Basic Information

Insect: Drosophila hamatofila
Gene Symbol: RREB1
Assembly: GCA_035045345.1
Location: JAWNPA010000041.1:6033099-6039470[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0059 0.43 11.3 0.6 1 21 247 267 247 269 0.96

2 13 0.00034 0.025 15.2 0.2 1 23 279 301 279 301 0.98

3 13 8.1e-05 0.006 17.2 7.3 1 23 307 329 307 329 0.98

4 13 0.045 3.3 8.5 0.8 2 20 527 545 527 547 0.93

5 13 0.0089 0.65 10.7 0.1 1 23 702 724 702 724 0.97

6 13 1.2e-05 0.00091 19.7 0.7 1 23 734 756 734 756 0.99

7 13 0.00083 0.061 14.0 2.0 1 23 762 785 762 785 0.97

8 13 0.003 0.22 12.2 2.0 1 23 1038 1061 1038 1061 0.95

9 13 8.6e-05 0.0064 17.1 0.3 2 23 1412 1433 1411 1433 0.97

10 13 0.15 11 6.9 6.3 1 23 1439 1462 1439 1462 0.97

11 13 2.4 1.8e+02 3.1 3.8 1 23 1579 1602 1579 1602 0.87

12 13 0.0084 0.62 10.8 0.5 3 23 1667 1687 1665 1687 0.96

13 13 0.0013 0.099 13.3 4.8 1 23 1693 1715 1693 1715 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0059	0.43	11.3	0.6	1	21	247	267	247	269	0.96
2	13	0.00034	0.025	15.2	0.2	1	23	279	301	279	301	0.98
3	13	8.1e-05	0.006	17.2	7.3	1	23	307	329	307	329	0.98
4	13	0.045	3.3	8.5	0.8	2	20	527	545	527	547	0.93
5	13	0.0089	0.65	10.7	0.1	1	23	702	724	702	724	0.97
6	13	1.2e-05	0.00091	19.7	0.7	1	23	734	756	734	756	0.99
7	13	0.00083	0.061	14.0	2.0	1	23	762	785	762	785	0.97
8	13	0.003	0.22	12.2	2.0	1	23	1038	1061	1038	1061	0.95
9	13	8.6e-05	0.0064	17.1	0.3	2	23	1412	1433	1411	1433	0.97
10	13	0.15	11	6.9	6.3	1	23	1439	1462	1439	1462	0.97
11	13	2.4	1.8e+02	3.1	3.8	1	23	1579	1602	1579	1602	0.87
12	13	0.0084	0.62	10.8	0.5	3	23	1667	1687	1665	1687	0.96
13	13	0.0013	0.099	13.3	4.8	1	23	1693	1715	1693	1715	0.99

