Basic Information

Insect: Drosophila aldrichi
Gene Symbol: RREB1
Assembly: GCA_035045965.1
Location: JAWNOM010000484.1:2197697-2204015[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0054 0.4 11.3 0.6 1 21 249 269 249 271 0.96

2 13 0.00031 0.023 15.2 0.2 1 23 281 303 281 303 0.98

3 13 7.5e-05 0.0055 17.1 7.3 1 23 309 331 309 331 0.98

4 13 0.041 3.1 8.5 0.8 2 20 537 555 537 557 0.93

5 13 0.0078 0.57 10.8 0.1 1 23 717 739 717 739 0.97

6 13 1.1e-05 0.00085 19.7 0.7 1 23 749 771 749 771 0.99

7 13 0.00077 0.057 14.0 2.0 1 23 777 800 777 800 0.97

8 13 0.0028 0.2 12.2 2.0 1 23 1055 1078 1055 1078 0.95

9 13 8e-05 0.0059 17.1 0.3 2 23 1405 1426 1404 1426 0.97

10 13 0.13 9.9 6.9 6.3 1 23 1432 1455 1432 1455 0.97

11 13 3 2.2e+02 2.7 4.2 1 23 1582 1605 1582 1605 0.88

12 13 0.0078 0.58 10.8 0.5 3 23 1665 1685 1663 1685 0.96

13 13 0.0013 0.096 13.3 4.8 1 23 1691 1713 1691 1713 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0054	0.4	11.3	0.6	1	21	249	269	249	271	0.96
2	13	0.00031	0.023	15.2	0.2	1	23	281	303	281	303	0.98
3	13	7.5e-05	0.0055	17.1	7.3	1	23	309	331	309	331	0.98
4	13	0.041	3.1	8.5	0.8	2	20	537	555	537	557	0.93
5	13	0.0078	0.57	10.8	0.1	1	23	717	739	717	739	0.97
6	13	1.1e-05	0.00085	19.7	0.7	1	23	749	771	749	771	0.99
7	13	0.00077	0.057	14.0	2.0	1	23	777	800	777	800	0.97
8	13	0.0028	0.2	12.2	2.0	1	23	1055	1078	1055	1078	0.95
9	13	8e-05	0.0059	17.1	0.3	2	23	1405	1426	1404	1426	0.97
10	13	0.13	9.9	6.9	6.3	1	23	1432	1455	1432	1455	0.97
11	13	3	2.2e+02	2.7	4.2	1	23	1582	1605	1582	1605	0.88
12	13	0.0078	0.58	10.8	0.5	3	23	1665	1685	1663	1685	0.96
13	13	0.0013	0.096	13.3	4.8	1	23	1691	1713	1691	1713	0.99

