Basic Information

Insect: Bombus vosnesenskii
Gene Symbol: gtf3a
Assembly: GCA_011952255.1
Location: NW:290299-296220[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 4.8e-05 0.0031 17.2 0.1 2 23 730 751 729 751 0.97

2 16 0.62 40 4.2 1.5 3 23 785 805 784 805 0.97

3 16 0.00018 0.012 15.3 1.2 3 23 814 835 813 835 0.98

4 16 0.0075 0.49 10.2 2.9 1 23 842 865 842 865 0.95

5 16 6.6e-05 0.0043 16.7 0.7 1 23 871 894 871 894 0.94

6 16 0.9 58 3.7 2.5 2 23 902 922 902 922 0.94

7 16 9.6e-08 6.2e-06 25.6 2.1 2 23 928 949 927 949 0.97

8 16 1.5e-06 0.0001 21.8 0.2 1 23 955 977 955 977 0.99

9 16 0.00039 0.025 14.3 2.4 2 23 989 1011 988 1011 0.95

10 16 0.0055 0.35 10.7 2.5 1 23 1017 1040 1017 1040 0.96

11 16 0.092 5.9 6.8 2.2 3 23 1062 1083 1061 1083 0.94

12 16 0.0021 0.13 12.0 0.9 2 23 1090 1112 1089 1112 0.96

13 16 9.5e-05 0.0062 16.2 0.6 2 23 1120 1141 1119 1141 0.95

14 16 0.0009 0.058 13.1 2.5 1 23 1147 1170 1147 1170 0.96

15 16 0.23 15 5.6 3.2 2 23 1177 1198 1176 1198 0.96

16 16 0.0066 0.43 10.4 2.6 1 23 1204 1226 1204 1226 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	4.8e-05	0.0031	17.2	0.1	2	23	730	751	729	751	0.97
2	16	0.62	40	4.2	1.5	3	23	785	805	784	805	0.97
3	16	0.00018	0.012	15.3	1.2	3	23	814	835	813	835	0.98
4	16	0.0075	0.49	10.2	2.9	1	23	842	865	842	865	0.95
5	16	6.6e-05	0.0043	16.7	0.7	1	23	871	894	871	894	0.94
6	16	0.9	58	3.7	2.5	2	23	902	922	902	922	0.94
7	16	9.6e-08	6.2e-06	25.6	2.1	2	23	928	949	927	949	0.97
8	16	1.5e-06	0.0001	21.8	0.2	1	23	955	977	955	977	0.99
9	16	0.00039	0.025	14.3	2.4	2	23	989	1011	988	1011	0.95
10	16	0.0055	0.35	10.7	2.5	1	23	1017	1040	1017	1040	0.96
11	16	0.092	5.9	6.8	2.2	3	23	1062	1083	1061	1083	0.94
12	16	0.0021	0.13	12.0	0.9	2	23	1090	1112	1089	1112	0.96
13	16	9.5e-05	0.0062	16.2	0.6	2	23	1120	1141	1119	1141	0.95
14	16	0.0009	0.058	13.1	2.5	1	23	1147	1170	1147	1170	0.96
15	16	0.23	15	5.6	3.2	2	23	1177	1198	1176	1198	0.96
16	16	0.0066	0.43	10.4	2.6	1	23	1204	1226	1204	1226	0.98

