Basic Information

Insect: Drosophila truncata
Gene Symbol: ZNF574
Assembly: GCA_008042515.1
Location: VNJQ01008019.1:16333-18551[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.04 3.5 8.3 0.8 1 23 336 359 336 359 0.96

2 10 0.083 7.3 7.3 0.4 6 23 369 386 369 386 0.98

3 10 9.4e-05 0.0082 16.6 2.0 1 23 392 414 392 414 0.98

4 10 0.00051 0.045 14.3 1.4 1 23 429 452 429 452 0.96

5 10 8.4e-05 0.0073 16.8 0.6 1 23 460 483 460 483 0.97

6 10 0.00043 0.038 14.5 2.2 3 23 491 512 489 512 0.92

7 10 0.001 0.09 13.3 0.4 2 23 524 546 523 546 0.97

8 10 6.2e-05 0.0054 17.2 4.1 1 23 553 576 553 576 0.93

9 10 2.3e-06 0.0002 21.7 0.8 1 23 582 604 582 604 0.98

10 10 6.5e-05 0.0057 17.1 1.3 1 23 610 633 610 633 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.04	3.5	8.3	0.8	1	23	336	359	336	359	0.96
2	10	0.083	7.3	7.3	0.4	6	23	369	386	369	386	0.98
3	10	9.4e-05	0.0082	16.6	2.0	1	23	392	414	392	414	0.98
4	10	0.00051	0.045	14.3	1.4	1	23	429	452	429	452	0.96
5	10	8.4e-05	0.0073	16.8	0.6	1	23	460	483	460	483	0.97
6	10	0.00043	0.038	14.5	2.2	3	23	491	512	489	512	0.92
7	10	0.001	0.09	13.3	0.4	2	23	524	546	523	546	0.97
8	10	6.2e-05	0.0054	17.2	4.1	1	23	553	576	553	576	0.93
9	10	2.3e-06	0.0002	21.7	0.8	1	23	582	604	582	604	0.98
10	10	6.5e-05	0.0057	17.1	1.3	1	23	610	633	610	633	0.97

