Dfal007586.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila falleni
Gene Symbol
-
Assembly
GCA_035045575.1
Location
JAWNOV010000062.1:21331954-21335076[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00024 0.018 15.6 0.7 1 23 203 226 203 226 0.97
2 12 4.8e-06 0.00036 21.0 3.6 1 23 231 254 231 254 0.96
3 12 0.00042 0.032 14.8 4.5 1 23 259 281 259 281 0.98
4 12 5.3 4e+02 1.9 5.7 2 23 288 311 287 311 0.90
5 12 0.00047 0.035 14.7 1.0 3 23 321 342 320 342 0.95
6 12 0.0022 0.17 12.6 0.1 1 23 348 371 348 371 0.95
7 12 0.3 22 5.9 0.2 5 23 387 406 382 406 0.87
8 12 3.9e-05 0.0029 18.1 0.3 1 23 434 456 434 456 0.98
9 12 1.4e-05 0.001 19.5 5.4 1 23 462 484 462 484 0.96
10 12 4.2e-05 0.0031 18.0 0.4 2 23 491 512 491 512 0.97
11 12 0.0012 0.09 13.4 1.0 1 23 519 541 519 541 0.99
12 12 3.1e-05 0.0023 18.4 2.7 1 23 547 570 547 570 0.98

Sequence Information

Coding Sequence
ATGGAAACGTGTCGCACTTGTGCAAAGTGCGATTTcgaaaatggcaacaacaactattggCTGGACTTGTTCCATCCAACCCATTGGCAGAGTGAAATGGCCCAAATTCGCATGGAGTTTGTTAACTGGAAGTTACAGATCTCACCTAACGATGGACTGCCACAGAAAATATGCAGCGATTGCTTTACGAAATTCTGCTCCATTTACACGTTTCGAATGGCTTGCCAGGATGCACAATTAAAGCTGTCGaatatatttgataaaatCGATGCCAACATAATGTATGACAAGACAGAAGATGACCAagttaatgatgatgatgatgatgataagaAAACAGAAGCgataacagaaacaacaacaacacaaaacacTGCCAATTTTGAGGCCAAATCGCCAACGCCCATAGAAATCTATGTAGAAACGATAAACATCAACGAAACACAAACACTGCAATTAGATAAGGAAGAGGAAGATTTTTCTACAGATTTTAACTCCTTAAACATCAGCTATGCTTGTAAATTTTGCTACAAGCCCCAAGAGAGCTATGAACTGCAGCATATGCTTTTAGAGCACATCAGTAGCGCCCATGATCCGGATCAGCCCTATAACTGTCCGGAATGCCCGGAATGTTTCCAAGATGCCGCATCACGTACCGTGCATATGAAGAACTTCCATGTCGTTAAGCATTACGTCTGCGAGGTTTGCGGCAAAAAGTACAGCGATCGTCATAATCTACGACATCATGTTGAGAAATATCACTCGGAAACGGATTTCGAATGCAGCCTGTGTGAGAAGCGTTTCTTTACCCGCAAAAGTTTACACTACCACATGAATTGGCACAAACCGGAGCGTCAGTTGAGATGTAGACACAGCGGTTGCGACAGATTGTTCATCAATCAACGACATCTCAAGTGTCACGAAGCGACTCACACCACGGGATCCCGAAAGAGTGAATACTGTGGTTTTTGTGGCAaagCTTTCATTCATGTTAAAACCTTACGATGGCATATCTATCGACAACATGGCGGAGAGAAACCTTTTAAATGTGCCATTTGCACTGAGGTTTTTGCATCGTATGCTGAGAAACGAATCCATATGCTTGAGTTGCATACAGAAAATCTCACACATCAGGAACGTAGCGAGTGCATGTTCCAGTCCTGCCGCCAGGAGTTTGATAACGAACAGGACCTCATCCAGCACATGAGCGCTGAACATCTACGCGAACCAGCAACTCCAATCATTGCCAACAATAAGCGCGTCCTCCAACGGAAGACGGAGCGACAATATACAGGACTTTTCCAGTGCGATAGTTGCCCCCAACGCTTTAATATGAAGTCAGCCCTGGATCGTCACATGGCAGTGCATTCGACTGATCGATTACACGCCTGCACACACTGTTCCAAGCGTTATAAGCGTGCCCAGGACTTGAAGTGGCATATGAAGACACATGCCAATGAGAAACCCAATGTTTGTGATGTTTGTGGCAAATCATTTGCCCTGAAATATGTGCTTACGCAGCATAAGCGAAGTCATGAGGTTCTTGAGAAGAACTTTAAGTGTGATACTTGTGGGCGTGCCTATCTATTTGAGAAGTCGCTTCGTCTACATCAACGTGTTCACACAGGCAATACTTACTACAAATGCGATGTGTGTCAGGAACGATTTGTGACTCACATCAagcttaaaaCTCACATGAAGAAGGCACACGATACAAACCAGTCCAATACTAAGGATGCGCTGGATGATTTGATCAACATTGTGATTTCCTAA
Protein Sequence
METCRTCAKCDFENGNNNYWLDLFHPTHWQSEMAQIRMEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANIMYDKTEDDQVNDDDDDDKKTEAITETTTTQNTANFEAKSPTPIEIYVETININETQTLQLDKEEEDFSTDFNSLNISYACKFCYKPQESYELQHMLLEHISSAHDPDQPYNCPECPECFQDAASRTVHMKNFHVVKHYVCEVCGKKYSDRHNLRHHVEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDNEQDLIQHMSAEHLREPATPIIANNKRVLQRKTERQYTGLFQCDSCPQRFNMKSALDRHMAVHSTDRLHACTHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKSFALKYVLTQHKRSHEVLEKNFKCDTCGRAYLFEKSLRLHQRVHTGNTYYKCDVCQERFVTHIKLKTHMKKAHDTNQSNTKDALDDLINIVIS