Sequence Information

Coding Sequence: atGCTGgccacacagcagcaacagcagcaacagccacaacagcaacatacagcagcaacagcagcggcagcattgACGCTTGAGGATGCGGTCATGGAGCGACAGCGTCGTGACTCCAGCACCTCGGAGTCATCGCTGGAGCATCTGGATCTGGGTCGCACGCCAAAGAAgctgagcagcaacagcggtgCGCTGCAGCCGACGTCGACGCCGCACGTTGAGGCGACTTCGCGGAAGCGCAAgatgcgacagcagcagcagcaacagcaatcctTGTACTCTGACGAGGAGgacgaacagcagcagcagcagcagcaacagcagcaacagcagcaacagttgctggaGCAGTCGGTGCATCGCATTCGCCACAAGCAGCGCCGCAGCGGCAATGCAGTCGCAGCCGCTGCCAGCGCCAGCATCGTCGTCGACTACAGCGTCGGCAGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGCCTGAAtcgcagcagcatcagcgccCAGAACGGCGACCTCTCCGAGTCGGGCTTCGTCGATGGCAGCTCACACAGCGGCTATTTGCTTAGCGCCAGCGCCGCAGCGCAGTCGACGACggcggcgcagcagcagcagcagcagcagcaacaacaacagcagcagcagccgggcTCGGGCAGCAGCTCGGGCGGCTCTTCGCCGCAAGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCAGCGCCGGCGACGAGCACATGAAATATGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACTGAGAACTTCACTTGCCGCATTTGCTCCAAGGTACTCTCGTCAGCGTCCTCGCTGGACAGACACGTCCTGGTGCACACCGGGGAGCGACCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACAAATGGCAACATGCATCGGCACATGCGAACACAcaagcaacatcagcagcagcaacagcagcagcagtcgcagcagcagcaacagtcacagcaacagtcacagtcacagcaacagcagcagcagcagcagcagcaacaacagttacaGCGACATCAGCAACATTCGGCATCGAATTCGGTTTCTCAGCGTGCCGAGAGCTATGAAAGCGATGCCAGTTGCTCCACGGATatatccagcagcagcagcagtgtagccagcaacaacaacaacaacaacaacagcagccaagcgaacaagaacaacaatgaggaacagcaactgaagctgaagacaaacatcaacaacaacaacatcattgTCAGCGACGAACGAGCGCTGGATACAGACGGCGATGGGGATGGAGACGAGGGCGGGGATGGAGAGAGCGTGGATGTAACACAGATGATAACGAGCACACCCGATGTGGCCACACTGCTGGCGACGTCGTCGGGCAACAGCAGCCCGAGGACAATGGAGCCGGAGTTGGAGACGCTGCCCAGCTGCCCCGTCTGCAATGGCGGCGAGTTCGAGACACTGGCCGCGCTGTACGCCCACTTGGAGGCGGAGCACGCCGATATACCCGCCAAGTGTCGCGAATGCGAGGTGATCTTTGCCACGCAGCGTCAACTGCAGGCGCACAGCTGTCGGGGATTGCagttgccgccgctgctgggCGCCAGCTCGTCGCCGCTGCACAAGCAGGAGCCGGCcgaggatgaggaggatgacgaggagcagcagcgccagcttcagcagcagcagcgcgagGATGAGGCCGAGGCTGAGGAGGACGAGGAGGAGTTGCGTCTGCaggcgagcagcgagcaggaCGAGTTCTTTAAGCAGCTGTACCTCAAGGGCAAGTCGGGCGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGATCTGGCCGACATACAGAGCATCCTGCACAtgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGATGGGCGCGACGGCGAGGAGGAGGCCCAGGATGCCTTCACCAGCGAATTCCGACGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCACCTGGCCGCCGTCGGCGCCGCCGGCCCCTTTCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCTCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCATACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGCCATCTGCGCAATCGCCATGGCAAGACGAGCCGCGACGAGGTGAAGCGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGACATCAAGCCCAAGCTGGATCCCGATATGTCGGAGCTCAGCTTTCGCTCGCTCAGTCCGTCGCCGTCGGCGACCAATGTGGAGGCGAGCTCCCAGCTGAAGCACATGCTGCTGGCAGAGCAGCCCagtaagcagcaacaacaacaacagcagcaacagcagcagcagccgccacagCCGGCGCAGCCTCCGTTGAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTGGCACCTGCCATGGATCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAACGCGAACATGACTTActcttgcagcagcagcagcaactgcaacagcagcagcaacaacagcagcagcagcagcagcaacagttgctctTCAATCCGGGTGATGCTGCGACGCAGTATATGCAGCTACTCCGTAATCTGATGCTGCAGCAGTCGTCCGGCTTTCCGTTCTTCGGACTGATGgcgccgcctcctgctgctgcgctggAGAAGTCAGCGCCAGCGATTGCAGTGCCAGCGacaccagcaacagttgctgcagtGCCGTCGCCTTTGGGCCTGCCCCTGGGCGGAATGGGCGTGCCGGTGCCAGCGGCCGGGCCCGTCAAGATGGTCATCAAGAACGGTGTGCTGATGCCCAAGCAAAAGCAGCGCCGCTACCGCACCGAACGGCCCTTCGCCTGCGAGCACTGCTCGGCCAGATTCACGCTGCGCTCCAACATGGAGCGCCATgtcaagcagcagcatccgcagTTCTATGCGCAGCGACAGCGCAGCGGCCACCACGTGATGCGTGGCCGGGCGGCCAACTCGGGTgcggcacaagcagcagcagcagcagcagcagcagcggcggcagcagcagcagccgcagcagccatGACAAATctgcatcagcaacatcagcagcagcagcagcaacagcaacagcagcagcagcagcagcagcatccgccCATATCGGAGCAGGTGAAATACGCGATCTTGGCGCAGCAGTTGGCGCGCAAGGAGACGGACTTGCTGCAGCAGGCGCTGGCGCATGGCTCTAGCAGCGTTGCCGTCAATCCGTTGCTGCACTttggctacaacaacaacagcagcagtggatGCAGCGGCgccaacggcaacggcagcagcaacagcaacagcaatgccaATGACAGCAatcaggcgcagcagcagcaacagttgcccgTGGATGACGATGAGCCGCCCAAGCTGATCATAGACgaggacgacgatgatgatttCGATGACAtagacgaggaggaggaggaggaggaggacgaggaGCTGGACCAAGacgaacaacagcagcaacagcaggaggagcagcagcaacacgaacagcagcagcagcagcagctgcagcagcaagtgcagccaattgaaattgatgcCAAAGAGGAGCCAGAGCCGCTCGTTGAGTCGGCCGAggcgaaactgaaactgaagccCAGCGGCGAGCCGACAACAATGAAGACAATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGGACCTGGTGCCGGTGGCGAAGCTGGTGGACAATGCCACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGATGTGGCCAACCACATGGAGCAGAGTGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagcCGAAGAAGAAGTCCGCCTACAGCCTGGCACCGAATCGCGTCAGCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGTGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGATGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGGCGCCGCAAGGCGGCCGAGCAGGAGCgccagctggagctggagcgtgAACGGGAGCGCGAACGTGAACTGGAGCGGGAGCGTGAGCTGGAGCGCGagcgcaagcagcagcagctcatccAGCAGCTGACGGCGGCGGCTCAGCTCAGCCAGCAAATGGTGGCCGCAGCTCAGGCTGCTGCCGTCGCCGctgccaccaccagcagcagcagcgctgcaGCCGAGACCAATGGCAGCGAGCTGCCCTACAAGTGTCACCTGTGCGAGTATTCGTTCGGCGAGCGGATGCAGTGCCTCGATCACATCAAGCTGCAGCACGCCCAGGAGTTtgctctgctgctggccaaaggCGCCATCGAGACGGAGCAGGaggtggcaacagcagcggcagcaacggccacagccacagccacagctgcagcagcttctgCAGCGGCCGTCTCTGAGGATGAGTCGAGCACAGGACGCAGCTCTGGCAAATATCCGGACTACAGCAATCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACAGAGGATCTGCGCCGTCACATGCGCACCCACTCCGGCGAGCGTCCGTTCCAGTGCGAGATCTGCTTGCGCAAGTTCACCCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACACAGTCACAATGGCGAGCCGGGCGCCTCCGATTGCTCCGATGATGAGCAAATGGCAACGCCGCCCACAACACCAACGCCCACGGCCATgaccatgcccatgcccatgccaatgcccagcagcaacaacaacaacaacaacaacaacaacacttgccacaacaacaacaacaacaacaagagcgtGCGTCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCAAACGAATGGCGCGTCAGTCGCCTGGGCGAGCACAAGGAAAACATTGCCGAATCCTCTGCGCCCGCAACAGCGGccgctgtgggcgtggccagcggTGATTTCCTGGGCAATCTGCTGGGCATCACCGACCAAGGCATACTGAACAAGCTGCTCAGCTCACCCGACGAGGCGGCCAAATTGCTGGGCGTCGAGAAGTGA
Protein Sequence: MLATQQQQQQQPQQQHTAATAAAALTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSNSGALQPTSTPHVEATSRKRKMRQQQQQQQSLYSDEEDEQQQQQQQQQQQQQQLLEQSVHRIRHKQRRSGNAVAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAQNGDLSESGFVDGSSHSGYLLSASAAAQSTTAAQQQQQQQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGISAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQQQQQQSQQQQQSQQQSQSQQQQQQQQQQQQLQRHQQHSASNSVSQRAESYESDASCSTDISSSSSSVASNNNNNNNSSQANKNNNEEQQLKLKTNINNNNIIVSDERALDTDGDGDGDEGGDGESVDVTQMITSTPDVATLLATSSGNSSPRTMEPELETLPSCPVCNGGEFETLAALYAHLEAEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPAEDEEDDEEQQRQLQQQQREDEAEAEEDEEELRLQASSEQDEFFKQLYLKGKSGGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKLDPDMSELSFRSLSPSPSATNVEASSQLKHMLLAEQPSKQQQQQQQQQQQQPPQPAQPPLKIQVKSLDQLVEKPLAPAMDLSMDVLDLSKKPQREHDLLLQQQQQLQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSSGFPFFGLMAPPPAAALEKSAPAIAVPATPATVAAVPSPLGLPLGGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAAMTNLHQQHQQQQQQQQQQQQQQQHPPISEQVKYAILAQQLARKETDLLQQALAHGSSSVAVNPLLHFGYNNNSSSGCSGANGNGSSNSNSNANDSNQAQQQQQLPVDDDEPPKLIIDEDDDDDFDDIDEEEEEEEDEELDQDEQQQQQQEEQQQHEQQQQQQLQQQVQPIEIDAKEEPEPLVESAEAKLKLKPSGEPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAAVAAATTSSSSAAAETNGSELPYKCHLCEYSFGERMQCLDHIKLQHAQEFALLLAKGAIETEQEVATAAAATATATATAAAASAAAVSEDESSTGRSSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGHSHNGEPGASDCSDDEQMATPPTTPTPTAMTMPMPMPMPSSNNNNNNNNNTCHNNNNNNKSVRLPKLHELLDKANEWRVSRLGEHKENIAESSAPATAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512904;
90% Identity: iTF_00540546; iTF_00551780; iTF_00473253; iTF_00554566; iTF_00479659; iTF_00493840;
80% Identity: -