Basic Information

Insect: Drosophila macrospina
Gene Symbol: -
Assembly: GCA_035042075.1
Location: JAWNLW010000470.1:3357-6512[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8.8 5.7e+02 1.2 1.8 3 16 58 71 57 73 0.84

2 14 2.9 1.9e+02 2.8 0.7 1 23 168 194 168 194 0.85

3 14 0.00033 0.022 15.1 0.2 1 23 200 223 200 223 0.97

4 14 4.9e-05 0.0032 17.8 2.7 1 23 228 251 228 251 0.95

5 14 0.00041 0.027 14.9 4.5 1 23 256 278 256 278 0.98

6 14 5.2 3.4e+02 1.9 5.7 2 23 285 308 284 308 0.90

7 14 0.00046 0.03 14.7 1.0 3 23 318 339 317 339 0.95

8 14 0.0022 0.14 12.6 0.1 1 23 345 368 345 368 0.95

9 14 0.67 44 4.7 0.1 5 23 384 403 379 403 0.84

10 14 1.3e-05 0.00083 19.6 0.2 1 23 432 454 432 454 0.98

11 14 1.3e-05 0.00087 19.5 5.4 1 23 460 482 460 482 0.96

12 14 8.5e-06 0.00055 20.2 0.1 2 23 489 510 489 510 0.97

13 14 0.0012 0.077 13.4 1.0 1 23 517 539 517 539 0.99

14 14 0.00034 0.022 15.1 3.9 1 23 545 568 545 568 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8.8	5.7e+02	1.2	1.8	3	16	58	71	57	73	0.84
2	14	2.9	1.9e+02	2.8	0.7	1	23	168	194	168	194	0.85
3	14	0.00033	0.022	15.1	0.2	1	23	200	223	200	223	0.97
4	14	4.9e-05	0.0032	17.8	2.7	1	23	228	251	228	251	0.95
5	14	0.00041	0.027	14.9	4.5	1	23	256	278	256	278	0.98
6	14	5.2	3.4e+02	1.9	5.7	2	23	285	308	284	308	0.90
7	14	0.00046	0.03	14.7	1.0	3	23	318	339	317	339	0.95
8	14	0.0022	0.14	12.6	0.1	1	23	345	368	345	368	0.95
9	14	0.67	44	4.7	0.1	5	23	384	403	379	403	0.84
10	14	1.3e-05	0.00083	19.6	0.2	1	23	432	454	432	454	0.98
11	14	1.3e-05	0.00087	19.5	5.4	1	23	460	482	460	482	0.96
12	14	8.5e-06	0.00055	20.2	0.1	2	23	489	510	489	510	0.97
13	14	0.0012	0.077	13.4	1.0	1	23	517	539	517	539	0.99
14	14	0.00034	0.022	15.1	3.9	1	23	545	568	545	568	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAAGTGCGATTTcgaaaatggcaacaacaactattggCTGGACTTGTTCCATCCAACCCGTTGGCAGAGTGAAATGGCGCAAATTCGCATGGAATTTGTTAACTGGAAATTACAGATCTCACCCAACGATGGACTGCCACAGAAAATATGCAGCGATTGTTTTACAAAATTCTGCTCCATTTACACATTTCGCATTGCCTGCCAGGATGCGCAATTAAAGCTGTCgaatatttttgataaaatCGATGCCAACCTACTGTATGACAAAACTGAAGATGACCAAGTTGATGCTGGCACTGATGTGAAAACTGAGAGCACAGaagcaataactacaacaCAAAACACTGCCATAATTGAGGCCAAATCACAAACGCCCATAGAAATCTATGTAGAAGCAATAAACATTAACGAGACAGAGACATTGGAATTCGATAAAGTTGAAGATTTTTCTACAGATTTCAATTCCTTAAACATCAGCTATGCTTGTAAATTTTGCTATAAGCCACAAGAAAGCTTTGAGCTTCAGCATATGCTTTTGGAACACATCAGCAGCGCCCATGATTCTGACCAGCCATATAACTGTCCTGAATGCACGGAAAGTTTCCAAGATGCCGCATCCCGAACTGTGCATATGAAAAACTCCCATGTTGTGAAGCACTACGCATGCGAGGTGTGCGGCAAAAAGTATGGAGATCGACATAACCTTCGACATCACGTTGAGAAATATCACTCCGAAACGGATTTCGAGTGCAGCCTGTGCGAAAAACGATTCTTTACCCGCAAAAGTTTGCATTACCACATGAACTGGCACAAACCAGAGCGCCAGTTGAGATGTAGACACAGTGGTTGCGACAGACTGTTCATTAATCAACGACATCTCAAATGTCATGAGGCAACTCATACAACGGGATCCCGAAAGAGTGAATACTGCGGTTTTTGTGGCAAAGCTTTCATTCATGTTAAAACCTTACGGTGGCATATTTATCGTCAACATGGCGGAGAGAAGCCTTTTAAATGTGCCATCTGCACTGAAGTTTTTGCATCGTATGCTGAGAAACGCATCCATATGCTTGAGTTGCATACGGAAAATCTAACACAACAGGAACGTAGCGAGTGCATGTTTCAGTCCTGTCGCCAGGAGTTTGAGAACGAACAGGATCTCATTCAGCACATGGGTGCGGAGCATCTCCAGCGCGAACCAGCAGCTCCAATAATTGCCAACAATAAACGCGTCCTCCAACGGAAGCGGGAGCGTCAATATACGGGCCTTTTCCAGTGCGGCAGCTGTCCTCAACGCTTCAATATGAAGTCAGCCTTGGAACGTCATATGGCAGTGCATTCCACAGATCGATTGCATGCCTGTACCCACTGTTCCAAGCGATATAAGCGTGCCCAGGACTTAAAGTGGCATATGAAGACGCATGCCAACGAGAAGCCCAATGTTTGTGATGTCTGTGGTAAAGCATTTGCCCTGAAATATGTGCTAACCCAGCATATGCGTAGTCATGAAGTTCTTGAGAAGAACTTCAAATGCGACACCTGCGGACGTGCCTATCTATTTGAGAAGTCTCTTCGCTTACATCAACGGGTTCACACGGGCAACACTTACTACAAATGCGATTTGTGTCAGGAGCGATTTGTGACTCACATCAagtttaaaaCTCACATGAAGAAGGCACACGATACAAACGAGTCCCATTCTAAGGATTCGCTAGATGATTTGATCAACATTGTGATTTCATAA
Protein Sequence: METCRTCAKCDFENGNNNYWLDLFHPTRWQSEMAQIRMEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRIACQDAQLKLSNIFDKIDANLLYDKTEDDQVDAGTDVKTESTEAITTTQNTAIIEAKSQTPIEIYVEAININETETLEFDKVEDFSTDFNSLNISYACKFCYKPQESFELQHMLLEHISSAHDSDQPYNCPECTESFQDAASRTVHMKNSHVVKHYACEVCGKKYGDRHNLRHHVEKYHSETDFECSLCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYAEKRIHMLELHTENLTQQERSECMFQSCRQEFENEQDLIQHMGAEHLQREPAAPIIANNKRVLQRKRERQYTGLFQCGSCPQRFNMKSALERHMAVHSTDRLHACTHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCDTCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKAHDTNESHSKDSLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00507070;
80% Identity: -