Dfic003452.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ficusphila
Gene Symbol
-
Assembly
GCA_018152265.1
Location
JAECXK010000407.1:15397466-15399662[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.015 1.1 9.7 0.9 1 23 332 355 332 355 0.97
2 10 0.54 38 4.9 0.2 6 23 365 382 365 382 0.98
3 10 1.3e-05 0.00095 19.4 0.4 1 23 388 410 388 410 0.98
4 10 0.00039 0.028 14.7 0.4 1 19 425 443 425 443 0.90
5 10 0.00027 0.019 15.3 0.7 1 23 456 479 456 479 0.97
6 10 3.3e-05 0.0024 18.1 1.6 3 23 487 508 485 508 0.92
7 10 0.0011 0.076 13.4 0.4 2 23 520 542 519 542 0.97
8 10 0.00055 0.039 14.3 7.1 1 23 549 572 549 572 0.93
9 10 2.4e-06 0.00017 21.7 0.8 1 23 578 600 578 600 0.98
10 10 6.8e-05 0.0048 17.1 1.3 1 23 606 629 606 629 0.97

Sequence Information

Coding Sequence
ATGGCGACCTGTGTGCTCTGTTTGACGAGCTCTGAATCTGCTTACGGACTGGAGTCGGCGGAGGGCGTCCGGCTGAAAATAAGGGCGACCATCAGCAAACATTTTTCATTTTCAGAGGTCCATTCAGCGGGTAGTGATGCGTCGGTCTGTCGGGAGTGCTGGGACTGTGTCAGCAGTTTCGAGGAGTTCCACCAGCGTGTATCCCGCCTGCACCAGGAGAGGAGCAGCGACTCCAAGAGCGTGCCCATCGAATTCTGCGGCCAGGCAGAGGAGGCTATTAATCCGCTGTACTCCGTGGAACTGGACGCCCTGGCCGAGGGCTTCTTTGCGCCCAATGAGGTCAAGGTGGAGGTGAACGAACTGGAACCTCTGCCGAAAGTGGAACTTCTGGAGGATCCAGTTAACACGGAAACAAGAACAGCCTCCAAGCGGCTGGGTGACCAAAACGACGGATTACACCACCCAAAGCGACGCATTAAAAACGAACAAGCAGTCGACAGTGATTCGGATGTACCTCTAGCGGATTTTCTGTCCTCAGACATTAAGAGCAGCTCCAATGGACCAGATAAGGATAACGAACCGACCAAGGGCCGTCCGCTACGAAGAAGCACAAGACGTGGACGTCCGCCCAAGCCAAAACCGGAGTTGCATGCTTCTCCCAAAAAAGAACCTGATTCCGATGAGGACGATGACGATGTTGCTTCGAGGGAAAATGACATGGAGTTCGTACCTCCCGAGGCTGTTCTGGGCACAGAAGATAGCGCTAGCTCCTCCAGTGAAAGCAGTGGCGAGGACTCGGACCACAGTCTGCCGGACATTGAGCCCGAAGAACGCTACGCCGAAATTCCGAAGCGGGTGGTGGTAAAACCCAAGAAGTACCGAAAACGGGAGAAGCCGCTGGTCCCACCAGTTCGCCTAAGCCGCGAAGAGATCGAGCGACGGAAGCTGCAGCAGAGCGAATACGATGACATTATCCTGCAGTTCTTCAAGAAATTTCCCTGCCACATCTGTAATCTGCTGGTGCAAAACTTTGCGGACATGCGACGCCACCAGCGCGTTTCCCACAGCATCGAGTCGGGCTACATAGAGTGCTGTGGAAAGAAGTTCCACATACGCAAGGCCTTGGCGGAGCATGTGCTGGTCCACAAGAACCCAGATCACTTCATGTGCTCGCAGTGTGGGCGGGTGTTCCAGGATTCACGCAGCCTGGAGATCCACGAGCAGACGCACACGAACCCGGAGGTTAAAACAGAGCCGAAGGAGAAGCGAGTCTACCAGTGCGAGAAGTGTCCCAAGAGCTTCACCACCAAGGCGGCCATCGAGTACCACGATGTGTCTAAGCACGTGCCCAAGTCCGAGTTTAAGTTCTCCTGCCCAGAGTGCAACAAAAAGATTCCCACGGAGCGCAAACTAAAGGAGCACCTGCGATACATGCACGACCCGGAAACGGCCATCATCTGCGATAAGTGCGGTAAGACACTGCGCTCCCAAACGAATCTCAAAAAGCACCACGAGCTGGAACATTCCGAGGAGCCGCGTCCCAAGCCCGATCCCGTCCAGTGCGAGATCTGCGGCACCTGGCTGCGCCACCTGTCCGGCCTAAAGCAGCACATGAACACGGTGCACGAGCCGCCGGGCGGCGAGCATCGGTGCCACATCTGCAACAAGACGTCCACCAACTCCAGAGCCCTCAAGCGCCACATCTACCACAACCATCTCTGCGAGCGCAAGTTCAAGTGCGGCATGTGCGAGAAAGCCTTCAAAAGGCCCCAGGACCTTAGGGAACACACGTCCACGCACACTGGGGAGGTGCTGTACACCTGCCCCAACTGCCCCATGACGTTCTTTTCCAACGCCAACATGTACAAGCACCGCCAGCGGCTGCATCGCGCCGAATGGGAGGCGGATCGCAAGAAGCCGCTGCCGCCGAACATTATGAAGATATCGCAGGGCGCCACCACGGCGATGAAGAAGCGTCAGGCCAGCGGCGCCCTGTTTCCGCAGTCGGAACAGAAGCAATAG
Protein Sequence
MATCVLCLTSSESAYGLESAEGVRLKIRATISKHFSFSEVHSAGSDASVCRECWDCVSSFEEFHQRVSRLHQERSSDSKSVPIEFCGQAEEAINPLYSVELDALAEGFFAPNEVKVEVNELEPLPKVELLEDPVNTETRTASKRLGDQNDGLHHPKRRIKNEQAVDSDSDVPLADFLSSDIKSSSNGPDKDNEPTKGRPLRRSTRRGRPPKPKPELHASPKKEPDSDEDDDDVASRENDMEFVPPEAVLGTEDSASSSSESSGEDSDHSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRLSREEIERRKLQQSEYDDIILQFFKKFPCHICNLLVQNFADMRRHQRVSHSIESGYIECCGKKFHIRKALAEHVLVHKNPDHFMCSQCGRVFQDSRSLEIHEQTHTNPEVKTEPKEKRVYQCEKCPKSFTTKAAIEYHDVSKHVPKSEFKFSCPECNKKIPTERKLKEHLRYMHDPETAIICDKCGKTLRSQTNLKKHHELEHSEEPRPKPDPVQCEICGTWLRHLSGLKQHMNTVHEPPGGEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGATTAMKKRQASGALFPQSEQKQ