Basic Information

Insect: Drosophila mulleri
Gene Symbol: RREB1
Assembly: GCA_035047565.1
Location: JAWNPK010000093.1:440607-447825[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0054 0.42 11.3 0.6 1 21 249 269 249 271 0.96

2 13 0.00031 0.024 15.2 0.2 1 23 281 303 281 303 0.98

3 13 7.5e-05 0.0058 17.1 7.3 1 23 309 331 309 331 0.98

4 13 0.094 7.3 7.4 0.9 2 20 539 557 539 559 0.93

5 13 0.0078 0.6 10.8 0.1 1 23 721 743 721 743 0.97

6 13 1.1e-05 0.00088 19.7 0.7 1 23 753 775 753 775 0.99

7 13 0.00077 0.059 14.0 2.0 1 23 781 804 781 804 0.97

8 13 0.0028 0.21 12.2 2.0 1 23 1059 1082 1059 1082 0.95

9 13 8e-05 0.0062 17.0 0.3 2 23 1421 1442 1420 1442 0.97

10 13 0.13 10 6.9 6.3 1 23 1448 1471 1448 1471 0.97

11 13 3 2.3e+02 2.7 4.2 1 23 1595 1618 1595 1618 0.88

12 13 0.0078 0.6 10.8 0.5 3 23 1684 1704 1682 1704 0.96

13 13 0.0013 0.1 13.2 4.8 1 23 1710 1732 1710 1732 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0054	0.42	11.3	0.6	1	21	249	269	249	271	0.96
2	13	0.00031	0.024	15.2	0.2	1	23	281	303	281	303	0.98
3	13	7.5e-05	0.0058	17.1	7.3	1	23	309	331	309	331	0.98
4	13	0.094	7.3	7.4	0.9	2	20	539	557	539	559	0.93
5	13	0.0078	0.6	10.8	0.1	1	23	721	743	721	743	0.97
6	13	1.1e-05	0.00088	19.7	0.7	1	23	753	775	753	775	0.99
7	13	0.00077	0.059	14.0	2.0	1	23	781	804	781	804	0.97
8	13	0.0028	0.21	12.2	2.0	1	23	1059	1082	1059	1082	0.95
9	13	8e-05	0.0062	17.0	0.3	2	23	1421	1442	1420	1442	0.97
10	13	0.13	10	6.9	6.3	1	23	1448	1471	1448	1471	0.97
11	13	3	2.3e+02	2.7	4.2	1	23	1595	1618	1595	1618	0.88
12	13	0.0078	0.6	10.8	0.5	3	23	1684	1704	1682	1704	0.96
13	13	0.0013	0.1	13.2	4.8	1	23	1710	1732	1710	1732	0.99

