Basic Information

Insect: Drosophila navojoa
Gene Symbol: RREB1
Assembly: GCA_001654015.2
Location: NW:8899-18491[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0046 0.27 11.3 0.6 1 21 249 269 249 271 0.96

2 13 0.00027 0.015 15.2 0.2 1 23 281 303 281 303 0.98

3 13 2.6e-05 0.0015 18.4 5.1 1 23 309 331 309 331 0.98

4 13 0.035 2 8.5 0.8 2 20 535 553 535 555 0.93

5 13 0.0066 0.38 10.8 0.1 1 23 722 744 722 744 0.97

6 13 9.8e-06 0.00056 19.7 0.7 1 23 754 776 754 776 0.99

7 13 0.00066 0.038 14.0 2.0 1 23 782 805 782 805 0.97

8 13 0.0023 0.13 12.2 2.0 1 23 1058 1081 1058 1081 0.95

9 13 6.8e-05 0.0039 17.1 0.3 2 23 1424 1445 1423 1445 0.97

10 13 0.11 6.6 6.9 6.3 1 23 1451 1474 1451 1474 0.97

11 13 2.5 1.4e+02 2.7 4.2 1 23 1596 1619 1596 1619 0.88

12 13 0.0067 0.38 10.8 0.5 3 23 1678 1698 1676 1698 0.96

13 13 0.0064 0.37 10.8 5.0 1 23 1704 1726 1704 1726 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0046	0.27	11.3	0.6	1	21	249	269	249	271	0.96
2	13	0.00027	0.015	15.2	0.2	1	23	281	303	281	303	0.98
3	13	2.6e-05	0.0015	18.4	5.1	1	23	309	331	309	331	0.98
4	13	0.035	2	8.5	0.8	2	20	535	553	535	555	0.93
5	13	0.0066	0.38	10.8	0.1	1	23	722	744	722	744	0.97
6	13	9.8e-06	0.00056	19.7	0.7	1	23	754	776	754	776	0.99
7	13	0.00066	0.038	14.0	2.0	1	23	782	805	782	805	0.97
8	13	0.0023	0.13	12.2	2.0	1	23	1058	1081	1058	1081	0.95
9	13	6.8e-05	0.0039	17.1	0.3	2	23	1424	1445	1423	1445	0.97
10	13	0.11	6.6	6.9	6.3	1	23	1451	1474	1451	1474	0.97
11	13	2.5	1.4e+02	2.7	4.2	1	23	1596	1619	1596	1619	0.88
12	13	0.0067	0.38	10.8	0.5	3	23	1678	1698	1676	1698	0.96
13	13	0.0064	0.37	10.8	5.0	1	23	1704	1726	1704	1726	0.99

