Basic Information

Insect: Bombus terrestris
Gene Symbol: gtf3a
Assembly: GCA_000214255.1
Location: NW:828518-834565[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 4.6e-05 0.0028 17.2 0.1 2 23 729 750 728 750 0.97

2 16 0.39 24 4.8 1.2 3 23 782 802 780 802 0.97

3 16 0.00018 0.011 15.3 1.2 3 23 811 832 810 832 0.98

4 16 0.0073 0.45 10.2 2.9 1 23 839 862 839 862 0.95

5 16 6.4e-05 0.0039 16.7 0.7 1 23 868 891 868 891 0.94

6 16 0.88 54 3.7 2.5 2 23 899 919 899 919 0.94

7 16 9.4e-08 5.7e-06 25.6 2.1 2 23 925 946 924 946 0.97

8 16 1.5e-06 9.2e-05 21.9 0.2 1 23 952 974 952 974 0.99

9 16 0.00038 0.023 14.3 2.4 2 23 986 1008 985 1008 0.95

10 16 0.0053 0.33 10.7 2.5 1 23 1014 1037 1014 1037 0.96

11 16 0.089 5.4 6.8 2.2 3 23 1059 1080 1058 1080 0.94

12 16 0.002 0.12 12.0 0.9 2 23 1087 1109 1086 1109 0.96

13 16 0.00025 0.015 14.9 1.0 2 23 1117 1138 1116 1138 0.95

14 16 0.0021 0.13 12.0 2.7 1 23 1144 1167 1144 1167 0.95

15 16 0.22 13 5.6 3.2 2 23 1174 1195 1173 1195 0.96

16 16 0.0064 0.39 10.4 2.6 1 23 1201 1223 1201 1223 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	4.6e-05	0.0028	17.2	0.1	2	23	729	750	728	750	0.97
2	16	0.39	24	4.8	1.2	3	23	782	802	780	802	0.97
3	16	0.00018	0.011	15.3	1.2	3	23	811	832	810	832	0.98
4	16	0.0073	0.45	10.2	2.9	1	23	839	862	839	862	0.95
5	16	6.4e-05	0.0039	16.7	0.7	1	23	868	891	868	891	0.94
6	16	0.88	54	3.7	2.5	2	23	899	919	899	919	0.94
7	16	9.4e-08	5.7e-06	25.6	2.1	2	23	925	946	924	946	0.97
8	16	1.5e-06	9.2e-05	21.9	0.2	1	23	952	974	952	974	0.99
9	16	0.00038	0.023	14.3	2.4	2	23	986	1008	985	1008	0.95
10	16	0.0053	0.33	10.7	2.5	1	23	1014	1037	1014	1037	0.96
11	16	0.089	5.4	6.8	2.2	3	23	1059	1080	1058	1080	0.94
12	16	0.002	0.12	12.0	0.9	2	23	1087	1109	1086	1109	0.96
13	16	0.00025	0.015	14.9	1.0	2	23	1117	1138	1116	1138	0.95
14	16	0.0021	0.13	12.0	2.7	1	23	1144	1167	1144	1167	0.95
15	16	0.22	13	5.6	3.2	2	23	1174	1195	1173	1195	0.96
16	16	0.0064	0.39	10.4	2.6	1	23	1201	1223	1201	1223	0.98

