Basic Information

Insect: Drosophila truncata
Gene Symbol: -
Assembly: GCA_008042515.1
Location: VNJQ01000304.1:7445-11388[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.5e-05 0.0065 16.9 0.4 1 23 169 192 169 192 0.96

2 14 0.0031 0.27 11.8 3.0 2 23 241 263 237 263 0.90

3 14 0.0064 0.56 10.9 0.8 1 23 361 384 361 384 0.93

4 14 0.0043 0.38 11.4 3.8 2 23 433 454 432 455 0.94

5 14 0.00057 0.05 14.1 0.4 1 23 526 549 526 549 0.92

6 14 1.7 1.5e+02 3.2 0.1 2 14 568 580 567 592 0.85

7 14 0.00058 0.051 14.1 3.3 2 23 600 622 600 622 0.96

8 14 0.025 2.2 9.0 0.6 1 23 716 739 716 739 0.95

9 14 4.3e-05 0.0037 17.7 0.3 1 23 774 797 774 797 0.93

10 14 0.0036 0.32 11.6 1.5 2 23 847 869 846 869 0.95

11 14 0.016 1.4 9.6 1.8 1 23 969 992 969 992 0.91

12 14 0.0018 0.16 12.6 1.4 1 21 1044 1064 1044 1065 0.95

13 14 3.1 2.7e+02 2.4 0.1 3 23 1097 1120 1095 1120 0.74

14 14 3.6 3.2e+02 2.2 0.3 1 11 1140 1150 1140 1164 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.5e-05	0.0065	16.9	0.4	1	23	169	192	169	192	0.96
2	14	0.0031	0.27	11.8	3.0	2	23	241	263	237	263	0.90
3	14	0.0064	0.56	10.9	0.8	1	23	361	384	361	384	0.93
4	14	0.0043	0.38	11.4	3.8	2	23	433	454	432	455	0.94
5	14	0.00057	0.05	14.1	0.4	1	23	526	549	526	549	0.92
6	14	1.7	1.5e+02	3.2	0.1	2	14	568	580	567	592	0.85
7	14	0.00058	0.051	14.1	3.3	2	23	600	622	600	622	0.96
8	14	0.025	2.2	9.0	0.6	1	23	716	739	716	739	0.95
9	14	4.3e-05	0.0037	17.7	0.3	1	23	774	797	774	797	0.93
10	14	0.0036	0.32	11.6	1.5	2	23	847	869	846	869	0.95
11	14	0.016	1.4	9.6	1.8	1	23	969	992	969	992	0.91
12	14	0.0018	0.16	12.6	1.4	1	21	1044	1064	1044	1065	0.95
13	14	3.1	2.7e+02	2.4	0.1	3	23	1097	1120	1095	1120	0.74
14	14	3.6	3.2e+02	2.2	0.3	1	11	1140	1150	1140	1164	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCGATGTTCTCCTCTGAGCTCGAGGAGGGTGACGGCGAGGCAGAGCTGCTAGAGGGTGGTGACGATGCGGCGCAGtatggcaatggaaatggcgACTTACTCGACGACACGGCGATCCTGGAGGCTGGAGAGGGCGTAGATGACCTGCTAGATGGCGAGGATGATGAGCgggaggaggacgacgacgagaaTGCCATGGAAAAGAAGCCAAAGGGACCGGAACCGGACGACGATGCCCTCTTCGACTTTGAGCTGGAGCCAATTGTTAGCATTGGGGAGTCGTCACCGGCTTCGCTTCTAGCGCCCGCCGGTCCTACGAGTGCCCAAGTGCGCCCAGCCCTGCAGCGCCATTCACTGCCCCCGCTGACTCGTCCCCGGTCCGATATGCGACCCATTGGCTTTCCCGTGCGTCCCACCACTTCACAGATCAATGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATTTGCCCAGCCTGTGGCGGAGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACCCTTCGGGGCCTCAACTTTGCACCGCTGGACAAGCTGTATCAGCGCTGCAAGGAGTGCCACAAGCGCATAGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACGCACCTGCCCTTCCGGTGCACCAAGTGCTACATCTGCAGGCGGGAGTACAAATACAGGCAAGATCTTATGGTGCACCTGCGCATGGTACACTGCGACGAAGTGGTGGCCATGATGCGGGAAGGTTACAATGCTGCCGGACGCAAAACCCGTGTCCGAGAGTCGCGTACAGAGCAAATGCAGCGGGAGAAGAGTTTTCTCGAGGATGACGAAGACCTCACAGATCACATCGAGGTGCGCAATGAGCTGCTCGAACCGGATCTTGATGAGTCGGGGGGCATGGTGCATCATCCGCCGCTGCTGGTAGAGGAAACGACGCCTCAAAAGAAACGACACGGCGGCAGTGGCGGAGAAGCCGCAGAGCTGTGCGAGGATTACATTCACTACATGTGCCCCGACTGCGGCACAGAGTGCGACACCCATGCCCAGTGGAGCCAGCACATAGAGTTTGTCCACGACTATGTCAGCCGGCGTGGCCTCAACTTTCGGAGTGTCGACATGCAAATGCAGTGCCTGGAATGCAAGAAGATTGTCACTCCCAACACCATCAAGTCACTGCGCGCCCATAAATTCAGTCATTTGTCGCATCCCGAGTGGCTGCGCTGCAAACTCTGCTACAAGGGCTACACGGAGCATTCGGAACTGGTTAGGCATCTGCTGAAGCATCATCATTTGGAGACTCTGATGTCGGACCGGGATGCGGGACAGGAAGAGGAGGATGCCTCACATACCCTGGATGGGGGAAATGAATTCGAAGACAATGGCAATGGTGAAATGGGAAACGGCGCCGCCTTGGATGAGGATTCACCCTACTTTGAAGACGCCCCCCGACGCGGCGGTCGTATTAGCAGCGATGACATTTTTGAACCGCACATCGATTACCTTTGTCCACAGTGCGGCAAGGAGTTCATCGAGAAGAAGCATTGGCGCACTCACGTGGTCATGGCGCACAGCATGAACGATCTGTCCAAGCTGAATTTCGAAATGATCAACGAACGGCAGCTAAAATGCACGGAATGCGACAAAATCATCACGAATGCGTATGGAATACAGAATGCCCAGCAGCACAGGATTACGCATTTGCCGTTTAAAGCGTATGCCAGATGCCGCAAGTGCCACAAGTCCTACACGGACCGAAAGGGTCTCGTTAAGCATCTAGCCACCTATCACCGCATCGGCTGTGATGTTCGAAAGTCTGGCGGGGGTGTAGCTCCACCTTTACCCATGCTAACTACCCCCAAGCAGCCACGCAAGCAGATCGTCACCGTGGCCAATGAGACCTACGAGATTATCTACTTGGACGATGTGGATCAGGGAAGCTTGGAGGAGGATAATGACTTTGGGGAGCAGATGCTCGCTGACGAGGATGATTATCCGGTTATCCAGCCACCGCAACAGCATCAGGTGCCGCCTCCACCACGACCCCCGCCGCAGAACTCGCAGCAGCGTTACAAATGCGTCCACTGCAGCACTCTCTTCCCCACCCAGGTGGCCGTGCGGGTGCACATCAGCGAGAAGCATAGCCGGAAGCCCCATCAGACGGGGAGGAGGCATCGCCTTATGATTTCAAATGCCGGTGGAGCGGTGGACTCAGGGCTTAACACAGTGGAGCAGAACTACATCTTCCTGTGCCCTTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAACGAGGAGCACAACTTTGATAAGCGAAACTTCCTGAACATGCGGCAGTTGGACAAGTATCGCTACCAGTGCACGCAGTGCAAGGACATAGTGTGCAATTCGAAGCTGAAGGGTCTGCAGGACCATCACTTCCGTCACCTGCCATACCGACTGTATCTCAAGTGCTTGGTTTGCGGCACCTGCTATAACCACAAACCGAACATAGCGGCACATCTCAGGGCGAGACACAACATCTTCGACAGGGAGACGCCTGCGATGGTCACCAAGCCGATAAAAACCTACAGCCGCTTCAAGGATGGGGATAAAGAGAAGATCCCGCTACCTGTTCCCGCTCCAGCAGCAGGTTCTCCACCCGGTtgctcctcatcatcatcctctgcagctgttactgctgctgctgctgcgcctgtGGTCAGTCGCACTCTTAAACCCCAACCCGGTGACCTGCCCACGCGACCCGCTGGCCTGAACACCCTGGAGGACAGCATTTCGTACCACAATGCCGTAGACATGGACTTTATCACGTACTTTTGCCCAAAGTGCAACCAGAACTTCGACTCGCATGCCTTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTTAATAGCCGCGAGGGTCTGAACTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACAGTGACCCACACGAAGGGCGCCATTGGTCAGCTGCAGTCGCACAAGTTCCGGCATCTTCCCCATCGCTCCTTCAAGTGTCTGACCTGCGATGCCTCGTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGCGACACTAATCGGTGTGACAATCGTCCGCAACACGAGTTGGACGATGAAGAGCCCAGCCAGGACTCACAGCTGAGCACCATTTACCACCTGGCGTGTCCGCAGTGCGGCGATGACTTCAACACGCCCAGCCGGAAGCAATGGCGCGATCACATTAACATCCTTCATGGCCTGACCGCGCTGGACCTGCTGCACATGAACAAGGTGGAGGGCGCCGAGGATCTGTATCGCTGCCAGGACTGCAACGAGGAGCTGCAAACGAACCGGCAGTGGGTGCTGCAATACCATCGCTTCCAGCATCTTCCACAGCCGGCCTACATTCGCTGCCAGCTGTGCGAACAGAGCAGTGAACGTGATGCGGCAGTGGGATCAGGGCTGCATAGCTTACgtgagctgcagcagcatctcCGCAAGCATCATGCCACAACGGTGGGCAAGAATGAGATGCAAATGCTACGCGAACAGATTGCCCAGGAGgaaaaggagcaggaggagaccGTGGGCCAGGCCGCAACTGAAGAAGACAACGAAACGGGCCAGGACTCAGGGCCCTACATGCCGCTTCCGCCGCATTTACTGGACGATGGAGACGACATGGAATTTGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSELEEGDGEAELLEGGDDAAQYGNGNGDLLDDTAILEAGEGVDDLLDGEDDEREEDDDENAMEKKPKGPEPDDDALFDFELEPIVSIGESSPASLLAPAGPTSAQVRPALQRHSLPPLTRPRSDMRPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICRREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMQREKSFLEDDEDLTDHIEVRNELLEPDLDESGGMVHHPPLLVEETTPQKKRHGGSGGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTEHSELVRHLLKHHHLETLMSDRDAGQEEEDASHTLDGGNEFEDNGNGEMGNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDVRKSGGGVAPPLPMLTTPKQPRKQIVTVANETYEIIYLDDVDQGSLEEDNDFGEQMLADEDDYPVIQPPQQHQVPPPPRPPPQNSQQRYKCVHCSTLFPTQVAVRVHISEKHSRKPHQTGRRHRLMISNAGGAVDSGLNTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNFLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPAMVTKPIKTYSRFKDGDKEKIPLPVPAPAAGSPPGCSSSSSSAAVTAAAAAPVVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQHELDDEEPSQDSQLSTIYHLACPQCGDDFNTPSRKQWRDHINILHGLTALDLLHMNKVEGAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQSSERDAAVGSGLHSLRELQQHLRKHHATTVGKNEMQMLREQIAQEEKEQEETVGQAATEEDNETGQDSGPYMPLPPHLLDDGDDMEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00617915; iTF_00490365;
90% Identity: iTF_00541377;
80% Identity: -