Basic Information

Insect: Drosophila leontia
Gene Symbol: -
Assembly: GCA_008042735.1
Location: VNKB01000427.1:55851-58058[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0056 0.48 11.1 1.4 1 23 334 357 334 357 0.97

2 10 0.041 3.5 8.3 0.8 6 23 367 384 367 384 0.98

3 10 0.00014 0.012 16.1 0.4 1 23 390 412 390 412 0.98

4 10 6.8e-05 0.0058 17.1 0.5 2 23 428 450 427 450 0.94

5 10 0.00017 0.014 15.9 1.2 1 23 458 481 458 481 0.97

6 10 3.2e-05 0.0028 18.1 1.6 3 23 489 510 487 510 0.92

7 10 0.0011 0.09 13.3 0.4 2 23 522 544 521 544 0.97

8 10 0.00027 0.023 15.2 4.0 1 23 551 574 551 574 0.93

9 10 2.4e-06 0.0002 21.7 0.8 1 23 580 602 580 602 0.98

10 10 6.6e-05 0.0057 17.1 1.3 1 23 608 631 608 631 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0056	0.48	11.1	1.4	1	23	334	357	334	357	0.97
2	10	0.041	3.5	8.3	0.8	6	23	367	384	367	384	0.98
3	10	0.00014	0.012	16.1	0.4	1	23	390	412	390	412	0.98
4	10	6.8e-05	0.0058	17.1	0.5	2	23	428	450	427	450	0.94
5	10	0.00017	0.014	15.9	1.2	1	23	458	481	458	481	0.97
6	10	3.2e-05	0.0028	18.1	1.6	3	23	489	510	487	510	0.92
7	10	0.0011	0.09	13.3	0.4	2	23	522	544	521	544	0.97
8	10	0.00027	0.023	15.2	4.0	1	23	551	574	551	574	0.93
9	10	2.4e-06	0.0002	21.7	0.8	1	23	580	602	580	602	0.98
10	10	6.6e-05	0.0057	17.1	1.3	1	23	608	631	608	631	0.97