Sequence Information

Coding Sequence: atgctggccacacagcagcaacagcagcaacagccacaacagcaacatgcagcagcaacagcagcggcagcagcattgACGCTTGAAGATGCGGTTATGGAGCGACAGCGTCGCGACTCCAGCACCTCGGAGTCATCGCTGGAGCACCTGGATCTGGGTCGCACGCCAAAGAagctgagcagcaacagcggcgcgCTGCAGCCGACGTCCACGCCGAACGTTGAAGCGTCCTCGCGGAAGCGCAAgatgcgacagcagcagcagcagcagcagcagccattctTGTATTCTGACGAGGAggacgaacagcagcagcaacagcaacagcagcaacagcagcagcagcaacagttgctggagCAGTCGGTGCATCGCATTCGCCACAAGCAGCGCCGCAGCGGCAATGCAGCCGCGGCCGCGgccgctgccagcgccagcaTCGTCGTCGACTACAGCGTCGGCAGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcatcagcgccCACAACGGCGACCTATCCGAGTCGGGCTTCGTCGATGGCAGCGCGCACAGCGGCTATTTGCTTAGCGCCAGCGCCGCAGCGCAGTCGGCGACGggcgcgcagcagcagcagcaacagcagcagcagcagccgggcTCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAGGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCAGCGCCGGCGACGAGCACATGAAATATGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTACTCTCGTCAGCCTCCTCGCTGGACAGACACGTCCTGGTGCACACCGGGGAGCGGCCCTTCAACTGTCGCTACTGCCAGTTGACCTTCACGACAAATGGCAACATGCATCGGCACATGCGAACACAcaagcaacatcagcaacatcagcagcagcagcagcagcaacagcagcagcaacaacagcaacagcagccacagcagcagcaacagcaacagcagcagcaggcacagcagcaacagttgcagcgaCATCAGCAACATGCGGCAGCCAATCAGCGTGCCGAGAGCTATGAAAGCGATGCCAGTTGCTCCACGGATatatccagcagcagcagcagtgcagccagcaacaacaataacaacaacaacaacagtagccaagcgaacaacaacaacaacattgaggAACAGCGACTGAAGCTAAAgacaaacatcaacaacaacaacatcattgTGAGCGACGAGCGAGCGCTGGAGGCAGACGCCGATGGCGATGGGTCTGGGCATGGAGAGGAGGCCGGGGCCGATGGGGAGAGCGTGGATGTGACACAGATGATAACGAGCACGCCCGATGTGGCCACATTGCTGGCAACGTCGTcgggcaacagcagccccCAGACGCTGGAGCACGAGCTGGAGACGCTGCACAGCTGCCCCGCCTGCGATGCCGGCGAGTTTGAGACGCGAGGCGCACTGTACGCCCACTTGGAGGCGGAGCACGCCGATATACCCGCCAAGTGTCGCGAGTGCGAGGTGATCTTTGCCACGCAGCGTCAGCTGCAGGCGCACAGCTGTCGGGGATTgcagttgccgccgctgctgggcGCCAGCTCGTCGCCGCTGCACAAGCAGGAGCCGGctgagctggaggaggagaaCGAGTATGatgaagagcagcagcagcagcagcaccagcagcaggtgcGCCTGCAccaccagcatcagcagcgcGAGGGTGAGCCAACggccgaggaggaggaggaggagatgCGACTGCAGGCGAACAGCGAGCGGGACGAGTTCTTTCAGCAGCTGTACCTCAAGGGCAAGTCGAGCGGCTCCTCGCTGCCGTCACCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGATCTGGCCGACATACAGAGCATCCTGCACAtgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTGAACACGCCCTGCTCCAGCCAGTACAGCGTGGATGGGCGCGACGGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAATTCCGGCGGATGAAGCTGCGCGGCGAATTCCCCTGCAAACTCTGCACCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTGGCGGCCGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCTCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGCCACCTGCGCAATCGGCACGGCAAGACCAGCCGCGACGAGGTGAAGCGCGCGATCGTCTATCACCCGGCCGAGGATGCCAGCTGCGAGGACATCAAGCCCAAGATGGATCCCGATCTGTCGGAGCTCAGCTTTCGCTCGCTCAGTCCGTCGCCGTCGACGACCAATGTGGAGGCCAGCTCCCAGCTGAAGCACATGTTGCTGGCAGAGCAGCCcaccaagcagcagcagcaacagcagcagcaacaacagcagcagcagcagcagcaaccgtcGCAGCCTCCGTTAAAGATTCAAGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTGGCACCTGCCATGGATCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAACGCGAACATGACTTGCtcgtgcaacagcagcagcagcagcagcaacaacagcagcaacagcagcagcagcagcaacagttgctcttCAATCCGGGCGATGCGGCGACGCAGTatatgcagctgctgcgcaatCTGATGCTGCAGCAGTCGCCCGGCTTTCCGTTCTTCGGGCTGATGGCGCcaccgccagctgctgcgctgGAGAAGTCAGCGCCAGCGATGGCAGTGCCAGCGGCgccggcaacagttgctgccgtgCCGCAGCCCTTGGGGCTGCCCCTGCCCGGCATGGGTGTGCCGGTGCCAGCGGCCGGGCCTGTCAAGATGGTCATCAAGAACGGCGTGCTGATGcccaagcagaagcagcgccgCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCGGCCAGGTTCACGCTGCGCTCGAACATGGAGCGCCATgtcaagcagcagcatccgcagTTCTATGCGCAGCGACAGCGCAGCGGGCACCACGTGATGCGCGGTCGGGCGGCCAACTCGGGCGCggcgcaggcagcagcagccgcagcagcagcggcggcagcggcagcagcagccgccgcagccatGACAAatctgcaccagcagcagcagcagcagcagcagcaacagcagcagcaacatccgcCCATATCGGAGCAGGTGAAATACGCGATCCtggcgcagcagctggcgcgCAAGGATACGGACTtgctgcagcaggcgctggCCCATGGCTCCAGCAGCGTCGCCGTCAATCCCTTGCTGCACTttggctacaacaacaacagcagcagcagcagcaacggcaacggcggcagcagcagcagcaatgccaacggcagcaatcagacgcagcagcagcaacagttgcccgTGGACGATGATGAGCCGCCCAAGCTGATCATAGACgaggacgatgatgatgatttcgAGGACatcgacgaggaggaggaggaggaggaagacgAAGAGCTAGACCAagacgaacagcagcagcagccgctgcaggaggagcagcaacacgagcagcagcagcagcagcgtgtgGAGCAAGTGCAGCCAATCGAAATTGATGCCAAAGAGGAGCCAGAGCCGCACGCCGAGTCGGCCGCGTCGGCCGCGTCGACCGCGTCGAAGCCCAGTGGCGAGCCGAGCACAATGAAGACAATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTAGCGAAGCTGGTGGACAATGCCACCAGCAATCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagccGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATTCTCACCCACACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACCAAGAGCAACTGCGACCGGCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCGGTGCCCAAGTCCGTCGAGGAGATcgagctggaggagcagcgCCGTCGCAAGGCCGCCGAGCAGGAGcgccagctggagctggagcgcgAGCGGGAGCGCGAACGCGAACTGGAGCGGGAGCGTGAGCTGGAGCGCGagcgcaagcagcagcagctcatccaGCAGCTGACAGCGGCGGCCCAGCTCAGCCAGCAGATGGTGGCCGCGGCTCAGGCCGCTCAggtcgctgccgccgccgcagccaccagcggcgccagcagcggcgctgccgccgccgagGGCAATGGCAGCGAGCTGCCGTACAAGTGCCACCTGTGCGAGTATTCGTTCGGCGAGCGGATGCAGTGCCTGGACCACatcaagcagcagcacgccCAGGAGTTTGCTCTGCTCCTGGCCAAGGGCGCCATCGAGACGGAGCAGGaggtggcagcagcggctgtggctacagcagcgactgctgcctctgccgccgtCTCGGAGGACGAGTCCAGCACCGGCCGTAGCGCTGGCAAATATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACGGAGGATCTGCGCCGTCACATGCGCACCCACTCCGGCGAGCGTCCGTTCCAGTGCGACATCTGCATGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACATAGCCACAATGGCGAGACGGGCGCCTCCGATTGCTCCGACGATGAGCAAATGGCCACGCCGCCCACAACACCAACGCCCACGGTCATGCCCATGCCAatgcccagcaacaacaacaataacaacacttgccacaacaacaacaacaccaacaataacaacaacaacaacaacaacaacaagggcgTACGTCTACCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAATGGCGCGTCAGTCGCCTGGGCGAGCACAAGGAGAACATTGCCGAATCCTCAGCggccacaacagcagccgctgtgggcgtggccagcggTGATTTCCTCGGCAATCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCCGACGAGGCGGCCAAACTGCTGGGCGTCGAGAAGTGA
Protein Sequence: MLATQQQQQQQPQQQHAAATAAAAALTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSNSGALQPTSTPNVEASSRKRKMRQQQQQQQQPFLYSDEEDEQQQQQQQQQQQQQQQLLEQSVHRIRHKQRRSGNAAAAAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDGSAHSGYLLSASAAAQSATGAQQQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGISAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCQLTFTTNGNMHRHMRTHKQHQQHQQQQQQQQQQQQQQQQPQQQQQQQQQQAQQQQLQRHQQHAAANQRAESYESDASCSTDISSSSSSAASNNNNNNNNSSQANNNNNIEEQRLKLKTNINNNNIIVSDERALEADADGDGSGHGEEAGADGESVDVTQMITSTPDVATLLATSSGNSSPQTLEHELETLHSCPACDAGEFETRGALYAHLEAEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPAELEEENEYDEEQQQQQHQQQVRLHHQHQQREGEPTAEEEEEEMRLQANSERDEFFQQLYLKGKSSGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSVDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKMDPDLSELSFRSLSPSPSTTNVEASSQLKHMLLAEQPTKQQQQQQQQQQQQQQQQPSQPPLKIQVKSLDQLVEKPLAPAMDLSMDVLDLSKKPQREHDLLVQQQQQQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSPGFPFFGLMAPPPAAALEKSAPAMAVPAAPATVAAVPQPLGLPLPGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAAMTNLHQQQQQQQQQQQQQHPPISEQVKYAILAQQLARKDTDLLQQALAHGSSSVAVNPLLHFGYNNNSSSSSNGNGGSSSSNANGSNQTQQQQQLPVDDDEPPKLIIDEDDDDDFEDIDEEEEEEEDEELDQDEQQQQPLQEEQQHEQQQQQRVEQVQPIEIDAKEEPEPHAESAASAASTASKPSGEPSTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAQVAAAAAATSGASSGAAAAEGNGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQEVAAAAVATAATAASAAVSEDESSTGRSAGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICMRKFTLKHSMLRHMKKHSGHSHNGETGASDCSDDEQMATPPTTPTPTVMPMPMPSNNNNNNTCHNNNNTNNNNNNNNNNKGVRLPKLHELLDKANEWRVSRLGEHKENIAESSAATTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512904;
90% Identity: iTF_00516459;
80% Identity: -