Sequence Information

Coding Sequence: atgCTGgccacacagcagcaacagcagcagcagccacaacagcaacatgcagcagcaacagtagcggcaacagtagcagcagcagcattgacGCTTGAGGATGCGGTTATGGAGCGACAGCGTCGTGACTCTAGCACCTCAGAGTCATCGCTGGAGCATCTGGATCTGGGCCGCACGCCAAAGAAgctgagcagcaacagcggtgCGCTGCAGCCGACGTCGACGCCGAACGTTGAGACGTCTTCGCGGAAGCGCAAgatgcgacagcagcagcaacaacagcaacagacatTCCTCTACTCTGACGAAGAggacgaacagcagcagcaacaacaacaacagcagcagcaacagcaacagctgctggagCAGTCGACGCATCGCATTCGTCACAAGCAGCGCCGCAGCGGCAATGCAGCCGCGGCCGCTGCCAGCGCCAGCATCGTCGTCGACTACAGCGTCGGCAGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGTCTGAAtcgcagcagcatcagcgccCAAAACGGCGACCTCTCCGAGTCGGGCTTCGTCGATGGCAGCTATTTGCTTAGCGCCAGCGCCGCAGCGCAGTCGGCAACggcggcgcagcagcagcagcagcaacaacagcagcagcagcagcagccgggcTCGGGCAGCAGCTCGGGCGGCTCCTCCCCGCAAGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCAGCGCCGGCGACGAGCACATGAAATACGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACAGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCAGCCTCCTCGCTGGACAGACACGTTCTGGTGCACACCGGGGAGCGGCCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACAAATGGCAACATGCATCGGCATATGCGAACACAcaagcaacatcagcaacatcagcaacatcagcagcaacaacagcagcagtcgcagcagccgcagcagcaacagtcaccgcagccacagcagcagcagcaacagttgcagcggCATCAGCAACATGCGGCAGCCAATCAGCGTGCCGAGAGCTATGAAAGCGATGCCAGCTGCTCCACGGATatatccagcagcagcagtagtgcagccagcaacaacaacaacaacaacaacagtagccaagcgaacaacaacaacaacaacaacaatgaggaGCAGCGAGTGAAGCTAAAGacaaacatcaacaacaacaacatcatagTGAGCGACGAGCGAGCGCTGGATGCAGACGCCGATGGCAATGGGGATGGGGATGGGGATGGGGATGGGGATGGAGATGAGGCCGGCGATGGGGAGAGCGTGGATGTGACACAGATGATAACGAGCACACCCGATGTGGCCACATTGCTGGCAACGTCGTcgggcaacagcagcccaAGGACGCTGGAGCCCGAGCTGGAGACGCTGCCCAGATGCCCCGTCTGCCATGCCGGCGAGTTCGAGACGCTGGCCGCGCTGTACGCCCACTTGGAGGCGGAGCACGCCGATATACCCGCCAAGTGTCGTGAGTGCGAGGTGATCTTTGCcacgcagcggcagctgcaggcgCACAGCTGTCGGGGATTGCAGTTGCCACCGTTGCTGGGCGCCAGCTCGTCGCCGCTGCACAAGCAGGAGCCGGcggatgaggaggaggaggagtatgatgaagagcagcagcagcagcaggtgcgcctgcagcagcagcagcgcgacGCTGAGCCGACGgctgaggaggaggaggaggagttgCGCCTGCAGGCGAACAGCGAGCGTGATGAGTTCTTTCAGCAGCTTTACCTCAAGGGCAAGTCGGGCGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGACCTGGCCGACATACAGAGCATCCTGCACAtgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTCAATACGCCCTGCTCCAGCCAGTATAGCCTGGATGGGCGCGACGGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAATTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAACTCTGCACCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAACCGCGTCCACCTGGCGGCCGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCTCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGCCACCTGCGCAATCGGCACGGCAAGACGAGCCGCGACGAGGTGAAGCGCGCGATCGTCTATCACCCGGCCGAGGATGCCAGCTGCGAGGACATCAAGCCCAAGCTGGATCCCGATCTGTCGGAGCTCAGCTTTCGCTCGCTCAGTCCGTCGCCATCGACGACCAATGTGGAGGCGAGCTCCCAGCTGAAGCACATGTTGCTGGCAGAGCAGCccagcaagcagcaacagcagcagcagcaacagcagcaatcgtCGCAGCCTCCGCTGAAGATTCAAGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTGGCACCTGCCATGGATCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAACGCGAACATGACTTACtcgtgcagcaacagcagcaacagcaacagcagcaacagcaacaacagcagcagcagcagcagcaacagcagcaacagcaacagttgctcttCAATCCGGGCGATGCAGCGACACAGtatatgcagctgctgcgcaatCTGATGCTGCAGCAGTCGTCCAGCTTTCCGTTCTTTGGGCTGATGGCGCCAccgccagctgctgcgctgGAGAAGTCAGCGCCAGCGACGATTGCAGTGCCAGCGACGccggcaacagttgctgccgtgCCGCAGCCCCTGGGCCTGCCCTTGCACGGCATGGGCGTGCCGGTGCCAGCCGCCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGCccaagcagaagcagcgcCGCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCGGCCAGGTTCACGCTGCGCTCCAACATGGAGCGCCACgtcaagcagcagcatccgcaGTTCTATGCGCAGCGACAGCGCAGCGGGCACCACGTGATGCGCGGCCGTGCAGCCAATTCGGGTGCGGCtcaagcagcagcggccgcagcagcagcggcggcggcagcagcagcagccgcagcagccatgACAAAtctgcaccagcagcagcaccaacagcagcaacatccgcCCATCTCGGAGCAGGTGAAGTACGCGATCTTGGCGCAGCAGTTGGCGCGCAAGGATACGGATTTGCTGCAGCAGGCGCTGGCTCATGGTTCCAGCAGCGTTGCCGTCAATCCGTTGCTGCACTttggctacaacaacaacagcggcagcagcggcaacggcagcagcaacagcaatgccaatggcagcaatcaggcgcagcagcagcaacagttgcccgTGGATGATGATGAGCCGCCCAAGTTGATCATAGACgaggacgatgacgatgatttCGAGGACAtagacgaggaggaggaggaggaagaagaCGAAGAGCTAGACCAAgacgagcaacagcagcagcagcaggagcagcaacacgagcaacagcaacagcgtgTGGAGCAAGTGCAGCCAATTGAGATTGATGCCAAAGAGGAGCCAGAGCCGCTCGCCGAATCGGCCGAGTCGAAGCCCAGTGGTGGCGAGCCGAGCACCATGAAGACAATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCGAAGCTGGTGGACAATGCCACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGTCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgaacCGAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAATCGCGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATTCTCACCCACACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCAAGGCCGCCGAGCAGGAGcgccagctggagctggagcgcgAGCGTGAACGCGAACGCGAACTGGAGCGGGAGCGTGAGCTGGAGCGCGagcgcaagcagcagcagctcatccAGCAGCTAACAGCGGCGGCTCAGCTCAGCCAGCAGATGGTGGCCGCAGCTCAGGCTGCTCAGgtcgctgccgccgcagcagccacCACCAGCGGCACAAGCGGCACAAGCGGCATCAGCGGCGCTGCAGCCGAGGCCAATGGCAGCGAGCTGCCCTACAAGTGTCACCTGTGCGAGTATTCGTTCGGCGAGCGCATGCAGTGCCTGGACCACATCAAACAGCAGCACGCCCAGGAgtttgctctgctgctggccaagggCGCCATCGAGACGGAGCAGGaggtggcagcggcagcggcagcaaccgcagcagcgaATGCTACCTCTGCTGCCGTCTCCGAGGATGAGTCCAGCACGGGCCGCAGCTCTGGCAAGTATCCGGACTATAGCAATCGCAAGGTGATCTGCGCCTTTTGCGTGCGTCGCTTCTGGTCCACAGAGGATCTGCGCCGTCACATGCGCACCCACTCGGGCGAGCGTCCGTTCCAGTGCGACATCTGTTTGCGCAAGTTCACGCTGAAGCATAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCCACAATGGTGAGCCAGGTGCCTCCGATTGCTCCGATGATGAGCAAATGGCAACGCCGCCCACAACACCAACGCCCACGGCCACGGCCACGGCCATGCccatgccaatgccaatgcccagcaacaacaacaacaacaacaacacttgccacaacaacaacaacaccaacagtaacaacaacaacaacaacaacaagagcgtACGTCTGCCCAAGCTGCACGAACTGTTGGACAAGGCGAACGAATGGCGCGTCAGTCGCCTGGGCGAGCACAAGGAAAACATTGCCGAATCCTCAGCGCCCACCACAGCTgccgctgtgggcgtggccagcggTGATTTCCTGGGCAATCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCCGACGAGGCGGCCAAATTGCTGGGCGTCgagaagtga
Protein Sequence: MLATQQQQQQQPQQQHAAATVAATVAAAALTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSNSGALQPTSTPNVETSSRKRKMRQQQQQQQQTFLYSDEEDEQQQQQQQQQQQQQQLLEQSTHRIRHKQRRSGNAAAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAQNGDLSESGFVDGSYLLSASAAAQSATAAQQQQQQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGISAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQHQQHQQQQQQQSQQPQQQQSPQPQQQQQQLQRHQQHAAANQRAESYESDASCSTDISSSSSSAASNNNNNNNSSQANNNNNNNNEEQRVKLKTNINNNNIIVSDERALDADADGNGDGDGDGDGDGDEAGDGESVDVTQMITSTPDVATLLATSSGNSSPRTLEPELETLPRCPVCHAGEFETLAALYAHLEAEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPADEEEEEYDEEQQQQQVRLQQQQRDAEPTAEEEEEELRLQANSERDEFFQQLYLKGKSGGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKLDPDLSELSFRSLSPSPSTTNVEASSQLKHMLLAEQPSKQQQQQQQQQQSSQPPLKIQVKSLDQLVEKPLAPAMDLSMDVLDLSKKPQREHDLLVQQQQQQQQQQQQQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSSSFPFFGLMAPPPAAALEKSAPATIAVPATPATVAAVPQPLGLPLHGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAAMTNLHQQQHQQQQHPPISEQVKYAILAQQLARKDTDLLQQALAHGSSSVAVNPLLHFGYNNNSGSSGNGSSNSNANGSNQAQQQQQLPVDDDEPPKLIIDEDDDDDFEDIDEEEEEEEDEELDQDEQQQQQQEQQHEQQQQRVEQVQPIEIDAKEEPEPLAESAESKPSGGEPSTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAQVAAAAAATTSGTSGTSGISGAAAEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQEVAAAAAATAAANATSAAVSEDESSTGRSSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRHNGEPGASDCSDDEQMATPPTTPTPTATATAMPMPMPMPSNNNNNNNTCHNNNNTNSNNNNNNNKSVRLPKLHELLDKANEWRVSRLGEHKENIAESSAPTTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599774;
90% Identity: iTF_00516459;
80% Identity: -