Basic Information

Insect: Bombus polaris
Gene Symbol: gtf3a
Assembly: GCA_014737335.1
Location: JACXIO010000148.1:87779-92080[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6e-05 0.0061 17.2 0.1 2 23 695 716 694 716 0.97

2 16 0.5 51 4.9 1.2 3 23 748 768 746 768 0.97

3 16 0.00023 0.023 15.4 1.2 3 23 777 798 776 798 0.98

4 16 0.0095 0.96 10.3 2.9 1 23 805 828 805 828 0.95

5 16 8.2e-05 0.0084 16.8 0.7 1 23 834 857 834 857 0.94

6 16 1.1 1.1e+02 3.8 2.5 2 23 865 885 865 885 0.94

7 16 1.2e-07 1.2e-05 25.7 2.1 2 23 891 912 890 912 0.97

8 16 1.9e-06 0.0002 21.9 0.2 1 23 918 940 918 940 0.99

9 16 0.00048 0.049 14.4 2.4 2 23 952 974 951 974 0.95

10 16 0.0068 0.7 10.7 2.5 1 23 980 1003 980 1003 0.96

11 16 0.11 12 6.9 2.2 3 23 1025 1046 1024 1046 0.94

12 16 0.0026 0.26 12.1 0.9 2 23 1053 1075 1052 1075 0.96

13 16 0.00012 0.012 16.3 0.6 2 23 1083 1104 1082 1104 0.95

14 16 0.0027 0.27 12.0 2.7 1 23 1110 1133 1110 1133 0.95

15 16 0.28 29 5.7 3.2 2 23 1140 1161 1139 1161 0.96

16 16 0.0083 0.84 10.5 2.6 1 23 1167 1189 1167 1189 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6e-05	0.0061	17.2	0.1	2	23	695	716	694	716	0.97
2	16	0.5	51	4.9	1.2	3	23	748	768	746	768	0.97
3	16	0.00023	0.023	15.4	1.2	3	23	777	798	776	798	0.98
4	16	0.0095	0.96	10.3	2.9	1	23	805	828	805	828	0.95
5	16	8.2e-05	0.0084	16.8	0.7	1	23	834	857	834	857	0.94
6	16	1.1	1.1e+02	3.8	2.5	2	23	865	885	865	885	0.94
7	16	1.2e-07	1.2e-05	25.7	2.1	2	23	891	912	890	912	0.97
8	16	1.9e-06	0.0002	21.9	0.2	1	23	918	940	918	940	0.99
9	16	0.00048	0.049	14.4	2.4	2	23	952	974	951	974	0.95
10	16	0.0068	0.7	10.7	2.5	1	23	980	1003	980	1003	0.96
11	16	0.11	12	6.9	2.2	3	23	1025	1046	1024	1046	0.94
12	16	0.0026	0.26	12.1	0.9	2	23	1053	1075	1052	1075	0.96
13	16	0.00012	0.012	16.3	0.6	2	23	1083	1104	1082	1104	0.95
14	16	0.0027	0.27	12.0	2.7	1	23	1110	1133	1110	1133	0.95
15	16	0.28	29	5.7	3.2	2	23	1140	1161	1139	1161	0.96
16	16	0.0083	0.84	10.5	2.6	1	23	1167	1189	1167	1189	0.98

Sequence Information

Coding Sequence: ATGCAGCACACTGAAGTTAAAAACAAGGATCATAATTATAGTGAAGTAAAATTACATAGTATTCAGCATACTGCTAGTAATATCCTAAATGTATGTGACAGTGATGTTAAAACAACATGTAAATCAAACAAAACTGGATTAGTATCAAATAAAGAAATATTCGGTCAGATTAAAGATATTAATGAATTAAAAAAAATTACACCGCGTGTAAAATTGTTGACTCATGATGCAAATAGTTTAAATGAATTAACTAAAATTTCTTTGCACAATAAAGTATCTGCGCAAAAGAAACTATCAATATCAGAACAAACAAAACAGGAATTAAAAAAGTATTGTAGGACTTGCGCCGGTTTGAAACTTCCATTAGTTGATATTTTTAGTGAAAAAGGTAATCAAATGAGATTAAGTCAACAAATTAAGCATTTAGAAGAAATAAATCCATATGATAGTTTATCAACTCAAATGTGTATGGATTGTATTTGTGACTTAAAAATGAGTTATAAGTTTTTTATGCAAATTAAAAAAGCAGAAGTTAAATTAAGATCTATTCACATTACTCTCACAGATACAGCAACAAAAAATGCAGAATTAAATAAAATGCAGCCTGTAGGAAGTTTCGAAAAACAGGTGGAAAATGCTGTTGAGTGTAATACAAAAAATCCGTCTACAAATCATAAAGAATCAGAAAGTAAGGTTGAACCTGGAATTTTTGAAGACACCACTGTTCTCCAAAATAGTGATGATAATGAATCAATAGAAGAATTTGATCCAGATGATCCTCCTTTTCAACCTGATAGTTCTGATGTTGCAGAGTCTGATGATGAAGTAGAAATACCAAGTGCAAAAAGACGACATATTCAACAGAAAGAAAATACAAAACAATGTTCACAATCAGCTATTGTTTCTGGTAATAATTCAATTTCAGATAATAAAAGTACTGAAATTAACCAAACAACGTATAATTATGAATGTATGAGAACATACATTAAAGTAGGGGACGCAGAATGTAATAATCAGTCTACTGAACCACGCAGCGTCAATAACTCTGAAAGTACAAAAGAATGTTCAAAACAACCAAACATATTAAAACGCAGGTTATTATTACAGTCTAAAAAAGAATCTACAGAAGAAACTGATGAAAATATTTACCAGACAAATATTTCTGATAAAAGTCATAAAGACTTAAAAGTACAAAAACTTGATGTAAACAATTCTTTGAACCTTAACAGTAATCAAGAAGATGGCATCATGTATGTTACTGTGAAAGGATCTAAACCAAATGAAATATTGTTAGTAAAAGTCAAGAAAATGGATAAACCATTAGAGAAAAAAGAAGATAAATCTACAGGGAAAAAGAATTTTGACATTAAACCAATGGATAAGATTTTAAAACGATATGAAACATTAGTTACAAAAGAAAAAGATTTATTTCCAGAACGAACAAAAAAGTTAGAAATAAGAGAGCAGATTATAGAAGAACAAATAGAAGAATACAAGAAAAAGCGAGAAAAAGTATTAGGCGGACATGCCAATATTGTTGCACCTCCAAAATTTGAGGAATCTCGTCACTTTAAGCGTAATGAAAGTCAAGATAATCAAAGATCTTTTACACATATAGAAAATGATTCTGCTGTAAATATACAGTTTAATAAAGATGATAGTGAATTTAATGCAACTATTACAGTTGAAGATGATGCTATAGAAATTGCAGAATCAACGAAGAAAAAGTCTACAAATGAAAAATCTTATATAAATACTGAAGAATATTTATCACATTTAGCAAAGCTTAGATTGAAATGGGAAGAAGCAAAAAAGAAGAAAGAATATCTTCAAAAAGAACTTGATGAATCTTATACAGAAGGAAATATTGAGAAGTTAGCAAGAATTTTAGGGGAAAAAAAAAAAAATTTGCAAGACTTTCAAGATTATTTAAAACAACGTAAAATTGTAATTACAAGATTAAAAGATGAGGATATTATTTCTCTTTATGAAGACAGAAATAATGCAGTCCTTAAAAACAACTTACCTGACTTAATAGATGAAAGTCAACCAGCAGATTATATTCCAGAAGAACATTATTTAGAATGTGATTATTGTCCAGAAACATTTGCTTCTAAAGAAGTTCTTGAAGAACATTTGAGATCACATGACTATAAAATTATGCATTTTTGTGAAGATTGCATGGAAGAATTTCCAACAAATAAAGCAAAACGAAATCATGATTGTACAAAAAAATTACTATGTAAACAGTGTGGCGAGAAGTTAGAATCAAAAGGGAAAAAGCGTCAGCATGAACAAAAACATTGTGATAATGAATATGGACAACTATGTGATGTATGTGGTGAAAAGTTTAAACATCAAGGAACATTGGATCAACATGTCAAAACACAACACATGAATTGGGAGAAAATATATCAATGTACAAAGTGCCCTAAAAAGTTTGCATTCAAACAAAAACTTAGCTTTCATTTGAAATCTGTACACACAACTTTAAGAGCCTATTTGTGTGAGGACTGTGGAGCTGATTTTAAAAATCCTGCAAGTCTTAGACATCATAGAATACGTAAACATCAACCTGTAAGTAATAAGAGAGAATGCCCAGTTTGCCATAAATTAGTACCATTTTATAGCCTTTCTAAACATATGCATACTCATAAAGCATATACTATTCAGTGTCCACATTGTGACAAAATGTTTAAAAATAGTTCAACTTTAAAGCAACATGTAAGAATTCATGAAGATCAACGTCAATATCGATGTGATACTTGTGGTGTTGGATTTAATAGAAGAGATGGTTTAAGGTTACACATGAGAGTACATGAGAAGACCGATAGTAGAGGATTAAAAGAATGTTCATGTCAAGTATGTGGTGAAAAGTTTCCAAATCACTCAACACTTGTTATACATAGGAACCGAGTTCATAAGGATGGTAGACAATACACTTGTCATATATGTAATAGATCAATGATTTCAACTAGATCATTAGAGTGGCATATGTCTCATATACACAATGAAACACTTCCTGGTGTAAAGGAAGGGATAGATGGGGCACCAGAAAAAAGAAGGGCATCATGTTATCGTTGTAGCAAGACATTCAAAACAGAAATGATTTTGAGAACGCATATTAAAAACACACATATGGAGAAAGATCCTATGAAATGTTTAGATTGTGAATTAACATTTATTTCCGAAGTGAGGTTAAGACATCATATGATGGTCACACATAACAGATTAGAAGGAACTATACCATGCCCACATTGTCCAAAGAGATTTGTGAATCAAATCAGATTAAAAACTCATTTGGTATCTCATTCTGAAGATAGGCCACACACTTGTGAAATCTGTGGGTTTAAATTGAAAACTAAGATACAGTTGGTTAAACATCGACAAAATAGGCACAGCGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCACTTGTATGTCATGAAAGAACTCATACAAATGAACGACCATATTCTTGCAGTGTATGTAGGCAACGTTTTAAATATTTAGGTGATAAAAATAAACATGAAAGACGACATGAAAGCTTAGGAGGATCTGGATTTAAAAGGATAATACTTAGTCGAAATAGTAAACCTAAACTATTAGAAGATTCTTCTTGTTCTGAACACGAAAGTTTAAATAATATAAAGTGTCAAGTTCCTGAAAGTGAATATCAAGAACAGACAGATCAACAATTTGAAGAAGAACAAATAATTAAATTTGAAGAACAAGAAATAACAGAAGAATATGAACAAGTATATGAACAGGAATATGAAGAGACATCCAGAGAAGCTTCTGATGCAGCAGAAGTTATAATGAATATGGAAGACACAACAGTTTACACAGAAGAAGTAACTGCAGATAATATTGAACCTACAGAAATTATGGCAGATGAAATAATGACAAATGAAATATTACAATCAGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGGAAAATACAAGTGATTCCAGTGATGTTATCTTTACCTGATTTATCCGATGCAAATACAGAGGTCAATTTAGCTACTGCATCCATTATGTATAATAATTGA
Protein Sequence: MQHTEVKNKDHNYSEVKLHSIQHTASNILNVCDSDVKTTCKSNKTGLVSNKEIFGQIKDINELKKITPRVKLLTHDANSLNELTKISLHNKVSAQKKLSISEQTKQELKKYCRTCAGLKLPLVDIFSEKGNQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLRSIHITLTDTATKNAELNKMQPVGSFEKQVENAVECNTKNPSTNHKESESKVEPGIFEDTTVLQNSDDNESIEEFDPDDPPFQPDSSDVAESDDEVEIPSAKRRHIQQKENTKQCSQSAIVSGNNSISDNKSTEINQTTYNYECMRTYIKVGDAECNNQSTEPRSVNNSESTKECSKQPNILKRRLLLQSKKESTEETDENIYQTNISDKSHKDLKVQKLDVNNSLNLNSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKEDKSTGKKNFDIKPMDKILKRYETLVTKEKDLFPERTKKLEIREQIIEEQIEEYKKKREKVLGGHANIVAPPKFEESRHFKRNESQDNQRSFTHIENDSAVNIQFNKDDSEFNATITVEDDAIEIAESTKKKSTNEKSYINTEEYLSHLAKLRLKWEEAKKKKEYLQKELDESYTEGNIEKLARILGEKKKNLQDFQDYLKQRKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKEVLEEHLRSHDYKIMHFCEDCMEEFPTNKAKRNHDCTKKLLCKQCGEKLESKGKKRQHEQKHCDNEYGQLCDVCGEKFKHQGTLDQHVKTQHMNWEKIYQCTKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVSNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNETLPGVKEGIDGAPEKRRASCYRCSKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFISEVRLRHHMMVTHNRLEGTIPCPHCPKRFVNQIRLKTHLVSHSEDRPHTCEICGFKLKTKIQLVKHRQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIILSRNSKPKLLEDSSCSEHESLNNIKCQVPESEYQEQTDQQFEEEQIIKFEEQEITEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPTEIMADEIMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLSDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684931;
90% Identity: iTF_00220747;
80% Identity: -