Basic Information

Insect: Drosophila biarmipes
Gene Symbol: ZNF574
Assembly: GCA_018148935.1
Location: JAECYG010000260.1:2772809-2776234[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.049 2.9 8.3 0.3 1 23 332 355 332 355 0.96

2 10 0.58 35 4.9 0.4 6 23 365 382 365 382 0.98

3 10 0.00011 0.0063 16.7 0.2 1 23 388 410 388 410 0.98

4 10 0.00036 0.022 15.0 0.9 1 23 425 448 425 448 0.89

5 10 0.11 6.5 7.2 0.1 4 23 459 479 459 479 0.95

6 10 2.8e-05 0.0017 18.5 1.4 3 23 487 508 485 508 0.92

7 10 0.0012 0.071 13.4 0.4 2 23 520 542 519 542 0.97

8 10 0.00061 0.036 14.3 7.1 1 23 549 572 549 572 0.93

9 10 2.7e-06 0.00016 21.7 0.8 1 23 578 600 578 600 0.98

10 10 7.5e-05 0.0045 17.1 1.3 1 23 606 629 606 629 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.049	2.9	8.3	0.3	1	23	332	355	332	355	0.96
2	10	0.58	35	4.9	0.4	6	23	365	382	365	382	0.98
3	10	0.00011	0.0063	16.7	0.2	1	23	388	410	388	410	0.98
4	10	0.00036	0.022	15.0	0.9	1	23	425	448	425	448	0.89
5	10	0.11	6.5	7.2	0.1	4	23	459	479	459	479	0.95
6	10	2.8e-05	0.0017	18.5	1.4	3	23	487	508	485	508	0.92
7	10	0.0012	0.071	13.4	0.4	2	23	520	542	519	542	0.97
8	10	0.00061	0.036	14.3	7.1	1	23	549	572	549	572	0.93
9	10	2.7e-06	0.00016	21.7	0.8	1	23	578	600	578	600	0.98
10	10	7.5e-05	0.0045	17.1	1.3	1	23	606	629	606	629	0.97

