Basic Information

Insect: Drosophila littoralis
Gene Symbol: -
Assembly: GCA_018903485.1
Location: JAEIGF010000612.1:5880527-5882720[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.5e-06 0.00028 21.0 3.4 1 23 85 107 85 107 0.98

2 17 0.0084 0.52 10.7 3.1 1 23 113 135 113 135 0.96

3 17 0.00015 0.0094 16.2 1.6 1 23 141 163 141 163 0.98

4 17 1.8 1.2e+02 3.3 2.2 1 12 169 180 169 183 0.89

5 17 2.2e-05 0.0013 18.8 0.1 2 23 187 208 186 208 0.97

6 17 3.3e-05 0.0021 18.2 5.8 1 23 214 236 214 236 0.97

7 17 0.00029 0.018 15.3 1.3 1 23 242 264 242 264 0.98

8 17 0.0006 0.038 14.3 0.4 1 23 273 295 273 295 0.95

9 17 5.8e-05 0.0036 17.5 0.8 1 20 431 450 431 451 0.95

10 17 3.9e-08 2.5e-06 27.4 3.9 1 23 466 488 466 488 0.98

11 17 2.2e-07 1.4e-05 25.1 2.1 1 23 494 516 494 516 0.99

12 17 6.3e-06 0.0004 20.5 3.5 1 23 522 544 522 544 0.99

13 17 2.9e-07 1.8e-05 24.7 2.4 1 23 554 576 554 576 0.98

14 17 2.2e-06 0.00014 21.9 4.6 1 23 582 604 582 604 0.99

15 17 1.6e-06 0.0001 22.4 2.1 1 23 610 632 610 632 0.97

16 17 0.00016 0.01 16.1 3.7 2 23 639 660 638 660 0.97

17 17 1.6e-05 0.00098 19.3 6.9 1 23 666 688 666 688 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.5e-06	0.00028	21.0	3.4	1	23	85	107	85	107	0.98
2	17	0.0084	0.52	10.7	3.1	1	23	113	135	113	135	0.96
3	17	0.00015	0.0094	16.2	1.6	1	23	141	163	141	163	0.98
4	17	1.8	1.2e+02	3.3	2.2	1	12	169	180	169	183	0.89
5	17	2.2e-05	0.0013	18.8	0.1	2	23	187	208	186	208	0.97
6	17	3.3e-05	0.0021	18.2	5.8	1	23	214	236	214	236	0.97
7	17	0.00029	0.018	15.3	1.3	1	23	242	264	242	264	0.98
8	17	0.0006	0.038	14.3	0.4	1	23	273	295	273	295	0.95
9	17	5.8e-05	0.0036	17.5	0.8	1	20	431	450	431	451	0.95
10	17	3.9e-08	2.5e-06	27.4	3.9	1	23	466	488	466	488	0.98
11	17	2.2e-07	1.4e-05	25.1	2.1	1	23	494	516	494	516	0.99
12	17	6.3e-06	0.0004	20.5	3.5	1	23	522	544	522	544	0.99
13	17	2.9e-07	1.8e-05	24.7	2.4	1	23	554	576	554	576	0.98
14	17	2.2e-06	0.00014	21.9	4.6	1	23	582	604	582	604	0.99
15	17	1.6e-06	0.0001	22.4	2.1	1	23	610	632	610	632	0.97
16	17	0.00016	0.01	16.1	3.7	2	23	639	660	638	660	0.97
17	17	1.6e-05	0.00098	19.3	6.9	1	23	666	688	666	688	0.98

