTCTGTGGCACCTGTTATAACCACAAGCCGAACATAGCGGCACATCTCAGGGCGCGACACAACATCTACGACAAAGAGGCGCACGTGATCGTCACCAAGCCGATTAAAACCTATAGTCGGTTCAAGGATGGGGATAGAGGGAAGATCTCTTTACCCATTCCGGCTCCGGCAGCAGGATCTCCAcccggctgctcctcctcctccgcctcctcctcagctgttgttgttgctgctgctgctgtgcccgTGGTTAGTCGAACTCTTAAACCCCAACCCGGTGACCTGCCCACACGACCCGCTGGCCTCAACACCCTGGAGGACAGCATCTCGTACCACAATGCCGTAGATATGGATTTCATTACGTACTTCTGTCCGAAATGCAATCAGAATTTCGATTCGCATGCCTTCTGGCGCAAGCACATCGTCGAGCAGCACAACTTCAACAGCCGCGAGGGTCTGAACTTCCGGCAGATTGACAACCATCACTACCTGTGCCTGGAGTGTTACAAGCGCGTCACGGTGACCCACACCAAGGGCGCCATTGGTCAGCTGCAGTCGCACAAATTCCGGCATCTTCCCCATCGCTCCTTCAAGTGTCTGACCTGCGACGCCTCGTTTGTGCGCAAGcaaatgttttttaagcaTCTGAATCGCGACACCAATCGGTGTGACAATCGTCCGCAACGCGAATTGGACGATGAAGAGCCCAGCCAGGACGCTCAGCTGACCACCATTTATCACTTGGCGTGTCCGCAGTGCGGCGATGACTTTAGCACTCCCAGTCGGAAGCAGTGGCGCGATCACATTAACGTCTTTCACGGCCTCACCGCCCTGGATCTGCTGCACATGAACAAGGTGGATGGCGCGGAGGATCTCTATCGCTGCCAGGACTGCAACGAGGAGCTGCAGACGAACCGGCAGTGGGTGCTGCAATACCATCGCTTTCAGCATCTGCCACAGCCGGCCTACATTCGCTGCCAGCTGTGCGAGCAGAGCACAGAGCGAGATGCTGCAGTGGCATCTGGGATGCATAGTCTACgcgagctgcagcagcatctgcGCAAGCATCATGCCACAACGGTGGGTGAGAACGAAATGCAGCTGCTCCGCGAACAGATTGcccaggaggagaaggagcaggatgaGACAGTGGGACAGTTGGCTGCAGATGAAGAGGACAACCAGGCGGGTCAGGACTCGGGACCCTACATGCCGCTTCCGCCGCATTTATTGGACGACGGAGACGATGTGGAGTTTGAGGACCAGTATTTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSEFEDGEQEAGGEGELLEGGEDGAQYGNGNGDILDDTAILEAGDGVDDLLDGEDDEREENDEDGTEKVSKGPEPDDDALFDFELEPIVSIGEPSPASVLAPAGPMGAQVRPALQRHKLPTRPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVSMMREGYNAAGRKTRVRESRTEQMQREKSFLEDEDLDHIEVRNELLEPDVDESGGMEHHPALLVEETPHKKRPGGSGGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTEHPELVRHLLKNHHLETLMSEDTGQEEENDASLTIDERSECADNGNGEGNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDPRKSGAGAAPPLPMLTTPKQPRKQIVTVANETYEIIYLDDVESSLDEENDFGEQMLADEDDYPVIQAPQQRQVPTPTRHTSSQNSQQRYKCVHCSTLFPTQVAVRMHISEKHCRKPHPTGRRHRHFVANSGSGADSGLTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIYDKEAHVIVTKPIKTYSRFKDGDRGKISLPIPAPAAGSPPGCSSSSASSSAVVVAAAAVPVVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSQDAQLTTIYHLACPQCGDDFSTPSRKQWRDHINVFHGLTALDLLHMNKVDGAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQSTERDAAVASGMHSLRELQQHLRKHHATTVGENEMQLLREQIAQEEKEQDETVGQLAADEEDNQAGQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00613098;
90% Identity: iTF_00541377;
80% Identity: -