Dneo015982.1
Basic Information
- Insect
- Drosophila neotestacea
- Gene Symbol
- -
- Assembly
- GCA_035044365.1
- Location
- JAWNMD010000672.1:22006-25848[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0023 0.17 12.6 1.7 1 23 202 225 202 225 0.96 2 12 5e-05 0.0038 17.8 2.7 1 23 230 253 230 253 0.95 3 12 0.00043 0.033 14.8 4.5 1 23 258 280 258 280 0.98 4 12 4.7 3.6e+02 2.1 5.8 2 23 287 310 286 310 0.91 5 12 0.00047 0.036 14.7 1.0 3 23 320 341 319 341 0.95 6 12 0.0023 0.18 12.5 0.1 1 23 347 370 347 370 0.95 7 12 0.15 12 6.8 0.2 5 23 386 405 381 405 0.89 8 12 7.5e-05 0.0057 17.2 0.2 1 23 434 456 434 456 0.98 9 12 1.4e-05 0.0011 19.5 5.4 1 23 462 484 462 484 0.96 10 12 8.7e-06 0.00067 20.2 0.1 2 23 491 512 491 512 0.97 11 12 0.0012 0.093 13.4 1.0 1 23 519 541 519 541 0.99 12 12 0.0004 0.031 14.9 4.1 1 23 547 570 547 570 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACTTGTGCGAAGTGCGATTTcgaaaatggcaacaacaactattggCTTGACTTGTTTCATCCAAACCGTTGGCAGAGTGAAATGGCGCAAATTCGCATGGAGTTTGTTAACTGGAAGTTACAGATCTCACCCAACGATGGACTGCCACAGAAAATATGTAGCGATTGTTTTACGAAATTTTGCTCCATTTACACATTTCGCATGGCCTGCCAGGATGCACAATTAAAACTGTcgaatatttttgataaaatcGATGCCAATATACTATACGACAAAACTAAAGAAGACCAATTTGATGATGAAGTGGGTGAAGTTGAGGAAACAGAAGCGATAACAGAAACTACATCAACACAACACACTGCCATAATTGAGGCCAATTCGTTAACGCCCTTAGAAATCTATGTAGATACGTTAAACATCAGCGAGACAGAAACATTGCAATTAGGTGAGGATGGAGATTTTTCTACAGACTTCAACTCCTTAAACATTAGCTACGCTTGCAAATTTTGCTACAAGCCACAAGAGAGCTACGAACTACAACATATGCTTTTAGAACACATCAGTAGCGCCCATGATCCAGACCAGCCATATAATTGTCCGGAATGCACGGAATGTTTCCAAGATACCGCATCCCGCACGGTGCATATGAAGAATTCTCACGTTGTTAAGCACTACGCCTGCGAAGTGTGTGGTAAGAAGTACGGAGATCGTCATAATCTACGACATCATGTTGAGAAATATCACTCGGAAACGGATTTCGAATGCAGCCTGTGCGAGAAGCGCTTCTTTACCCGCAAAAGCCTGCACTACCACATGAATTGGCATAAGCCGGAGCGTCAATTGAAATGTAGACACAGCGGTTGCGACCGATTGTTTATCAATCAACGACATCTCAAATGTCATGAAGCAACTCATACAACGAGCTCTCGAAAGAGTGAATACTGTGGTTTTTGCGGCAAAGCTTTCATACATGTAAAAACCTTACGTTGGCACATCTATCGACAACATGGCGGTGAAAAGCCTTTTAAATGTGCCATCTGCACTGAGGTTTTTGCATCGTATGCTGAAAAACGCATCCATATGCTTGAGTCTCATACGGAAAATCTGACTCATCAGGAACGTAGCGAGTGTATGTTCCAGTCCTGCCGCCAGGAGTTTGATAACGAACAGGACCTCATCCAGCACATGGGTACCGAACATTTACAGCGCGAACCAGCAGCTCCAATCATTGCCAACAATAAGCGCGTCCTACAACGGAAGCGGGAGCGACAATATACGGGTCTTTTCCAGTGCGGCAGTTGCCCCCAACGCTTCAATATGAAATCAGCCCTGGATCGCCATATGGCTGTGCACTCGACAGATCGTTTGCACGCCTGTACGCACTGCTCCAAGCGCTATAAGCGTGCCCAGGACTTAAAGTGGCATATGAAGACACATGCCAACGAGAAACCCAATGTTTGTGATGTTTGCGGAAAAGCATTTGCCCTAAAATATGTTCTTACTCAGCATATGCGTAGTCATGAGGTTCTTGAGAAGAACTTTAAGTGTGACACTTGTGGACGTGCCTACCTATTTGAGAAGTCCCTTCGTCTGCATCAACGCGTCCACACAGGCAATACTTACTACAAATGCGATTTGTGCCAGGAACGATTTGTGACTCACATCAAGTTCAAAACTCACATGAAGAAAGTACACGATAAAAACCAGTCCCATATTAAGGACTCGCTGGATGATTTGATCAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCAKCDFENGNNNYWLDLFHPNRWQSEMAQIRMEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANILYDKTKEDQFDDEVGEVEETEAITETTSTQHTAIIEANSLTPLEIYVDTLNISETETLQLGEDGDFSTDFNSLNISYACKFCYKPQESYELQHMLLEHISSAHDPDQPYNCPECTECFQDTASRTVHMKNSHVVKHYACEVCGKKYGDRHNLRHHVEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLKCRHSGCDRLFINQRHLKCHEATHTTSSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYAEKRIHMLESHTENLTHQERSECMFQSCRQEFDNEQDLIQHMGTEHLQREPAAPIIANNKRVLQRKRERQYTGLFQCGSCPQRFNMKSALDRHMAVHSTDRLHACTHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCDTCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKVHDKNQSHIKDSLDDLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00507070;
- 80% Identity
- -