Basic Information

Insect: Drosophila tristis
Gene Symbol: ZNF296
Assembly: GCA_018150885.1
Location: JAECWT010000189.1:428239-432875[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0034 0.22 11.8 0.4 3 23 131 151 130 151 0.98

2 26 0.0072 0.48 10.8 1.1 1 23 157 179 157 179 0.97

3 26 0.053 3.5 8.0 1.8 2 23 211 232 210 232 0.96

4 26 0.00018 0.012 15.8 1.8 1 23 305 328 305 328 0.94

5 26 4 2.7e+02 2.1 1.1 2 22 336 356 335 356 0.94

6 26 0.44 30 5.1 1.5 1 23 365 387 365 387 0.97

7 26 0.18 12 6.4 0.4 3 23 399 419 397 419 0.95

8 26 0.035 2.4 8.6 1.2 1 23 500 523 500 523 0.96

9 26 0.0083 0.55 10.6 0.1 2 22 533 553 530 553 0.90

10 26 0.093 6.2 7.2 4.5 1 23 562 585 562 585 0.97

11 26 0.00094 0.063 13.5 1.6 2 23 611 632 610 632 0.97

12 26 4.7e-06 0.00031 20.8 4.5 1 23 640 662 640 662 0.99

13 26 0.0027 0.18 12.1 0.9 1 23 817 840 817 840 0.94

14 26 0.0095 0.63 10.4 0.2 2 22 848 868 847 868 0.95

15 26 0.33 22 5.5 0.5 1 23 877 900 877 900 0.87

16 26 1.5e-05 0.001 19.2 1.2 2 23 922 943 921 943 0.97

17 26 5e-05 0.0034 17.5 2.5 1 23 950 972 950 972 0.98

18 26 0.0074 0.49 10.7 0.0 2 21 999 1018 998 1019 0.93

19 26 0.01 0.67 10.3 3.9 1 23 1065 1088 1065 1088 0.96

20 26 0.013 0.9 9.9 0.4 1 23 1125 1148 1125 1148 0.95

21 26 0.00024 0.016 15.4 1.5 1 23 1172 1195 1172 1195 0.97

22 26 4.6e-06 0.00031 20.8 0.2 2 23 1221 1242 1220 1242 0.95

23 26 0.00013 0.0085 16.3 2.9 1 23 1248 1270 1248 1270 0.99

24 26 3.1e-06 0.0002 21.4 2.0 1 23 1276 1298 1276 1298 0.97

25 26 1.6e-07 1.1e-05 25.4 2.4 1 23 1304 1326 1304 1326 0.99

26 26 0.0045 0.3 11.4 0.4 1 21 1332 1352 1332 1356 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0034	0.22	11.8	0.4	3	23	131	151	130	151	0.98
2	26	0.0072	0.48	10.8	1.1	1	23	157	179	157	179	0.97
3	26	0.053	3.5	8.0	1.8	2	23	211	232	210	232	0.96
4	26	0.00018	0.012	15.8	1.8	1	23	305	328	305	328	0.94
5	26	4	2.7e+02	2.1	1.1	2	22	336	356	335	356	0.94
6	26	0.44	30	5.1	1.5	1	23	365	387	365	387	0.97
7	26	0.18	12	6.4	0.4	3	23	399	419	397	419	0.95
8	26	0.035	2.4	8.6	1.2	1	23	500	523	500	523	0.96
9	26	0.0083	0.55	10.6	0.1	2	22	533	553	530	553	0.90
10	26	0.093	6.2	7.2	4.5	1	23	562	585	562	585	0.97
11	26	0.00094	0.063	13.5	1.6	2	23	611	632	610	632	0.97
12	26	4.7e-06	0.00031	20.8	4.5	1	23	640	662	640	662	0.99
13	26	0.0027	0.18	12.1	0.9	1	23	817	840	817	840	0.94
14	26	0.0095	0.63	10.4	0.2	2	22	848	868	847	868	0.95
15	26	0.33	22	5.5	0.5	1	23	877	900	877	900	0.87
16	26	1.5e-05	0.001	19.2	1.2	2	23	922	943	921	943	0.97
17	26	5e-05	0.0034	17.5	2.5	1	23	950	972	950	972	0.98
18	26	0.0074	0.49	10.7	0.0	2	21	999	1018	998	1019	0.93
19	26	0.01	0.67	10.3	3.9	1	23	1065	1088	1065	1088	0.96
20	26	0.013	0.9	9.9	0.4	1	23	1125	1148	1125	1148	0.95
21	26	0.00024	0.016	15.4	1.5	1	23	1172	1195	1172	1195	0.97
22	26	4.6e-06	0.00031	20.8	0.2	2	23	1221	1242	1220	1242	0.95
23	26	0.00013	0.0085	16.3	2.9	1	23	1248	1270	1248	1270	0.99
24	26	3.1e-06	0.0002	21.4	2.0	1	23	1276	1298	1276	1298	0.97
25	26	1.6e-07	1.1e-05	25.4	2.4	1	23	1304	1326	1304	1326	0.99
26	26	0.0045	0.3	11.4	0.4	1	21	1332	1352	1332	1356	0.91