Sequence Information

Coding Sequence: ATGTCCGTCTGCGTGCTCTGCTTGGTTTGCTCCGATGGCGGCTACCCCCTGTTGTCCGCCGAGGGCGTCCGGCTGAACATTAAGGGAATCATCAACAaacatttttcgtttttcgagGTGCTCACTGCTGGCAGTGATGCCGCGGTCTGCCGCGAATGCTGGCAGTGCGTCAGCAGCTTCGATGAGTTCCACCAGCGAGTCTCCAGGCTGCACGAACAGCCACTTAGAGGCGACGCCAAAAGCGTGGCCATTGAGTTCTGCGCCGAAACGGAAGAGGCCATCAATCCTCTATTTGCCGTGGAACTGGATGCCCTGGCCGAGGGCTTCTTCGCCCCCAATGAAGTGAAGGTGGAGGTCAATGAGCTCGAACCTTTGCCCAAGGTGGAGCTCCTCGAGGACCCAGTGAAAACCGAAAGGAGAACTGGTGCCACCAAGCGACTGGGTGCCCAATCCGAAGGTCAATCCCAGCCCAAGCGTCgcattaaaaacgaaaaaattgtGGACAGTGACTCGGATGTGCCGCTGGCGAAATTCGTGGGCACAGAGATGAAGACCGGCTCCAACGGACCGGCAAAAAACAACGAACAAGGCAAGGGACAGCCACTGCGAAGGAGCACGAGACGTGGTCGCCCACCAAAGGTCAAGCCAGAGGATCTGGCGTCTCCCAAAAAAGAACTCGAATCGGATGATGAAGAACACGACAACAGAAATGACAATGACGGGGAATTCGTGCCCGCTGAAGCCGTTTTGGGTACGGATGACAGCGCAAGTTCGTCCAGCGAAAGCAGTGATGATGCTGATAATGATTCGGATAACAGCCTGCCGGACTTTGAGCCCGAGGAACGGTATGCCGAGATCCCTAAGCGGGTCGTTGTGAAGCCCAAAAAGTACCGAAAACGAGAAAAACCTTTGGTCCCGCCCGTCCGCATGAGTCGCGAGGAGATCGAGCGAcgaaaacagcagcaggacgAGTACGATGAGCTTATCCTAGAGTTCTTCAAGAAGTTCCCCTGCCACATCTGCAACCTACTCGTGCAGAATTTTGCAGACATGCGATCCCATATGCGCCTCACCCACAACATCGAATCGGGCTTCATGCAGTGCTGCGGCCGAAAGTTTCACACGCGCAAGGGTCTGGCGGAGCATGTGTTGGTCCACAAGAATCCGGAACACTTTATGTGCTCGCACTGCAGCCGTGTCTTCCAGGACTCGCGCTCGCTGGAGATTCACGAGCAGACGCACACCAATCCGGATGTGAAGACAGAGCCAAAGGAGAAGCGTATGTTTCCGTGCGAAAAGTGTTCCAAGACATTTACCAGCAAGGCGGCCACAGAATATCATTATATGTCCAAGCATGTACCCAAGTCCGAGTTCAAATTCACCTGTCCAGAGTGTAACAAGAAgATACCCACGGCGCGCAAGCTAAAGGAGCATCTACGCTACATGCACGACCCCGAAACGGCCATCATTTGCGACAAGTGCGGCAAGACAGTGCGGTCCCATGGGTATCTCAAGAAGCACCATGAACTGGAACATTCCGAAGAGCCACGTCCAAAGCCCGATCCCGTACAATGTGAGATTTGCGGCACCTGGTTGCGTCACCTGTCTGGCCTGAAGCAGCACATGAACACGGTGCATGAGCCGCCGGGCAGCGAGCACCGCTGTCCCATATGCAACAAGACGTCCACCAATTCCAGAGCCCTCAAGCGTCACATTTACCACAATCATCAGTGTGAGCGCAAGTTCAAGTGCGGAATGTGTGAAAAGGCCTTTAAACGGCCGCAGGATTTGAGAGAACACACTTCCACGCACACCGGCGAGGTGCTTTACACCTGTCCCAATTGTCCCATGACGTTCTTTTCCAACGCCAACATGTACAAGCATCGCCAGCGGCTCCATCGCGCCGAATGGGAGGCGGACCGAAAGAAACCGCTGCCGCCGAACATCATGAAGATGTCGCAGGGCGTCACCACGGCCATGAAGAAGCGGCAGACCAGCAGCAACCTGTTCCCACAGTCACAGGAACAGAAGCAATAG
Protein Sequence: MSVCVLCLVCSDGGYPLLSAEGVRLNIKGIINKHFSFFEVLTAGSDAAVCRECWQCVSSFDEFHQRVSRLHEQPLRGDAKSVAIEFCAETEEAINPLFAVELDALAEGFFAPNEVKVEVNELEPLPKVELLEDPVKTERRTGATKRLGAQSEGQSQPKRRIKNEKIVDSDSDVPLAKFVGTEMKTGSNGPAKNNEQGKGQPLRRSTRRGRPPKVKPEDLASPKKELESDDEEHDNRNDNDGEFVPAEAVLGTDDSASSSSESSDDADNDSDNSLPDFEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRMSREEIERRKQQQDEYDELILEFFKKFPCHICNLLVQNFADMRSHMRLTHNIESGFMQCCGRKFHTRKGLAEHVLVHKNPEHFMCSHCSRVFQDSRSLEIHEQTHTNPDVKTEPKEKRMFPCEKCSKTFTSKAATEYHYMSKHVPKSEFKFTCPECNKKIPTARKLKEHLRYMHDPETAIICDKCGKTVRSHGYLKKHHELEHSEEPRPKPDPVQCEICGTWLRHLSGLKQHMNTVHEPPGSEHRCPICNKTSTNSRALKRHIYHNHQCERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKMSQGVTTAMKKRQTSSNLFPQSQEQKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507782;
90% Identity: iTF_00561917;
80% Identity: -