Sequence Information

Coding Sequence: ATGAATAGGTCAAAGATGCAGCACACTGAAGTTAAAAACAAGGATCATAATTATAGTGAAGTAAAATTACATAGTATTCAGCATACTGCTAGTAATATCCTAAATGTATGTGACAGTGATGTTAAAACAACATGTAAATCAAACAAAACTGGATTAGtatcgaataaagaaatattcggtcagattaaagatattaatgaattaaaaaaaattacaccGCGTGTAAAATTGTTGACTCATGATGCAAATAgtttaaatgaattaactaaaatttctttgCACAATAAAGTATCTGCGCAAAAAAAACTATCAATATcagaacaaataaaacagGAATTAAGAAAGTATTGTAGGACTTGTGCTGGTTTGAAACTTCCGTTAGTTGATATTTTTAGTGAAAAAGGTAATCAAATGAGATTAAGTCAACAAATTAAGCatttagaagaaataaatccATATGATAGTTTATCAACTCAAATGTGTATGGATTGTATTTGTGACTTAAAAATgagttacaaattttttatgcaaattaaaaaagcagAAGTTAAATTAAGATCTATTCATATTACTCTCACAGATACAGCGACAAAAAATgcagaattaaataaaatgcagCCTGTAGGAAGTTTTGAAAAACAGATAGAAAATGCTGTTGAGTGTGATACAAAAAATCCATCTACAAGTAAAGAATATACTTCTGTACCAAAAATATCTGcaattttttcgttaaaagataatgaaaatattatgaatgatAAGGAACTTTGTACAGATCATAAAGAATCAGAAAGTAAGGTTGAACCTGGAATTTTTGAAGACACCACTGTCCTCCAAAATAGTGATGATAATGAATCAATAGAAGAATTTGATCCAGATGATCCTCCTTTTCAACCTGATAGTTCTGATGTTGCAGAGTCTGATGATGAAGTAGAAATACCAAGTGCAAAAAGACGACATATTcaacagaaagaaaatataaaacaatgttCACAATCAGCTATTGTTTCTGATAATAATCTAATTTCAGATAATAAAAGTACTGAAATTAGCCAAACAACGTATAATTATGAATGTATGAGAACATACATTAAAATAGGGGACACAGAATGTAATAATCAGTCTACTGAACCACGCAGCGTCAATAATTCTGAAAGTACAAAAGAATGTTCAAAACAACCAAACATATTAAAACGCAGGTTATTATTACAGTCTAAAAAAGAATCTACAGAAGAAactgatgaaaatatttaccagacaaatatttctgataaaagTCATAAAGActtaaaagtacaaaaactCGATGTAAACAATTCTTTGAACCTTAATAGTAATCAAGAGGATGGCATCATGTATGTTACTGTGAAAGGATCTAAAccgaatgaaatattgttagtaaaagtaaaaaaaatggataaaccattagagaagaaagaagataaacctatagggaaaaagaattttgacATTAAACCAATGGATAAGATTTTAAAACGATATGAAACATTagttacaaaagaaaaagatttatttccaGAACGAACAAAAAAGTTAGAAATAAGAGAGCAGATTATAGAAGAACAAATAGAAGAATACaagaaaaagcgagaaaaagtATTAGGCGGGCATGCCAATATTGTTGCACCTCCAAAATTTGAGGAATCTCGTCACTTTAAACGTAATGAAAGTCAAGATAATCAAAGATCTTTTACACATATAGAAAATGATTCTGCTGTAaacatacattttaataaagatgATAGTGAATTTAATGCAACTATTACAATTGAAGATGATGCTATAGAAATTGCAGAATCGGCCAAGAAAAAGTCTACAAATGAAAAAACTTATATAAATACTGAAGAATATTTATCACATTTAGCAAAGCTTAAATTGAAATGGGAAGaagcgaaaaagaagaaagaatatcTTCAAAAAGAACTTGATGAATCTTATACAGAAGGAAATATTGAGAAGTTAGCAAGAATTTTAggaaaaaaaaaaaatttgcaagactttcaagattatttaaaacaacgtaaaattgtaattacaagATTAAAAGATGAGgatattatttctctttatgaAGACAGAAATAATGCAGTCCTTAAAAACAACTTACCTGACTTAATAGATGAGAGTCAACCAGCAGATTATATTCCAGAAGAACATTATTTAGAATGTGATTATTGTCCAGAAACATTTGCTTCTAAAGAAGTTCTTGAAGAACATTTGAGATCAcatgattataaaattatgcatttttgTGAAGATTGCATGGAAGAATTTCCAACAAATAAAGCAAAACGAAATCATGattgtacaaaaaaattaCTATGTAAACAGTGTGGCGAGAAGTTAGAatcaaaaggaaaaaagcGTCAGCATGAACAAAAACATTGTGATAATGAGTATGGACAATTATGTGATGTATGTGGTGAAAAGTTTAAACATCAAGGAACATTGGATCAACATGTCAAAACACAACACATGAATTGggagaaaatatatcaatgtaCAAAGTGTCCTAAAAAGTTTGCATTCAAACAAAAACTTAGCTTTCATTTGAAATCTGTACACACAACTTTAAGAGCCTATTTGTGTGAGGACTGTGGAGCTGATTTTAAAAATCCTGCAAGTCTTAGACATCATAGAATACGTAAACATCAACCTGTAAGTAATAAGAGAGAATGCCCAGTTTGCCATAAATTAGTACCATTTTATAGCCTTTCTAAACACATGCATACTCATAAAGCATATACTATTCAGTGTCCACACTGTgacaaaatgtttaaaaatagttCAACTTTAAAGCAACATGTAAGAATTCATGAAGATCAACGTCAATATCGATGTGATACTTGTGGTGTTGGATTTAATAGAAGAGATGGTTTAAGGTTACACATGAGAGTACATGAGAAGACCGATAGTAGAGGATTAAAAGAATGTTCATGTCAAGTATGTGGTGAAAAGTTTCCAAATCATTCAACACTTGTTATACATAGGAACCGAGTTCATAAAGATGGTAGACAATACACTTGTCATATATGTAATAGATCAATGATTTCAACTAGATCATTAGAGTGGCATATGTCTCATATACACAATGAAACACTTCCTGGTGTGAAGGAAGGGTTAGATGGGACACCAGAAAAAAGAAGGGCATCATGTTATCGTTGTAGTAAGACATTCAAAACAGAAATGATTTTGAGAACGCACATTAAAAACACACATATGGAGAAAGATCCTATGAAATGTTTAGATTGtgaattaacatttatttctgaAGTGAGGTTAAGACATCATATGATGGTCACACATAACAGATTAGAAGGAACTATACCGTGCCCACATTGTTCAAAGAGATTTGTGAATCAAATCAGATTAAAAACTCATTTGGTATCTCATTCTGAAGATAGGCCACATACTTGTGAAATCTGTggatttaaattgaaaactaAGATACAGTTGGTTAAACATCGACAAAATAGGCACAGCGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCACTTGTATGTCATGAAAGAACTCATACAAATGAACGACCATATTCTTGCAGTGTATGTAGGcaacgttttaaatatttaggtgataaaaataaacatgaaAGACGACATGAAAGCTTAGGAGGATCTGGATTTAAAAGGATAATACTTAGTCGAAATAGTAAACCTAAACTATTAGAAGATTCTTCTTGTTCTGAACACgaaagtttaaataatataaagtgtCAAGTTCCTGAAAGTGAATATCAAGAACAGACAGATCAACAATTTGAAGAAGAACAAATAGTTAAGTTTGAAGAAGAACAAATAGttaaatttgaagaagaacagattaaatttgaagaacAAGAAATAACAGAAGAATATGAACAAGTATATGAACAgGAATATGAAGAGACATCCAGAGAAGCTTCTGATGCAGCAGAAGTTATAATGAATATGGAAGACACAACAGTTTACACAGAAGAAGTAACTGCAGATAACATTGAACCTACAGAAATTATGGCAGATGAAATAatgacaaatgaaatattacaatcaGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGGAAAATACAAGTGATTCCAGTGATGTTATCTTTACCTGATTTATCTGATGCAAATACAGAGGTCAATTTAGCTACTGCATccattatgtataataattga
Protein Sequence: MNRSKMQHTEVKNKDHNYSEVKLHSIQHTASNILNVCDSDVKTTCKSNKTGLVSNKEIFGQIKDINELKKITPRVKLLTHDANSLNELTKISLHNKVSAQKKLSISEQIKQELRKYCRTCAGLKLPLVDIFSEKGNQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLRSIHITLTDTATKNAELNKMQPVGSFEKQIENAVECDTKNPSTSKEYTSVPKISAIFSLKDNENIMNDKELCTDHKESESKVEPGIFEDTTVLQNSDDNESIEEFDPDDPPFQPDSSDVAESDDEVEIPSAKRRHIQQKENIKQCSQSAIVSDNNLISDNKSTEISQTTYNYECMRTYIKIGDTECNNQSTEPRSVNNSESTKECSKQPNILKRRLLLQSKKESTEETDENIYQTNISDKSHKDLKVQKLDVNNSLNLNSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKEDKPIGKKNFDIKPMDKILKRYETLVTKEKDLFPERTKKLEIREQIIEEQIEEYKKKREKVLGGHANIVAPPKFEESRHFKRNESQDNQRSFTHIENDSAVNIHFNKDDSEFNATITIEDDAIEIAESAKKKSTNEKTYINTEEYLSHLAKLKLKWEEAKKKKEYLQKELDESYTEGNIEKLARILGKKKNLQDFQDYLKQRKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKEVLEEHLRSHDYKIMHFCEDCMEEFPTNKAKRNHDCTKKLLCKQCGEKLESKGKKRQHEQKHCDNEYGQLCDVCGEKFKHQGTLDQHVKTQHMNWEKIYQCTKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVSNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNETLPGVKEGLDGTPEKRRASCYRCSKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFISEVRLRHHMMVTHNRLEGTIPCPHCSKRFVNQIRLKTHLVSHSEDRPHTCEICGFKLKTKIQLVKHRQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIILSRNSKPKLLEDSSCSEHESLNNIKCQVPESEYQEQTDQQFEEEQIVKFEEEQIVKFEEEQIKFEEQEITEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPTEIMADEIMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLSDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684931;
90% Identity: iTF_00220747;
80% Identity: -