Sequence Information

Coding Sequence: ATGACTGCCTGCGTGCTCTGCCTGGTCTCCTCCGATGCCGGCATCGGCCTGCAGTCCGCGGAGGGCGTGCGTCTGGGCATTAGGGCGACCATCAACAAGCACTTTTCGTTCTCCGAGGTCCTTACTGCGGGCAGTGATGCGGCGGTCTGCCGGGAGTGCTGGGACTGCATCAGCAGCTTCGAGGAGTTCCACCAGCGGGTCTCCGGCCTGCACCAGCAGCGCATCAGCGACGCCAAGAGCGTGCCCATCGAGTTCTTCGGCCAGACGGAGGAGCCCATCAATCCGCTGTACTCCGTGGAGCTCGACGCCCTGGCCGAGGGGTTCTTTGCGCCCAGCGAGGTGAAGGTCGAGGTGAACGAGCTGGAGCCGCTGCCCAAGGTGGAACTCCTGGAGGACCCGGTCAACACGGAAAGCAGAACTGCTTCCAAGCGGCTAGGTGGCCATAGCGAGGGCTCCCCGCACCCAAAGCGGCGCATTAAGAACGAACAGCCACTGGACAGTGACTCGGATGTACCTTTAGCCGATTTTCTGGGCTCGGACAGCAAGAGCAGCTCTAGTAAACCGGCAAAGAACAGCCAGCCGACCAAGGGCCGCCCGCTGCGTAGGAGCACGAGACGTGGGCGACCGCCCAAGGCCAAGCCAGAGCCCGCTGCTTCGCCGAAGAAGGAGGAACTGGACTCCAACGACGAGGAGGACAACGCCAGAGAAAGCAATGACATGGAGTTTGTGCCTGCCGAGGCGGTCCTGGGCACAGACGACAGTGGCAGCTCCTCCAGCGACAGCAGTGGCGAGGACTCCGACCAGAGCCTGCCCGACATTGAGCCCGAGGAGCGGTACGCCGAGATTCCCAAGCGGGTGGTGGTGAAGCCCAAGAAGTACCGAAAGCGGGAGAAGCCCCTGGTGCCGCCGGTTCGCCTGAGCCGGGAGGAGATCGAGCGACGGAAGCTCCAGCAGAGCGAGTACGACGAGATTATCCTGCAGTTCTTCAAGAAGTTTCCCTGCACCATCTGCAATCTGCTGGTGCAGAACTTTGCGGACATGCGACGCCATCAGCGGCTTTCCCACAACATCGAGGCTGGCTACATGGAGTGCTGCGGGAAGAAGTTCCACATCCGCAAGACCCTGGCGGAGCATGTACTGGTCCACAAGAACCCGGAGCACTTTATGTGCTCTCAGTGCGGGCGGGTGTTCCAGGACTCGCGCGCCCTGGATGTGCACGAGCAGACGCACACGAATCCGGAGGTCAAGGCGGAGCCAAAGGAAAAGCCGGTCTACCAGTGCGAGAAGTGCCCCAAGAGCTTCATCACCAAGTCGGCCATAGACTACCACTACGTGTCCAAGCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCAGAGTGCAACAAGAAGATCCCCACGGAGCGCAAGCTGAAGGAGCACCTGCGCTACATGCACGACCCGGAATCAGCCATCATCTGCGATAAGTGCGGCAAGACGGTTCGCTCGCAAACGAATCTCAAGAAGCACCACGAGCTGGAACATTCCGAGCAGCCGCGTCCCAAGCCGGATCCCGTGCAGTGCGAGATATGCGGCACCTGGCTGCGCCACCTCTCAGGACTGAAGCAGCACATGAACACGGTGCACGAGCCGCCGGGCGGCGAGCATCGCTGTCACATCTGCAACAAGACATCCACCAACTCCAGGGCCCTCAAGCGCCACATCTACCACAACCATCTGTGCGAGCGCAAGTTCAAGTGCGGGATGTGCGAGAAGGCCTTCAAGCGACCACAAGACCTTAGGGAACACACATCCACCCACACCGGCGAGGTCCTCTACACTTGCCCCAATTGCCCCATGACGTTCTTCTCCAACGCCAACATGTACAAGCACCGGCAGCGACTCCATCGAGCAGAGTGGGAGGCGGACCGCAAGAAGCCGCTGCCACCGAACATCATGAAGATTTCGCAGGGCGCCACCTCGGCCATGAAGAAGCGCCAGGGCGGCGGCGCCCTGTTCCCACAGTCGGAACAGAAGCAATAG
Protein Sequence: MTACVLCLVSSDAGIGLQSAEGVRLGIRATINKHFSFSEVLTAGSDAAVCRECWDCISSFEEFHQRVSGLHQQRISDAKSVPIEFFGQTEEPINPLYSVELDALAEGFFAPSEVKVEVNELEPLPKVELLEDPVNTESRTASKRLGGHSEGSPHPKRRIKNEQPLDSDSDVPLADFLGSDSKSSSSKPAKNSQPTKGRPLRRSTRRGRPPKAKPEPAASPKKEELDSNDEEDNARESNDMEFVPAEAVLGTDDSGSSSSDSSGEDSDQSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRLSREEIERRKLQQSEYDEIILQFFKKFPCTICNLLVQNFADMRRHQRLSHNIEAGYMECCGKKFHIRKTLAEHVLVHKNPEHFMCSQCGRVFQDSRALDVHEQTHTNPEVKAEPKEKPVYQCEKCPKSFITKSAIDYHYVSKHXXXXXXXXXXPECNKKIPTERKLKEHLRYMHDPESAIICDKCGKTVRSQTNLKKHHELEHSEQPRPKPDPVQCEICGTWLRHLSGLKQHMNTVHEPPGGEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGATSAMKKRQGGGALFPQSEQKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507782;
90% Identity: iTF_00602791; iTF_00605019;
80% Identity: -