Dmay016063.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mayaguana
Gene Symbol
RREB1
Assembly
GCA_037075325.1
Location
JBAMCG010000127.1:5723508-5730082[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0057 0.39 11.3 0.6 1 21 247 267 247 269 0.96
2 13 0.00033 0.022 15.2 0.2 1 23 279 301 279 301 0.98
3 13 7.9e-05 0.0054 17.1 7.3 1 23 307 329 307 329 0.98
4 13 0.044 3 8.5 0.8 2 20 543 561 543 563 0.93
5 13 0.0082 0.56 10.8 0.1 1 23 725 747 725 747 0.97
6 13 1.2e-05 0.00083 19.7 0.7 1 23 757 779 757 779 0.99
7 13 0.00081 0.056 14.0 2.0 1 23 785 808 785 808 0.97
8 13 0.0029 0.2 12.2 2.0 1 23 1056 1079 1056 1079 0.95
9 13 8.5e-05 0.0058 17.0 0.3 2 23 1432 1453 1431 1453 0.97
10 13 0.14 9.7 6.9 6.3 1 23 1459 1482 1459 1482 0.97
11 13 3.1 2.1e+02 2.7 4.2 1 23 1600 1623 1600 1623 0.88
12 13 0.0083 0.57 10.8 0.5 3 23 1686 1706 1684 1706 0.96
13 13 0.0014 0.094 13.2 4.8 1 23 1712 1734 1712 1734 0.99

Sequence Information

Coding Sequence
atgCTGgccacgcagcagcaacagcagcagcagccacaacagcaacatgcagcagcaacagcagccacaccaGCATTGACGCTCGAGGAAGCGGTTATGGAGCGACAGCGTCGGGACTCCAGCACCTCAGAGTCATCGCTGGAGCACCTGGATCTGGGTCGCACGCCAAAGaagctgagcagcaacagcggtgCGCTGCagccgacgtcgacgccgaACGTTGAGGCGTCTTCGCGGAAGCGCAAgatgcgacagcagcagcagcaacagcagcagcaattcttGTACTCTGACGAGGAggacgaacagcagcagcaacagcaacagcagcagcaacaacagcagcaacagttgctggaGCAGTCGGTGCATCGCATTCGCCACAAGCAGCGCCGTAGCGGCAATGCAGCTGgcaatgctgccgctgccagcgccagcaTCGTCGTCGACTACAGCGTCGGCAGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGTCTGAatcgcagcagcatcagcgccCACAACGGCGACCTCTCCGAGTCGGGCTTCGTCGATGGCAGCGCGCACAGCGGTTATTTGCTTAGCGCCAGCGCCGCAGCGCAGTCGGCAACggcggcgcagcagcagcagcaacagcagcagccgggctCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAAGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCAGCGCCGGCGACGAGCACATGAAATATGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTACGCCAACGGCGACACAGAGAACTTCACCTGCCGCATCTGCTCCAAGGTACTCTCGTCAGCCTCCTCGCTGGACAGACACGTCCTGGTGCACACCGGGGAGCGGCCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACAAATGGCAACATGCATCGGCACATGCGAACACAcaagcaacatcagcaacatcaacaacatcatcagcagcagcagcagcagcagcagcagcaacagcagcagcagccgcagcaacagcaatcgctgacacagcagcaacagtcacagccacaacagcagcagttgcagcgacagcagcaacattcgGCATCCAATCAACGTGCCGAGAGCTATGAAAGCGATGCCAGTTGCTCTACAGATatatccagcagcagcagcagtgcagccagcaacaacaacaacaacaacagccaagcgaacaacaacaacactgagGAGCAGCGACTGAAGCTGAAGActaacatcaacaacaacaacatcattgTCAGCGACGAGCGCACGCTGGATACAGACGCCGATGGCGATGGAGATGGCGATTGCGATGGGGacgggaatgggaatggggatAGGCATGGAGAGGAGGCCGGCGATGGGGAGAGCGTAGATGTGGCACAGATGATAACGAGCACACCCGACGTGGCTACATTGCTGGCGACGTCGTCGGGCAACAGCAGCCCGAGAACGCTGGAGCCCGAGCAGGAGGCGCGCTGCCCCGTCTGCAATGCCGGCGAGTTCGAGACGCTGGCCGCGCTGTACGCCCACTTGGAGGCGGAGCACGCCGATATACCCGCCAAGTGTCGCGAATGCGAAGTGATCTTTGCcacgcagcggcagctgcaggcgCACAGCTGTCGGGGATTGcagttgccgccgctgctgggCGCCAGCTCGTCGCCCCTGCACAAGCAGGAGCCGCcggaggaagaggaggagttTGACGAAGATCAGCACCAGGCacggctgcagcaacagcagcagctgcagcagcagcgcgaggATCAGACGACGGCTGGGGAGGACGAGGAGGAGATGCGCCTACAGGCGAACAGCGAGCGGGACGAGTTCTTTCAACAGCTTTACCTCAAGGGCAAGTCGGGCGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGACCTGGCCGACATACAGAGCATCCTGCACAtgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTGAATACGCCGTGCTCCAGCCAGTACAGCGTGGATGGGCGCGACTGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAATTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAACTGTGCACCGCCGTCTTTCCCAATCTGCGCGCTCTCAAAGGCCACAATCGCGTCCACCTGGCAGCTGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCCCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGCCACCTGCGCAATCGCCATGGCAAGACGAGCCGCGACGAGGTGAAGCGCGCGATCGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGACATGAAGCCCAAGATGGATCCTGATCTGTCGGAGCTCAGCTTTCGCTCGCTCAGTCCGTCGTCGTCGACGACCAATGTGGAGGCGAGCTCCCAGCTGAAGCACATGCTACTGGCAGAGCAGcccagcaagcagcagcagcagcaacaacagcagcagcaacagcagcagcagccgcaacctCCGCTAAAGATTCAAGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTAGCACCTGCCATGGATCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAACGCGAACACGACTTacttgtgcagcagcagcagcagcagcagcagcaacagcagcaacaacagcagcagcagcagcagttgctcttCAATCAGGGCGATGCAGCGACTCAGTATAtgaagctgatgctgatgctgcagcagTCGTCCGGCTTTCCGTTCTTTGGGCTGATGGCGCCACCGCCAGCTGCTGCGCTGGAGAAGTCAGCGCCGGCGATTGCTGTGCCAGCGACgccggcaacagttgctgccgtgCCGCCGCCCTTGGGCCTGTCCTTGCCCGGCATGGGCGTGCCGGTGCCAGCGGCCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGcccaagcagaagcagcgccGCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCGGCCAGGTTCACGCTGCGCTCCAACATGGAGCGCCACgtcaagcagcagcatccgcagTTCTATGCGCAGCGACAGCGCAGCGGGCACCACGTGATGCGTGGGCGGGCGGCCAATTCGGGTGCggcgcaagcagcagcagccgcggcagcagcggcggcggcagcagcagcagccgcagccatgACAAAtctgcaccagcagcagcagcagcagcagcagcagcagcagcaacaacagcaccagcagcagcagcagcatccgccCATATCGGAGCAGGTGAAATACGCGATCTTGGCGCAGCAGTTGGCACGCAAGGATACGGACTtgctgcagcaggcgctggCGCATGGCTCCAGCAGCGTTGCTGTCAATCCGTTGCTGCACTttggctacaacaacagcagcaacagcagcggcggcaatggcaatggcaatggcaatgggaacagcagcggcagcggcagcaacaacagcagcagcaatgccaatGACAGCAatcagatgcagcagcagcaacaggtgcCCGTGGATGATGATGAGCCGCCCAAGCTGATCATAGACgaggacgatgacgatgatttCGAAGACAtagacgaggaggaggaggaggaggaggaggacgaaGAGCTAGACCAAgacgaacagcagcaggaggaacaGCAaaacgaacagcagcagcaacagcaagtgcAGCCGATTGAAATTGATGCCAAAGacgagccagagccagagccgctCGCCGAGTCGGCGGAGTCGAAACTGAAGCCCAGTGGCGAGCCGACCACAATGAAGAGAATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAAGATGAATCTCAGGATCTGGTGCCGGTAGCGAAGCTGGTGGACAATGCCACTAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGATGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagccGAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAATCGCGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATTCTCACCCACACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATcgagctggaggagcagcGCCGCCGCAAGGCCGCCGAGCAGGAGcgccagctggagctggagcgcgAGCGGGAGCGCGAACGCGAACTGGAGCGGGAGCGTGAGCTGGAGCGCGagcgcaagcagcagcagctcatccaGCAGCTGACGGCAGCGGCTCAGCTCAGCCAGCAAATGGTGGCGGCAGCTCAGGCCGCTCAggttgctgccgccgcagcTGCCACCACCAGCGGCGCTGCAGCCGAGGCCAATGGCAGCGAGCTGCCCTATAAGTGTCACCTGTGCGAGTATTCGTTCGGGGAGCGCATGCAGTGCCTGGACCACatcaagcagcagcacgcccaggagtttgctctgctgctggccaagggCGCCATCGAGACGGAGCAGGaggtggcagcggcagcaagtgcagcaagtgcagcagccacagcgaatgctgcctctgctgccgtCTCTGAGGATGAGTCGAGCACGGGACGCAGCTCCGGCAAATATCCGGACTACAGCAATCGCAAGGTGATCTGCGCTTTCTGCGTGCGCCGCTTCTGGTCCACGGAGGATCTGCGCCGTCACATGCGCACCCACTCGGGCGAGCGTCCGTTCCAGTGCGACATCTGCTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGCCCCAGCCACAATGGGGAGCCGGGCGCCTCCGACTGCTCCGACGATGAGCAAATGGCAACGCCGCCCACAacacccacgcccacggccatgcccatgcccatgcccatgcccatgcctaTGCccagtaacaataacaacaacagcacttaccacaacaacaacaacaacaacaagagcgtGCGTCTGCCCAAGCTGCATGAGCTGCTGGACAAGGCGAACGAATGGCGCGTGAGTCGTCTGGGCGAGCACAAGGAAAACATTGCCGAATCCTCAGCgcccacaacagcagccgctgtgggcgtggccagcggCGATTTCCTGGGCAACCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCCGACGAGGCGGCCAAATTGCTGGGCGTCGAGAAGTGA
Protein Sequence
MLATQQQQQQQPQQQHAAATAATPALTLEEAVMERQRRDSSTSESSLEHLDLGRTPKKLSSNSGALQPTSTPNVEASSRKRKMRQQQQQQQQQFLYSDEEDEQQQQQQQQQQQQQQQLLEQSVHRIRHKQRRSGNAAGNAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDGSAHSGYLLSASAAAQSATAAQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGISAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQHQQHHQQQQQQQQQQQQQQPQQQQSLTQQQQSQPQQQQLQRQQQHSASNQRAESYESDASCSTDISSSSSSAASNNNNNNSQANNNNTEEQRLKLKTNINNNNIIVSDERTLDTDADGDGDGDCDGDGNGNGDRHGEEAGDGESVDVAQMITSTPDVATLLATSSGNSSPRTLEPEQEARCPVCNAGEFETLAALYAHLEAEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPPEEEEEFDEDQHQARLQQQQQLQQQREDQTTAGEDEEEMRLQANSERDEFFQQLYLKGKSGGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSVDGRDCEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDMKPKMDPDLSELSFRSLSPSSSTTNVEASSQLKHMLLAEQPSKQQQQQQQQQQQQQQPQPPLKIQVKSLDQLVEKPLAPAMDLSMDVLDLSKKPQREHDLLVQQQQQQQQQQQQQQQQQQQLLFNQGDAATQYMKLMLMLQQSSGFPFFGLMAPPPAAALEKSAPAIAVPATPATVAAVPPPLGLSLPGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAMTNLHQQQQQQQQQQQQQQHQQQQQHPPISEQVKYAILAQQLARKDTDLLQQALAHGSSSVAVNPLLHFGYNNSSNSSGGNGNGNGNGNSSGSGSNNSSSNANDSNQMQQQQQVPVDDDEPPKLIIDEDDDDDFEDIDEEEEEEEEDEELDQDEQQQEEQQNEQQQQQQVQPIEIDAKDEPEPEPLAESAESKLKPSGEPTTMKRMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAQVAAAAAATTSGAAAEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQEVAAAASAASAAATANAASAAVSEDESSTGRSSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGPSHNGEPGASDCSDDEQMATPPTTPTPTAMPMPMPMPMPMPSNNNNNSTYHNNNNNNKSVRLPKLHELLDKANEWRVSRLGEHKENIAESSAPTTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00599774;
90% Identity
iTF_00516459;
80% Identity
-