Sequence Information

Coding Sequence: ATGCCCCTCTGCGTGCTCTGCCTGGTTTCCTCCGATGGCGGCTACCCGCTTCTATCCGCCGAGGGCGTCCGGCTAAACATTAAGGGGACCATCAACAAACACTTTTCGTTTTTCGAGGTGATCACTGCCGGCGGTGATGGGGCGGTCTGTCGGGAGTGCTGGCAGTGCGTCAGTAGCTTCGATGAGTTCCACCAGCGGGTCTCCAGGCTGCACCAACAGCCAGGCGCCGGATGCGACTCCAAAAGCGTGGCCATCGAGTTCTGCGCCGAGACGGAAGAGGCCATCAATCCTCTGTTTGCCGTCGAACTAGATGCCCTGGCCGAGGGCTTCTTCGCCCCCAATGAAGTGAAGGTGGAGGTCAACGAGCTGGAACCTCTGCCCAAGATGGAGCTCCTCGAGGATCCAGTCAATACGGAAAGGAAACCCGCCGCCACCAAGCGACTGGGCTCCCAAGGCGAAGGTCTGTCGCAGCCCAAGCGTCgcattaaaaacgaaaaaatggTAGACAGTGATTCGGATGTGCCTCTGGCAAAGTTCATCAGCGCAGAGATTAAGGCCGGCGCCAATGGAGCAGCAAAGAACAACGAACAGGGCAAGGGACAACCGCTGCGAAGGAGCACTAGACGTGGTCGGCCACCAAAGGTCAAACCCGAGGATCTTGCGTCTCCCAAAAAGGAACTCGAgtcggatgatgatgatgaccacGGGGTTAATGACAACGACAGGGAATTCGTGGCCGCAGAAGCCGTCTTGGGCACTGACGACAGCTCGAGTTCCTCCAGCGAAAGCAGTGACGGTGACTCGGACGACAGCTTGCCGGACTTTGAGCCGGTGGAGCGGTACGCCGAGATCCCCAAGCGCGTTGTTGTGAAGCCCAAAAAGTACCGGAAACGCGAGAAACCATTGATCCCACCCAACCGCATGAGTCGCGAGGAGATCGAGCAACGAAAGCAGCGGCAGGACGAGTACGATGATATTATCCTGCAGTTCTTCAAGAAGTTCCCCTGCCACATCTGTAACCTTCTCGTTCAGAACTTTTCGGACATGCGACGCCATCAGCGGGTTTCCCACGACATGGAATCGGGTTACATGCAGTGCTGCGGGAGAAAGTTCCACACACGCAAGAGTCTGGCGGAGCATGTGTTGGTCCATAAGAATCCGGAGCACTTTATGTGCTCGCAATGCAGCCGGGTCTTCCAGGATTCCCGTGCCCTGGAGGTCCACGAGCAGACGCACGTGAATCCGGACGTGAAGCCAGAGCCCAAGGAGAAGCGGATGTGGCCGTGTGAGAAGTGCTCCAAGAGTTTTACCAGCAAGGCGGCCCTCGAGTATCACTTTATGTCCAAGCACGTGCCCAAGTCCGAGTTCAAATACAGTTGTACAGAGTGTAACAAGAAGATTCCCACGGAGCGCAAGCTGAGGGAGCACATGCGCTATATGCACGATCCGGAAACGGCCATCATTTGCGACAAATGCGGCAAGACGTTGCGTTCCCAAACGAATCTCAAGAAGCATCACGAACTGGAACATTCCGAGGAGCCACGTCCGAAACCCGATCCTGTGCAGTGCGAGATCTGCGGCACCTGGTTGCGTCACCTGTCCGGGCTGAAGCAGCATATGAACACTGTGCACGAGCCGCAGGGCAAAGAGCACCGCTGTCCCATATGCAACAAGCAGTCCACCAACTCCAGAGCCCTCAAGCGTCACATTTACCACAACCATCAGTGTGAGCGCAAGTTCAAGTGTGGGATGTGCGAGAAGGCCTTCAAGCGGCCGCAGGATCTAAGAGAACACACGTCCACGCACACCGGCGAGGTGCTCTACACCTGCCCCAACTGTCCCATGACATTCTTTTCCAATGCCAACATGTACAAGCATCGCCAGCGACTCCATCGCGCCGAATGGGAGGCGGACCGAAAGAAGCCGCTGCCGCCGAACATCATGAAGATATCGCAGGGCGCCACCACGGCGATGAAAAAACGACAGTCCAGCAGCACTCTATTCCCACAGTTGGAACAGAAGCAATAG
Protein Sequence: MPLCVLCLVSSDGGYPLLSAEGVRLNIKGTINKHFSFFEVITAGGDGAVCRECWQCVSSFDEFHQRVSRLHQQPGAGCDSKSVAIEFCAETEEAINPLFAVELDALAEGFFAPNEVKVEVNELEPLPKMELLEDPVNTERKPAATKRLGSQGEGLSQPKRRIKNEKMVDSDSDVPLAKFISAEIKAGANGAAKNNEQGKGQPLRRSTRRGRPPKVKPEDLASPKKELESDDDDDHGVNDNDREFVAAEAVLGTDDSSSSSSESSDGDSDDSLPDFEPVERYAEIPKRVVVKPKKYRKREKPLIPPNRMSREEIEQRKQRQDEYDDIILQFFKKFPCHICNLLVQNFSDMRRHQRVSHDMESGYMQCCGRKFHTRKSLAEHVLVHKNPEHFMCSQCSRVFQDSRALEVHEQTHVNPDVKPEPKEKRMWPCEKCSKSFTSKAALEYHFMSKHVPKSEFKYSCTECNKKIPTERKLREHMRYMHDPETAIICDKCGKTLRSQTNLKKHHELEHSEEPRPKPDPVQCEICGTWLRHLSGLKQHMNTVHEPQGKEHRCPICNKQSTNSRALKRHIYHNHQCERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGATTAMKKRQSSSTLFPQLEQKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507782;
90% Identity: iTF_00561917;
80% Identity: -