Basic Information

Insect: Drosophila seguyi
Gene Symbol: -
Assembly: GCA_008042675.1
Location: VNJU01009527.1:9844-13763[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.9e-05 0.0058 16.9 0.4 1 23 170 193 170 193 0.96

2 14 0.0016 0.11 12.9 3.1 2 23 242 264 238 264 0.90

3 14 0.0068 0.49 10.9 0.8 1 23 359 382 359 382 0.93

4 14 0.016 1.2 9.7 1.1 2 23 431 453 430 453 0.95

5 14 0.00061 0.044 14.2 0.4 1 23 522 545 522 545 0.92

6 14 1.8 1.3e+02 3.2 0.1 2 14 564 576 563 588 0.85

7 14 0.00062 0.045 14.1 3.3 2 23 596 618 596 618 0.96

8 14 0.047 3.4 8.2 0.8 1 23 710 733 710 733 0.95

9 14 4.5e-05 0.0033 17.7 0.3 1 23 767 790 767 790 0.93

10 14 0.0038 0.28 11.6 1.5 2 23 840 862 839 862 0.95

11 14 0.017 1.2 9.6 1.8 1 23 961 984 961 984 0.91

12 14 0.0019 0.14 12.6 1.4 1 21 1036 1056 1036 1057 0.95

13 14 3.1 2.3e+02 2.5 0.1 3 23 1089 1112 1087 1112 0.80

14 14 3.8 2.8e+02 2.2 0.3 1 11 1132 1142 1132 1156 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.9e-05	0.0058	16.9	0.4	1	23	170	193	170	193	0.96
2	14	0.0016	0.11	12.9	3.1	2	23	242	264	238	264	0.90
3	14	0.0068	0.49	10.9	0.8	1	23	359	382	359	382	0.93
4	14	0.016	1.2	9.7	1.1	2	23	431	453	430	453	0.95
5	14	0.00061	0.044	14.2	0.4	1	23	522	545	522	545	0.92
6	14	1.8	1.3e+02	3.2	0.1	2	14	564	576	563	588	0.85
7	14	0.00062	0.045	14.1	3.3	2	23	596	618	596	618	0.96
8	14	0.047	3.4	8.2	0.8	1	23	710	733	710	733	0.95
9	14	4.5e-05	0.0033	17.7	0.3	1	23	767	790	767	790	0.93
10	14	0.0038	0.28	11.6	1.5	2	23	840	862	839	862	0.95
11	14	0.017	1.2	9.6	1.8	1	23	961	984	961	984	0.91
12	14	0.0019	0.14	12.6	1.4	1	21	1036	1056	1036	1057	0.95
13	14	3.1	2.3e+02	2.5	0.1	3	23	1089	1112	1087	1112	0.80
14	14	3.8	2.8e+02	2.2	0.3	1	11	1132	1142	1132	1156	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCGATGTTCTCCTCAGAATTCGAGGAGCCGGAAGGGGGTGGCGAGGTAGAGATGCAGGAGGGTGGTGAGGATGGGGCGCAGTACGGCAACGGAAATGGCGACCTTCTCGACGACACGGCGATCCTGGAGGCTGGAGATGGTGTAGACGACCTGCTAGATGGCGAGGACGATGAGcgggaggaggacgacgaagATGGCATGGAAAAGGGGTCAAAGGGACCGGAACCGGACGACGATGCCCTCTTTGATTTCGAGCTGGAGCCGATTGTGAGCATTGGAGAGCCGTCGCCGGCATCGGTTCTGGCACCCGCCGGTCCGATGGGCGCCCAAGTGCGCCCAGCTCTGCAGCGACATTCACTGCCGGCCCTGAGTCGCCCGCGGTCCGATACGCGTCCGATTGGGTTTCCCGTGCGTCCCACCACCTCCCAGATAAATGCCACCGATGAGAACGGCGTGCCCATCAACTATGAGCTGGGCGTGGTGTACATCTGCCCAGCCTGTGGCGGAGAGTTCCGGCAGCAGGACCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACCCTTCGGGGCCTCAACTTTGCGCCGCTGGACAAGCTATATCAGCGCTGCAAGGAGTGTAACAAGCGAATCGCTATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACACACCTGCCGTTCCGGTGCACCAAGTGCTACATTTGCAAGCGGGAATATAAATACAGACAAGATCTAATGGTGCACCTTCGCATGGTGCACTGCGACGAAGTGGTGGCCATGATGCGGGAAGGTTACAATGCTGCCGGACGCAAAACCCGTGTCCGAGAGTCTCGTACTGAGCAAATGCAGCGGGAGAAGAGTTTTCTAGAGGATGAGGACCTAGATAACATCGAGGTACGAAACGAGCTGCTCGAGCCGGACGCTGATGAGTCTGGCGGCATGGAGCATCATTCGTCGCTGCTGGTAGAGGAGACGCCCCATAAGAAGCGACCCGGTGGCATCGCCGGAGAAGCCGCTGAGCTGTGCGAGGACTACATCCACTACATGTGCCCCGACTGCGGCACCGAGTGCGACACCCACGCCCAGTGGAGCCAGCACATTGAGTTTGTCCACGACTATGTCAGCCGGCGTGGCCTCAACTTTCGGAGTGTCGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTGACACCCAACACCATCAAGTCGCTGCGCTCCCACAAATTCAGTCACTTGTCGCACCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGAACATCCGGAACTAGTTAGGCATCtgttaaaaatgcataatCTGGAGACTCTGATGTCGCAGGACCCTGGCCAGGAAGAGGAGGATGCCTCATTAACCATAGATGGGAGCAATGAATGCGAAGACAATGGCAATGGCGAGGGAAACGGCGCCGCCTTGGACGAGGATTCGCCGTACTTTGAAGACGCCCCCCGACGCGGCGGTCGTATTAGCAGCGATGACATTTTCGAACCGCACATTGACTACCTCTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTCATGGCGCACAGCATGAACGATCTGTCGAAGCTGAACTTCGAGATGATCAACGAACGGCAGCTAAAGTGCACCGAATGCGACAAGATTATCACGAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATCACCCATCTGCCATTTAAGGCGTATGCCAGGTGCCGCAAGTGCCACAAGTCTTACACTGATCGAAAAGGTCTCGTCAAGCATCTGGCCACCTATCACCGCATCGGCTGTGATTCCAGGAAGTCTGGTGGGGGTGCACCGCCACCTTTACCCATGCTAACAACTCCCAAGCAACCTCGCAAGCAGATCGTCACAGTGGCCAATGAGACCTACGAGATTATCTACTTGGACGATATGGAGAGCAGCTTGGATGAGGAGAATGACTTTGGGGAGCAAATGCTCGCTGACGATGACGATTATCCGGTTATCCAGCCGCCGCAACAACGCCAGGTGCCGCCTCCGCCACGACCCCCGCAGAACACTCAGCAACGCTACAAGTGTGTGCACTGCAGCACTCTCTTCCCCACCCAGGTGGCGGTGCGGATGCACATCAGCGAGAAGCACTGCCGGAAGCCGCATCAGACAGGCAGAAGGCATCGCCATTTGATTGCAAACTCCGGTGGAGCAGACACTGGCCGTACCACCGTGGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAACGAGGAGCACAACTTTGACAAGCGAAACTACCTGAACATGCGGCAGTTGGACAAGTATCGCTACCAGTGCACACAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTGCAGGACCATCACTTCCGCCACCTGCCATACCGCCTGTATCTCAAGTGCTTAGTCTGCGGCACCTGCTACAACCACAAGCCGAACATAGCGGCACATCTCAGGGCGCGCCACAACATCTACGACAAAGAGACGCCCGTGATGATCACCAAACCGATGAAAACCTACAGTCGGTTCAAGGATGGGGATAAAGAGAAGATCGCGCTACCCATTCCCGCACCGGCAGCAGGATCTCCACCCGGctgctccgcctcctcctcctcctcctcagctgttgttgctgctatgCCCGTGGTCAGTCGAACTCTTAAGCCCCAACCCGGTGACCTGCCCACTCGACCCGCTGGCCTGAACACCCTGGAGGACAGCATCTCGTACCACAATGCCGTAGATATGGACTTCATCACGTACTTTTGCCCGAAGTGCAATCAGAACTTCGACTCGCATGCCTTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGTCTCAATTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTGACGGTGACCCACACCAAGGGCGCCATAGGTCAGCTGCAGTCGCACAAGTTCCGGCATCTTCCCCATCGCTCCTTCAAGTGTCTGACCTGCGACGCCTCGTTTGTGCGCAAGCAAATGTTTTTCAAGCACCTGAATCGGGACACCAACCGGTGTGACAATCGTCCGCAACGCGAGCTGGACGATGAAGAGCCCAGCCAGGACGCTCAGCTGACCACCATTTACCACTTGGCGTGTCCACAGTGCGGCGATGACTTCAACACTGCCAGTCGGAAGCAGTGGCGCGATCACATTAACGTCTTTCACGGCCTCACCGCTCTGGACGTGCTGCACATGAACAAGGTGGATGGCGCGCAGGATCTCTATCGTTGCCAGGACTGCAACGAGGAGTTGCAGACGAACCGGCAGTGGGTGCTGCAATACCATCGCTTTCAGCATCTGCCACAGCCGGCCTACATCCGCTGCCAGCTGTGCGAGCAGAACAGTGAGCAAGATGCGGCAGTGGCATCCGGGATGCATAGTCTACgcgagctgcagcagcatctACGCAAGCATCATCCCACAACGGTGGGCGAGAACGAGATGCAGATGCTCCGCGAACAGATTGcccaggaggagaaggagcaggatgAGACAGTGGGCCtggctgcagatgaggaggaCAACCAGACGGGCCAGGACTCAGGACGCTACATGCCGCTTCCGCCGCATTTATTGGACGACGGAGACGATGTGGAATTTGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSEFEEPEGGGEVEMQEGGEDGAQYGNGNGDLLDDTAILEAGDGVDDLLDGEDDEREEDDEDGMEKGSKGPEPDDDALFDFELEPIVSIGEPSPASVLAPAGPMGAQVRPALQRHSLPALSRPRSDTRPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMQREKSFLEDEDLDNIEVRNELLEPDADESGGMEHHSSLLVEETPHKKRPGGIAGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRSHKFSHLSHPEWLRCKLCYKGYTEHPELVRHLLKMHNLETLMSQDPGQEEEDASLTIDGSNECEDNGNGEGNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDSRKSGGGAPPPLPMLTTPKQPRKQIVTVANETYEIIYLDDMESSLDEENDFGEQMLADDDDYPVIQPPQQRQVPPPPRPPQNTQQRYKCVHCSTLFPTQVAVRMHISEKHCRKPHQTGRRHRHLIANSGGADTGRTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIYDKETPVMITKPMKTYSRFKDGDKEKIALPIPAPAAGSPPGCSASSSSSSAVVAAMPVVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSQDAQLTTIYHLACPQCGDDFNTASRKQWRDHINVFHGLTALDVLHMNKVDGAQDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQNSEQDAAVASGMHSLRELQQHLRKHHPTTVGENEMQMLREQIAQEEKEQDETVGLAADEEDNQTGQDSGRYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492530;
90% Identity: iTF_00541377;
80% Identity: -