Sequence Information

Coding Sequence: ATGCGGCTGCAGGAATGTCTGGAGGAGAGCCCCATTGACATACCAGAGGAGCAGATTAAAACAGAGATCGACATTGATGAGGAGCAAAGAGATTTCAGTGATTCTGGAGATGCACAGAGATTGTCTGATGTGGATGTGGAGTCGGCTGGCGCGTGCTCTGTTGAGTACAAATGGACGCCAGAAAGTGACACCGAGGATGAAAATGCCTCAAACGATGAAGATGATGATGTGGATGAGCAGCAGCAGCCCTACGCCTTGCGACGAAGTTCACGCCAAGCCAAGCCACAGGCGGATAGTGAAGAGGAGGATGTGTTGCCCAGCAAGCGGCGCCGTGGACGCCCTCCTGGTCTCGCCAAAAGCAAGTCTAGGAATTGCGAAGGTCGTCATGGCTGTGATGTGTGCGGCAAAACGTTTTCCTGGTTCAGAGACATGAAGCGACACGCTCGTGTCCATTATGAGAAGGCCTCGTTCGTCTGCGACATCTGTGGCAAGGGATTCTTGCGCAAGGACAAGTACACGTTCCATCTACGCTCCCACGAGAAGCGAGAGGCCAAGTGCCAGGCCCTCCAGCTGAAAAACGAGTGGAGATACGCGGAGCGTTTGTACAGCTCCGGGCGACTAAAGCGAATACAATGCAAATTGTGTGGCCTGAAATGCCAGCGAATGCAGGAGCTCCGATCCCATTTGGTGAGTCACACTCGCACGGATGGTTTGACCACTCTGCGTGCGGACAGCGATGTGGTGAAGGTACATTTTGCCAGTGTGCCATTTGACCTGGAAACGATCAAGCAGCGGGTCTGCACGGAAATAGCCGCAGGGCAGCTGGAAAAGTACTCGTGTGTGGTTAATTTCCACGGCTACGAGCTGTGCCTGAGCGACTCAGACGATGAGCCTGCCGGTGGAGAGCCACCGTATCGGTGTGACCTGTGCAATCAGTCGTACACGCGAAAATATCGCCTGATGCGTCACACACTGGAGGAGCACACCCAATCGCCCATTTCGCAGCGTTGCAACCTGTGCAAAGTTGGTTTCGTGTGTGCCAAGCTCTTTGCACAGCACCAGCGGACCCAGTGCCAGAGCAAAGTGAAGCGCTATCGCTGCCGCAAGTGTCCGGGGAAGTTCATGTGGCTGGAGAATCTGGAGAGGCATGCCTGTTCCCATCGCAAGGAGGAGCAGTCGTACAGGCAAATCATCTGCTGTCTGTGCGATGCTCAGCTGTACAGCTTGAGGCAGCTGCGCGCACACCTGGCCACCCATCGACATGGATTGAGTGGCATTGATCCGGAGCAGAAGACCACCTTCTTCCGTTGCTACTATCCCAACGGATTGGGTTGCAGCCTCTCCGAGCTGAGCTCCCGCATAGCTGTGGACTATGAGGCCCAGGACTTTGGACGCTACTACAACGCCTGCACTGGAAGTGGTGAAGAGCTGGATCTCTTTGACTCCGACACGGAGGATGGCGAGGGGCACGAAACAGACGAAAAGCCGAAACTCTTGCACAGCTGCCTGCTGTGTGGAGAGACTTCCATTCGTCTGCTCAAGCTGCTGCAACATCAGAGGAGACTCCACTGCGCAGAGGACACCACGTACCCCTGCTCTTGCCAGGATTGTGGCGCTGGCTTCGTGTCCGATGCCTTGCTGGAGCAACATCGCAGACGATCCTGTGCTAAGAAGCACTCGAAATACCACTGCCAGCAATGCAATCTTCATTTTGTGTGGCAATCGAACTACGAGCAACATCTGCGATTGTACCACTCCAAGGATGAGGATCAGGAGCAGTCGGAGGACTGCCAGCAGGGTAGAAAATTTAAATCTTCGTCCGTCAAGCTACAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTCACGCGTCACAAGCGAATGCACCGCCCTCCGTCGGCAGCCCAATACGAGTGTGGCCATTGCGACCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCCCACATGCGGGTGCACAACGAACAGCAGCAGCAGGAGGCGGCTGTAAATGAGGAGCAGCGTTCTTCCGCCCAGTCGACATCTACGAACAGTATGCAGCGAATGACCGGGGAGCAGCTGACCCAACTATGCCGTCCAAATGGCTGCAAGCAAATCCAGTGCATGATTTGCCTCTCGCGCCACTCGAAGATCGCCGACTTGAGGACTCACCTAAGCGGGCACCAGTATGGCGCGGGCTTTCCACCGGACAGGGATATTGGCAGTGCCTCGCGTTCGCTGTATCCCGAACTGGGCACTGCCCTGGATAAGCAGGAGCTGCTGGAGAGGATCATGAGCGATATAGCAAGCGGCTTGGAGTTGGAGCGATTCATTTCCATAACCAACGAGGCTGGCATTGAGCTCTCGCTGGAGAGCAGTGAAACGGAAACGGATTCAGAGCAGGAGGATGACGAGAGTTCCGAGGAAGTGGACCAGCAGCGGTACGCCTGCAACATTTGCCAGTTGGAGGTGAAGCGGAAGCATCAGTTGTATGCCCACCAGTTGGAGCAACACCAGTGGGAGGAGGCGTCGCTTGTGTGCGCCCACTGCCAGGCAAGATTCGTGAATGAGGCACTGCTGGCGCATCACTACCGGACACTCTGCCGGAATACCCAGAAGCGCTTCCTGTGCCGCAAATGTCCGCTACGCTTCCGCTGGCGTGAAAACCTAAAGCTGCACGCCAGTGCCAGCCATCCGCAAAGGGAACAGATCCAACCAGCTGCAGAAGAACCCAGCATTAAGGGTGAGTTCGAGCTGCAGTGTGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCACACGCTGATGCATGCCCAGGAATCGAGCATTTATCGCTGTCATTGGTGTGCCCGCCGGTTCTACAGGAAGGCCAATCTCCTGCAGCACATTGAGCGGCACGGCATCGGAGCCAGCCAGCTGCCCTACGCGGAAGCTCTCCTCAATGCCTATGGCCATCCCAATGGGCAGAAGAGTGTGGAGTGCAAAGTGTGCAGCCTGAGCTTCTCCAGCATCGCTGCCCTTCGCGTTCACCTGGAGACCATGGCGTCGGGCAGTCACCACGAGCTGTCGTCCCACCAGAACTACTCGATAACCAACCATATGGGATTCGAGCTGCACTTGGATGACTCGGAGACGGATGAGGAGGAGTCCAAGCCACCGGGCACGCCTGCATCCTACACGTGTGGCATGTGCCAGCTGCGGTGTGTGCGAAAGTACGAGCTGCATCAGCACCAGCAGGCCATGCACAGGCTGGAGAAGATCCCCGATGGCTGCGATCGGTGCATTTTCAAGAGCGTCTCCCCCGATCTTATCGCGCACCACAAGCGCGTGCAGTGCCACAACCAGGAGAAGCAGTTCAACTGCGCCAAATGCGGCTACAAGTTCATGTGGGAGTCCAATCTGCTGCTGCACATGCAGCTGCAGCATGGCAAGGCCGAAGAACGGGAAGACCCACCCCTGGATGAGCCCGTGGAGCAGAAGACTGTGTGCCAGATCTTTCAGTGCGGCCTCTGCCCCAGGAAGTACAATCGCAAGGATCGGCTGACGGCGCATGTGAAGAAGTTTCACAATCCAGTGGCAGGAACCCCAAGCGTCATACGGGCACCCATCCGTCCAGCGTCGCCCAAGGAGCCGAAACGCTTCCTTTGCGCCTTCTGTGGCAAGGCTGTGAGCTCCTCCTCGAACCTCATCATCCACATGCGACGGCACACGGGCGAGAAGCCCTTTAAGTGCGACTACTGCGAAATGGCCTTCCCGCGCTCCTCCGATCTTCAGTGCCATCGACGAACGCACACCGGCGAGCGGCCCCACATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCTACAAACTGCAGCAGCACATGCGCATCCACAGCGGCGAACGGCCCTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGATCTGACGCTCCACATCCGCCGCCACACGGGCGAGCGTCCGTATCATTGTGGGGTATGTGGCGAGCGTTTTATCCAGGGCACGGCCCTCAAGAACCATCGACTGCAGCAAGGACACTATGACGAGGCCGGCCAGGGAGCTGCAGAGTCCGCAAGGCGTACGGTCTTAGAGCAATTTGCCGTATAG
Protein Sequence: MRLQECLEESPIDIPEEQIKTEIDIDEEQRDFSDSGDAQRLSDVDVESAGACSVEYKWTPESDTEDENASNDEDDDVDEQQQPYALRRSSRQAKPQADSEEEDVLPSKRRRGRPPGLAKSKSRNCEGRHGCDVCGKTFSWFRDMKRHARVHYEKASFVCDICGKGFLRKDKYTFHLRSHEKREAKCQALQLKNEWRYAERLYSSGRLKRIQCKLCGLKCQRMQELRSHLVSHTRTDGLTTLRADSDVVKVHFASVPFDLETIKQRVCTEIAAGQLEKYSCVVNFHGYELCLSDSDDEPAGGEPPYRCDLCNQSYTRKYRLMRHTLEEHTQSPISQRCNLCKVGFVCAKLFAQHQRTQCQSKVKRYRCRKCPGKFMWLENLERHACSHRKEEQSYRQIICCLCDAQLYSLRQLRAHLATHRHGLSGIDPEQKTTFFRCYYPNGLGCSLSELSSRIAVDYEAQDFGRYYNACTGSGEELDLFDSDTEDGEGHETDEKPKLLHSCLLCGETSIRLLKLLQHQRRLHCAEDTTYPCSCQDCGAGFVSDALLEQHRRRSCAKKHSKYHCQQCNLHFVWQSNYEQHLRLYHSKDEDQEQSEDCQQGRKFKSSSVKLQCDECEKVFIWHKDLTRHKRMHRPPSAAQYECGHCDRKFHRKDGLKSHMRVHNEQQQQEAAVNEEQRSSAQSTSTNSMQRMTGEQLTQLCRPNGCKQIQCMICLSRHSKIADLRTHLSGHQYGAGFPPDRDIGSASRSLYPELGTALDKQELLERIMSDIASGLELERFISITNEAGIELSLESSETETDSEQEDDESSEEVDQQRYACNICQLEVKRKHQLYAHQLEQHQWEEASLVCAHCQARFVNEALLAHHYRTLCRNTQKRFLCRKCPLRFRWRENLKLHASASHPQREQIQPAAEEPSIKGEFELQCGECNRSFKMQKDLTRHTLMHAQESSIYRCHWCARRFYRKANLLQHIERHGIGASQLPYAEALLNAYGHPNGQKSVECKVCSLSFSSIAALRVHLETMASGSHHELSSHQNYSITNHMGFELHLDDSETDEEESKPPGTPASYTCGMCQLRCVRKYELHQHQQAMHRLEKIPDGCDRCIFKSVSPDLIAHHKRVQCHNQEKQFNCAKCGYKFMWESNLLLHMQLQHGKAEEREDPPLDEPVEQKTVCQIFQCGLCPRKYNRKDRLTAHVKKFHNPVAGTPSVIRAPIRPASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYHCGVCGERFIQGTALKNHRLQQGHYDEAGQGAAESARRTVLEQFAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00471775;
90% Identity: iTF_00474640;
80% Identity: -