Bhor008139.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus hortorum
Gene Symbol
gtf3a
Assembly
GCA_905332935.1
Location
HG995190.1:6163775-6168099[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 5.5e-07 5.8e-05 23.6 0.3 2 23 723 744 722 744 0.97
2 17 7.2 7.7e+02 1.2 1.4 1 19 750 768 750 769 0.91
3 17 4.2 4.4e+02 1.9 2.2 1 23 776 798 776 798 0.94
4 17 0.00022 0.024 15.4 1.2 3 23 807 828 806 828 0.98
5 17 0.0023 0.24 12.2 2.0 1 23 835 858 835 858 0.95
6 17 8e-05 0.0086 16.8 0.7 1 23 864 887 864 887 0.94
7 17 1.1 1.2e+02 3.7 2.5 2 23 895 915 895 915 0.94
8 17 1.2e-07 1.3e-05 25.7 2.1 2 23 921 942 920 942 0.97
9 17 1.9e-06 0.0002 21.9 0.2 1 23 948 970 948 970 0.99
10 17 0.00047 0.05 14.3 2.4 2 23 982 1004 981 1004 0.95
11 17 0.0067 0.71 10.7 2.5 1 23 1010 1033 1010 1033 0.96
12 17 0.021 2.3 9.1 3.8 3 23 1055 1076 1054 1076 0.95
13 17 0.00099 0.11 13.3 1.4 2 23 1083 1105 1082 1105 0.96
14 17 0.0001 0.011 16.4 1.6 2 23 1113 1134 1112 1134 0.96
15 17 0.001 0.11 13.3 2.3 1 23 1140 1163 1140 1163 0.96
16 17 0.28 29 5.6 3.2 2 23 1170 1191 1169 1191 0.96
17 17 0.0081 0.86 10.5 2.6 1 23 1197 1219 1197 1219 0.98

Sequence Information

Coding Sequence
ATGCAGCACACTGAAGTTAAAAACAAGGATCATAATTATAGTGAAGTAAAATTACATAGTATTCAGCATACTGCTAGTAATATCCTTAATGTATGTGATAGTGATGTTAAAACAACATGTAAATCAAACAAAACTGGATTAGTATCGAATAAAGAAATATTCGGTCAGATTAAAGATATTAGTGAATTAAAAAAAATTACACCACGTGTAAAATTGTTGACTCATGATGCAAATAGTTTAAATGAATTAACTAAAATTTCTTTGCACAATAAAGTATCTGTGCAAAAGAAACTATCAATATCAGAACAAACAAAACAGGAATTAAAAAAGTATTGTAGGACTTGTGCTGGTTTGAAACTTCCATTAGTTGATATTTTTAGTGAAAAAGGTAATCAAATGAGATTAAGTCAACAAATTAAGCATTTAGAAGAAATAAATCCATACGATAGTTTATCAACTCAAATGTGTATGGATTGTATCTGTGACTTAAAAATGAGTTATAAGTTTTTTATGCAAATTAAAAAAGCAGAAGTTAAATTAAGATCTATTCACATTACTCTCACAGATACAGCGACAAAAAATGCAGAATTAAATAAAATGCAGCCTGTAGGAAGTTTCGAGAAACAGATGGAAAATGCTGTTGAGTATAATACAAAAAATCCATCTACAAGTAAAGAATATACTTCTGTACCAAAAATATCTGCAATTTTTTCATTAAAAGATAATGAAGATATTGTAAAAGATAAGAAACTTTGTACAGATCATAAAGAATCAGAAAGTAAAGTTGAACCTGGAATTTTTGAAGACACCACTGTCTTACAAAATAGTGATGATAATGAATCAATAGAAGAATTTGATCCAGATGATCCTCCTTTTCAACCTGATAGTTCTGATGTTGCAGAGTCTGATGATGAAGTAGAAATACCAAGTGCAAAAAGACGACATATTCAACAGAAAGAAAATACAAAACAATGTTCACAATCAACTATTGTTCCTGATAATAATCCAATTTCAGATAATAAAAGTACTGAAATTAACCAAACAACGTATAATTATGAATGTATGAGAACATACATTAAAGTAGGGGACACAGAATGTAATAATACTGAACCACGCAGCGTCAATAATTCTGAAAGTACAAAAGAATGTTCAAAACAACCAAACATATTAAAACGCAGGTTATTATTACAGTCTAAAAAAGAATCTACAGAAGAAACTGATGAAAATATTTACCAGACAAATATTTCTGATAAAAGCCATAAAGACTTAAAAGTACAAAAACTCGATGTAAACAATTCTTTGAACCTTAACAGTAATCAAGAAGATGGCATCATGTATGTTACTGTGAAAGGATCTAAACCGAATGAAATATTGTTAGTAAAAGTTAAGAAAATGGATAAACCATTAGAGAAAAAAGAAGATAAATCTACAGGGAAAAAGAATTTTGACATTAAACCAATGGATAAGATTTTAAAACGATATGAAACATTAGTTACAAAAGAAAAAGATTTATTTCCAGAACGAACAAAAAAGTTAGAAATAAGAGAGCAGATTATAGAGGAACAAATAGAAGAATACAAAAAAAAGCGAGAAAAAGTATTAGGTGGACACGCCAATATTGTTGCACCTCCAAAATTTGAGGAATCTCGTTACTTTAAGCGTAATGAAAGTCAAGATAATCAAAGATCTTTTACACATATAGAAAATGATTCTGCTGTAAACATACAGTTTAATAAAGATGATAGTGAATTTAATGCAACTATTACAATTGAAGATGATGCTATAGAAATTGCAGAATCAGCCAAAGAAAAGTCTACAAATGAAAAAGCATATGTAAATACTGAAGAATATTTATCACGTTTAGCAAAGCTTAAATTGAAATGGGAAGAAGCAAAAAAGAAGAAAGAATATCTTCAAAAAGAACTTGATGAATCTTATACAGAAGGAAATATTGAAAAGTTAGCAAGAATTTTAGGGGAAAAAAAAAAAAATTTGCAGGACTTTCAAGATTATTTAAAACAACGTAAAATTGTAATTACAAGATTAAAAGATGAGGATATTATTTCTCTTTATGAAGACAGAAATAATGCAGTCCTTAAAAACAACTTACCTGACTTAATAGATGAAAGTCAACCAGCAGATTATATTCCAGAAGAACATTATTTAGAATGTGATTATTGTCCAAAAACATTTGCTTCTAAAGAAACTCTTGAAGAACATTTAAGAACACATGACTATAAAATTATGCATTTTTGTGAAGATTGCATGCAAGAATTTTCAACAAATAAAGCAAAACGAAATCATAATGTGAATTGCATAGAAAAATTCAAGTGTAAACAGTGTAACATGTTGTTAGGTTCAAAAGGAAAAAAGCGTCAGCATGAACAGAAACATAGTGATGATAATTATGGACAATTATGCGATGTATGTGGTGAAAAGTTTAAACATCAAGGAACATTGGATCAACATGTCAAAACACAACACATGAATTGGGAGAAAATATATCAATGTCCAAAGTGTCCTAAAAAGTTTGCATTCAAACAAAAACTTAGCTTTCATTTGAAATCTGTACACACAACTTTAAGAGCCTATTTGTGTGAGGACTGTGGAGCTGATTTTAAAAATCCTGCAAGTCTTAGACATCATAGAATACGTAAACATCAACCTGTAAGTAATAAGAGAGAATGCCCAGTTTGCCATAAATTAGTACCATTTTATAGCCTTTCTAAACACATGCATACTCATAAAGCATATACTATTCAGTGTCCACACTGTGACAAAATGTTTAAAAATAGTTCAACTTTAAAGCAACATGTAAGAATTCATGAAGATCAACGTCAATATCGATGTGATACTTGTGGTGTTGGATTTAATAGAAGAGATGGTTTAAGGTTACACATGAGAGTACATGAGAAGACCGATAGTAGAGGATTAAAAGAATGTTCATGTCAAGTATGTGGTGAAAAGTTCCCAAATCATTCAACACTTGTTATACATAGGAACCGAGTTCATAAGGATGGTAGACAATACACTTGTCATATATGTAATAGATCAATGATTTCAACTAGATCATTAGAGTGGCATATGTCTCATATACACAATGAAACGCTTCCTGGTGTAAAGGAAGGGATAGATGGGGCACCAGAAAAAAGAAGGGCATCATGTTATCATTGTAATAAGACATTCAAAACAGAAATGATTTTGAGAACGCATATTAAAAACACACATATGGAGAAAGATCCTATGAAATGTTTAGATTGTGAATTAACATTTACTTCCGAAGTGAGGTTAAGACATCATATGATGGTCACACATAACAGATTAGAAGGAACTTTACCATGCCCACATTGTTCAAAGAGATTTGTGAATCAACTCAGATTAAAAACTCATATGATATCTCATTCTGAAGAAAGGCCATACACTTGTGAAATCTGTGGGTTTAATTTGAAAACTAAGATACAGTTGATTAAACATCATCAAAATAGGCACAGCGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCACTTGTATGTCATGAAAGAACTCATACAAATGAACGACCATATTCTTGCAGTGTATGTAGGCAACGTTTTAAATATTTAGGTGATAAAAATAAACATGAAAGACGACATGAAAGCTTAGGAGGATCTGGATTTAAAAGGATAATACTTAGTCGAAATAGTAAACCTAAACCATTAGAAGATTCTTCTTGTTCTGAACACGAAAGTTTAAATAATATAAAGTGTCAAGTTCCTGAAAGTGAATATCAAGAACAGACAGATCAACAATTTGAAGAAGAACAAATAATTAAATTTGAAGAACAAGAAATAACAGAAGAATATGAACAAGTATATGAACAGGAATATGAAGAGACATCCAGAGAAGCTTCTGATGCAGCAGAAGTTATAATGAATATGGAAGATACAACAGTTTACACAGAAGAAGTAACTGCAGATAACATTGAACCTACAGAAATTATGGCAGATGAAATAATGACAAATGAAATATTACAATCAGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGGAAAATACAAGTGATTCCAGTGATGTTATCTTTACCTGATTTATCCGATGCAAATACAGAGGTCAATTTAGCTACTGCATCCATTATGTATAATAATTGA
Protein Sequence
MQHTEVKNKDHNYSEVKLHSIQHTASNILNVCDSDVKTTCKSNKTGLVSNKEIFGQIKDISELKKITPRVKLLTHDANSLNELTKISLHNKVSVQKKLSISEQTKQELKKYCRTCAGLKLPLVDIFSEKGNQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLRSIHITLTDTATKNAELNKMQPVGSFEKQMENAVEYNTKNPSTSKEYTSVPKISAIFSLKDNEDIVKDKKLCTDHKESESKVEPGIFEDTTVLQNSDDNESIEEFDPDDPPFQPDSSDVAESDDEVEIPSAKRRHIQQKENTKQCSQSTIVPDNNPISDNKSTEINQTTYNYECMRTYIKVGDTECNNTEPRSVNNSESTKECSKQPNILKRRLLLQSKKESTEETDENIYQTNISDKSHKDLKVQKLDVNNSLNLNSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKEDKSTGKKNFDIKPMDKILKRYETLVTKEKDLFPERTKKLEIREQIIEEQIEEYKKKREKVLGGHANIVAPPKFEESRYFKRNESQDNQRSFTHIENDSAVNIQFNKDDSEFNATITIEDDAIEIAESAKEKSTNEKAYVNTEEYLSRLAKLKLKWEEAKKKKEYLQKELDESYTEGNIEKLARILGEKKKNLQDFQDYLKQRKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPKTFASKETLEEHLRTHDYKIMHFCEDCMQEFSTNKAKRNHNVNCIEKFKCKQCNMLLGSKGKKRQHEQKHSDDNYGQLCDVCGEKFKHQGTLDQHVKTQHMNWEKIYQCPKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVSNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNETLPGVKEGIDGAPEKRRASCYHCNKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFTSEVRLRHHMMVTHNRLEGTLPCPHCSKRFVNQLRLKTHMISHSEERPYTCEICGFNLKTKIQLIKHHQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIILSRNSKPKPLEDSSCSEHESLNNIKCQVPESEYQEQTDQQFEEEQIIKFEEQEITEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPTEIMADEIMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLSDANTEVNLATASIMYNN