Basic Information

Insect: Drosophila serrata
Gene Symbol: -
Assembly: GCA_002093755.1
Location: NW:2658595-2663982[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.6e-05 0.0049 16.9 0.4 1 23 172 195 172 195 0.96

2 14 0.0015 0.097 12.9 3.1 2 23 244 266 240 266 0.90

3 14 0.0065 0.42 10.9 0.8 1 23 361 384 361 384 0.93

4 14 0.0036 0.23 11.7 2.9 2 23 433 454 432 455 0.94

5 14 0.00059 0.038 14.1 0.4 1 23 524 547 524 547 0.92

6 14 1.7 1.1e+02 3.2 0.1 2 14 566 578 565 590 0.85

7 14 0.00059 0.038 14.1 3.3 2 23 598 620 598 620 0.96

8 14 0.045 2.9 8.2 0.8 1 23 714 737 714 737 0.95

9 14 4.4e-05 0.0028 17.7 0.3 1 23 771 794 771 794 0.93

10 14 0.0037 0.24 11.6 1.5 2 23 844 866 843 866 0.95

11 14 0.016 1 9.6 1.8 1 23 962 985 962 985 0.91

12 14 0.0018 0.12 12.6 1.4 1 21 1037 1057 1037 1058 0.95

13 14 1.2 76 3.8 0.1 3 23 1090 1113 1088 1113 0.86

14 14 3.7 2.4e+02 2.2 0.3 1 11 1133 1143 1133 1157 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.6e-05	0.0049	16.9	0.4	1	23	172	195	172	195	0.96
2	14	0.0015	0.097	12.9	3.1	2	23	244	266	240	266	0.90
3	14	0.0065	0.42	10.9	0.8	1	23	361	384	361	384	0.93
4	14	0.0036	0.23	11.7	2.9	2	23	433	454	432	455	0.94
5	14	0.00059	0.038	14.1	0.4	1	23	524	547	524	547	0.92
6	14	1.7	1.1e+02	3.2	0.1	2	14	566	578	565	590	0.85
7	14	0.00059	0.038	14.1	3.3	2	23	598	620	598	620	0.96
8	14	0.045	2.9	8.2	0.8	1	23	714	737	714	737	0.95
9	14	4.4e-05	0.0028	17.7	0.3	1	23	771	794	771	794	0.93
10	14	0.0037	0.24	11.6	1.5	2	23	844	866	843	866	0.95
11	14	0.016	1	9.6	1.8	1	23	962	985	962	985	0.91
12	14	0.0018	0.12	12.6	1.4	1	21	1037	1057	1037	1058	0.95
13	14	1.2	76	3.8	0.1	3	23	1090	1113	1088	1113	0.86
14	14	3.7	2.4e+02	2.2	0.3	1	11	1133	1143	1133	1157	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCGATGTTCTCCTCGGAGTTCGAGGACGGAGAGCCGGAAGGGGGCGGCGAGGGAGAGCAGCTGGCGGGTGGAGAGGATGGGGCGCAGTACGGCAACGGTAATGGCGACTTTATCGACGATACGGCCATCCTGGAGGCTGGAGATGGTGTAGACGACCTGCTAGATGGCGAGGATGAGGAGAGGGAAGAGGACGACGAAGGTGGCACTAAAAAGGCGTCGAAGGGACCGGAACCGGACGACGATGCGCTCTTCGATTTCGAGCTGGAGCCAATTGTGAGTATTGGTGAGTCGTCGCCGGCTTCGGTTTTGGCGCCCGCCGGTCCGATGGGTGCCCGAGTTCGCCCAGCCCTGCAACGGCAATCACTGCCAGCCCTAAGTCGGCCGCGATCCGATATGCGACCCATTGGATTTCCCGTGCGTCCCACCACTTCCCAGATCAATGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTAGTGTACATCTGCCCAGCCTGTGGCGGAGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAATCAAATCCATAGGTACAACACCCTTCGGGGCCTTAACTTTGCGCCGCTGGACAAGCTCTATCAGCGCTGCAAGGAATGCCACAAACGAATCGCTATGCACAGCCGGGAGAACCTGCTAAAGCACAAGTTCACACACCTGCCGTTTCGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGGCAAGATCTAATGGTGCACCTCCGCATGGTACACTGCGACGAAGTGGTGGCCATGATGCGGGAAGGTTACAATGCTGCCGGACGGAAAACCCGTGTCCGAGAGTCACGTACAGAGCAAATGAAGCGGGAGAAGAGTTTTCTCGAGGATGAGGACCTAGATCACATCGAGGTGCGAAACGAGCTGCTCGAACCGGATGTTGATGAGTCCGGCGGCATGGGTCAACATCCGACGCAGGTGGTGGAGGAGACGCCCCAAAAGAAGCGACCCGGCGGCAGTGGCGGAGAAGCCGCTGAGCTGTGCGAGGACTACATCCACTACATGTGCCCTGACTGCGGCACTGAGTGCGATACCCACGCCCAGTGGAGTCAGCACATTGAATTTGTCCACGACTATGTCAGCAGGCGTGGCCTCAACTTTCGGAGTGTCGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTATAACACCCAACACCATCAAGTCGCTTCGTGCCCACAAATTCAGTCACTTGTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGATCATCCGGAATTGGTTAGGCATTTGCTAAAGCATCATCATCTGGAGACCCTAATGTCAGAGGACCCTGGCCAGGAAGAGGGGGATGCGTCTCTGGCCATCGATGGGGGGAATGAATGTGAAGACAACGGCAATGGCGAGGGAAACGGCGCGGCATTGGACGAGGATTCACCCTACTTTGAAGATGCCCCCCGTCGCGGCGGTCGAATAAGCAGCGATGACATTTACGAACCGCACATCGACTACCTCTGCCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTCATGGCGCACAGCATGAACGATTTGTCCAAGCTGAACTTTGAGATGATCAACGAACGGCAGCTAAAGTGCACCGAATGCGATAAGATCATCACAAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATTACCCATCTGCCATTCAAGGCATATGCCAGATGCCGCAAGTGCCACAAGTCCTATACGGACCGAAAGGGTCTCGTCAAGCATCTTGCCACCTATCACCGCATCGGCTGTGATTCTCGGAAGTCTGGTGGAGGTGCAGCACCACCGTCACCCATGGTAACTACTCCAAAGCAGCCCCGCAAGCAGATCGTCACCGTGGCCAATGAGACCTACGAGATAATCTACCTGGACGATGTGGAGCAGACCAGCTTGGATGAGGAGAATGACTTTGGGGAACAGATGCTTGCTGACGAGGACGATTATCCGGTTATTCAGCCACCGCAACAGCGTCAGGTGCCGCCTCCACCACGACCTGCCCCGCAAAACACTCAGCACCGCTACAAGTGCGTCCACTGCAGCACTCTCTTCCCCACTCAGGTGGCCGTGCGGATGCACATAAGCGAGAAGCATTGCCGGAAGCCTCATCAGGTGGGCAGAAGACATCGTCATTCGCTTTCGAATCCCGGTGGAGCAGACTCTGGTCTTACCACAGTGGAACAGAATTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAAACGCAGTACGAGTGGCGACGTCATATTAACGAGGAGCACAACTTTGACAAGCGAAACTACCTGAACATGCGACAGCTGGACAAGTACCGCTACCAGTGCACACAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTGCAGGACCATCACTTCCGCCATCTGCCATATCGCCTGTACCTCAAGTGCTTGGTCTGTGGAACCTGCTACAACCACAAACCGAACATTGCAGCACATCTCAGGGCGCGCCACAACATCTTCGACAAGGAGGCGCCCCTAATGGCTACCAAGCCAATGAAAGTCTACAGTCGTTTCAAGGATGGGGATAGAGAGAAGATCCCTGTACCCCCTCCCGTTCCGGCAGCAAGATCTCCACCCGGCTGCTCCACTTCTTCCGCAGCGGTTGTTGCTGCCGTGCCTGTGGTCAATCGCACGCTTAAACCCCAACCCGGTGACCTGCCCACACGACCCGCTGGCCTGAATACCCTGGAGGACAGCATCTCGTACCACAATGCCGTAGATATGGACTTCATCACGTACTTCTGTCCGAAGTGCAACCAGAACTTTGACTCGCACGCATTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGACTGAACTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACGGTGACCCACACCAAGGGCGCCATTGGACAGCTGCAGTCGCACAAGTTCCGGCATCTTCCCCATCGCTCCTTCAAGTGTCTGACCTGCGACGCCTCGTTTGTGCGTAAGCAAATGTTCTTCAAGCATCTGAATCGTGACACCAACCGGTGTGATAATCGTCCGCAACGCGAGTTGGACGATGAAGAGCCCAGCCAGGACTCTCAGCTGAACACCATTTACCACCTGGCTTGTCCGCAGTGCGGCGATGACTTCAACACCTCCAGTCGGAAGCAGTGGCGCGATCACATTAACGTGGTTCATGGCTTAACCGCGCTGGACCTGCTGCACATGAACAAGGTGGATGGCGCGGAGGATCTGTATCGCTGTCAGGACTGCAACGAAGAGCTGCAGACGAACCGGCAGTGGGTGCTGCAATACCACCGCTTCCAGCATCTCCCACAGCCGGCCTACATCCGCTGCCAGCTGTGCGAGCAGAACAGTGAGCGGGATGCGACAGTGGGATCCGGGATGCACAGTCTACGtgagctgcagcagcatctTCGCAAGCATCATCCCACAACGGTGGGCGAGAACGAGATGCAGATGCTTCGCGAACAGATTGCCCAAGAAGAAAAGGAGCAGGAGGTGACCGTGGGCCAGGCCGCAGATGAAGAGGACAACCAGATGGGCCAGGACTCCGGCCCATATATGCCGCTTCCGCCGCATTTATTGGATGATGGAGACGACGTAGAGTTTGAGGACCAGTATTTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSEFEDGEPEGGGEGEQLAGGEDGAQYGNGNGDFIDDTAILEAGDGVDDLLDGEDEEREEDDEGGTKKASKGPEPDDDALFDFELEPIVSIGESSPASVLAPAGPMGARVRPALQRQSLPALSRPRSDMRPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMKREKSFLEDEDLDHIEVRNELLEPDVDESGGMGQHPTQVVEETPQKKRPGGSGGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIITPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTDHPELVRHLLKHHHLETLMSEDPGQEEGDASLAIDGGNECEDNGNGEGNGAALDEDSPYFEDAPRRGGRISSDDIYEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDSRKSGGGAAPPSPMVTTPKQPRKQIVTVANETYEIIYLDDVEQTSLDEENDFGEQMLADEDDYPVIQPPQQRQVPPPPRPAPQNTQHRYKCVHCSTLFPTQVAVRMHISEKHCRKPHQVGRRHRHSLSNPGGADSGLTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDKEAPLMATKPMKVYSRFKDGDREKIPVPPPVPAARSPPGCSTSSAAVVAAVPVVNRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSQDSQLNTIYHLACPQCGDDFNTSSRKQWRDHINVVHGLTALDLLHMNKVDGAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQNSERDATVGSGMHSLRELQQHLRKHHPTTVGENEMQMLREQIAQEEKEQEVTVGQAADEEDNQMGQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491795;
90% Identity: iTF_00541377;
80% Identity: -