Sequence Information

Coding Sequence: ATGGACGTGAGCTGTGTGAAAATCAAGCAGGAGCAGGACGCGCTGCCAATGGATTTGGTCTCGGAGGACGCCAGCTGTGCCCAGCTAAAAACTGAAAGCATTTTTACGGAGATTGACATAGGACCCATCAAAATAGACCCGGATGCGACTGCAGTGGGTCAGGGTCAGGCAGCTGCCGGCAACGCAAGAAATCGGCGAAAAAAGCAACGAGGTGCCGCAACACTGGAGGATTACAGACTGCCCAAGGGACCCCATCAGTGCCCGCACTGTCCACGGCACTTCGAAAGAAGCGATGAGCTCACAATACACCTGCAGATCCACACAGATAAATTGCCATACAAGTGCGTCTATTGTCCGAGCAGTTTTTCCCACAAATCGATTTACACCACGCACATGTACGGACATACTGGCAAATTTCCGCACCAGTGCCCGGACTGTCCGCAGGGCTTCCTGAAATACGGCGATCTCAAGAAGCATCGACGCACGCACATTGATAAGAACGCATTTAAATGTCCGCTGTGCCCCAGAAATTGCACACACACGGGCAAAGGCATACTGCAGTGCCCGCAGTGTCCGCGTGGCTTTACGAAGAGCTTCGAGCTGGAAATTCATCTTCAGATCCATAGCGATAAGCTGCCCTACAAGTGCCCGCACTGCCCGAACAGCTTTGCACACAAATCGAACTTTAAAGCGCATGTCTGTGAGCATACGGGCGAGTTTCCATTCAGATGCCGATACTGCCCACGGGGCTTTATGAAGAGGAGCGATTTGTTGAACCACGCGTATACGCACAGCGAGCATACGGACGAGCTGCCATTTAGATGCCCCTATTGCCCACAGAGCTTTCTGACGGAAAACGATCTGCAGAAGCACTCAGATATTCACAGAGATAAGATTTCGCAAAACTATCGCAACAAAATGGGCTCAGGCTTAAAACGCCAGAAAGACAATGCGCATAAAGAGATCATAGACATAAGCTGTATCAAAAAAGAGCGAGCGGAGCCAAGTGAATCCCTTGCGAAACAGCCCCAAGTCGAGCCTGGAGCTAAAAAAGATCCGATAACAGTTGAAACGCCGGAGCTTATAGCTCCCGACCGCATCAAAGTGGAGCCCGGAACGGAGCACAGCGGTACAATGGGCTCTACAGCGGAATACAGTGCCTTAGATAAGTCTGATAGTAAAACTGATTTGGCTGAGAGCAACATTGTGCTGGACCCCATCAAAATAGAGCCGGAGGAGAGCAGGCCGCCGGAGGAACAGACTTTAGCAAGCGTGCGCTCAAAGCGTTGCTATAAATGCAAAGTTTGCAGCAAGGTATTCAAGGACCTAAAAGAACTGCGCCTGCACGAAAAATGCTACACACACTCAAGCAGGCAGACGACAGGTAATCGGCCGTATAAATGCGAGCACTGCTCAAAGACTTTCACCCAGTCGTACAACCTGACCGTGCACATGCGCGGCCATACGGGCGAGCGGCCGTACAAGTGCCCGCACTGCACGCGCACATTTATCCAGAGCTCGGGCCTGAAGATACACATACGACAACATTCCGGCGAACGGCCATATAAGTGCGCCCATTGTCCGCGCACATTTGCAAACAACTCGAATCGTAAGAAGCACCTGCAGAGTCATGGCATGGAAGTTGCCAGCGATCTGCCGTACAGGTGTCCGCATTGTCCCAAAACCTTTGCACAAAACTCCCATTTCATTGTGCACGTACGTGGACACACCGGCGAACGGCCCTATCAATGCACCTATTGCACCAAGGGCTTCAAAGTCAGCCACGATCTGAAGAAGCATCTGCGCAGCCACACGGGCGAGCGTCCATATGCGTGTCCGCATTGTGCCAAAACCTTTGCGCAGAACTCGCATTTCAATGCCCATCTACGTGGCCATGCCAGCGAACGACCATTGAAGTGCCCCCACTGTCCGCGCACCTTTCTCAAGGCCTACAATCTCAAGGTGCATCTGTGCACCCACACCGGAGAGCGGCCGTACAAGTGTCCACATTGTCCGAAAACCTTTACGCAAAACTCTTACTGCAAGACGCATATGCGTGAGCATATGAAATGA
Protein Sequence: MDVSCVKIKQEQDALPMDLVSEDASCAQLKTESIFTEIDIGPIKIDPDATAVGQGQAAAGNARNRRKKQRGAATLEDYRLPKGPHQCPHCPRHFERSDELTIHLQIHTDKLPYKCVYCPSSFSHKSIYTTHMYGHTGKFPHQCPDCPQGFLKYGDLKKHRRTHIDKNAFKCPLCPRNCTHTGKGILQCPQCPRGFTKSFELEIHLQIHSDKLPYKCPHCPNSFAHKSNFKAHVCEHTGEFPFRCRYCPRGFMKRSDLLNHAYTHSEHTDELPFRCPYCPQSFLTENDLQKHSDIHRDKISQNYRNKMGSGLKRQKDNAHKEIIDISCIKKERAEPSESLAKQPQVEPGAKKDPITVETPELIAPDRIKVEPGTEHSGTMGSTAEYSALDKSDSKTDLAESNIVLDPIKIEPEESRPPEEQTLASVRSKRCYKCKVCSKVFKDLKELRLHEKCYTHSSRQTTGNRPYKCEHCSKTFTQSYNLTVHMRGHTGERPYKCPHCTRTFIQSSGLKIHIRQHSGERPYKCAHCPRTFANNSNRKKHLQSHGMEVASDLPYRCPHCPKTFAQNSHFIVHVRGHTGERPYQCTYCTKGFKVSHDLKKHLRSHTGERPYACPHCAKTFAQNSHFNAHLRGHASERPLKCPHCPRTFLKAYNLKVHLCTHTGERPYKCPHCPKTFTQNSYCKTHMREHMK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551015;
90% Identity: iTF_00506249;
80% Identity: -