Aepi002416.1
Basic Information
- Insect
- Anopheles epiroticus
- Gene Symbol
- Lztr1
- Assembly
- GCA_000349105.1
- Location
- KB671558:141823-144626[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 4.3e-15 8.2e-13 47.9 0.5 2 107 363 493 362 496 0.84 2 4 3.7 7.1e+02 -0.2 0.0 76 107 494 525 491 527 0.87 3 4 1.3e-20 2.4e-18 65.7 0.0 8 106 587 687 581 691 0.85 4 4 7.8 1.5e+03 -1.2 0.0 77 100 690 713 681 722 0.76
Sequence Information
- Coding Sequence
- ATGTCCACCGGACGCTTCGTGTCGTCCGCGTCGATCGGCAGCACCAGCACCTCCTCCAGCACGCAAATATCGGCCAATGTTCCCATCTCCAATACGGCCAACAAGTGGAAGCGTGAGAGCGATTGTGATGAGTTTGTTGGCGCTCGCCGTTCGAAGCACACGGTCGTGGCCTACAAGGAAGCAATCTACGTTTTCGGTGGGGACAATGGCAAAAATATGCTGAACGATTTGATTCGCTTCGGTGTGAAGGACAAATCATGGGGCAGGGCGTTTGCTACCGGAACACCTCCAGCGCCGCGCTATCACCATTCGGCTGTCGTGCACGGAACATCAATGTTTGTGTTCGGAGGTTACACGGGCGATATACACTCGAACTCGAATCTCACCAACAAGAACGATCTGTTTGAGTATAACTTCCAGAATGGGCAGTGGACGGAGTGGAAGTTTATTGGCCGTACGCCGGTGGCAAGAAGTGCTCACGGTGCCGCCGTGTACGACGGTAAGCTGTGGATCTACGCGGGCTATGATGGAAATGCCCGTTTGAATGATATGTGGACTATTCGGTTAACGGGTGAAACACATCAATGGGAAGAGGTGGAACAGAAGGGTGACCGTCCGCCAACATGCTGCAACTTTCCTGTTGCTGTAGCCCGTGGCTGTATGTACGTGTTTTCCGGACAAAGTGGACTACAAATTACCAACACACTGTTTCAATTTAACTTTAAAGACAAAACTTGGAGAAGAATATCGACGGAACACATTCTTCGCGGTGCTCCACCACCGCCAGCTCGACGGTACGGTCATACGATGGTACATCACGATCGCTTCTTGTACGTGTTTGGTGGGGCGGCCGATTCAACGCTCCCGAACGATCTGCACTGCTATGATCTGGATAGCCAGATATGGTCCACCGTAACTCCTGCACCGGAATCACAGATCCCCAGCGGACGGTTGTTCCATGCGGCCGCTGTAATTGGGGATGCAATGTACATCTTCGGCGGAACGATCGATAACAATGTGCGCAGTGGTGACACGTATCGGTTTCAGTTCTCGAGCTATCCAAAGTGCACGCTGCATGATGACTTTGGCAAGTTTCTACAGAATCGTCAGTTTTGTGACGTTCAATTCATTGTGGGGACGGAGGAGGTAAAAATTTCCGCCCACATTGCCATGATAGTGGCTAGGTCGCAGTTTTTACGATCGAAAATTTTAGCTGCACGGGATGCGAGGAATGTACACTTTGAAAAGCTGTTTGGGACGACCGATGTGCGACTTGCAGAGCAACCAATACTGGAGGTTCAACTGCCGGACGCTCAACCGGAGGCGTTCGAGATAGTGCTAAACTATATTTACACTGATCGGATTGTATTTAAGGACCCATTCAGCCACAAGCTCGTGCTGATCATGATGGACGTGTACCAGCTTGCGGTACAGTTTAACATTCCCCGTTTGGAGCAGCTTTGCGTGCAGTATTTGGAGTTTAAAATTTCGAAATCGAATGTGCTCGATGCACTATACAATGCCGATCGGATGGGACTGACGCTCATCAAGGACTACTGTCTCGGGTTCATCGTGAAGGAAGACCATTTTTACAACATCGTAATGTCGGCCGAGTTTGCCGCCCTAGATAAACCGCTGATCGTTGAGATCATTCGCAAACGGCTTAACCCGAGTAAACATACCACGGACATGAAGTACGACAAAACGATAGGCACCACGTTGGAGAGTGACATGGCAGTGTTTCTAAAATCGGGTGGGAAGGAATTCTGCGATATTAATCTGGTTCTCGAAGAGAAGATCATACCCGCACACAAGTCCATTCTTGCCGCCCGTTGCACCTACTTCCAGGCAATGTTCCGTTCGTTCATGCCGGCCGACAACACGGTCAACATACAGATTGGGGATATTTCTCCTTCGCTCGAAGCGTTCGATTCACTGCTTCGCTACATCTACTACGGTGATACCAAGATGCCACCCGAGGATTCACTGTATCTGTTTCAAGCGCCTTGCTTCTACGGGTTCGCCAACAATCGGCTGCAGGCGTTCTGTAAGCACAACCTAGAAAATAACATAACGTACGATAATGTGCTGCAGATACTGGAAGCTTCGGACAAGATGAACGTACTTGACATTAAAAACTATGCGCTCAAGATGGTCGTGCACAACTTTAGCCAGGTAGCGAAGCTACCGAAAATGCAGGATCTATCACGGGAACTGCTACTCGACGTGATAATGGCCATCGCGGATATGAAGGTGGAAAACAAGCAGCGAATCCACGACACATTCATTAGCCAGTACAACGATATTTGA
- Protein Sequence
- MSTGRFVSSASIGSTSTSSSTQISANVPISNTANKWKRESDCDEFVGARRSKHTVVAYKEAIYVFGGDNGKNMLNDLIRFGVKDKSWGRAFATGTPPAPRYHHSAVVHGTSMFVFGGYTGDIHSNSNLTNKNDLFEYNFQNGQWTEWKFIGRTPVARSAHGAAVYDGKLWIYAGYDGNARLNDMWTIRLTGETHQWEEVEQKGDRPPTCCNFPVAVARGCMYVFSGQSGLQITNTLFQFNFKDKTWRRISTEHILRGAPPPPARRYGHTMVHHDRFLYVFGGAADSTLPNDLHCYDLDSQIWSTVTPAPESQIPSGRLFHAAAVIGDAMYIFGGTIDNNVRSGDTYRFQFSSYPKCTLHDDFGKFLQNRQFCDVQFIVGTEEVKISAHIAMIVARSQFLRSKILAARDARNVHFEKLFGTTDVRLAEQPILEVQLPDAQPEAFEIVLNYIYTDRIVFKDPFSHKLVLIMMDVYQLAVQFNIPRLEQLCVQYLEFKISKSNVLDALYNADRMGLTLIKDYCLGFIVKEDHFYNIVMSAEFAALDKPLIVEIIRKRLNPSKHTTDMKYDKTIGTTLESDMAVFLKSGGKEFCDINLVLEEKIIPAHKSILAARCTYFQAMFRSFMPADNTVNIQIGDISPSLEAFDSLLRYIYYGDTKMPPEDSLYLFQAPCFYGFANNRLQAFCKHNLENNITYDNVLQILEASDKMNVLDIKNYALKMVVHNFSQVAKLPKMQDLSRELLLDVIMAIADMKVENKQRIHDTFISQYNDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00285557;
- 90% Identity
- iTF_00105891;
- 80% Identity
- -