Dobs011932.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila obscura
Gene Symbol
ZNF296
Assembly
GCA_018151105.1
Location
NW:3213007-3217673[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0018 0.11 12.7 1.1 1 23 215 237 215 237 0.96
2 26 0.008 0.49 10.7 1.1 1 23 243 265 243 265 0.97
3 26 0.024 1.5 9.1 2.1 2 23 297 318 296 318 0.97
4 26 0.0055 0.33 11.2 1.3 1 23 391 414 391 414 0.94
5 26 3.6 2.2e+02 2.3 1.2 2 22 422 442 421 442 0.95
6 26 0.49 30 5.0 1.5 1 23 451 473 451 473 0.97
7 26 0.2 12 6.3 0.4 3 23 485 505 483 505 0.95
8 26 0.016 0.99 9.7 0.7 1 23 586 609 586 609 0.96
9 26 0.0078 0.48 10.7 0.1 2 22 619 639 616 639 0.90
10 26 0.1 6.4 7.2 4.5 1 23 648 671 648 671 0.97
11 26 0.0011 0.069 13.3 1.3 2 23 697 718 696 718 0.97
12 26 7.5e-06 0.00046 20.2 4.4 1 23 726 748 726 748 0.99
13 26 0.0031 0.19 12.0 0.9 1 23 903 926 903 926 0.94
14 26 0.014 0.87 9.9 0.2 2 22 934 954 933 954 0.95
15 26 0.023 1.4 9.2 0.7 1 23 963 986 963 986 0.92
16 26 1.7e-05 0.001 19.1 1.2 2 23 1008 1029 1007 1029 0.97
17 26 0.00013 0.0081 16.3 1.2 1 23 1036 1058 1036 1058 0.98
18 26 0.0083 0.5 10.6 0.0 2 21 1085 1104 1084 1105 0.93
19 26 0.011 0.68 10.2 3.9 1 23 1151 1174 1151 1174 0.96
20 26 0.015 0.92 9.8 0.4 1 23 1211 1234 1211 1234 0.95
21 26 0.00027 0.017 15.3 1.5 1 23 1258 1281 1258 1281 0.97
22 26 5.1e-06 0.00031 20.7 0.2 2 23 1307 1328 1306 1328 0.95
23 26 0.00014 0.0087 16.2 2.9 1 23 1334 1356 1334 1356 0.99
24 26 3.4e-06 0.00021 21.3 2.0 1 23 1362 1384 1362 1384 0.97
25 26 1.8e-07 1.1e-05 25.3 2.4 1 23 1390 1412 1390 1412 0.99
26 26 0.0012 0.074 13.2 0.1 1 21 1418 1438 1418 1442 0.91

Sequence Information

Coding Sequence
ATGCTGCCCAGCAATATTTGCCGTACGTGTGCCCTGCATAAAAACAATTTGCTGGCCCTGTCCACTTCCTTGGATCAGTATACgaataaaagtttttatgATGTACTCCAAGAACTGACGCAGATCGATCCTCTGCTGGAGAATGCTGACGACAATCTGCCCCAGCATCTGTGTACAGATTGCTTGGACAGGCTGAAGAACGCGTACGCCTTTGTGGAGCAGGCCAGAAAAGTCAATGGAGAGCTGCTGATGCGGCTGCAGGAATGTCTGGAGGAGAGCCCCATTGACATACCAGAGGAGCAGATTAAAACAGAGATCGACATTGATGAGGAGCAAAGAGATTTCAGTGATTCTGGAGAGGCACAGGGATTGtctgatgtggatgtggagtCGGCTGGCGCGTGCTCTGTTGAGTACAAATGGACGCCAGAAAGTGACAGCGAGGATGAAAATGCCGATGCACTCTCAAACGATGAAGATGATGATGgggatgagcagcagcagccctatGCCTTGCGACGAAGTTCACGCAAAGTCAAGCCACAGGCGGATAGTGAAGTGGAGGAACAGCCGCCCAACAAGCGGCGTCGCGGACGTCCTCCTGGTCTCGCCAAAAGCAAGTCTAGGAATTCCGAAGGTCGTCATGCCTGTGAGGTGTGCGGCAAAACGTTTTCCTGGTTCCGAGACATGAAGCGACACGCTCGCGTCCATTACGAAAAGGCCTCGTTCGTCTGCGACATCTGTGGCAAGGGATTCCTGCGCAAGGACAAGTACACGTTCCATCTACGCTCGCACGAGAAGAGAGAGGCCAAGTGCCAGGCCCTCCAGCTGAAGAACGAGTGGAGATACGCGGAGCGTTTGTACAGCTCCGGGCGACTGAAGCGAATACAATGCAAATTGTGTGGCCTGAAATGCCAGCGAATGCAGGAGCTCCGATCCCATTTGTTGAGTCACACTCGCACGGATGGTTTGACCAGTCTGCGTGCGGACAGCGATGTGGTCAAGGAACATTTTGCCAGTGTGCCATTTGACCTGGAAAAGATCAAGCAGCGGGTCTGCACGGAAATAGCCGAAGGGCAGCTGGAAAAGTACTCGTGTGTGGTTAATTTCCACGGCTACGAGCTGTGCCTGAGCGACTCGGACGATGAGCCTGCCGGTGGAGAGCCACCGTATCGTTGTGACCCGTGCAATCAGTCGTACACGCGAAAATATCGCCTGATGCGTCACACACTGGAGGAGCACACCCAATCGCCCATTTCGCAGCGTTGCAACCTGTGCAAAGTTGGTTTCGTGTGTGCAAGGCTCTTTGAACAGCACCAGCGGACCCAGTGCCAGAGCAAAGTGAAACGCTATCGCTGCCGCAAGTGTCCGGGGAAGTTCATGTGGCTGGAGAATCTGGAGCGGCATGCCTGCTCCCATCGCAAGGAGGAGCAGTCGTACAGGCAAATCATTTGCTGCCTGTGCGATGCTCAACTGTACAGCTTGAGGCAGCTGCGCGCACACCTGGCCACCCATCGACATGGATTGAGTGGCATTGATCCGGAGCAGAAGTCCACCTTCTTTCGTTCCTACTATCCCAACGGATTGGGTTGCAGCCTTTCCGAGCTGAGCTCCCGCATAGCTGGGGACTATGAGGCCCAAGACTTTGGACGCTACTACAACGCCTGCACGGGAAGTGGTCAAGAGCTGGATATTTTTGACTCCGAAACAGAGGAGGGCGATGCGCACGAAACAGACGAAAAGCCGAAACTCTTGCACATCTGCCTGCTGTGTGGAGAGACTTCTATTCgtctgctccagctgctgcaacaTCAGAGGAGACTCCACTGCGCAGAGGACACCACGTATCCCTGCTCTTGCGAGGATTGTGGCGCTGGCTTCGTGTCCGATGCCTTGCTAGAGCAACATCGCAGACGATCCTGTGCTAAGAAGCACTCAAAATACCACTGCCAGCAATGCAATCTTCATTTTGTGTGGCAATCGAACTACGAGCAACATCTGCGATTGTACCACTCCAAGGATGAGGATCAGGAGCAGTCGGAGGACTGCCAGCAgggtagaaaatataaatcttCGCCCGTCAAGCTACAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTCACGCGACACAAGCGAATTCATCGCCATCCGTCGGCAGCCCAATACGAGTGTGCCCATTGCGACCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCCCACATGCGGGTGCAcaacgaacagcagcagcaggaggcggcTGTAAATGAGGAGCAGCCTTCTTCCGCCCAGTCGACATCTACAAACAGTATTCAGAGAATGACCGGGGAGCAGCTGACCCAACTATGCCGTCCAAATGGCTGCAAGCAAATCCAGTGCATGATTTGCCTCTCGCGCCACTCGAAGATCGCCGACTTGAGGACTCACCTCAGCGGGCACCAGTATGGAGCGGGCTTTCCACAGGACAGGGATATTGCCAGTGCCTCGCGCTCGCTGTATCCCGAACTGGGCACTGCCCTGGATAagcaggagctgctggagAGGATCATGAGCGATGTGGCAAGCGGCTTGGAGTTGGAGCGATTCATTTCCATAACCAACGAGGCTGGCATTGAGCTCTCGCTGGAGAGCAGTGAAACGGAAACGGATTCAGAGCAGGAGGATGACGAGAGTTCCGAGGAAgcggagcagcagcggtaCGCATGCAACATTTGCCAGCTGGAGGTAAAGCGGAAGCATCAGTTGTATGCCCACCAATTGGAGCAACACCAGTGGGAGGAGGCGTCGCTTGTGTGCGCCCACTGCCAGGCAAGATTCGTGAGTGAGGCGCTGCTGGCGCATCACTACCGGACACTCTGCCGGAATACCCAGAAGCGCTTCCAGTGCCGCAAATGTCCGCTACGCTTCCGCTGGCGGGAAAACCTAAAGCTGCACGTCAGTGCCTCCCATCAGCAAAGGGAACAAATCCAACCAGCTGTAGAGGAACCCAGCAGGAAGGCCGAGCTCGAGCTGCAGTGTGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTGACGCGGCACACGCTGATGCATGCCCAGGAATCGAGCATTTATCGCTGTCGTTGGTGTGCCCGCCGGTTCTACAGGAAGGCCAATCTCCTGCAGCACATTGAGCGGCACGGCATCGGAGCTAGCCAGCTGCCCTACGCGGAAGCTCTCCTCAATGCCTATGGCCATCCCAATGGGCAGAAGAGTGTGGAGTGCAAAGTGTGCAGCCTGAGCTTCTCCAGCATCGCTGCCCTTCGCGTTCATCTGGAGACCATGGCGTCGGGCAGTCACCACGAGCTGTCGTCTCACCAGAACTACTCGATAACCAACCATATGGGATTCGAGCTGCATTTGGATGACTCGGAGACGGATGAGGAGGACTCCAAACCACCGGGCACGCCTGCATCCTACACGTGTGGCATGTGCCAGCTGCGGTGTGTGCGAAAGTACGAGctgcatcagcaccagcaggcCATGCACAGGTTGGAGAAGATCCCCGATGGCTGCGATCGATGCATTTTCAAGAGCGTCTCCCCCGATATTATCGCGCACCACAAGCGGGTGCAGTGCCACAACCAGGAGAAGCAGTTCAACTGCGCCAAATGCGGCTACAAGTTCATGTGGGAGTccaatctgctgctgcacatgcagctgcagcatggAAAGGCCGAAGAACAGGAAGACCCACCCCTGGATGAGCCCGAGGAGCAGAAGACTGTGTGCCAGATCTTTCAGTGCGGCCTCTGCCCCAGGAAGTACAATCGCAAGGATCGGCTGACGGCTCATGTAAAGAAGTTCCACAACCCAGTGGCAGGAACCCCAAGCGTCATACGCGCACCCATCCGTCCAGCGTCGCCCAAGGAGCCGAAGCGCTTTCTTTGCGCCTTCTGTGGCAAGGCTGTGAGCTCCTCCTCGAACCTCATCATCCATATGCGACGTCACACGGGCGAGAAGCCCTTTAAGTGCGACTACTGCGAAATGGCCTTCCCGCGCTCCTCCGATCTTCAGTGCCATCGACGAACGCACACCGGCGAGCGGCCCCACATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCtacaaactgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACGCTCCACATCCGCCGCCACACCGGCGAGCGTCCGTATCAGTGTGGGGTATGCGGCGAGCGTTTTATCCAGGGCACGGCCCTCAAAAACCATCGACTGCAGCAAGGACACAATGACGAGGCCAGCCAGGGAGCTGCAAAGTCCTCAAGGCGCACGGTTCTAGAGCAATTTACAGTATAG
Protein Sequence
MLPSNICRTCALHKNNLLALSTSLDQYTNKSFYDVLQELTQIDPLLENADDNLPQHLCTDCLDRLKNAYAFVEQARKVNGELLMRLQECLEESPIDIPEEQIKTEIDIDEEQRDFSDSGEAQGLSDVDVESAGACSVEYKWTPESDSEDENADALSNDEDDDGDEQQQPYALRRSSRKVKPQADSEVEEQPPNKRRRGRPPGLAKSKSRNSEGRHACEVCGKTFSWFRDMKRHARVHYEKASFVCDICGKGFLRKDKYTFHLRSHEKREAKCQALQLKNEWRYAERLYSSGRLKRIQCKLCGLKCQRMQELRSHLLSHTRTDGLTSLRADSDVVKEHFASVPFDLEKIKQRVCTEIAEGQLEKYSCVVNFHGYELCLSDSDDEPAGGEPPYRCDPCNQSYTRKYRLMRHTLEEHTQSPISQRCNLCKVGFVCARLFEQHQRTQCQSKVKRYRCRKCPGKFMWLENLERHACSHRKEEQSYRQIICCLCDAQLYSLRQLRAHLATHRHGLSGIDPEQKSTFFRSYYPNGLGCSLSELSSRIAGDYEAQDFGRYYNACTGSGQELDIFDSETEEGDAHETDEKPKLLHICLLCGETSIRLLQLLQHQRRLHCAEDTTYPCSCEDCGAGFVSDALLEQHRRRSCAKKHSKYHCQQCNLHFVWQSNYEQHLRLYHSKDEDQEQSEDCQQGRKYKSSPVKLQCDECEKVFIWHKDLTRHKRIHRHPSAAQYECAHCDRKFHRKDGLKSHMRVHNEQQQQEAAVNEEQPSSAQSTSTNSIQRMTGEQLTQLCRPNGCKQIQCMICLSRHSKIADLRTHLSGHQYGAGFPQDRDIASASRSLYPELGTALDKQELLERIMSDVASGLELERFISITNEAGIELSLESSETETDSEQEDDESSEEAEQQRYACNICQLEVKRKHQLYAHQLEQHQWEEASLVCAHCQARFVSEALLAHHYRTLCRNTQKRFQCRKCPLRFRWRENLKLHVSASHQQREQIQPAVEEPSRKAELELQCGECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRKANLLQHIERHGIGASQLPYAEALLNAYGHPNGQKSVECKVCSLSFSSIAALRVHLETMASGSHHELSSHQNYSITNHMGFELHLDDSETDEEDSKPPGTPASYTCGMCQLRCVRKYELHQHQQAMHRLEKIPDGCDRCIFKSVSPDIIAHHKRVQCHNQEKQFNCAKCGYKFMWESNLLLHMQLQHGKAEEQEDPPLDEPEEQKTVCQIFQCGLCPRKYNRKDRLTAHVKKFHNPVAGTPSVIRAPIRPASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHNDEASQGAAKSSRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00471775;
90% Identity
iTF_00474640;
80% Identity
-