Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:5663046-5666561[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.042 3.5 8.6 2.4 2 23 2 23 1 23 0.97

2 23 0.0019 0.15 12.9 1.0 1 23 96 119 96 119 0.92

3 23 2.6 2.2e+02 2.9 1.3 2 22 127 147 126 147 0.95

4 23 0.44 37 5.4 1.5 1 23 156 178 156 178 0.97

5 23 0.27 23 6.0 0.5 3 23 190 210 189 210 0.97

6 23 0.0022 0.18 12.6 0.6 1 23 292 315 292 315 0.97

7 23 0.0032 0.27 12.1 0.2 2 22 325 345 322 345 0.90

8 23 0.00094 0.079 13.8 1.6 2 23 403 424 402 424 0.97

9 23 7.5e-06 0.00062 20.4 2.5 1 23 432 454 432 454 0.99

10 23 0.0036 0.3 11.9 1.9 1 23 607 629 607 630 0.95

11 23 0.0085 0.71 10.8 0.5 2 22 638 658 637 658 0.95

12 23 0.034 2.8 8.9 0.6 1 23 667 690 667 690 0.90

13 23 1.5e-05 0.0013 19.4 1.2 2 23 713 734 712 734 0.97

14 23 0.00012 0.0099 16.6 1.2 1 23 741 763 741 763 0.98

15 23 0.025 2.1 9.3 0.0 2 21 790 809 789 810 0.93

16 23 0.01 0.83 10.5 3.9 1 23 856 879 856 879 0.96

17 23 0.0056 0.47 11.3 0.5 1 23 916 939 916 939 0.96

18 23 0.00024 0.02 15.6 1.5 1 23 963 986 963 986 0.97

19 23 4.6e-06 0.00038 21.0 0.2 2 23 1014 1035 1013 1035 0.95

20 23 0.00013 0.011 16.5 2.9 1 23 1041 1063 1041 1063 0.99

21 23 3.1e-06 0.00026 21.6 2.0 1 23 1069 1091 1069 1091 0.97

22 23 1.6e-07 1.3e-05 25.6 2.4 1 23 1097 1119 1097 1119 0.99

23 23 0.0011 0.09 13.6 0.1 1 21 1125 1145 1125 1149 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.042	3.5	8.6	2.4	2	23	2	23	1	23	0.97
2	23	0.0019	0.15	12.9	1.0	1	23	96	119	96	119	0.92
3	23	2.6	2.2e+02	2.9	1.3	2	22	127	147	126	147	0.95
4	23	0.44	37	5.4	1.5	1	23	156	178	156	178	0.97
5	23	0.27	23	6.0	0.5	3	23	190	210	189	210	0.97
6	23	0.0022	0.18	12.6	0.6	1	23	292	315	292	315	0.97
7	23	0.0032	0.27	12.1	0.2	2	22	325	345	322	345	0.90
8	23	0.00094	0.079	13.8	1.6	2	23	403	424	402	424	0.97
9	23	7.5e-06	0.00062	20.4	2.5	1	23	432	454	432	454	0.99
10	23	0.0036	0.3	11.9	1.9	1	23	607	629	607	630	0.95
11	23	0.0085	0.71	10.8	0.5	2	22	638	658	637	658	0.95
12	23	0.034	2.8	8.9	0.6	1	23	667	690	667	690	0.90
13	23	1.5e-05	0.0013	19.4	1.2	2	23	713	734	712	734	0.97
14	23	0.00012	0.0099	16.6	1.2	1	23	741	763	741	763	0.98
15	23	0.025	2.1	9.3	0.0	2	21	790	809	789	810	0.93
16	23	0.01	0.83	10.5	3.9	1	23	856	879	856	879	0.96
17	23	0.0056	0.47	11.3	0.5	1	23	916	939	916	939	0.96
18	23	0.00024	0.02	15.6	1.5	1	23	963	986	963	986	0.97
19	23	4.6e-06	0.00038	21.0	0.2	2	23	1014	1035	1013	1035	0.95
20	23	0.00013	0.011	16.5	2.9	1	23	1041	1063	1041	1063	0.99
21	23	3.1e-06	0.00026	21.6	2.0	1	23	1069	1091	1069	1091	0.97
22	23	1.6e-07	1.3e-05	25.6	2.4	1	23	1097	1119	1097	1119	0.99
23	23	0.0011	0.09	13.6	0.1	1	21	1125	1145	1125	1149	0.91

