Wsmi034941.1
Basic Information
- Insect
- Wyeomyia smithii
- Gene Symbol
- Lztr1
- Assembly
- GCA_029784165.1
- Location
- CM056645.1:263085608-263088236[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 3.4e-14 2.7e-11 45.3 1.0 2 107 367 497 366 500 0.85 2 4 0.75 5.9e+02 2.4 0.0 76 108 498 530 495 532 0.89 3 4 1.9e-20 1.5e-17 65.5 0.0 8 105 591 690 585 695 0.85 4 4 2.1 1.7e+03 0.9 0.0 77 101 694 718 689 726 0.82
Sequence Information
- Coding Sequence
- ATGACCAGCACAAGTCGCTTCACATCGCCCACGCCTTCGACAGGGGTGAGCACACCGTGCACAAGTGGCACAGCCGCCGCAACCCCGATGGGACCGATTCCCAGTGCAGCGAACAAATGGAAGCGGATGCTAGAGTGCGATGAATTTGTGGGAGCTCGGCGGTCCAAGCATACGGTGGTCGCCTACAAGGACGCGATCTACGTTTTCGGTGGTGATAATGGCAAGATAATGTTGAATGATCTGATCCGTTTCGGCGTGAAGGATAAATCTTGGGGCAGAGCATTTTCGACGGGAACACCTCCGGCACCGCGCTATCATCATTCGGCTGTTGTGCATGGTACTTCAATGTTTGTGTTCGGTGGCTATACGGGCGATATTCATTCGAATTCCAACTTGACGAATAAAAACGATCTGTTTGAGTATAACTTCCAAAATGGACAGTGGACGGAGTGGAAGTTTGTCGGTAGAACGCCGGTTCCACGCAGTGCACATGGAGCTGCAGTTTACGAGAATAAACTTTGGATTTACGCCGGTTACGATGGTAATGCCCGACTGAATGATATGTGGACGATTCGTTTGACGGGAGATACACACCAATGGGAGGAAGTTCAACAGAAGGGAGAGCGACCTCCGACTTGTTGCAATTTTCCAGTTGCCGTCGCACGCGACTGTATGTACGTGTTTTCCGGCCAAAGTGGACTCCAAATCACTAACACGTTGTTTCAGTTTAATTTCAAAGACAAAACTTGGCGTCGTATATCTAACGAGCACATCCTGCGGGGAGCACCACCTCCGCCGGCCCGTCGATATGGCCACACGATGGTTCATCACGATCGCTTTCTGTACGTGTTCGGAGGTGCGGCCGACTCCACTCTGCCCAACGATTTGCATTGCTACGATCTGGACTCGCAGGTTTGGTCTACGGTGATTCCAGCACCGGAATCGCAGGTCCCTAGTGGTCGTCTCTTCCATGCAGCCGCCGTAATCGGCGATGCCATGTACATTTTCGGCGGAACCATAGATAACAACGTACGCAGCGGAGACATGTACCGATTTCAGTTCTCCAGCTATCCGAAGTGTACCCTGCAGGATGATTTCGGAAAGTTTCTGCAGAACCGACAGTTCTGTGACGTGCAGTTTGTTGTCGGTAGCGACGAGGTGCGGGTAGCAGCTCACATCGCCATGATTGTCGCGAGGTCACAGTTTTTGAGATCTAAAATATTAGCGGCTCGTGACGCGCGAAATGTTCATTTCGAAAAACTGTTCGGAACTACCGAGGTTCCATTCGCCGAACGGCCAGTTCTCGAAGTTCAGCTGCCAAACGCACAACCAGAAGCATTTGAGATGGTTTTAAACTATATTTACACTGATCGCATCGACTTTAAAGacccattttgtaacaaaattgtGCTACTAATGATGGACGTCTACCAGCTGGCGGTCCAATTCTACATTCCACGCCTGGAGCAGCTCTGCGTGCAGTACCTGGagtttaaaatatcaaaaaccaACGTCTTGGACGCATTGTACAATGCAGATCGAATGGGTCTGACGCTAATTAAGGATCACTGTCTCGGTTTTATCACAAAAGAGGATCACTTCTACGACATTGTGATGTCACCGGAATTTGCAGCCCTCGAAAAGCCGCTAATAGTAGAAATTATTCGCAAACGCCTGAACCCAAGCAAACATTCGACCGATATGAAGTACGACAAAACAATCGGAACTTCACTGGAGAATGACATGGCCGTGTTTCTGAAGTCCGGCGGAAAAGAGTTCTGCGACATTAATCTAGTGCTAGAGGGAAAAGTAATACCCGCTCATAAATCAATCCTAGCGGCCCGCTGTACGTATTTCCAGGCCATGTTTCGGTCTTTCATGCCAGCCGATAACACTGTTAACATTCAAATCGGTGACATTTCACCGTCCCAAGAGTCGTTCAGTTCGCTGCTGCGGTACATTTACTACGGTGACACCAAAATGCCCCCGGAGGATTCGCTGTATCTTTTTCAGGCCCCCTGCTTTTACGGATTCACCAACAATCGGCTGCAGGCGTTCTGCAAGCACAACCTTGAAAACAACATCACCTACGACAACGTCCTGCAGATCCTGGAGGCGTCGGACAAAATGAACGTTCCGGACATCAAGAACTATGCGCTGCGCATGGTGGTGCACAACTTTTCCCAGGTCGCCCGACTACCGAAGATGCAGGAACTGACCCGGGAACTGCTGCTAGATGTCATTATGGCCGTAGCGGACGCGAAGGGCGACGGCAGCAAACGCATCAGCCACGATTCCACCTTCATCAGTCTGTACAGTGACATCTGA
- Protein Sequence
- MTSTSRFTSPTPSTGVSTPCTSGTAAATPMGPIPSAANKWKRMLECDEFVGARRSKHTVVAYKDAIYVFGGDNGKIMLNDLIRFGVKDKSWGRAFSTGTPPAPRYHHSAVVHGTSMFVFGGYTGDIHSNSNLTNKNDLFEYNFQNGQWTEWKFVGRTPVPRSAHGAAVYENKLWIYAGYDGNARLNDMWTIRLTGDTHQWEEVQQKGERPPTCCNFPVAVARDCMYVFSGQSGLQITNTLFQFNFKDKTWRRISNEHILRGAPPPPARRYGHTMVHHDRFLYVFGGAADSTLPNDLHCYDLDSQVWSTVIPAPESQVPSGRLFHAAAVIGDAMYIFGGTIDNNVRSGDMYRFQFSSYPKCTLQDDFGKFLQNRQFCDVQFVVGSDEVRVAAHIAMIVARSQFLRSKILAARDARNVHFEKLFGTTEVPFAERPVLEVQLPNAQPEAFEMVLNYIYTDRIDFKDPFCNKIVLLMMDVYQLAVQFYIPRLEQLCVQYLEFKISKTNVLDALYNADRMGLTLIKDHCLGFITKEDHFYDIVMSPEFAALEKPLIVEIIRKRLNPSKHSTDMKYDKTIGTSLENDMAVFLKSGGKEFCDINLVLEGKVIPAHKSILAARCTYFQAMFRSFMPADNTVNIQIGDISPSQESFSSLLRYIYYGDTKMPPEDSLYLFQAPCFYGFTNNRLQAFCKHNLENNITYDNVLQILEASDKMNVPDIKNYALRMVVHNFSQVARLPKMQELTRELLLDVIMAVADAKGDGSKRISHDSTFISLYSDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00285557;
- 90% Identity
- iTF_01462082;
- 80% Identity
- -