Basic Information

Insect: Drosophila neonasuta
Gene Symbol: -
Assembly: GCA_005889595.1
Location: MRUE01001587.1:9163-12382[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 9.3 9.3e+02 1.0 1.9 3 16 58 71 57 73 0.84

2 13 0.00028 0.028 15.2 1.0 1 23 215 238 215 238 0.97

3 13 6.5e-05 0.0065 17.2 2.4 3 23 245 266 243 266 0.96

4 13 0.00028 0.028 15.2 4.6 1 23 271 293 271 293 0.98

5 13 4.9 4.8e+02 1.9 5.7 2 23 300 323 299 323 0.90

6 13 0.00043 0.042 14.7 1.0 3 23 333 354 332 354 0.95

7 13 0.002 0.2 12.5 0.1 1 23 360 383 360 383 0.95

8 13 0.064 6.3 7.8 0.9 5 23 399 418 394 418 0.89

9 13 1.8e-06 0.00018 22.1 0.4 1 23 447 469 447 469 0.98

10 13 1.2e-05 0.0012 19.5 5.4 1 23 475 497 475 497 0.96

11 13 7.9e-06 0.00078 20.1 0.1 2 23 504 525 504 525 0.97

12 13 0.0011 0.11 13.4 0.9 1 23 532 554 532 554 0.99

13 13 0.00054 0.054 14.3 4.6 1 23 560 583 560 583 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	9.3	9.3e+02	1.0	1.9	3	16	58	71	57	73	0.84
2	13	0.00028	0.028	15.2	1.0	1	23	215	238	215	238	0.97
3	13	6.5e-05	0.0065	17.2	2.4	3	23	245	266	243	266	0.96
4	13	0.00028	0.028	15.2	4.6	1	23	271	293	271	293	0.98
5	13	4.9	4.8e+02	1.9	5.7	2	23	300	323	299	323	0.90
6	13	0.00043	0.042	14.7	1.0	3	23	333	354	332	354	0.95
7	13	0.002	0.2	12.5	0.1	1	23	360	383	360	383	0.95
8	13	0.064	6.3	7.8	0.9	5	23	399	418	394	418	0.89
9	13	1.8e-06	0.00018	22.1	0.4	1	23	447	469	447	469	0.98
10	13	1.2e-05	0.0012	19.5	5.4	1	23	475	497	475	497	0.96
11	13	7.9e-06	0.00078	20.1	0.1	2	23	504	525	504	525	0.97
12	13	0.0011	0.11	13.4	0.9	1	23	532	554	532	554	0.99
13	13	0.00054	0.054	14.3	4.6	1	23	560	583	560	583	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCCAAGTGCGATTTcgaaaatggcaacaacaactattggCTGGACTTGTTCCATCCAGCCCGTTGGCAGAGTGAAATGGCGCAAATTCGCATGGAGTTTGTTAACTGGAAGTTACAGATCGCACCTAACGATGGGTTGCCACAGAAAATATGTAGCGATTGTTTTACGAAATTCTGCTCAATTTACACATTTCGCATGGCCTGTCAGGATGCGCAATTAAAGCTCTCAAATATCTTTGATAAAATCGATGCCAACTTGTTGTACGACAAAACTGACGACGAACAGCATGTGGATGATGAGCATAACGATGTCAACATTGTTGAGGATGCTGCGATAACAgagacaacaactgcaacacaaaacacTGCCATAATTGAGGCCAAAGCGTCAACGCCCATAGAAATCTATGTAGAAACGATAAGCATCAacgaaacagcaacagatagcgaaactgcaactgaaacaTTGCAATTAGAAGAGGGAGTAGATGATTTTTCTACAGATTTCAATTCCCTGAACATTAGCTTTGCTTGTAAATTTTGCTACAAACCTGAAGAGAGCTACGAACTGCAGCATTTGCTCTTAGAGCACATTAGTAGCGCCCATGATCCGGATCAGCCATACAATTGTCCGGAATGCACGGAATGTTTCCAAGACGCCGCATCGCGTACGGTGCACATGAAGAGCAGCCATGTTGTGAAGCATTATGGCTGCGAGGTGTGCGGCAAAAAGTACGGCGACCGTCATAATCTACGCCATCACATTGAGAAATATCACTCGGAGACGGATTTCGAGTGCAGCATGTGCGAGAAGCGTTTCTTCACCCGTAAAAGTTTGCATTACCACATGAATTGGCACAAGCCCGAGCGGCAGCTGAGATGTCGACATAGCGGCTGCGACAGACTGTTCATCAATCAACGCCATCTCAAGTGTCATGAGGCAACGCACACAACGGGCTCCCGTAAGAGCGAATACTGCGGCTTTTGTGGCAAAGctTTCATTCATGTGAAGACTTTACGATGGCATATCTATCGACAGCACGGCGGCGAGAAGCCATTCAAGTGTGCTATTTGCACAGAGGTTTTCGCATCGTATGCTGAGAAACGCATACATATGTTAGAGCTGCATACGGAGAATCTAACGCATCAGGAGCGTAGTGAGTGCATGTTCCAATCCTGCCGCCAGGAATTCGACAACGAAAAGCAGCTCATCCATCACATGAGTGTTGAGCATCTGCAACGTGAACCAGCAACTCCCGTTATTGCCAATAACAAACGGGTGCTCCAACGGAAGCGAGAGCGTCAGTATACAGGACTCTTTCAGTGCAGCAATTGTCCGCAACGCTTCAATATGAAGTCTGCCTTGGAGCGACACATGGCAGTGCATTCGGCGGATCGGCTGCATGCGTGTACGCATTGTTCCAAGCGCTATAAGCGTGCCCAGGACTTGAAATGGCACATGAAAACTCATGACAATGAGAAGCCAAATGTCTGCGATGTCTGCGGCAAAGCATTTGCCCTGAAATATGTGCTCACCCAGCATATGCGTAGTCATGAGGTTCTTGAGAAGAATTTCAAGTGTGAGACCTGTGGACGTGCCTATCTATTTGAAAAGTCGCTGCGACTTCATCAGCGTGTCCACACCGGAAACACTTACTACAAATGTGATTTGTGCCAGGAGCGATTTGTGACCCACATCaagtttaaaaCTCATATGAAAAAGATGCACGACACAAGCCAGCCTCATACTAAGGATTCTCTGGATGATTTGATCAACATTGTGATTTCCTAA
Protein Sequence: METCRTCAKCDFENGNNNYWLDLFHPARWQSEMAQIRMEFVNWKLQIAPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANLLYDKTDDEQHVDDEHNDVNIVEDAAITETTTATQNTAIIEAKASTPIEIYVETISINETATDSETATETLQLEEGVDDFSTDFNSLNISFACKFCYKPEESYELQHLLLEHISSAHDPDQPYNCPECTECFQDAASRTVHMKSSHVVKHYGCEVCGKKYGDRHNLRHHIEKYHSETDFECSMCEKRFFTRKSLHYHMNWHKPERQLRCRHSGCDRLFINQRHLKCHEATHTTGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYAEKRIHMLELHTENLTHQERSECMFQSCRQEFDNEKQLIHHMSVEHLQREPATPVIANNKRVLQRKRERQYTGLFQCSNCPQRFNMKSALERHMAVHSADRLHACTHCSKRYKRAQDLKWHMKTHDNEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKMHDTSQPHTKDSLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00507070;
80% Identity: -