Basic Information

Insect: Drosophila buzzatii
Gene Symbol: RREB1
Assembly: GCA_035045845.1
Location: JAWNOS010000596.1:3871742-3878302[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0027 0.21 12.3 1.0 1 21 240 260 240 262 0.96

2 12 0.00032 0.025 15.2 0.2 1 23 272 294 272 294 0.98

3 12 7.8e-05 0.0061 17.2 7.3 1 23 300 322 300 322 0.98

4 12 0.043 3.4 8.5 0.8 2 20 521 539 521 541 0.93

5 12 0.0081 0.63 10.8 0.1 1 23 696 718 696 718 0.97

6 12 1.2e-05 0.00093 19.7 0.7 1 23 728 750 728 750 0.99

7 12 0.0008 0.063 14.0 2.0 1 23 756 779 756 779 0.97

8 12 0.0029 0.22 12.2 2.0 1 23 1040 1063 1040 1063 0.95

9 12 8.3e-05 0.0065 17.1 0.3 2 23 1395 1416 1394 1416 0.97

10 12 0.14 11 6.9 6.3 1 23 1422 1445 1422 1445 0.97

11 12 0.0081 0.64 10.8 0.5 3 23 1652 1672 1650 1672 0.96

12 12 0.0013 0.1 13.3 4.8 1 23 1678 1700 1678 1700 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0027	0.21	12.3	1.0	1	21	240	260	240	262	0.96
2	12	0.00032	0.025	15.2	0.2	1	23	272	294	272	294	0.98
3	12	7.8e-05	0.0061	17.2	7.3	1	23	300	322	300	322	0.98
4	12	0.043	3.4	8.5	0.8	2	20	521	539	521	541	0.93
5	12	0.0081	0.63	10.8	0.1	1	23	696	718	696	718	0.97
6	12	1.2e-05	0.00093	19.7	0.7	1	23	728	750	728	750	0.99
7	12	0.0008	0.063	14.0	2.0	1	23	756	779	756	779	0.97
8	12	0.0029	0.22	12.2	2.0	1	23	1040	1063	1040	1063	0.95
9	12	8.3e-05	0.0065	17.1	0.3	2	23	1395	1416	1394	1416	0.97
10	12	0.14	11	6.9	6.3	1	23	1422	1445	1422	1445	0.97
11	12	0.0081	0.64	10.8	0.5	3	23	1652	1672	1650	1672	0.96
12	12	0.0013	0.1	13.3	4.8	1	23	1678	1700	1678	1700	0.99

