Bbre010699.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus breviceps
Gene Symbol
ZFX
Assembly
GCA_014825925.1
Location
CM026179.1:8783326-8787706[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.2 86 3.7 0.1 3 23 24 44 23 44 0.94
2 15 2.9 2.2e+02 2.5 3.4 1 23 893 916 893 916 0.80
3 15 0.00046 0.034 14.4 2.1 3 23 1001 1022 999 1022 0.96
4 15 0.013 0.94 9.9 0.5 2 23 1035 1056 1034 1056 0.97
5 15 1.4e-05 0.001 19.2 3.1 2 23 1059 1080 1058 1080 0.97
6 15 0.012 0.86 10.0 0.3 1 23 1086 1108 1086 1108 0.95
7 15 2.3e-05 0.0017 18.5 4.5 2 23 1115 1136 1114 1137 0.95
8 15 0.1 7.6 7.0 3.7 5 23 1150 1168 1149 1168 0.97
9 15 2.1e-05 0.0015 18.7 1.5 3 23 1175 1196 1174 1196 0.97
10 15 0.017 1.2 9.5 0.3 2 23 1212 1232 1211 1232 0.97
11 15 6.3e-05 0.0046 17.2 0.7 1 20 1238 1257 1238 1260 0.92
12 15 0.00032 0.024 14.9 2.8 1 23 1268 1290 1268 1290 0.99
13 15 0.0022 0.16 12.3 3.2 1 23 1296 1318 1296 1318 0.97
14 15 3.9e-06 0.00029 20.9 3.9 1 23 1324 1346 1324 1346 0.99
15 15 0.0014 0.1 12.9 6.3 1 23 1352 1374 1352 1375 0.96

Sequence Information

Coding Sequence
atgtataaagaaaataccTCAGACACAATGGATGCAGTAAGCAATGGAGCTTCAGGAAGTGCAGTGGCTTGTCCAGTCTGTACCCTCTATCTACGCGAGGGTATCAGCTTACAAAGACATTTGGATACTCATCCAAAAGAACAAGTCATCGAAGCTCTTATCAAAGCTAGTACCAATTCCTCAAATGTACAACAGACACAGTTATCATCATCAGCACCTCCAGCATCTTCAGCTATACAATCATCCCAAAATACACCTCAAGTTGCACAGAATACTCATCTATCGGCTCAATCTCCATATCCTATAGGACCTATTTTCGAATGTCCACCTATCGGTACTGTGATGCCACCTCAGTTTGCTTCATTTAGTTATCAACAGTTTGTAAATAATGGCACTATGATGATACCACAATATGCAATGGCTCCACAAGCTAATCAAATGATGCAAATGCTATATAATCCATATGGTATGTATCAGCAGCAACAAATACCAACTGTTCAAATGATTTCGCCAGTCACAGCCATACCAAACACCACTAGAGTCAGGCCAGTGGTAACTATGGCTGGTGAAACAACTGGTAGGACTGCCATTGCTGTACCTGTAAATAATTCCGAGccaaaacaaattttacctGAGATTTTACCTGAATCGGAGCAAGAGTCTGAACAAATGTTATCAGATATCAACCTTCCAGTTTCTCCTCCATCATTAAACGAAGATAATTCTATGCAGCAAAATGAAAGTGAAACTAGTACAATTCAAATAGAACAAGAAGGAGAGGAGCCCCTTGGTTCAAGTACAGATCAGCATACTGTGCAAGATGAATATGATAGCATTCCAAGATCATTGGCAATTACTTGTAATGTCAATGTTACTACAGATGATAAAGTTGAGAGTGTATTGCCGGATATTGATAATGGGGAATCATCGTGCGTTGTTACTACAAATGTGCAGTGTAAGTCTATTCATTATGAATCGTCAGAAATGCAGGAGTATGTACACAGATATgaagatgatgatgataataataaagttattatGCCTGAAGTATCACCAATGGTAACAGAAAATGAGACAGAAAATGCAACTAATGAAAAAGTTCCTCACagagaagaaataagaaaaaatgaaggTACCTCAGCAGAAATGCCTGTAGAAAATACAGTAAAAGCACCAGCTCAGCCTGAAGTAGAACAATTAGAACGTCTTTTAATCACTATTatggaaaatgaatttaataatactcCACAGAAAGAATCCAATTTTGaagatgataaaaagaaaagtaaagatacaaagaaaaatacttcTCCTGAAAGGGCTGAGAGTGTAATACATGAAATAACTAGTAATAATCCCATTGAATATGAAAACAGTTGTAAATCTgatgtaaaagtaaaagttaatCAAAGCTCGGAAATTAATATAGATaatgatgaaaataaaagttcttgtcttttatacaattataaaaacagTTTGTCTGCACCTCCATCACCTATTGTACAAAGAAGACCCCATAGAACTTATTCTGTTCATTCAGATTTTAGTTCAAATGAACACCTTAATTTTTATCCAATTGGTTTTGATGCAAGCGCATTGCACGATGAGGAATATGatgaagatgaaaaaaatgaaacagaagaTAATTTTGATGAGGCAGATATGGAAATAGAGGAAATACCTAGCCCACATACTCCTTTCATTAAATATGATGAAAATGCAGACAATGTTAGATCTCATACTCCATTATCTGCAAGTAGTGGTATTTCTGTATTAAGAGTTAGAAAGGATCTTAGTAAACCATGTTCACCTGCTTCTATCCATTCATTTTGTCATATGGATGCTAATGGTATAAGCCACGATGAAGAAAGTAATGTAGCAATGGATGAATCACTAGAAAAAGATCCTATTGATTGTTCTTTAGTTGAACAAGATGTGAAAACTGATCAGTTAGAATTTTCCTTATgcaaaaatgagaaaaaaatggaagaagatTCTGCATATCAATCTGGAATTAGTGACCATATGAGTTCATTTTCTACAATTCATTCACAACATTCTCAGCAATCAACATTAATGGATGAATCATATAACATGccaaataaaagtaataatcaTGTAAATTTATCAGAATCTAGTGATGTCGCAAGTAGTTCTGACTCAAAGAGTTTTCATTCATCTAAATCAATTATACAAAAACAATCTGTGGAACTCCTTAGTTTAAATGAAGATGCCCATGCAGGTCCAATGAATGTGTTTGAATTTGATGGGCTTCAAATCTTAGTTCCTAGTACATTCATAAGTGATTCTTCACAAAAAGCAGTTAGTGGAACCAGCCAACAATCTATGGCAAGTAGTGAAGGTGGAATAGGTATAGATGAAGAAGTTAAAAGCATTAATATGAGAGCTGATGAAACTATGCCACCCAGAGGTGAACTATCAGAACAAGAAAGCAATGGATGTACAGAACAATCAGCTTGGCAGTTATATGCTGGTCAAGAATCATCAAGAATGTCAACATCTTATGATCTAATGGCACGTGAAAGTTGGGAAGAATCTGATGGATCAGACAATGAAATTACAGGCCCATTATTAGATAGCAGATCTTTAGCAACACATTTTACATCAAGTTTATTTTTAGATCGAGATAGAAAAACTCCTACAAAAAGAATGTTCAAATGTTATCATTGCCCTGAAGTATTTGATTGTCCGAAAGAACGCAGAGTACATAGTACCACCGCGCACAAAGAAGCTGGTCCGAGTAGCAGTAGAGAATCTACAGAACAACCTGAAGTAAAGGATATTAAGTTATTGGATGGCCGTATGAATgtatttgaagatatttttgtaCCAGGTTTACATGTTCAACAAGTTTATCACCAGCAACCACTGTTACATCAACTTCAACCACCACAATCATGTACAGATGTAACTACAAAAGTAGAATCTgatcaaaaaattgaaacactAGTAATACCATCAAACATTGAAGTGATCTGCACCCTTTGCAATCAGAGATTTAGTAGTGAAAAATCATTACAACTACATCATAGAAGAGTACATATTACAGAAACAACAAAACGAATTCGTGAGAGCACCAAGTGTCAGATATGTCACGAAGAATTTCCTTCGGTTCTATTGTATAATGcccatttaaaaatacatccATTAGAATGTAGTCAATGtggaaagtatttttatagaaaacaaaatttcaaattgcacATGAAACGACATTTAGGAATTAAACCATTTCCATGTACTGTTTGTGACAAAGCATTTTTAACAAAACAGAAGTTAGATGAACATACCAATGGTCATACCGGGAATGCACCTGTTAAGTGTAATCTTTGCAATGAAACATTTCGCAGATATTCAAATCTAACACAGCACAAAAATAGACAtcatttgaatataaaaaaaaaattaaaagattacatATGTCATTGTGGTGAGGTTTTTCATACAAAGAAAAAGCTAGCTTGGCATAAAGAAACACATGATGAAAAACCCAAAGCATGTACATATTGTAATGAAAGATTCATTCACATGGCCAGCCTGACTAGACATATGCGCCGAGCTCATAATAAAAGATTCGTTCCAGATGCTCAAAGAGAGAGCGAAAATGTTGAATGTCCTGTATGTAAgtgtatttatttacgatcTTCCTTAGCAGTGCATATGCGAGTACATAATGGTGAAAGACCATATGAATGTCAAGTTTGCTCTAAAGCATTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACTCACGCTGCCCGTAGCACCAAACCTTTCAAGTGTAATCAGTGTAGTGGCGCGTTTTACCGGCACAGTGATTATACTGCTCATATGAATTCTCATAGAAACGTGCGTCCTTATACCTGTAACTATTGCGGAGCGCAGTTCatacgaaaatataattgtttaagGCATGTAAAGGAACATGAAGAGAACAAAGCATATACATGTGACGTTTGCAACAAAACTTTTCATAGATCATATTATCTGAAAGAACACTTGCGAGTACATTCAGGTGCCAGACCATATACATGTCATATTTGTGGAAAGTCTAGCGGTACGAAATCCAATCATAATAAACATGTCAGAATTCATCATGCACGAGAACCTGTAAATAccgaaaattaa
Protein Sequence
MYKENTSDTMDAVSNGASGSAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASTNSSNVQQTQLSSSAPPASSAIQSSQNTPQVAQNTHLSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTAIPNTTRVRPVVTMAGETTGRTAIAVPVNNSEPKQILPEILPESEQESEQMLSDINLPVSPPSLNEDNSMQQNESETSTIQIEQEGEEPLGSSTDQHTVQDEYDSIPRSLAITCNVNVTTDDKVESVLPDIDNGESSCVVTTNVQCKSIHYESSEMQEYVHRYEDDDDNNKVIMPEVSPMVTENETENATNEKVPHREEIRKNEGTSAEMPVENTVKAPAQPEVEQLERLLITIMENEFNNTPQKESNFEDDKKKSKDTKKNTSPERAESVIHEITSNNPIEYENSCKSDVKVKVNQSSEINIDNDENKSSCLLYNYKNSLSAPPSPIVQRRPHRTYSVHSDFSSNEHLNFYPIGFDASALHDEEYDEDEKNETEDNFDEADMEIEEIPSPHTPFIKYDENADNVRSHTPLSASSGISVLRVRKDLSKPCSPASIHSFCHMDANGISHDEESNVAMDESLEKDPIDCSLVEQDVKTDQLEFSLCKNEKKMEEDSAYQSGISDHMSSFSTIHSQHSQQSTLMDESYNMPNKSNNHVNLSESSDVASSSDSKSFHSSKSIIQKQSVELLSLNEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSGTSQQSMASSEGGIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESDGSDNEITGPLLDSRSLATHFTSSLFLDRDRKTPTKRMFKCYHCPEVFDCPKERRVHSTTAHKEAGPSSSRESTEQPEVKDIKLLDGRMNVFEDIFVPGLHVQQVYHQQPLLHQLQPPQSCTDVTTKVESDQKIETLVIPSNIEVICTLCNQRFSSEKSLQLHHRRVHITETTKRIRESTKCQICHEEFPSVLLYNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNKRFVPDAQRESENVECPVCKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSGAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN