Dezo010243.1
Basic Information
- Insect
- Drosophila ezoana
- Gene Symbol
- -
- Assembly
- GCA_035045725.1
- Location
- JAWNOU010000092.1:11379790-11381968[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 5.1e-06 0.00036 21.0 3.4 1 23 79 101 79 101 0.98 2 17 0.0095 0.67 10.7 3.1 1 23 107 129 107 129 0.96 3 17 0.00015 0.011 16.3 2.4 1 23 135 157 135 157 0.98 4 17 2.1 1.5e+02 3.3 2.2 1 12 163 174 163 177 0.89 5 17 7.6e-06 0.00054 20.4 0.1 2 23 181 202 180 202 0.97 6 17 3.7e-05 0.0027 18.2 5.8 1 23 208 230 208 230 0.97 7 17 0.00033 0.023 15.3 1.3 1 23 236 258 236 258 0.98 8 17 0.12 8.4 7.2 0.4 1 23 267 289 267 289 0.92 9 17 0.00074 0.052 14.2 0.2 1 20 426 445 426 446 0.95 10 17 4.4e-08 3.2e-06 27.5 3.9 1 23 461 483 461 483 0.98 11 17 2.5e-07 1.8e-05 25.1 2.1 1 23 489 511 489 511 0.99 12 17 7.2e-06 0.00051 20.5 3.5 1 23 517 539 517 539 0.99 13 17 6.6e-07 4.7e-05 23.8 2.7 1 23 549 571 549 571 0.98 14 17 2.5e-06 0.00018 21.9 4.6 1 23 577 599 577 599 0.99 15 17 1.8e-06 0.00013 22.4 2.1 1 23 605 627 605 627 0.97 16 17 0.00018 0.013 16.1 3.7 2 23 634 655 633 655 0.97 17 17 1.2e-05 0.00082 19.9 4.7 1 23 661 683 661 683 0.98
Sequence Information
- Coding Sequence
- ATGGACGTGAGCTGCGTGAAAATTAAGCAGGAGCAAGATCAGGAGACGCTGCCAATAGATTCGGTCTCGGAGGACGCCAGCAACTTTACGGAGATGGACATAGGACCCATCAAAATAGACCCGGATGTGACTGCAGTGTGTCAGGAACAGGCAGCTGCCGGCAACGTAAGGGATCGGCGAAGAAAGCAAAGACCTGCCGCAACACTGGAGGATTACAGACTGCCCAAGGGACCCCATCAGTGCCCACACTGTCCAAGGCATTTCGAAAGAAGCGACGAACTTACAATACACCTGCAGATCCACACAGATAAATTGCCCTACAAGTGTGTCTACTGTCCGAGCAGTTTTTCCCATAAATCGATTTACACCACGCACATGTACGGACATACTGGCAAATTTCCGCACCAGTGCCCGGACTGTCCGCAGGGCTTCCTGAAATTCAGCGATCTCAAGAAGCATCGACGCACGCACATtgataaaaatgcatttaaatgtcCCCTGTGCCCCAgaaattgcacacacacaggcaaagGCATACTGCAGTGCCCGCAGTGTCCGCGTGTCTTTACGAAGAGCTTCGAGCTGGAAATTCATCTGCAGATCCATAGCGACAAGCTGCCCTACAAGTGTCCGCACTGCCCGAACAGCTTTGCACACAAATCGAACTTCAAAGCGCATGTCTGTGAGCATACCGGCGAGTTTCCATTCAGATGCCGATACTGCCCACGGGGCTTTATGAAGAGGAGCGATTTGTTGAACCACGCGTATACGCACAGCGAGCATACGGATGAGCTGCCATTCAGATGTCTATATTGCCCGCAGAGCTTTCTGGCGGAGAATGATCTGCGAAAGCATTCAGATGTTCATAGAGATAAGATTTCGCAAAACTATCGCAACAAAATGGGCGCTAAATCAGGTTTAAATCGCCACAAAGGCAACGCGCAAAAAGATATCATTGACATTAGCTGTATTAAAAAAGAGCAGGCGGAGCCAAGTGAATCCCTTCCGAAACAAGCCCAAGTCGAGCTCGAAGCTAAAAACGATCCGTCTATCAGCAATACAGTCGACACACCAAAGCTAATACCTCCCGACCGTATAAAAGTGGAGCCTGGAACGGAGGACAGCGGTACAATGGGTTTTACAGCGGACTACAGTGCCTTAGATAAGTCTGATAGTAAAAATGATTTGGCTGAGAGCAATATTGTGCTGGGCCCCATCAAAATAGAACCGGATGAGAGCAGGCCGCCGGAGGAACAGACTTTAGCAAAGCGTTGCTATAAATGCAAAGTTTGTAGCAAGGCATTCCCGGACATAAAAGAGCTGCGCCTCCACGAAAAATGCTACACACACTCAAGCAGACAGACGACAGGCAATAGGCCGTATAAATGCGAGCATTGCTCAAAGACTTTCACGCAGTCGTACAACCTGACGGTGCACATGCGCGGCCATACGGGCGAGCGGCCATACAAATGCCCGCACTGCACGCGCACATTCATCCAGAGCTCGGGCTTGAAGATACACATACGACAACATTCCGGCGAACGGCCATATAAGTGCGCCCATTGTCCGCGCACATTTGCCAACAACTCGAATCGTAAGAAGCACCTGCAGAGTCATGGCATGGAAGTTGCCAGCGATCTGCCGTACAGGTGTCCGCATTGCCCCAAAACCTTTGCACAAAACTCACATTTCCTTGTGCACGTACGTGGACACACCGGCGAACGGCCCTATCAATGCACCTATTGCACCAAGGGCTTCAAGGTCAGCCACGATCTGAAGAAGCATCTGCGCAGCCACACGGGCGAGCGTCCATATGCGTGTCCGCATTGTGCCAAAACCTTTGCGCAGAACTCGCATTTCAATGCCCATCTACGTGGCCATGCCGGCGAACGACCCTTGAAGTGCCCCCACTGCCCGCGCACCTTTCTCAAGGCCTACAATCTCAAGGTGCATCTGTGCACCCATACCGGAGAGCGGCCGTATAAGTGTCCACAGTGTCCGAAAACCTTTACCCAAAACTCTTACTGCAAGACGCATATGCGCGAGcatatgaaatga
- Protein Sequence
- MDVSCVKIKQEQDQETLPIDSVSEDASNFTEMDIGPIKIDPDVTAVCQEQAAAGNVRDRRRKQRPAATLEDYRLPKGPHQCPHCPRHFERSDELTIHLQIHTDKLPYKCVYCPSSFSHKSIYTTHMYGHTGKFPHQCPDCPQGFLKFSDLKKHRRTHIDKNAFKCPLCPRNCTHTGKGILQCPQCPRVFTKSFELEIHLQIHSDKLPYKCPHCPNSFAHKSNFKAHVCEHTGEFPFRCRYCPRGFMKRSDLLNHAYTHSEHTDELPFRCLYCPQSFLAENDLRKHSDVHRDKISQNYRNKMGAKSGLNRHKGNAQKDIIDISCIKKEQAEPSESLPKQAQVELEAKNDPSISNTVDTPKLIPPDRIKVEPGTEDSGTMGFTADYSALDKSDSKNDLAESNIVLGPIKIEPDESRPPEEQTLAKRCYKCKVCSKAFPDIKELRLHEKCYTHSSRQTTGNRPYKCEHCSKTFTQSYNLTVHMRGHTGERPYKCPHCTRTFIQSSGLKIHIRQHSGERPYKCAHCPRTFANNSNRKKHLQSHGMEVASDLPYRCPHCPKTFAQNSHFLVHVRGHTGERPYQCTYCTKGFKVSHDLKKHLRSHTGERPYACPHCAKTFAQNSHFNAHLRGHAGERPLKCPHCPRTFLKAYNLKVHLCTHTGERPYKCPQCPKTFTQNSYCKTHMREHMK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00551015;
- 90% Identity
- iTF_00475347; iTF_00551015; iTF_00531084; iTF_00531085; iTF_00526709; iTF_00490910; iTF_00563305; iTF_00617036; iTF_00534712;
- 80% Identity
- -