Sequence Information

Coding Sequence: atgCTGgccacacagcagcaacagcagcagcagccacaacagcaacatgcagcaacaacagcagcggcagcggcagcagcattgACGCTTGAGGATGCTGTTATGGAGCGACAGCGTCGTGACTCCAGCACCTCAGAGTCATCGCTGGAGCATCTGGATCTGGGTCGCACGCCAAAGAagctgagcagcaacagcggtgCGCTGCAgccgacgtcgacgccgaACGTTGAGGCGTCTTCGCGGAAGCGCAAgatgcgacagcagcagcagcaacagcaacagccattcCTGTACTCTGACGAGGAggacgaacagcagcagcagcagcagcaacagcaacagcagcaacagcaacagctgctggagcagtcGGTGCAACGCATTCGCCACAAGCAGCGCCGCAGCGGCAATGCAGCCGCGACcgctgccagcgccagcgccagcatcGTCGTCGACTACAGCGTCGGCAGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGCCTGAAtcgcagcagcatcagcgccCACAACGGCGACCTCTCCGAGTCGGGCTTCGTCGATAGCAGCGCGCACAGCGGCTATTTGCTTAGCGCCAGCGCCGCAGCGCAGTCCGCAACggcggcgcagcagcagcagcaacagcagcagccgggcTCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAAGGCCTGTGCCATTCGAGCGCCGAATCCGGCATCAGCGCCGGCGACGAGCACATGAAATATGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACAGAGAACTTCACCTGCCGCATCTGCTCTAAGGTACTCTCGTCAGCGTCCTCGCTGGACAGACACGTGCTGGTGCACACCGGGGAGCGGCCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACAAACGGCAACATGCATCGGCACATGCGAACACAcaagcaacatcagcaacatcagcagcagcagcagcaacaacagcagccgcagcagctgcaagcgctgacacagcagcaacagtcgcagcagccacagcagcagcaacagttgcagcggCATCAGCAGCATTCGGCAGCCAATCAGCGTGCCGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGATatatccagcagcagcagcagtgcagccagcaacaacaacaacaacagtagccaagcgaacaacaacaacaataacaataacaatgaggAGCAGCGACTGAAACTAAAGACAaacatcaataacaacaacatcatagTCAGCGACGAGCGAGCGCTGGATACAGACGCCGATGGCAATGGGGATAGggatgggcatgggcatgagGATGGAGATGGAGACGGAGAGGAGGCCGGCGATGGGGAGAGCGTGGATGTGACACAGATGATAACGAGCACACCCGACGTGGCCACATTGCTGGCGACATCGTCGGGCAACAGCAGCCCGAGGACGCTGGAGCCCGAGCTGCCCAGTTGCCCCGTCTGCAATGCCGGCGAGTTCGAGACGCTGGCCGCGATGCTCGCCCACTTGGAGGCGGAGCACGCCAATATACCCGCCAAGTGTCGCGATTGCGAGGTGATCTTTGGCacacagcggcagctgcaggcgcACAGCTGTCGGGGATTGcagttgccgccgctgctgggCGCCAGCTCGTCGCCGCTGCACAAGCAGGAGCCGGCAGAAGAGGCGGAGGAGTATgatgaggagcagcagcagcaggtgcgcctgcagcatcagcatcagcagcagcaacgcgaCGCTGAGCCGACGGctgaggaggaggacgaggagaTGCGCCTGCAGGCGAACAGCGAGCGGGACGAGTTCTTTCAGCAGCTTTACCTCAAGGGCAAGTCGGGCGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGACCTGGCCGACATACAGAGCATCCTGCACAtgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAATGTCAATACGCCCTGCTCCAGCCAGTACAGCCTGGATGGGCGCGACGGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAATTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAACTCTGTACCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAACCGCGTCCACCTGGGAGCCGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCTCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGCCACCTGCGCAATCGGCACGGCAAGACGAGCCGCGACGAGGTGAAGCGCGCGATTGTCTATCACCCGGCCGAGGACGCCAGCTGCGAGGACATCAAGCCCAAGATGGATCCCGATCTGTCGGAGCTCAGCTTTCGCTCGCTCAGTCCGTCGCCGTCGACGACCAATGTGGAGGCGAGCTCCCAGCTGAAGCACATGTTGCTGGCGGAGCAGcccagcaagcagcagcaaccgtcgcagcaacagcagcaaccgaCACAGCAGCAACCGTCGCAGCCTCCGTTGAAGATTCAAGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCAGGCACCTGCCATGGATCTCAGCATGGATGTGTTGGATCTCAGCAAGAAGCCGCAACGCGAACATGACTTActcgtgcagcagcagcaacagcagcagcagcagcaacagcaacagcagcaacaacagcagcagcagcaacagttgctcttCAATCCGGGCGATGCAGCGACGCAGTatatgcagctgctgcgcaatCTGATGCTGCAGCAGTCGTCCGGCTTTCCGTTCTTTGGGCTGATGGCGCCAccgccagctgctgcgctgGAGAAGTCAGCGCCAGCGATTGCAGTGCCAGCGACgccggcaacagttgctgccgtgCCGCAGCCTCTGGGCCTGCCCTTGCCCGGCATGGGCGTGCCAGTGCCAGCGGCCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGcccaagcagaagcagcgccGCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCGGCCAGGTTCACGCTGCGCTCCAACATGGAGCGCCACgtcaagcagcagcatccgcagTTCTACGCGCAGCGACAGCGCAGCGGGCACCACGTGATGCGCGGCCGGGCGGCCAATTCGGGTGCagcgcaagcagcagcagccgcggcagcagcagcggcggcagcagcagccgcagcagccatgACTAAtctgcaccagcagcagcagcaacagcagcagcacccgcCCATATCGGAGCAGGTGAAGTACGCGATCTTGGCGCAACAGTTGGCGCGCAAGGATACGGACTtgctgcagcaggcgctggCCCATGGCTCCAGCAGCGTCGCCGTCAATCCCTTGCTGCACTttggctacaacaacaacagcggcagcagcagcagcggcaacggcaacggcaacggcagctgcagcagcaacagcaacggcaatgccaatggcagcaatcaggcgcagcagcagcaacagttgcccgTGGATGATGATGAGCCGCCCAAGCTGATCATagacgaggacgacgacgatgatttCGAAGACAtagacgaggaggaggaggaggaggaggacgaagAGCTAGACCAAgacgagcaacaacagcagcagcaacagcagcaggcggagcagcaacacgagcagcagcaacagcgtgTGGAGCAAGTGCagccaattgaaattgatgccAAAGAGGAGCCAGAGCCGCTCGCCGAGTCGGCCGAGTCGAAGCCCAGTGGCGAGCCGAGCACAATGAAGACAATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTAGCGAAGCTGGTGGACAATGCCACTAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgaacCGAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAATCGGGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATTCTCACCCACACGGGCCAGAAGCCATTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGTCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCAATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCAAGGCCGCCGAGCAGGAGcgccagctggagctggagcgcgAGCGTGAGCGCGAACGCGAACTGGAGCGGGAGCGTGAGCTGGAGCGCGagcgcaagcagcagcagctcatccaGCAGCTGACGGCGGCGGCTCAGCTCAGCCAGCAGATGGTGGCCGCAGCCCAAGCTGCACAGGTCGCTGCCGCCGCGGCAGCCACcaccagcgccagcagcggcagcagcggcgctgcAGCCGAGGCCAATGGCAGCGAGCTGCCGTACAAGTGTCACCTGTGCGAGTACTCGTTCGGCGAGCGCATGCAGTGCCTGGACCACatcaagcagcagcacgcccaggagtttgctctgctgctggccaagggCGCCATCGAGTCGGAGCAGGaggtggcagcaacagcagcggcagcggcagcgtcagcaacagcagcgacagcgaatgctgcctctgctgccgtCTCCGAGGACGAGTCCAGCACGGGACGCAGCTCTGGCAAGTATCCGGACTACAGCAATCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACGGAGGATCTGCGCCGTCACATGCGCACCCACTCGGGCGAGCGTCCGTTCCAGTGCGACATCTGCTTGCGCAAGTTCACACTGAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGCGGACGCCACAATGGCGAGCCGGGCGCCTCCGATTGCTCCGATGATGAGCAAATGGCAACGCCGCCCACAACACCAACGCCCACGTCCACGCCCAtggccatgcccatgcccatgcccatgccagtgccagtgcccagcaacaacaataacaacaacaacacttgccacaacaacaacaataacaacaacagcaagagcgtACGTCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAATGGCGCGTCAGCCGCCTGGGCGAGCACAAGGAAAACATTGCCGAATCCTCAGCGCCCACAACAGCTgccgctgtgggcgtggccagcggTGATTTCCTGGGCAATCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCCGACGAGGCGGCCAAACTGCTGGGCGTCGAGAAGTGA
Protein Sequence: MLATQQQQQQQPQQQHAATTAAAAAAALTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSNSGALQPTSTPNVEASSRKRKMRQQQQQQQQPFLYSDEEDEQQQQQQQQQQQQQQQLLEQSVQRIRHKQRRSGNAAATAASASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDSSAHSGYLLSASAAAQSATAAQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGISAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQHQQQQQQQQQPQQLQALTQQQQSQQPQQQQQLQRHQQHSAANQRAESYESDASCSTDISSSSSSAASNNNNNSSQANNNNNNNNNEEQRLKLKTNINNNNIIVSDERALDTDADGNGDRDGHGHEDGDGDGEEAGDGESVDVTQMITSTPDVATLLATSSGNSSPRTLEPELPSCPVCNAGEFETLAAMLAHLEAEHANIPAKCRDCEVIFGTQRQLQAHSCRGLQLPPLLGASSSPLHKQEPAEEAEEYDEEQQQQVRLQHQHQQQQRDAEPTAEEEDEEMRLQANSERDEFFQQLYLKGKSGGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKMDPDLSELSFRSLSPSPSTTNVEASSQLKHMLLAEQPSKQQQPSQQQQQPTQQQPSQPPLKIQVKSLDQLVEKPQAPAMDLSMDVLDLSKKPQREHDLLVQQQQQQQQQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSSGFPFFGLMAPPPAAALEKSAPAIAVPATPATVAAVPQPLGLPLPGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAMTNLHQQQQQQQQHPPISEQVKYAILAQQLARKDTDLLQQALAHGSSSVAVNPLLHFGYNNNSGSSSSGNGNGNGSCSSNSNGNANGSNQAQQQQQLPVDDDEPPKLIIDEDDDDDFEDIDEEEEEEEDEELDQDEQQQQQQQQQAEQQHEQQQQRVEQVQPIEIDAKEEPEPLAESAESKPSGEPSTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAQVAAAAAATTSASSGSSGAAAEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIESEQEVAATAAAAAASATAATANAASAAVSEDESSTGRSSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRHNGEPGASDCSDDEQMATPPTTPTPTSTPMAMPMPMPMPVPVPSNNNNNNNTCHNNNNNNNSKSVRLPKLHELLDKANEWRVSRLGEHKENIAESSAPTTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512904;
90% Identity: iTF_00516459;
80% Identity: -