Sequence Information

Coding Sequence: ATGCAGTGCAAATTGTGCGGCTTGAAGTGCCAGCGAATGCAGGAGCTTCGATCCCATTTAGAGAGCCACGTCCACACGGACAGTTTGTTCAGTCTGCGAGCGGACAACGATGTGGTCAAAGAACATTTTGCCATTGGCCCATTTGACCTGGAAAAGATCAAGCAGCAAATTCGCTCGGAAATAGCCGAAGGGCAGCTGGAAAAGTACTCTTCAGTGGTCAATTTCCATGGCTACGAGCTGTGCCTGAGCGATTCTGACGATGAGCCTGCCGGTGGAGAGCCACCGTACCTTTGTGACCTCTGCAATCTGTCGTACACTCGCAAATATCGACTGATGCGGCACACCCTGGAGGAGCACACCCAATCGCCCATTTCCCAGCGCTGCAACCTCTGCAAAGTGGGTTTTGTGTGTGCAAAGCTCTTCGAACAGCATCAGCGAACCCAGTGCCAAAGCAAAGGGAAGCGCTATCGTTGCCGTAAGTGTCCAGGGAAGTTCATGTGGCTGGAGAATCTGGAGCGGCATGCCTGCTCACATCGCAAGGAGGAGCAGTCGTACAGGCAAATACTCTGTTGCCTGTGCGATGCCCAGCTTCCCAGCTTAAGGCAGCTGCGCGCTCACCTGGCTACCCATCGACATGGATTGAGCGGTATTGATCCTGAGCAGAAATCTGCCTTCTTCCGTTCTTACTATCCCAACGGATTGGGCTGCAGCCTCTCCGAGCTGAGCTCACGCATAGCTGGGGACTATGAGGCCCAAGACTTTGGACGCTACTACAACGCCTGCACGGGAAGTGGTCAAGAGTTGGATCTCTTTGATTCTGATACAGAGGAGACggatgaggcagacaaaacagAGGAAAAGCCAAAACCCTCGCACACCTGCCTGCTCTGTGGAGAGACTACTATTCGCCTGCTCAATCTGCTGCAACATCAAAGGATACTCCACTCCGACGAGGGCACCACGTACCCCTGCTCTTGCCAGGATTGTGGCGCTGGCTTTGTCTCAGAGCCCTTGCTACAGCAACATCGAAGACGTTCCTGTGCCAAAAAGCACTCAAAATACCACTGCCAGCGATGCAATCTTCATTTTGTGTGGCAATCGAACCACGAGCAACATCTGCGCTTGTACCACGACAAGGATGGGGATCAGGAGCAGTCGGAGGACTGCCAGCAGGGTGGAAAACATAAATCTTCGGCCGCCAAGCTTCAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTCACCCGTCACAAGCGAATGCATCGCCCACCGTCGGCAGCCCAATACGAGTGTGCCTATTGCGACCGGAAGTTTCACCGCAAAGATGGCCTCAAGTCCCACCTGCGGGTGCacaacgagcagcagcaggagacaGTGAATGAGGAGCCGTCTTGCGCCCAATCGACATCTACGAACAGTATTCAGAAAATAGCCGGGGAGCAGCTGACCCAACTATGCCGTCCAAATGGTTGCAAGCAAATCCAGTGCATGATTTGCCTATCGCGTCACTCAAAGATCGCCGATTTGAGGAATCATCTAAGCACGCACCAATATGGTGTGTGCTTTCCACAGGAGAGAGATATTCCCAGTGCCTCGCGCTCGTTGTATCCGGAACTGGGCACTGCCCTGGATaagcaggagctggagaagAGGATCATGAGCGATGTGGCCAGCGGCTTGGAGTTGGAGCGATTCATTTCCATAACCAACGAGGCTGGCATTGAGCTCTCTCTTGAGAGCAGTGAAACGGAAACGGATTCAGAACAGGACGAGGATGACGAGAGCTCCGAGGAAGCTGACCAGCAGCGGTACGCCTGCAACATCTGCCAGGTGGAGGTGAGGCGAAAGCATCAATTGTATGCCCACCAGTTGGAGCATCACCAGTGGGAGGAGGCTTCGCTTGTGTGTGCCCACTGTCAGGCGAGATTCGTGAGTGAAACGCTGCTGGAGCATCACTACAGGACCCTCTGCCGGAACCCACAGAAGCGTTTCCAGTGCCGAAAGTGTCCGCTACGCTTCCGCTGGCGGGAGAACCTGAAGCTGCACGCAAGTGCCTCCCATCAGCAAATAGGGCAGCCCCAAGCTGCAGAGGAACAGAGGAACGGCATCCAGACTGAGTTCGACCTCCAGTGTGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCATACGTTGATGCATGCCCAGGAATCGAGCATATATCGTTGTCGTTGGTGTGCCCGCCGCTTCTACAGGAAGGCCAATCTCCTGCAGCACATTGAGCGGCATGGCATCGGAGCTAGCCAGCTGCCCTACGCGGAAGCTCTCCTCAATGCCTATGGTCAACCCAATGGCCAGAAGAGCGTGGAGTGCAAGGTGTGCAGCTTGAGCTTCCCCAGTATTGCTGCACTTCGCGTCCATCTGGAGACCATGGCGTCGGGAAGTCACCACGAACTATCGTCCCTGCAGAACTACTCGATAACCAACCAAATGGGATTCGAGCTGCACTTGGATGACTCGGAGACGGATGAGGAGGAGTCCAAGCCACCAGGCACGCCTGCTGTCTACACCTGCGGCATGTGCCAGCTCCGGTGTGTGCGAAAGTACGAGCtgcatcagcaccagcaggcCATGCACAGGCTGGAGAAGATCCCCAATGGCTGCGATCTGTGCATTTTCAAGAGTGTCTCTCCCGATCTTATCGCGCATCACAAGCGAGTGCAGTGCCACAACCGCGAGAAGCAGTTCACTTGCGCCAAATGCGGCTACAAGTTTATGTGGGAGTCCAATCTCTTGCTGCACATGCAGCTGCAACATGGCAAGACCGAAGAACAGGATGATCCACCCCTGGATGAGCCCGTGGAGCAGAAGGCTCTGTGTCCAGTCTTCCAGTGCGGCCTCTGCCCAAGGAAATACAATCGCAAGGATCGGCTGACGGCCCATGTGAAGAAGTTCCACAACCCAGTGGTAGGGAGCGCTCCGAGCACCATACGGGCTGCTCCAATCCGACCAACCTCGCCCAAGGAGCCGAAACGCTTCCTTTGCGCCTTCTGTGGCAAGGCTGTGAGCTCCTCCTCCAACCTCATCATCCACATGCGTCGGCACACGGGCGAGAAGCCTTTCAAGTGTGACTACTGCGAAATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGAACGCACACCGGGGAACGGCCCCACATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCTACAAACTGCAGCAGCACATGCGCATCCACAACGGCGAGCGGCCCTACAAGTGCACCTACTGCGAAAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGCCGCCACACGGGCGAGCGTCCCTATCAGTGCGGGGTCTGTGGCGAGCGTTTCATCCAGGGTACGGCCCTGAAGAATCATCGCCTACAGCAGGGCCACTATGACGAGGCCAGCCAAGGAGCGGCAGAGTCCTCAAGGCGCACGGTCCTAGAGCAATTTACAGTTTAG
Protein Sequence: MQCKLCGLKCQRMQELRSHLESHVHTDSLFSLRADNDVVKEHFAIGPFDLEKIKQQIRSEIAEGQLEKYSSVVNFHGYELCLSDSDDEPAGGEPPYLCDLCNLSYTRKYRLMRHTLEEHTQSPISQRCNLCKVGFVCAKLFEQHQRTQCQSKGKRYRCRKCPGKFMWLENLERHACSHRKEEQSYRQILCCLCDAQLPSLRQLRAHLATHRHGLSGIDPEQKSAFFRSYYPNGLGCSLSELSSRIAGDYEAQDFGRYYNACTGSGQELDLFDSDTEETDEADKTEEKPKPSHTCLLCGETTIRLLNLLQHQRILHSDEGTTYPCSCQDCGAGFVSEPLLQQHRRRSCAKKHSKYHCQRCNLHFVWQSNHEQHLRLYHDKDGDQEQSEDCQQGGKHKSSAAKLQCDECEKVFIWHKDLTRHKRMHRPPSAAQYECAYCDRKFHRKDGLKSHLRVHNEQQQETVNEEPSCAQSTSTNSIQKIAGEQLTQLCRPNGCKQIQCMICLSRHSKIADLRNHLSTHQYGVCFPQERDIPSASRSLYPELGTALDKQELEKRIMSDVASGLELERFISITNEAGIELSLESSETETDSEQDEDDESSEEADQQRYACNICQVEVRRKHQLYAHQLEHHQWEEASLVCAHCQARFVSETLLEHHYRTLCRNPQKRFQCRKCPLRFRWRENLKLHASASHQQIGQPQAAEEQRNGIQTEFDLQCGECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRKANLLQHIERHGIGASQLPYAEALLNAYGQPNGQKSVECKVCSLSFPSIAALRVHLETMASGSHHELSSLQNYSITNQMGFELHLDDSETDEEESKPPGTPAVYTCGMCQLRCVRKYELHQHQQAMHRLEKIPNGCDLCIFKSVSPDLIAHHKRVQCHNREKQFTCAKCGYKFMWESNLLLHMQLQHGKTEEQDDPPLDEPVEQKALCPVFQCGLCPRKYNRKDRLTAHVKKFHNPVVGSAPSTIRAAPIRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYDEASQGAAESSRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00473937; iTF_00473940; iTF_00611480; iTF_00564064; iTF_00517866; iTF_00474640;
90% Identity: iTF_00473937; iTF_00473940;
80% Identity: -