Sequence Information

Coding Sequence: atGCTggccacacagcagcagcagcagcagcagccacagcagcaacatgcagcagcagcagcagcagcagcggcagtgaCTCTTGAGGATGCGGTTATGGAGCGACAGCGACGTGACTCCAGCACCTCGGAGTCGTCGCTGGAGCATCTGGATCTGGGTCGCACGCCAAAGAAGCTGAGCAGCAATAGCGGTGCGTCGATGCCGACGTCGACGCCGCATGTCGAGTCGACGTCGCGAAAGCGCAAGatgcagcgacagcagcagcagcagcaaatcttGTACTCTGACGAGGAGgacgagcaacagcagcaacagcagcagcagcagcagcagcagcaacagttgctggaACAGTCGGTGCAACGCAATCGCCATAAGCAGCGCCGCAGCGGCAGTGCAGTCGCGGCCGCTGCCAGCGCCAGCATCGTCGTCGACTACAGCGTCGGCAGCGATGCCAGCTCGCTGCGCAAAAAGTTTCGCCTGAATCGCAGCAACATCAGCGCCCACAACGGCGACCTCTCCGAGTCGGGCTTCGTCGATGGCAGCGCACACAGCGGCTTTTTGCTCAGTGCCAGCGGCGCAGCGCAGTCGGCGACGAccgcgcagcagcagcaacagcagccgggCTCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAAGGCCTCTGCCATTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACAGAAAATATGTCTGCCCCATCTGCGAGGTCGTCTCGACCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATTTGCTCCAAGGTACTCTCTTCAGCCTCCTCGCTGGACAGACACGTCCTGGTGCATACCGGGGAGCGACCCTTTAATTGTCGCTATTGCCATTTGACCTTCACGACAAATGGCAACATGCATCGGCACATGCGAACACAcaagcagcatcaacagcagcagcagcagcagcagcagcagcagcaacaacagcagcagcaacaacagcagcagcagcaacagccgcagccgcaacaGTTGCAGCGACATCAGCAACATGTGGCATCAAATGCTGTGGGTCAGCGTGCCGAGAGCTATGAAAGCGATGCCAGTTGCTCCACGGATAtatccagcagcagcagcagtgcaaccagcaacaacaacaacaacagtagccaagcgaacaacaacaacaacaatgaggaGCAGCAACTGAAGCTAAAgaccaacatcaacaacaacaacatcattgTCAGCGACGAGCGAGCACTGAACATGGACgccgatggcgatggcgatggcgatggcgatgtgGAGGAGGCAGCGGATGGCGAAAGCGTGGATGTGACACAGATGATAACGAGCACACCCGACGTGGCCACGCTGCTGGCAACATCGTCGGGCAACAGCAGCCCGCGAACGCCGGAGCCCGAGTCGGAGGCGTTGCCCAGCTGCCCCGTCTGCAATGCCGGCGAGTTCGAGACGCTGGCCGCGCTGTACGCCCACCTGGAGGCGGAGCACGCCGATATACCCGCCAAGTGTCGGGAGTGCGAGGTGATCTTTGCCacgcagcggcagctgcaggCGCACAGCTGTCGGGGATTGCagttgccgccgctgctggGCGCCAGCTCATCGCCGCTGCACAAGCAGGAGCCGGcggaggaggaggatgaggagcagcagttgcaacagcagcagcagcagcagcagcgcgatGACGAGGCCGAGGCTGAGGAGGACGAGGAGGAGATGCGCCTGCAAGCGAACAGCGAGCGCGACGAGTTCTTTCAGCAGCTGTATCTCAAGGGCAAGTCGAGCGGCTCCTCGCTGCCGTCGCCCATCAAGCATGAGCCGACGGAGCAGCGCCAGGACCTGGCCGACATACAGAGCATACTGCATATgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTGAACACGCCCTGCTCCAGCCAGTACAGCGTGGATGGGCGCGACGGCGAGGAGGAGGCCCAGGATGCCTTCACCAGCGAGTTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCACCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTGGCAGCCGTCGGTGCCGCCGGCCCCTTTCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGTGAGCGCCATCTGCGTAATCGGCACGGCAAGACGAGCCGCGACGAGGTGAAGCGCGCGATCGTCTATCACCCGGCCGAGGATGCCAGCTGCGAGGACATCAAGCCCAAGATGGATCCCGATCTGTCGGAGCTCAGCTTTCGCTCACTCAGTCCCGCGCCCTCGATGACCAATGTGGAGCCGAGCTCCCAGCTGAAGCACATGTTGCTGGCCGATCAGcccagcaagcagcagcagcagcaacagcagcaacagcagcagcagcagcagtcgcagtcgcagtcgcagccgcagcctcCATTGAAGATTCAGGTAAAGAGCTTGGATCAGCTGGTGGAGAAGCCACTGGCACCTGCCGTGGATCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAACGCGAACATGACTTActcttgcagcagcagcagcaacagcagcagcagcagcagcagcagcaacaacagcagcagcagcagcagcagcaacagttgctcttCAATCCAGGCGATGCAGCGACGCAGTATATGCAGCTGTTGCGCAATCTGATGCTGCAGCAGTCACCCGGCTTTCCGTTCTTTGCGCTGATGGCGCCACCGCCAGCTGCTGCGCTGGAGAAGTCAGCGCCAGCGCTTGCGGTGCCAGCGAcgccagcaacagttgctgcaggGCCGCCGCCACTGGGCCTGCCCTTGAGCGGCATGGGCGTGCCAGTGCCAGCGGCTGGCCCGGTCAAGATGGTCATCAAGAACGGCGTGCTGATGcccaagcagaagcagcgtCGCTACCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCGGCCAGATTCACGCTGCGCTCCAACATGGAGCGCCATgtcaagcagcagcatccgCAGTTCTATGCGCAGCGACAGCGCAGCGGGCATCACGTGATGCGTGGGCGTGCGGCCAACTCGGGTGCggcccaagcagcagcagcagcggcggcagcggcagcagcagcagcagccgcagcagcagccatgacAAAtctgcaccagcagcagcagcagcagcagcagcccataTCGGAGCAGGTGAAGTACGCGATCCTGGCACAGCAATTGGCGCGCAAGGAAACGGATTTGTTGCAGCAAGCGCTGGCTCATGGCTCCAGCAGCGTGGCCGTCAATCCGCTGCTGCActtcaactacaacaacaacagcaacaacaacaacaacaacatcagcagcagcgatgTCAATGGCAATAAtcaggcgcagcagcaacagttgcccgTGGATGATGATGAGCCGCCGAAGCTGATTATAGATGAGGACGATGACGATGAGTTCGATGACATAgatgaggaggaggaagaggaggaggacgaGGAGCTAGACCAAgacgagcaacagcagcagcagcaggaggagcaacagcagcaagagcaacagccacagcaacagcaacagcaacgtgTGGAGCAAGTGCagccaattgaaattgatgcgAAAGATGAGCCAGAGCCGCTCGCCGAGCCGATCGAGCCGAAAGCGAAGCCCAGCGGCGAGCCGTCGACAATGAAGACTATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGTAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagccGAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAATCGCGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGGCGTCACATCCTCACACACACGGGCCAGAAGCCATTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAACGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCAAGGCCGCCGAGCAGGAGCGCCAGCTCGAGCTGGAGCGGGAGCGCGAGCGCGAACGTGAGCTGGAGCGGGAGCGTGAGCTGGAACGCGAgcgcaagcagcagcagctcatccaGCAACTGACGGCGGCGGCTCAGCTCAGCCAGCAGATGGTGGCCGCAGCTCAGgccgctgccgcagcagctgccaccagcagtggcaacagcggcagcagcagcgctgcaCCCGAGACCAATGGCAGCGAGCTGCCCTACAAGTGTCACCTGTGCGAGTATTCGTTCGGGGAGCGCATGCAGTGCCTCGACCACATCAAGCACCAGCACGCCCAGGAGtttgcgctgctgctggccaagggCGCCATCGAGACGGAGCAggagctggcagcagcagcagcagcaacagcagtcacCACAGCAAATGCCACAGTCTCGGCTGGCGTCTCCGAGGATGAGTCCAGCACGGGCCGCAGCGCCGGCAAATATCCGGACTACAGCAATCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACCGAGGATCTGCGCCGTCACATGCGCACCCACTCGGGAGAGCGTCCGTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACACAGTCACAATGGCGAGCCGGGCGCCTCCGATTGCTCCGATGACGAGCAGATGGCAACGCCGCCCACAACACCAACACCCACggccatgcccatgcccatgcccatgccaatgcccagcaacaacaacaacaacaacaacacttgccacaacaacaacaacaacagtaagaGCGCGCGTCCGCCCAAGCTGCACGAGCTGCTGGACAAGACGAACGAGTGGCGCGCCAGTCGCCTCGGCGAGCACAAGGAGAACATTGCCGAACCCTCGGCGCCCGCAACAGCAATTgccgtgggcgtggccagcggCGATTTCCTGGGCAATCTGCTCGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCACCCGACGAGGCAGCCAAACTGCTGGGCGTCGAGAAGTGA
Protein Sequence: MLATQQQQQQQPQQQHAAAAAAAAAVTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSNSGASMPTSTPHVESTSRKRKMQRQQQQQQILYSDEEDEQQQQQQQQQQQQQQLLEQSVQRNRHKQRRSGSAVAAAASASIVVDYSVGSDASSLRKKFRLNRSNISAHNGDLSESGFVDGSAHSGFLLSASGAAQSATTAQQQQQQPGSGSSSGGSSPQGLCHSSAESGIGAGDEHRKYVCPICEVVSTTPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQQQQQQQQQQQQQQQQQQQQQQPQPQQLQRHQQHVASNAVGQRAESYESDASCSTDISSSSSSATSNNNNNSSQANNNNNNEEQQLKLKTNINNNNIIVSDERALNMDADGDGDGDGDVEEAADGESVDVTQMITSTPDVATLLATSSGNSSPRTPEPESEALPSCPVCNAGEFETLAALYAHLEAEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPAEEEDEEQQLQQQQQQQQRDDEAEAEEDEEEMRLQANSERDEFFQQLYLKGKSSGSSLPSPIKHEPTEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSVDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKMDPDLSELSFRSLSPAPSMTNVEPSSQLKHMLLADQPSKQQQQQQQQQQQQQQSQSQSQPQPPLKIQVKSLDQLVEKPLAPAVDLSMDVLDLSKKPQREHDLLLQQQQQQQQQQQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSPGFPFFALMAPPPAAALEKSAPALAVPATPATVAAGPPPLGLPLSGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAAMTNLHQQQQQQQQPISEQVKYAILAQQLARKETDLLQQALAHGSSSVAVNPLLHFNYNNNSNNNNNNISSSDVNGNNQAQQQQLPVDDDEPPKLIIDEDDDDEFDDIDEEEEEEEDEELDQDEQQQQQQEEQQQQEQQPQQQQQQRVEQVQPIEIDAKDEPEPLAEPIEPKAKPSGEPSTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVNEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAAAAAATSSGNSGSSSAAPETNGSELPYKCHLCEYSFGERMQCLDHIKHQHAQEFALLLAKGAIETEQELAAAAAATAVTTANATVSAGVSEDESSTGRSAGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGHSHNGEPGASDCSDDEQMATPPTTPTPTAMPMPMPMPMPSNNNNNNNTCHNNNNNSKSARPPKLHELLDKTNEWRASRLGEHKENIAEPSAPATAIAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512904;
90% Identity: iTF_00516459;
80% Identity: -