Sequence Information

Coding Sequence: ATGAATAGGTCAAAGATGCAGCACACTGAAGTTAAAAACAAGGATCATAATTATAGTGAAGTAAAATTACATAGTATTCAGCATACTGCTAGTAATATCCTAAATGTATGTGACAGTGATGTTAAAACAACATGTAAATCAAACAAAACTGGATTAGTatcgaataaagaaatattcggtcagattaaagatattaatgaattaaaaaaaattacaccACGTGTAAAATTGTTGACTCATGATGCAAATAGTTTAAATGaattaactaaaatttctTTGCACAATAAAATATCTACGCAAAAGAAACTATCAATATCAGAACAAACAAAACAggaattaaaaaagtattGTAGGACTTGTGCCGGTTTGAAACTTCCATTAGTTGATATTTTTAGTGAAAAAGGTAATCAAATGAGATTAAGTCAACAAATTAAGCAtttagaagaaataaatcCATATGATAGTTTATCAACTCAAATGTGTATGGATTGTATCTGTGACTTAAAAATGAGTTATAAgttttttatgcaaattaaaaaagcaGAAGTTAAATTAAGATCTATTCACATTACTCTCACAGATACAGCGACAAAAAATgcagaattaaataaaatgcagCCTGTAGAAAGTTTCGAAAAACAGATGGAAAATGCTGTTGAGtgtaatacaaaaaatccATCTACAAGTAAAGAATATACTTCCGTACCAAAaatatctacaattttttcattaaaagatAATGAAGATATTGTAAAAGATAAGAAGCTTTGTACAGATTATAAAGAATCAGAAAGTAAGGTTGAACCTGGAATTTTTGAAGACACCACTGTCTTACAAAATAGTGATGATAATGAATCAATAGAAGAATTTGATCCAGATGATCCTCCTTTTCAACCTGATAGTTCTGATGTTGCAGAATCTGATGATGAAGTAGAAATACCAAGTGCAAAAAGACGACATATTCAAcagaaagaaaatacaaaacaatgtTCACAATCAACTATTGTTTCTGATAATAATCCAATTTCAGATAATAAAAGTACTGAAATTAACCAAACAACGTATAATTATGAATGTATGAGAACATACATTAAAGTAGGGGACACAGAATGTAATAATCAGTCTACTGAACCACGCAGCGTCAATAATTCTGAAAGTACAAAAGAATGTTCAAAACAACCAAACATATTAAAACGCAGGTTATTATTACAGTCTAAAAAAGAATCTACAGAAGAAACTgatgaaaatatttaccaGACAAATATTTCTGATAAAAGTCATAAAGACTTAAAAGTACAAAAACTCGATGTAAACAATTCTTTGAACCTTAACAGTAATCAAGAAGATGGCATCATGTATGTTACTGTGAAAGGATCTAAAccgaatgaaatattgttagTAAAAGTTAAGAAAATGGATAAACcattagagaaaaaagaagataaatctacagggaaaaagaattttgatattaaacCAATGGATAAGATTTTAAAACGATATGAAACATTagttacaaaagaaaaagatttatttccAGAACGAACAAAAAAGTTAGAAATAAGAGAGCAGATTATAGAAGAACAAATAGAAGAATACAAGAAAAAGCGAGAAAAAGTATTAGGTGGACATGCCAATATTGTTGCACCTCCAAAATTTGAGGAATCTCGTTATTTTAAGCGTAATGAAAGTCAAGATAATCAAAGATCTTTTACACATATAGAAAATGATTCTGCTGTAAACATACAGTTTAATAAAGATGATAGTGAATTTAATGCAACTATTACAATTGAAGATGATGCTATAGAAATTGCAGAATCAGCCAAAGAAAAGTCAACAAATGAAAAAGCGTATGTAAATACTGAAGAATATTTATCACATTTAGCAAAGCTTAAATTGAAATGGGAAGaagcaaaaaagaagaaagaatatCTTCAAAAAGAACTTGATGAATCTTATACAGAaggaaatattgaaaagttaGCAAGAATTTtaggggaaaaaaaaaaaaatttgcaagactttcaagattatttaaaacaacgtaaaattgtaattacaaGATTAAAAGATGAGGatattatttctctttatgAAGACAGAAACAATGCAGTCCTTAAAAACAACTTACCTGACTTAATAGATGAAAGTCAACCAGCAGATTATATTCCAGAAGAACATTATTTAGAATGTGATTATTGTCCAGAAACATTTGCTTCTAAAGAAGTTCTTGAAGAACATTTAAGATCACATGACTATAAAATTATGCATTTTTGTGAAGATTGCATGGAAGAATTTCCAACAAATAAAGCAAAACGAAATCATAATGtgatttgtataaaaaaattactatGTAAATATTGTGACATGATGTTAGATTCAAAAGGAAAAAAGCGTCAGCATGAACAAAAACATTGTGATAGTATGTATGGACAATTATGTGATGTATGTGGTGAAAAGTTTAAACATCAAGGAACATTGGATCAACATGTCAAAACACAACACATGAATTGGGAGAAAATATATCAATGTACAAAGTGTCCTAAAAAGTTTGCATTCAAACAAAAACTTAGCTTTCATTTGAAATCTGTACACACAACTTTAAGAGCCTATTTGTGTGAGGATTGTGGAGCTGATTTTAAAAATCCTGCAAGTCTTAGACATCATAGAATACGTAAACATCAACCTGTAAGTAATAAGAGAGAATGCCCAGTTTGCCATAAATTAGTACCGTTTTATAGCCTTTCTAAACACATGCATACTCATAAAGCATATACTATTCAGTGTCCACACTGTGacaaaatgtttaaaaatagtTCAACTTTAAAGCAACATGTAAGAATTCATGAAGATCAACGTCAATATCGATGTGATACTTGTGGTGTTGGATTTAATAGAAGAGATGGTTTAAGGTTACACATGAGAGTACATGAGAAGACCGATAGTAGGGGATTAAAAGAATGTTCATGTCAAGTATGTGGTGAAAAGTTTCCAAATCATTCAACACTTGTTATACATAGGAACCGAGTTCATAAGGATGGTAGACAATACACTTGTCATATATGTAATAGATCAATGATTTCAACTAGATCATTAGAGTGGCATATGTCTCATATACACAATGAAACACTTCCTGGTGTAAAGGAAGGGATAGATGGGGCACCAGAAAAAAGAAGGGCATCATGTTATCGTTGTAGTAAGACATTCAAAACAGAAATGATTTTGAGAACGCATATTAAAAACACACATATGGAGAAAGATCCTATGAAATGTTTAGATTGtgaattaacatttatttccgAAGTGAGGTTAAGACATCATATGATGGTCACACATAACAGATTAGAAGGAACTATACCATGCCCACATTGTCCAAAGAGATTTGTGAATCAAATCAGATTAAAAACTCATTTGGTATCTCATTCTGAAGATAGGCCACACACTTGTGAAATCTGTGGGtttaaattgaaaactaaGATACAGTTGGTTAAACATCAACAAAATAGGCACAGCGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCACTTGTATGTCATGAAAGAACTCATACAAATGAACGACCATATTCTTGCAGTGTATGTAGGCaacgttttaaatatttaggtgataaaaataaacatgAAAGACGACATGAAAGCTTAGGAGGATCTGGATTTAAAAGGATAATACTTAGTCGAAATAGTAAACCTAAACTATTAGAAGATTCTTCTTGTTCTGAACACGaaagtttaaataatataaagtgTCAAGTTCCTGAAAGTGAATATCAAGAACAGACAGATCAACAATTTGAAGAAGAACAAATAGTTAAGTTTGAAGAAGAACAAATAGTTAAATTTGAAGAAGAACAGATTAAATTTGAAGAACAAGAAATAACAGAAGAATATGAACAAGTATATGAACAGGAATATGAAGAGACATCCAGAGAAGCTTCTGATGCAGCAGAAGTTATAATGAATATGGAAGACACAACAGTTTACACAGAAGAAGTAACTACGGATAACATTGAACCTACAGAAATTATGGCAGATGAAATAAtgacaaatgaaatattacaatcAGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGGAAAATACAAGTGATTCCAGTGATGTTATCTTTACCTGATTTATCCGATGCAAATACAGAGGTCAATTTAGCTACTGCATCcattatgtataataattaa
Protein Sequence: MNRSKMQHTEVKNKDHNYSEVKLHSIQHTASNILNVCDSDVKTTCKSNKTGLVSNKEIFGQIKDINELKKITPRVKLLTHDANSLNELTKISLHNKISTQKKLSISEQTKQELKKYCRTCAGLKLPLVDIFSEKGNQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLRSIHITLTDTATKNAELNKMQPVESFEKQMENAVECNTKNPSTSKEYTSVPKISTIFSLKDNEDIVKDKKLCTDYKESESKVEPGIFEDTTVLQNSDDNESIEEFDPDDPPFQPDSSDVAESDDEVEIPSAKRRHIQQKENTKQCSQSTIVSDNNPISDNKSTEINQTTYNYECMRTYIKVGDTECNNQSTEPRSVNNSESTKECSKQPNILKRRLLLQSKKESTEETDENIYQTNISDKSHKDLKVQKLDVNNSLNLNSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKEDKSTGKKNFDIKPMDKILKRYETLVTKEKDLFPERTKKLEIREQIIEEQIEEYKKKREKVLGGHANIVAPPKFEESRYFKRNESQDNQRSFTHIENDSAVNIQFNKDDSEFNATITIEDDAIEIAESAKEKSTNEKAYVNTEEYLSHLAKLKLKWEEAKKKKEYLQKELDESYTEGNIEKLARILGEKKKNLQDFQDYLKQRKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKEVLEEHLRSHDYKIMHFCEDCMEEFPTNKAKRNHNVICIKKLLCKYCDMMLDSKGKKRQHEQKHCDSMYGQLCDVCGEKFKHQGTLDQHVKTQHMNWEKIYQCTKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVSNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNETLPGVKEGIDGAPEKRRASCYRCSKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFISEVRLRHHMMVTHNRLEGTIPCPHCPKRFVNQIRLKTHLVSHSEDRPHTCEICGFKLKTKIQLVKHQQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIILSRNSKPKLLEDSSCSEHESLNNIKCQVPESEYQEQTDQQFEEEQIVKFEEEQIVKFEEEQIKFEEQEITEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTTDNIEPTEIMADEIMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLSDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684931;
90% Identity: iTF_00220747;
80% Identity: -