Csub026191.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Catotricha subobsoleta
Gene Symbol
Lztr1
Assembly
GCA_011634745.1
Location
JAABKK010000137.1:38600-42001[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 8.4e-15 2.6e-12 47.5 0.3 4 96 364 474 361 488 0.88
2 4 0.82 2.5e+02 2.5 0.1 76 108 492 524 486 526 0.89
3 4 2.9e-19 9e-17 61.9 0.0 8 106 584 684 578 688 0.86
4 4 4.2 1.3e+03 0.2 0.0 78 100 688 710 683 718 0.82

Sequence Information

Coding Sequence
ATGTCAGGAAACATGAAACAGCAGAAGGTAATTTTGCCATCATCGTGTACAGGTGAAAATTCTTTGAGCTTAGATTTCACACCTTTCGAAATAATTCTACAATGGAAACGAATGCTGGAATGTGATGAATTTGTTGGTgcaagacgAAGCAAACATACGGTTGTTTCCTATAAAGACGCAATTTACGTGTTTGGTGGAGATAATGGAAAAAGCatgttaaatgatttaattcgGTTTGATGTCAAAGACAAATCATGGGGTCGGGCATTTGCAACTGGTACACCGCCAGCATCCAGATATCATCATTCTGCTGTTGTACATGGAAGTTCTATGTTTGTATTTGGTGGTTATACGGGCGATATTCATTCTAATTCGAatttgacaaataaaaatgatttgtttgagtataaatttcaaaatggaCAATGGCTAGAATGGAAATTTGTTGGAAGAACACCCGTTGCTCGTAGTGCTCATGGTGCAGCTGTTTATGATAACAAACTTTGgATTTATGCTGGCTACGATGGAAATGCTCGACTAAATGACATGTGGACAATGTCACTAAATGGAGATATTCGTCAATGGGAAGAGATTGAACAGAATGGCGATCGTCCGCCAACATGTTGTAATTTTCCTGTTGCTGTTGCTCGTGATTGTATGTACGTGTTCTCTGGACAAAGCGGattacaaataacaaatgCACTGTTTGAATTTAACTTCAAATCAAAGACgtGGCGCCGTATTTCAAACGAACATATTTTACGTGGAGCGCCTGCACCACCAGCAAGACGTTATGGACATACGATGGTACATCACGATAGATTTCTATATGTATTTGGTGGTTCTGCTGACAACACTCTACCAAATGATCTTCATTGCTATGATCTAGATTCACAAGTTTGGTCAATTGTCATTCCGGAAGCAGAATCCGAAATACCAACAGGAAGAGTATTTCATGCATCTGCTGTTATTAATGATGCcatgtatatttttggaggcacTGTTGATAATAATGTTCGAAGTGGCGATATGTTTCGCTttcaaTTCCCCAGTTATCCACGATGCACTTTACATGAtgattttggtaaatttttagTCGAACGTCAATTTTGTGATGTTCAATTTTTGGTTGGATTAGATGAAGTTAAAATTCCAGCACATATTGCAATTGTTGCGGCACGGTCGCAATTCCTACGAGCAAGAATCttGTCTGCCCGTGAAACACGAAATCAACATTTGGAAAAACTTTTTGGAACAATTGACGTTCCATTTACAGATCGACCAATTCTTGAAGTGAAACTTGCAGATGCGGTACCAGAAGCATTTGAAATGgttctaaattatatttataccgaTCGCATTGACTTTACggatcaaaaatcaaaaatagttttgctAATGATGGACATTTACCAGTTGGCTGCTCAATATTTGATACCACGTTTAGAACAAGTCTCCATTCAATacttagaatttaaaatatcgaaaagtAATGTTTTGGATGCACTCTACTATGCtgataaaatgaaaTTATCCCTCATCAAAGACTATTGTCTTAGCTTTATTGTAAAAGAAGATAATTTCTATGAGATTGTAATGTCAAATGTATTTGTTAATTTGGACAAACCATTGATGGTGGAGATTATACGAAAACGTTTAAATCCAGGTAGAAATACggatataaaatttgataaaactgcaggAACAACACTGGAAAATGatatgtcaatatttttaaaaactggtGGTAAAGAATTTTGTGATATTAATTTGATCTTAGACGAACATGTCATTCCAGctcataaatcaattttatcggCAAGATGTTCATATTTTCAAGCAATGTTTCGTTCATTTATGCCACCCGATAATACTGTCAACaTTCAAATTGGTGACATATCACCATCACAGGAAGCGTTTAACTCACTATTGCGATACATTTACTATGGCGATACAAAAATGCCACCAGAAGATTCATTATACTTATTTCAAGCACCATGTTTTTatgGTTTCACAAATAATCGTTTACAAGCATTTTGTAAACATAATCTTGAGCATAATATTCAcgttcaaaatgttttacaaattttagaaGCTTCCGATAAAATGAATGTGccagatattaaaaattatgctcTCAGTATGATTGTTCGAGATTTCTCACAAGTAGCACGTTTACCACGAATGCAAAATTTAAGCAGAGATTTACTATTGGAAGTGATTGAAGCAATGGCTGATGTTTTAGGCGAAATACGTTTTAGTCAGGATTTGACATCGATCAGTATTCATAGcgatatatga
Protein Sequence
MSGNMKQQKVILPSSCTGENSLSLDFTPFEIILQWKRMLECDEFVGARRSKHTVVSYKDAIYVFGGDNGKSMLNDLIRFDVKDKSWGRAFATGTPPASRYHHSAVVHGSSMFVFGGYTGDIHSNSNLTNKNDLFEYKFQNGQWLEWKFVGRTPVARSAHGAAVYDNKLWIYAGYDGNARLNDMWTMSLNGDIRQWEEIEQNGDRPPTCCNFPVAVARDCMYVFSGQSGLQITNALFEFNFKSKTWRRISNEHILRGAPAPPARRYGHTMVHHDRFLYVFGGSADNTLPNDLHCYDLDSQVWSIVIPEAESEIPTGRVFHASAVINDAMYIFGGTVDNNVRSGDMFRFQFPSYPRCTLHDDFGKFLVERQFCDVQFLVGLDEVKIPAHIAIVAARSQFLRARILSARETRNQHLEKLFGTIDVPFTDRPILEVKLADAVPEAFEMVLNYIYTDRIDFTDQKSKIVLLMMDIYQLAAQYLIPRLEQVSIQYLEFKISKSNVLDALYYADKMKLSLIKDYCLSFIVKEDNFYEIVMSNVFVNLDKPLMVEIIRKRLNPGRNTDIKFDKTAGTTLENDMSIFLKTGGKEFCDINLILDEHVIPAHKSILSARCSYFQAMFRSFMPPDNTVNIQIGDISPSQEAFNSLLRYIYYGDTKMPPEDSLYLFQAPCFYGFTNNRLQAFCKHNLEHNIHVQNVLQILEASDKMNVPDIKNYALSMIVRDFSQVARLPRMQNLSRDLLLEVIEAMADVLGEIRFSQDLTSISIHSDI