Dnov008198.1
Basic Information
- Insect
- Drosophila novamexicana
- Gene Symbol
- -
- Assembly
- GCA_003285875.3
- Location
- NW:2406918-2409603[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 4.4e-06 0.00023 21.0 3.4 1 23 88 110 88 110 0.98 2 17 0.0081 0.43 10.7 3.1 1 23 116 138 116 138 0.96 3 17 0.00015 0.0078 16.2 1.6 1 23 144 166 144 166 0.98 4 17 1.5 77 3.6 2.6 1 14 172 185 172 186 0.89 5 17 2.1e-05 0.0011 18.8 0.1 2 23 190 211 189 211 0.97 6 17 3.2e-05 0.0017 18.2 5.8 1 23 217 239 217 239 0.97 7 17 0.00072 0.038 14.0 2.0 1 23 245 267 245 267 0.97 8 17 0.00059 0.031 14.3 0.4 1 23 276 298 276 298 0.95 9 17 0.00022 0.012 15.6 0.4 1 20 432 451 432 452 0.95 10 17 3.8e-08 2e-06 27.4 3.9 1 23 467 489 467 489 0.98 11 17 2.1e-07 1.1e-05 25.1 2.1 1 23 495 517 495 517 0.99 12 17 6.2e-06 0.00033 20.5 3.5 1 23 523 545 523 545 0.99 13 17 2.8e-07 1.5e-05 24.7 2.4 1 23 555 577 555 577 0.98 14 17 2.2e-06 0.00011 21.9 4.6 1 23 583 605 583 605 0.99 15 17 7.6e-07 4e-05 23.3 2.3 1 23 611 633 611 633 0.98 16 17 0.00013 0.0067 16.4 3.6 2 23 640 661 639 661 0.97 17 17 5.2e-06 0.00028 20.7 5.7 1 23 667 689 667 689 0.98
Sequence Information
- Coding Sequence
- ATGGACGTGAGCTGTGTGAAAATCAAGCAGGAGGAGCAAGAACAGGAGACGCTGCCAATGGATACGGTCTCGGAGGACGCCAGCTGTGCCCAGCTTAAAACTGAAAGCAATTTTACGGAGATGGACATAGGACCCATCAAAATAGACCCGGATGCGACTGCAGTGTGTCAGGGACAGGCAGCTGCCGGCAACGCAAGGGATAGGCGAAAAAAGCAGAGACCTGCCGTAACACTGGAGGATTACAGACTGCCCAAGGGACCCCATCAGTGCCCGCACTGTCCAAGGCACTTCGAAAGAAGCGACGAACTCACAATACACCTGCAGATCCACACAGATAAATTGCCCTACAAGTGCGTCTATTGTCCGAGCAGTTTTTCCCATAAATCGATTTACACCACGCACATGTACGGACATACTGGCAAATTTCCGCACCAGTGCCCGGACTGTCCGCAGGGTTTCCTGAAATACGGCGATCTCAAGAAGCATCGACGCACGCACATCgataaaaatgcattcaaatgtcCACTGTGCCCCAGAAattgcacacacacgagcaAGGGTATACTGCAGTGCCCGCAGTGTCCGCGTGGCTTTACGAAGAGCTTCGAGCTGGAAATTCATCTGCAGATTCATAGCGATAAGCTGCCCTACAAGTGTCCACACTGCCCGAACAGCTTTGCACACAAATCGAACTTTAAAGCGCATGTCTGTGAGCATACGGGCGAGTTTCCATTCAGATGCCGATACTGTCCACGTGGCTTTATGAAGAGGAGCGATTTGCTGAACCACTCGTATACGCACAGCGAGCGTACGGACGAGCTGCCATTCAGATGCCCATATTGCCCGCAGAGCTTTCTGACGGAAAACGATCTGCAGAAGCACTCAGATATTCATAGAGCTAAGATTTCGCAAAACTATCGCAACAAACTAGGCTCTGGCTTAAAACGCCACAAAGACAATGCGCATAACGAAATCATAGACGTAAGCTGTATCAAAAAAGAACGGGCGGAGTCAAGTGAAACCCTTCCGAAAGAAGCCCAAGTCGAGGCCAAAGCTAATCCGTCTATCAGCCAAACAGTCGAAACGCCAGAGCTCATAGCTGCCGACCGCATAAAAGTGGAGCCCGGAACGGAGGATAGCGGTTCTACAGCGGACTACAGTGCATTAGATAAGTCTGATAGTAAAAATGATTTGGCTGAGAGCAACATTGTGCTGGCCCCCATCAAAATAGAACCGGATGAGAGCAGGCCGCCGGAGGAACAGACTTTAGCAACCGTGCGCTCAAAGCGTTGCTATAAATGCAAAGTTTGCAGCAAGGCATTCACGGACATAAAAGAGCTGCGCCTGCACGAAAAATGCTACACACACTCAAGCAGGCAGACGACAGGCAATCGGCCGTATAAATGCGAGCATTGCTCAAAGACTTTCACCCAGTCGTACAACCTGACGGTGCACATGCGCGGCCATACGGGTGAGCGGCCGTACAAATGCCCGCACTGCACGCGCACATTTATCCAGAGCTCGGGCCTGAAGATACACATACGACAACATTCCGGCGAACGGCCATATAAGTGCGCCCATTGTCCGCGCACATTTGCCAACAACTCGAATCGCAAGAAGCACCTGCAGAGTCATGGCATGGAAGTTGCCAGCGATCTGCCGTACAGGTGTCCGCATTGTCCCAAAACCTTTGCACAAAACTCACATTTCATTGTGCACGTACGTGGACACACCGGCGAACGGCCCTATCAATGCACCTATTGCACCAAGGGCTTTAAGGTCAGCCACGATCTGAAGAAGCATCTGCGCAGCCACACGGGCGAGCGTCCGTATGTGTGTCCGCATTGTGCCAAGACCTTTGCGCAGAACTCGCATTTCAATGCCCATCTACGTGGCCATGCCAACGAACGACCACTGAAGTGCCCCCACTGTCCGCGCTCCTTTCTGAAAGCCTACAATCTCAAGGTGCATCTGTGCACCCATACTGGAGAGCGGCCGTACAAGTGTCCACACTGTCCGAAAACCTTTACCCAAAACTCTTACTGCAAGGCGCATATGCGTGAgcatatgaaatga
- Protein Sequence
- MDVSCVKIKQEEQEQETLPMDTVSEDASCAQLKTESNFTEMDIGPIKIDPDATAVCQGQAAAGNARDRRKKQRPAVTLEDYRLPKGPHQCPHCPRHFERSDELTIHLQIHTDKLPYKCVYCPSSFSHKSIYTTHMYGHTGKFPHQCPDCPQGFLKYGDLKKHRRTHIDKNAFKCPLCPRNCTHTSKGILQCPQCPRGFTKSFELEIHLQIHSDKLPYKCPHCPNSFAHKSNFKAHVCEHTGEFPFRCRYCPRGFMKRSDLLNHSYTHSERTDELPFRCPYCPQSFLTENDLQKHSDIHRAKISQNYRNKLGSGLKRHKDNAHNEIIDVSCIKKERAESSETLPKEAQVEAKANPSISQTVETPELIAADRIKVEPGTEDSGSTADYSALDKSDSKNDLAESNIVLAPIKIEPDESRPPEEQTLATVRSKRCYKCKVCSKAFTDIKELRLHEKCYTHSSRQTTGNRPYKCEHCSKTFTQSYNLTVHMRGHTGERPYKCPHCTRTFIQSSGLKIHIRQHSGERPYKCAHCPRTFANNSNRKKHLQSHGMEVASDLPYRCPHCPKTFAQNSHFIVHVRGHTGERPYQCTYCTKGFKVSHDLKKHLRSHTGERPYVCPHCAKTFAQNSHFNAHLRGHANERPLKCPHCPRSFLKAYNLKVHLCTHTGERPYKCPHCPKTFTQNSYCKAHMREHMK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00551015;
- 90% Identity
- iTF_00506249;
- 80% Identity
- -